ZA763990B - Pyrrolo(2,1-b)(3)benzazepines - Google Patents

Pyrrolo(2,1-b)(3)benzazepines

Info

Publication number
ZA763990B
ZA763990B ZA00763990A ZA763990A ZA763990B ZA 763990 B ZA763990 B ZA 763990B ZA 00763990 A ZA00763990 A ZA 00763990A ZA 763990 A ZA763990 A ZA 763990A ZA 763990 B ZA763990 B ZA 763990B
Authority
ZA
South Africa
Prior art keywords
benzazepines
pyrrolo
Prior art date
Application number
ZA00763990A
Other languages
English (en)
Inventor
J Rokach
C Rooney
J Atkinson
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA763990B publication Critical patent/ZA763990B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00763990A 1975-07-02 1976-07-02 Pyrrolo(2,1-b)(3)benzazepines ZA763990B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59243675A 1975-07-02 1975-07-02

Publications (1)

Publication Number Publication Date
ZA763990B true ZA763990B (en) 1978-02-22

Family

ID=24370639

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00763990A ZA763990B (en) 1975-07-02 1976-07-02 Pyrrolo(2,1-b)(3)benzazepines

Country Status (18)

Country Link
JP (1) JPS527996A (xx)
AU (1) AU499122B2 (xx)
BE (1) BE843678A (xx)
CA (1) CA1092105A (xx)
CH (5) CH626366A5 (xx)
CY (1) CY1091A (xx)
DE (2) DE2661014C2 (xx)
ES (1) ES449432A1 (xx)
FR (1) FR2315935A1 (xx)
GB (1) GB1499047A (xx)
GR (1) GR60851B (xx)
HK (1) HK60580A (xx)
HU (1) HU177866B (xx)
MY (1) MY8100227A (xx)
NL (1) NL188287C (xx)
PT (1) PT65295B (xx)
SE (1) SE424076B (xx)
ZA (1) ZA763990B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148903A (en) * 1977-07-28 1979-04-10 Merck & Co., Inc. Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
JPH0487401U (xx) * 1990-12-06 1992-07-29
US6271392B1 (en) 1994-10-07 2001-08-07 Rhone-Poulenc Inc. Intermediates useful for the synthesis of 1-arylpyrrole pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3428677A (en) * 1962-09-24 1969-02-18 Merck & Co Inc Chemical compounds and methods of preparing same
US3499037A (en) * 1966-05-31 1970-03-03 Merck & Co Inc Preparation of trifluoromethyl substituted dibenzocycloheptenes

Also Published As

Publication number Publication date
DE2629877A1 (de) 1977-01-20
NL7607347A (nl) 1977-01-04
CA1092105A (en) 1980-12-23
GB1499047A (en) 1978-01-25
JPS527996A (en) 1977-01-21
DE2661014A1 (xx) 1985-07-04
GR60851B (en) 1978-08-31
MY8100227A (en) 1981-12-31
FR2315935A1 (fr) 1977-01-28
CH626366A5 (en) 1981-11-13
CY1091A (en) 1980-12-27
AU499122B2 (en) 1979-04-05
AU1548876A (en) 1978-01-05
FR2315935B1 (xx) 1978-11-17
DE2661014C2 (xx) 1989-01-05
JPH0132225B2 (xx) 1989-06-29
BE843678A (fr) 1977-01-03
PT65295A (en) 1976-07-01
HK60580A (en) 1980-11-07
SE424076B (sv) 1982-06-28
CH626617A5 (en) 1981-11-30
CH626616A5 (en) 1981-11-30
NL188287B (nl) 1991-12-16
DE2629877C2 (xx) 1989-01-05
CH626893A5 (en) 1981-12-15
HU177866B (en) 1982-01-28
SE7607534L (sv) 1977-01-03
CH626618A5 (en) 1981-11-30
ES449432A1 (es) 1977-12-16
PT65295B (en) 1978-05-10
NL188287C (nl) 1992-05-18

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