ZA773459B - 4-trifluoromethyl-benzoic acid derivatives and process of making the same and pharmaceutical-compositions containing same - Google Patents

4-trifluoromethyl-benzoic acid derivatives and process of making the same and pharmaceutical-compositions containing same

Info

Publication number: ZA773459B
Authority: ZA; South Africa
Prior art keywords: same; trifluoromethyl; pharmaceutical; making; benzoic acid
Prior art date: 1976-06-10

Application number

ZA00773459A

Other languages

English (en)

Inventor

E Francia

A Marin

Original Assignee

Uriach & Cia Sa J

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-10

Filing date

1977-06-08

Publication date

1978-05-30

1977-06-08 Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J

1978-05-30 Publication of ZA773459B publication Critical patent/ZA773459B/xx

Links

SWKPKONEIZGROQ-UHFFFAOYSA-N 4-trifluoromethylbenzoic acid Chemical class OC(=O)C1=CC=C(C(F)(F)F)C=C1 SWKPKONEIZGROQ-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)

ZA00773459A 1976-06-10 1977-06-08 4-trifluoromethyl-benzoic acid derivatives and process of making the same and pharmaceutical-compositions containing same ZA773459B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/694,523 US4096252A (en)	1976-06-10	1976-06-10	4-Trifluoromethylbenzoic acid derivatives as thromboembolic agents

Publications (1)

Publication Number	Publication Date
ZA773459B true ZA773459B (en)	1978-05-30

Family

ID=24789174

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00773459A ZA773459B (en)	1976-06-10	1977-06-08	4-trifluoromethyl-benzoic acid derivatives and process of making the same and pharmaceutical-compositions containing same

Country Status (15)

Country	Link
US (2)	US4096252A (xx)
JP (1)	JPS5914007B2 (xx)
AU (3)	AU2588077A (xx)
BE (1)	BE855588A (xx)
CA (1)	CA1090705A (xx)
DE (2)	DE2641556A1 (xx)
ES (1)	ES459855A1 (xx)
FI (1)	FI771842A (xx)
FR (1)	FR2354335A1 (xx)
GB (1)	GB1588633A (xx)
GR (1)	GR63213B (xx)
IE (1)	IE45962B1 (xx)
NL (1)	NL7706433A (xx)
PT (1)	PT66637B (xx)
ZA (1)	ZA773459B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4397790A (en) *	1980-12-03	1983-08-09	Monsanto Company	Isophosphinolinone derivatives
DE3127237A1 (de) *	1981-07-10	1983-01-20	Hoechst Ag, 6000 Frankfurt	Magenvertraegliche arzneiformen von xanthinderivaten und verfahren zu ihrer herstellung
US4766389A (en) *	1986-09-03	1988-08-23	Extrude Hone Corporation	Capacitor array sensors tactile and proximity sensing and methods of use thereof
GB8927503D0 (en) *	1989-12-04	1990-02-07	Kronem Systems Inc	Enzyme-amplified lanthanide chelate luminescence
IT1243410B (it) *	1990-12-17	1994-06-10	Donegani Guido Ist	Procedimento per la funzionalizzazione di trifluorometilbenzeni
ES2136581B1 (es) *	1998-05-27	2000-09-16	Uriach & Cia Sa J	Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
US6509377B1 (en) *	1999-05-26	2003-01-21	J. Uriach & Cia, S.A.	Use of a 2-hydroxy-4-trifluoromethylbenzoic acid derivatives as inhibitors of the activation of the nuclear transcription factor NF-κB
ES2154242B1 (es) *	1999-09-03	2001-10-16	Uriach & Cia Sa J	Nuevos sistemas polimericos biocompatibles portadores de triflusal o htb.
ES2190373B1 (es) *	2001-12-07	2004-10-16	J. URIACH & CIA, S.A.	Uso del acido 2-hidroxi- o 2-acetiloxi-4-trifluorometilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero.
KR100503267B1 (ko) *	2002-09-17	2005-07-22	(주)리드젠	2-아세틸옥시-4-트리플루오로메틸 벤조산의 제조 방법
CN1308282C (zh) *	2005-01-11	2007-04-04	山东师范大学	一种4－三氟甲基乙酰水杨酸的催化合成方法
US20100069326A1 (en) *	2008-02-14	2010-03-18	Wasimul Haque	Combination Therapies to Treat Cardio- and Cerebro-Vascular Disorders
WO2009100534A1 (en) *	2008-02-14	2009-08-20	Kardiatech, Inc.	Combination therapy to treat vascular disorders
CN101695496A (zh) *	2009-10-15	2010-04-21	苏春华	一种含有三氟柳和氯吡格雷的药物组合物
ES2389348B1 (es)	2011-04-05	2013-09-23	Simbec Ibérica Sl	Polvo compuesto de triflusal, uso del mismo para granulados, comprimidos o sobres, procedimiento para la preparación de dicho polvo compuesto y uso de una o mas ciclodextrinas para estabilizar el triflusal.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE25085E (en) *		1961-11-21		Therapeutic use of ortho-carboxy-sub
CA621838A (en) *		1961-06-13	E. Fancher Otis	Salts of phosphosalicylic acid
FR1174923A (fr) *	1956-05-10	1959-03-18	Ciba Geigy	Procédé de préparation de dérivés phosphorylés d'acides organiques hydroxylés
US3019253A (en) *	1958-05-15	1962-01-30	Pennsalt Chemicals Corp	Acetyl-4-trifluoromethyl salicylic acid

1976
- 1976-06-10 US US05/694,523 patent/US4096252A/en not_active Expired - Lifetime
- 1976-09-15 DE DE19762641556 patent/DE2641556A1/de active Granted
- 1976-09-15 DE DE2661085A patent/DE2661085C2/de not_active Expired
- 1976-12-30 US US05/755,851 patent/US4110442A/en not_active Expired - Lifetime
1977
- 1977-06-01 GR GR53603A patent/GR63213B/el unknown
- 1977-06-03 CA CA279,838A patent/CA1090705A/en not_active Expired
- 1977-06-06 PT PT66637A patent/PT66637B/pt unknown
- 1977-06-07 AU AU25880/77A patent/AU2588077A/en not_active Expired - Fee Related
- 1977-06-07 ES ES459855A patent/ES459855A1/es not_active Expired
- 1977-06-08 ZA ZA00773459A patent/ZA773459B/xx unknown
- 1977-06-09 FR FR7717707A patent/FR2354335A1/fr active Granted
- 1977-06-10 FI FI771842A patent/FI771842A/fi not_active Application Discontinuation
- 1977-06-10 NL NL7706433A patent/NL7706433A/xx not_active Application Discontinuation
- 1977-06-10 GB GB24415/77A patent/GB1588633A/en not_active Expired
- 1977-06-10 BE BE178361A patent/BE855588A/xx not_active IP Right Cessation
- 1977-06-10 JP JP52068731A patent/JPS5914007B2/ja not_active Expired
- 1977-06-10 IE IE1197/77A patent/IE45962B1/en not_active IP Right Cessation
1986
- 1986-02-27 AU AU54156/86A patent/AU5415686A/en not_active Abandoned
1988
- 1988-12-22 AU AU27477/88A patent/AU2747788A/en not_active Abandoned

Also Published As

Publication number	Publication date
FR2354335A1 (fr)	1978-01-06
GB1588633A (en)	1981-04-29
NL7706433A (nl)	1977-12-13
IE45962L (en)	1977-12-10
FR2354335B1 (xx)	1982-11-12
DE2641556A1 (de)	1977-12-29
FI771842A (xx)	1977-12-11
PT66637B (en)	1978-11-09
DE2661085C2 (xx)	1988-04-07
JPS5914007B2 (ja)	1984-04-02
DE2641556C2 (xx)	1988-12-29
US4096252A (en)	1978-06-20
IE45962B1 (en)	1983-01-12
AU2747788A (en)	1989-04-27
AU5415686A (en)	1986-07-31
US4110442A (en)	1978-08-29
GR63213B (en)	1979-10-09
CA1090705A (en)	1980-12-02
BE855588A (fr)	1977-10-03
PT66637A (en)	1977-07-01
JPS52156831A (en)	1977-12-27
AU2588077A (en)	1978-12-14
ES459855A1 (es)	1978-04-01

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