ZA200600374B - Parastiticidal composition - Google Patents

Parastiticidal composition Download PDF

Info

Publication number: ZA200600374B
Authority: ZA; South Africa
Prior art keywords: closantel; formulation; ivermectin; pour; delivery system
Prior art date: 2003-07-12

Application number

ZA200600374A

Other languages

English (en)

Inventor

Blakely William

Cromie Lillian

Original Assignee

Norbrook Lab Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-12

Filing date

2006-01-13

Publication date

2007-05-30

2006-01-13 Application filed by Norbrook Lab Ltd filed Critical Norbrook Lab Ltd

2007-05-30 Publication of ZA200600374B publication Critical patent/ZA200600374B/en

Links

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238000009472 formulation Methods 0.000 description 54
JMPFSEBWVLAJKM-UHFFFAOYSA-N N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide Chemical compound ClC=1C=C(NC(=O)C=2C(=C(I)C=C(I)C=2)O)C(C)=CC=1C(C#N)C1=CC=C(Cl)C=C1 JMPFSEBWVLAJKM-UHFFFAOYSA-N 0.000 description 40
229950004178 closantel Drugs 0.000 description 40
AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 description 30
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PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 description 2
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BHFLSZOGGDDWQM-UHFFFAOYSA-N 1h-benzimidazole;carbamic acid Chemical class NC(O)=O.C1=CC=C2NC=NC2=C1 BHFLSZOGGDDWQM-UHFFFAOYSA-N 0.000 description 1
ZUXNHFFVQWADJL-UHFFFAOYSA-N 3,4,5-trimethoxy-n-(2-methoxyethyl)-n-(4-phenyl-1,3-thiazol-2-yl)benzamide Chemical compound N=1C(C=2C=CC=CC=2)=CSC=1N(CCOC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 ZUXNHFFVQWADJL-UHFFFAOYSA-N 0.000 description 1
VPWNQTHUCYMVMZ-UHFFFAOYSA-N 4,4'-sulfonyldiphenol Chemical class C1=CC(O)=CC=C1S(=O)(=O)C1=CC=C(O)C=C1 VPWNQTHUCYMVMZ-UHFFFAOYSA-N 0.000 description 1
IBSREHMXUMOFBB-JFUDTMANSA-N 5u8924t11h Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C(C)C)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 IBSREHMXUMOFBB-JFUDTMANSA-N 0.000 description 1
NQPDXQQQCQDHHW-UHFFFAOYSA-N 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole Chemical compound ClC=1C=C2NC(SC)=NC2=CC=1OC1=CC=CC(Cl)=C1Cl NQPDXQQQCQDHHW-UHFFFAOYSA-N 0.000 description 1
KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical class NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 description 1
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NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
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DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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230000003389 potentiating effect Effects 0.000 description 1
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HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
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150000003839 salts Chemical class 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
RPACBEVZENYWOL-XFULWGLBSA-M sodium;(2r)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate Chemical compound [Na+].C=1C=C(Cl)C=CC=1OCCCCCC[C@]1(C(=O)[O-])CO1 RPACBEVZENYWOL-XFULWGLBSA-M 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/609—Amides, e.g. salicylamide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Dentistry (AREA)
Environmental Sciences (AREA)
Plant Pathology (AREA)
Engineering & Computer Science (AREA)
Agronomy & Crop Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Pest Control & Pesticides (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Road Paving Structures (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200600374A 2003-07-12 2006-01-13 Parastiticidal composition ZA200600374B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0316377.1A GB0316377D0 (en)	2003-07-12	2003-07-12	Parasiticidal composition

Publications (1)

Publication Number	Publication Date
ZA200600374B true ZA200600374B (en)	2007-05-30

Family

ID=27742085

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200600374A ZA200600374B (en)	2003-07-12	2006-01-13	Parastiticidal composition

Country Status (29)

Country	Link
US (1)	US8993546B2 (ja)
EP (2)	EP1646425B1 (ja)
JP (1)	JP4677405B2 (ja)
KR (1)	KR101095419B1 (ja)
CN (1)	CN1822880B (ja)
AP (1)	AP2956A (ja)
AU (1)	AU2004257450B2 (ja)
BR (1)	BRPI0412522A (ja)
CA (1)	CA2532199C (ja)
CR (1)	CR8174A (ja)
DK (1)	DK1646425T3 (ja)
EA (1)	EA009602B1 (ja)
EC (1)	ECSP066360A (ja)
ES (1)	ES2390224T3 (ja)
GB (2)	GB0316377D0 (ja)
GE (1)	GEP20094648B (ja)
HK (1)	HK1096621A1 (ja)
HR (1)	HRP20120721T1 (ja)
IL (1)	IL173057A (ja)
MX (1)	MXPA06000135A (ja)
NO (1)	NO336181B1 (ja)
NZ (1)	NZ544973A (ja)
OA (1)	OA13188A (ja)
PL (1)	PL1646425T3 (ja)
PT (1)	PT1646425E (ja)
SI (1)	SI1646425T1 (ja)
TN (1)	TNSN06006A1 (ja)
WO (1)	WO2005007241A1 (ja)
ZA (1)	ZA200600374B (ja)

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AU2002952597A0 (en) *	2002-11-11	2002-11-28	Schering-Plough Pty. Limited	Topical parasiticide formulations and methods of treatment
GB0501220D0 (en) *	2005-01-21	2005-03-02	Norbrook Lab Ltd	Anthelmintic composition
GB0711957D0 (en) *	2007-06-21	2007-08-01	Syntopix Ltd	Formulations
CN101693009B (zh) *	2009-10-27	2010-12-01	纽素乐必佳（天津）药业集团有限公司	牛羊用抗寄生虫病氯氰碘柳胺钠透皮溶液及其制备方法
FR2991173B1 (fr)	2012-06-04	2015-11-06	Virbac	Composition veterinaire a administration cutanee a base d'oxyclozanide
CN103720652B (zh) *	2014-01-07	2016-09-28	王玉万	用泊洛沙姆和油性介质制备含阿维菌素类药物注射剂
WO2019054967A2 (en) *	2017-03-15	2019-03-21	Verano Ilac Sanayi Ve Ticaret Anonim Sirketi	VETERINARY COMPOSITION TO BE POURED COMPRISING EPRINOMECTIN
GB201715122D0 (en) *	2017-09-19	2017-11-01	Omnipharm Dev Ltd	Topical anti-infective formulation
KR20210113975A (ko) *	2018-10-12	2021-09-17	호비온 사이언티아 리미티드	마크로사이클릭 락톤 제제, 이의 제조방법, 및 안과 기생충에 대한 이차적인 병리를 치료하는데 있어서의 상기 제제의 용도

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AU2002952597A0 (en) *	2002-11-11	2002-11-28	Schering-Plough Pty. Limited	Topical parasiticide formulations and methods of treatment
AU2003275779B2 (en) *	2002-11-11	2009-02-05	Schering-Plough Pty. Limited	Topical parasiticide formulations and methods of treatment
AU2003900505A0 (en) *	2003-02-05	2003-02-20	Jurox Pty Ltd	Anthelmintic composition

2003
- 2003-07-12 GB GBGB0316377.1A patent/GB0316377D0/en not_active Ceased
2004
- 2004-07-12 ES ES04743347T patent/ES2390224T3/es not_active Expired - Lifetime
- 2004-07-12 SI SI200431947T patent/SI1646425T1/sl unknown
- 2004-07-12 PL PL04743347T patent/PL1646425T3/pl unknown
- 2004-07-12 PT PT04743347T patent/PT1646425E/pt unknown
- 2004-07-12 EP EP04743347A patent/EP1646425B1/en not_active Expired - Lifetime
- 2004-07-12 AU AU2004257450A patent/AU2004257450B2/en not_active Expired
- 2004-07-12 CA CA2532199A patent/CA2532199C/en not_active Expired - Fee Related
- 2004-07-12 GB GB0415541A patent/GB2403905B/en not_active Expired - Lifetime
- 2004-07-12 CN CN200480020006XA patent/CN1822880B/zh not_active Expired - Fee Related
- 2004-07-12 AP AP2006003506A patent/AP2956A/xx active
- 2004-07-12 BR BRPI0412522-3A patent/BRPI0412522A/pt not_active IP Right Cessation
- 2004-07-12 DK DK04743347.9T patent/DK1646425T3/da active
- 2004-07-12 OA OA1200600008A patent/OA13188A/en unknown
- 2004-07-12 MX MXPA06000135A patent/MXPA06000135A/es active IP Right Grant
- 2004-07-12 KR KR1020067000779A patent/KR101095419B1/ko not_active IP Right Cessation
- 2004-07-12 JP JP2006519991A patent/JP4677405B2/ja not_active Expired - Lifetime
- 2004-07-12 WO PCT/GB2004/003006 patent/WO2005007241A1/en active Application Filing
- 2004-07-12 EP EP10012261A patent/EP2286876A1/en not_active Withdrawn
- 2004-07-12 NZ NZ544973A patent/NZ544973A/en unknown
- 2004-07-12 EA EA200600237A patent/EA009602B1/ru not_active IP Right Cessation
- 2004-07-12 GE GEAP20049216A patent/GEP20094648B/en unknown
2006
- 2006-01-05 CR CR8174A patent/CR8174A/es unknown
- 2006-01-09 TN TNP2006000006A patent/TNSN06006A1/en unknown
- 2006-01-10 IL IL173057A patent/IL173057A/en not_active IP Right Cessation
- 2006-01-12 US US11/330,671 patent/US8993546B2/en active Active
- 2006-01-13 ZA ZA200600374A patent/ZA200600374B/en unknown
- 2006-02-10 EC EC2006006360A patent/ECSP066360A/es unknown
- 2006-02-10 NO NO20060676A patent/NO336181B1/no not_active IP Right Cessation
2007
- 2007-02-09 HK HK07101577.2A patent/HK1096621A1/xx not_active IP Right Cessation
2012
- 2012-09-10 HR HRP20120721TT patent/HRP20120721T1/hr unknown

Also Published As

Publication number	Publication date
NO336181B1 (no)	2015-06-08
NO20060676L (no)	2006-02-10
CN1822880A (zh)	2006-08-23
IL173057A0 (en)	2006-06-11
DK1646425T3 (da)	2012-09-17
US20060142216A1 (en)	2006-06-29
GB0316377D0 (en)	2003-08-13
EP2286876A1 (en)	2011-02-23
CR8174A (es)	2006-10-05
IL173057A (en)	2013-10-31
NZ544973A (en)	2008-09-26
ES2390224T3 (es)	2012-11-07
GEP20094648B (en)	2009-03-25
OA13188A (en)	2006-12-13
PT1646425E (pt)	2012-10-31
AP2956A (en)	2014-08-31
GB0415541D0 (en)	2004-08-11
WO2005007241A8 (en)	2005-03-10
ECSP066360A (es)	2006-10-31
US8993546B2 (en)	2015-03-31
HRP20120721T1 (hr)	2012-10-31
EP1646425A1 (en)	2006-04-19
BRPI0412522A (pt)	2006-09-19
JP2007528866A (ja)	2007-10-18
WO2005007241A1 (en)	2005-01-27
KR101095419B1 (ko)	2011-12-16
MXPA06000135A (es)	2006-04-07
GB2403905B (en)	2005-12-14
AU2004257450B2 (en)	2008-08-28
CA2532199C (en)	2012-05-15
EA200600237A1 (ru)	2006-06-30
AU2004257450A1 (en)	2005-01-27
PL1646425T3 (pl)	2013-01-31
AP2006003506A0 (en)	2006-02-28
CA2532199A1 (en)	2005-01-27
EP1646425B1 (en)	2012-08-22
CN1822880B (zh)	2012-07-11
GB2403905A (en)	2005-01-19
JP4677405B2 (ja)	2011-04-27
EA009602B1 (ru)	2008-02-28
TNSN06006A1 (en)	2007-10-03
SI1646425T1 (sl)	2012-12-31
KR20060113631A (ko)	2006-11-02
HK1096621A1 (en)	2007-06-08

Publication	Publication Date	Title
CA2476520C (en)	2009-08-11	Long acting parasiticidal composition containing a salicylanilide compound, a polymeric species and at least one other anti-parasitic compound
US6426333B1 (en)	2002-07-30	Spot-on formulations for combating parasites
US8993546B2 (en)	2015-03-31	Parasiticidal composition
US6998131B2 (en)	2006-02-14	Spot-on formulations for combating parasites
EP1887866B1 (en)	2017-12-06	Spot-on formulations for combating parasites
WO2003072112A1 (en)	2003-09-04	'long'-'acting' injectable parasiticidal composition
JP2012517994A (ja)	2012-08-09	高投与量ドラメクチン製剤
CN115671040B (zh)	2024-02-27	一种控制动物寄生虫感染的外用制剂