ZA200704168B - Lipid complexes coated with peg and their use - Google Patents
Lipid complexes coated with peg and their use Download PDFInfo
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- ZA200704168B ZA200704168B ZA200704168A ZA200704168A ZA200704168B ZA 200704168 B ZA200704168 B ZA 200704168B ZA 200704168 A ZA200704168 A ZA 200704168A ZA 200704168 A ZA200704168 A ZA 200704168A ZA 200704168 B ZA200704168 B ZA 200704168B
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- lipid
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- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
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- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
- A61K48/0033—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being non-polymeric
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- Y10T428/00—Stock material or miscellaneous articles
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Landscapes
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US (2) | US8852472B2 (xx) |
EP (2) | EP2992902A1 (xx) |
JP (1) | JP5292572B2 (xx) |
KR (1) | KR101366482B1 (xx) |
CN (1) | CN101287497B (xx) |
AU (1) | AU2005321469B2 (xx) |
BR (1) | BRPI0519468A2 (xx) |
CA (1) | CA2593032C (xx) |
DK (1) | DK1830888T3 (xx) |
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SG (1) | SG158175A1 (xx) |
WO (1) | WO2006069782A2 (xx) |
ZA (1) | ZA200704168B (xx) |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
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DK1527176T4 (en) | 2002-08-05 | 2017-07-03 | Silence Therapeutics Gmbh | ADDITIONAL NEW FORMS OF INTERFERRING RNA MOLECULES |
AU2005237764B2 (en) | 2004-05-05 | 2011-11-24 | Silence Therapeutics Gmbh | Lipids, lipid complexes and use thereof |
US8852472B2 (en) | 2004-12-27 | 2014-10-07 | Silence Therapeutics Gmbh | Coated lipid complexes and their use |
KR101418367B1 (ko) * | 2005-05-04 | 2014-07-25 | 녹손 파르마 아게 | 에이치엠지에이-결합 핵산 |
AU2007241370A1 (en) * | 2006-04-20 | 2007-11-01 | Silence Therapeutics Ag. | Lipoplex formulations for specific delivery to vascular endothelium |
RU2553561C2 (ru) * | 2006-07-21 | 2015-06-20 | Сайленс Терапьютикс Аг | Средства ингибирования экспрессии протеинкиназы 3 |
JP2010513354A (ja) | 2006-12-19 | 2010-04-30 | ノヴォソム アクチェンゲゼルシャフト | トランスフェクションエンハンサー要素を含む脂質および脂質集合体 |
EP2323695B1 (en) | 2008-08-19 | 2018-12-05 | Nektar Therapeutics | Complexes of small-interfering nucleic acids |
US8829179B2 (en) | 2009-02-18 | 2014-09-09 | Silence Therapeutics Gmbh | Means for inhibiting the expression of ANG2 |
US8916693B2 (en) | 2009-09-17 | 2014-12-23 | Nektar Therapeutics | Monoconjugated chitosans as delivery agents for small interfering nucleic acids |
US8359883B2 (en) * | 2009-11-13 | 2013-01-29 | Hasmukh Dholakiya | Gemstone setting |
WO2011120053A1 (en) | 2010-03-26 | 2011-09-29 | Mersana Therapeutics, Inc. | Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof |
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IL183775A (en) | 2016-12-29 |
ES2548515T3 (es) | 2015-10-19 |
HK1119090A1 (en) | 2009-02-27 |
CN101287497B (zh) | 2013-03-06 |
US8852472B2 (en) | 2014-10-07 |
JP5292572B2 (ja) | 2013-09-18 |
EP2992902A1 (en) | 2016-03-09 |
KR20070090956A (ko) | 2007-09-06 |
IL183775A0 (en) | 2007-09-20 |
HK1222541A1 (zh) | 2017-07-07 |
EP1830888B1 (en) | 2015-08-05 |
CA2593032A1 (en) | 2006-07-06 |
AU2005321469B2 (en) | 2012-04-05 |
WO2006069782A9 (en) | 2009-04-30 |
US20150031752A1 (en) | 2015-01-29 |
US20100062967A1 (en) | 2010-03-11 |
CN101287497A (zh) | 2008-10-15 |
SG158175A1 (en) | 2010-01-29 |
WO2006069782A3 (en) | 2007-04-12 |
EP1830888A2 (en) | 2007-09-12 |
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