ZA200709987B - Combination of HCV protease inhibitors with a surfactant - Google Patents
Combination of HCV protease inhibitors with a surfactantInfo
- Publication number
- ZA200709987B ZA200709987B ZA200709987A ZA200709987A ZA200709987B ZA 200709987 B ZA200709987 B ZA 200709987B ZA 200709987 A ZA200709987 A ZA 200709987A ZA 200709987 A ZA200709987 A ZA 200709987A ZA 200709987 B ZA200709987 B ZA 200709987B
- Authority
- ZA
- South Africa
- Prior art keywords
- surfactant
- combination
- protease inhibitors
- hcv protease
- hcv
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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- A61K38/08—Peptides having 5 to 11 amino acids
-
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
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- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Obesity (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68694505P | 2005-06-02 | 2005-06-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200709987B true ZA200709987B (en) | 2008-11-26 |
Family
ID=37482240
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200709987A ZA200709987B (en) | 2005-06-02 | 2007-11-19 | Combination of HCV protease inhibitors with a surfactant |
Country Status (17)
Country | Link |
---|---|
US (1) | US7772178B2 (xx) |
EP (1) | EP1919478B1 (xx) |
JP (2) | JP5160415B2 (xx) |
KR (1) | KR20080021634A (xx) |
CN (1) | CN101212970B (xx) |
AR (1) | AR055198A1 (xx) |
AU (1) | AU2006252553B2 (xx) |
BR (1) | BRPI0610737A2 (xx) |
CA (1) | CA2611155A1 (xx) |
ES (1) | ES2572980T3 (xx) |
MX (1) | MX2007015270A (xx) |
NO (1) | NO20076613L (xx) |
NZ (1) | NZ563365A (xx) |
PE (1) | PE20070011A1 (xx) |
TW (1) | TWI428138B (xx) |
WO (1) | WO2006130628A2 (xx) |
ZA (1) | ZA200709987B (xx) |
Families Citing this family (55)
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MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
MY145081A (en) | 2004-02-27 | 2011-12-15 | Schering Corp | Sulfur compounds as inhibitors of hepatitis c virus ns3 serine protease |
US7816326B2 (en) * | 2004-02-27 | 2010-10-19 | Schering Corporation | Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease |
WO2006130686A2 (en) * | 2005-06-02 | 2006-12-07 | Schering Corporation | Hcv protease inhibitors in combination with food |
MX2008001166A (es) * | 2005-07-25 | 2008-03-18 | Intermune Inc | Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis c. |
ATE493409T1 (de) | 2005-10-11 | 2011-01-15 | Intermune Inc | Verbindungen und verfahren zur inhibierung der replikation des hepatitis-c-virus |
WO2007120595A2 (en) * | 2006-04-11 | 2007-10-25 | Novartis Ag | Amines for the treatment of hcv |
US8420122B2 (en) | 2006-04-28 | 2013-04-16 | Merck Sharp & Dohme Corp. | Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same |
US7935670B2 (en) | 2006-07-11 | 2011-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8343477B2 (en) | 2006-11-01 | 2013-01-01 | Bristol-Myers Squibb Company | Inhibitors of hepatitis C virus |
US7772180B2 (en) | 2006-11-09 | 2010-08-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7763584B2 (en) | 2006-11-16 | 2010-07-27 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7888464B2 (en) | 2006-11-16 | 2011-02-15 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8003604B2 (en) | 2006-11-16 | 2011-08-23 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
CL2008001381A1 (es) | 2007-05-10 | 2008-11-03 | Intermune Inc Y Array Biopharma Inc | Compuestos derivados de tripeptidos que contienen heterociclos nitrogenados; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una infeccion de hepatitis c o vih. |
US8309685B2 (en) | 2007-12-21 | 2012-11-13 | Celgene Avilomics Research, Inc. | HCV protease inhibitors and uses thereof |
US8293705B2 (en) | 2007-12-21 | 2012-10-23 | Avila Therapeutics, Inc. | HCV protease inhibitors and uses thereof |
TW201546079A (zh) | 2007-12-21 | 2015-12-16 | Celgene Avilomics Res Inc | Hcv蛋白酶抑制劑及其用途(一) |
US8202996B2 (en) | 2007-12-21 | 2012-06-19 | Bristol-Myers Squibb Company | Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide |
PE20091522A1 (es) * | 2007-12-21 | 2009-10-29 | Novartis Ag | Composicion farmaceutica solida que contiene 3-(1.h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-quinazolin-4-il]-pirrol-2,5-diona |
CN104557861A (zh) | 2007-12-21 | 2015-04-29 | 阿维拉制药公司 | Hcv蛋白酶抑制剂和其用途 |
US8163921B2 (en) | 2008-04-16 | 2012-04-24 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7964560B2 (en) | 2008-05-29 | 2011-06-21 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
EP2300491B1 (en) | 2008-05-29 | 2016-01-06 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
EP2323631A1 (en) * | 2008-08-07 | 2011-05-25 | Schering Corporation | Pharmaceutical formulations of an hcv protease inhibitor in a solid molecular dispersion |
US8188137B2 (en) | 2008-08-15 | 2012-05-29 | Avila Therapeutics, Inc. | HCV protease inhibitors and uses thereof |
US8207341B2 (en) | 2008-09-04 | 2012-06-26 | Bristol-Myers Squibb Company | Process or synthesizing substituted isoquinolines |
UY32099A (es) | 2008-09-11 | 2010-04-30 | Enanta Pharm Inc | Inhibidores macrocíclicos de serina proteasas de hepatitis c |
US8563505B2 (en) | 2008-09-29 | 2013-10-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8044087B2 (en) | 2008-09-29 | 2011-10-25 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8283310B2 (en) | 2008-12-15 | 2012-10-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
WO2010138889A1 (en) | 2009-05-28 | 2010-12-02 | Concert Pharmaceuticals, Inc. | Peptides for the treatment of hcv infections |
US8232246B2 (en) * | 2009-06-30 | 2012-07-31 | Abbott Laboratories | Anti-viral compounds |
CN103534256B (zh) | 2010-12-30 | 2016-08-10 | 益安药业 | 大环丙型肝炎丝氨酸蛋白酶抑制剂 |
PE20140039A1 (es) | 2010-12-30 | 2014-03-01 | Enanta Pharm Inc | Inhibidores de serina proteasa de hepatitis c a base de macrociclicos de fenantridina |
US8957203B2 (en) | 2011-05-05 | 2015-02-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
US8691757B2 (en) | 2011-06-15 | 2014-04-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
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CN104023726A (zh) | 2011-10-21 | 2014-09-03 | 艾伯维公司 | 用于治疗hcv的一种或多种daa的联合治疗(例如,与abt-072或abt-333) |
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US20130123325A1 (en) | 2011-11-14 | 2013-05-16 | Sven Ruf | Use of boceprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases |
WO2014053533A1 (en) | 2012-10-05 | 2014-04-10 | Sanofi | Use of substituted 3-heteroaroylamino-propionic acid derivatives as pharmaceuticals for prevention/treatment of atrial fibrillation |
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US9643999B2 (en) | 2012-11-02 | 2017-05-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
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EP2914614B1 (en) | 2012-11-05 | 2017-08-16 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
EP2964664B1 (en) | 2013-03-07 | 2017-01-11 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
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CN103387510B (zh) * | 2013-08-08 | 2015-09-09 | 苏州永健生物医药有限公司 | 一种β-氨基-alpha-羟基环丁基丁酰胺盐酸盐的合成方法 |
EP3089757A1 (en) | 2014-01-03 | 2016-11-09 | AbbVie Inc. | Solid antiviral dosage forms |
JP7129703B2 (ja) | 2016-04-28 | 2022-09-02 | エモリー ユニバーシティー | アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用 |
CN116236580B (zh) * | 2020-02-21 | 2024-05-24 | 中国科学院上海药物研究所 | 金诺芬等老药及其组合物在抗单正链rna病毒中的应用 |
Family Cites Families (61)
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-
2006
- 2006-05-31 AU AU2006252553A patent/AU2006252553B2/en not_active Ceased
- 2006-05-31 WO PCT/US2006/021003 patent/WO2006130628A2/en active Application Filing
- 2006-05-31 AR ARP060102260A patent/AR055198A1/es unknown
- 2006-05-31 MX MX2007015270A patent/MX2007015270A/es active IP Right Grant
- 2006-05-31 NZ NZ563365A patent/NZ563365A/en not_active IP Right Cessation
- 2006-05-31 CA CA002611155A patent/CA2611155A1/en not_active Abandoned
- 2006-05-31 CN CN2006800195249A patent/CN101212970B/zh not_active Expired - Fee Related
- 2006-05-31 US US11/444,078 patent/US7772178B2/en not_active Expired - Fee Related
- 2006-05-31 PE PE2006000582A patent/PE20070011A1/es not_active Application Discontinuation
- 2006-05-31 JP JP2008514785A patent/JP5160415B2/ja not_active Expired - Fee Related
- 2006-05-31 BR BRPI0610737-0A patent/BRPI0610737A2/pt not_active IP Right Cessation
- 2006-05-31 EP EP06760571.7A patent/EP1919478B1/en active Active
- 2006-05-31 KR KR1020077028243A patent/KR20080021634A/ko not_active Application Discontinuation
- 2006-05-31 ES ES06760571.7T patent/ES2572980T3/es active Active
- 2006-06-01 TW TW095119307A patent/TWI428138B/zh not_active IP Right Cessation
-
2007
- 2007-11-19 ZA ZA200709987A patent/ZA200709987B/xx unknown
- 2007-12-21 NO NO20076613A patent/NO20076613L/no not_active Application Discontinuation
-
2012
- 2012-09-19 JP JP2012205626A patent/JP2012250996A/ja active Pending
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ES2572980T3 (es) | 2016-06-03 |
PE20070011A1 (es) | 2007-03-08 |
NO20076613L (no) | 2008-03-03 |
AU2006252553A1 (en) | 2006-12-07 |
CN101212970B (zh) | 2010-07-21 |
KR20080021634A (ko) | 2008-03-07 |
WO2006130628A2 (en) | 2006-12-07 |
US20070010431A1 (en) | 2007-01-11 |
AU2006252553B2 (en) | 2012-03-29 |
TW200716157A (en) | 2007-05-01 |
AR055198A1 (es) | 2007-08-08 |
BRPI0610737A2 (pt) | 2010-07-20 |
MX2007015270A (es) | 2008-02-21 |
WO2006130628A3 (en) | 2007-09-13 |
CN101212970A (zh) | 2008-07-02 |
JP5160415B2 (ja) | 2013-03-13 |
EP1919478B1 (en) | 2016-03-23 |
CA2611155A1 (en) | 2006-12-07 |
NZ563365A (en) | 2011-02-25 |
JP2012250996A (ja) | 2012-12-20 |
JP2008542383A (ja) | 2008-11-27 |
EP1919478A2 (en) | 2008-05-14 |
TWI428138B (zh) | 2014-03-01 |
US7772178B2 (en) | 2010-08-10 |
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