ZA200509247B - Pharmaceutical combination comprising modafinil and another drug - Google Patents

Pharmaceutical combination comprising modafinil and another drug Download PDF

Info

Publication number: ZA200509247B
Authority: ZA; South Africa
Prior art keywords: modafinil; drug; analeptic; composition; administration
Prior art date: 2003-05-16

Application number

ZA200509247A

Other languages

English (en)

Inventor

Rodney J Hughes

Jeffry L Vaught

Original Assignee

Cephalon Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-16

Filing date

2005-11-15

Publication date

2007-07-25

2005-11-15 Application filed by Cephalon Inc filed Critical Cephalon Inc

2007-07-25 Publication of ZA200509247B publication Critical patent/ZA200509247B/en

Links

239000003814 drug Substances 0.000 title claims description 157
229940079593 drug Drugs 0.000 title claims description 141
YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 title claims description 103
229960001165 modafinil Drugs 0.000 title claims description 99
239000002269 analeptic agent Substances 0.000 claims description 104
230000003555 analeptic effect Effects 0.000 claims description 96
239000000203 mixture Substances 0.000 claims description 49
239000002246 antineoplastic agent Substances 0.000 claims description 40
238000000034 method Methods 0.000 claims description 37
238000002651 drug therapy Methods 0.000 claims description 33
230000000694 effects Effects 0.000 claims description 30
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208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 20
208000035475 disorder Diseases 0.000 claims description 19
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-1 cisplatinum Chemical compound 0.000 claims description 15
208000024891 symptom Diseases 0.000 claims description 15
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ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims description 10
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RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims description 10
OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 claims description 10
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Landscapes

Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA200509247A 2003-05-16 2005-11-15 Pharmaceutical combination comprising modafinil and another drug ZA200509247B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US47130203P	2003-05-16	2003-05-16

Publications (1)

Publication Number	Publication Date
ZA200509247B true ZA200509247B (en)	2007-07-25

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ID=36788723

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200509247A ZA200509247B (en)	2003-05-16	2005-11-15	Pharmaceutical combination comprising modafinil and another drug

Country Status (4)

Country	Link
CN (1)	CN1791397A (es)
AR (1)	AR044360A1 (es)
CL (1)	CL2004001071A1 (es)
ZA (1)	ZA200509247B (es)

2004
- 2004-05-17 AR ARP040101682 patent/AR044360A1/es not_active Application Discontinuation
- 2004-05-17 CL CL2004001071A patent/CL2004001071A1/es unknown
- 2004-05-17 CN CN 200480013407 patent/CN1791397A/zh active Pending
2005
- 2005-11-15 ZA ZA200509247A patent/ZA200509247B/en unknown

Also Published As

Publication number	Publication date
CN1791397A (zh)	2006-06-21
AR044360A1 (es)	2005-09-07
CL2004001071A1 (es)	2005-03-04

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