ZA200502341B - Novel piperidine derivatives for use in the tretment of chemokine mediated disease states. - Google Patents
Novel piperidine derivatives for use in the tretment of chemokine mediated disease states. Download PDFInfo
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- ZA200502341B ZA200502341B ZA200502341A ZA200502341A ZA200502341B ZA 200502341 B ZA200502341 B ZA 200502341B ZA 200502341 A ZA200502341 A ZA 200502341A ZA 200502341 A ZA200502341 A ZA 200502341A ZA 200502341 B ZA200502341 B ZA 200502341B
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- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
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SE0202838A SE0202838D0 (sv) | 2002-09-24 | 2002-09-24 | Chemical compounds |
Publications (1)
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ZA200502341A ZA200502341B (en) | 2002-09-24 | 2005-03-18 | Novel piperidine derivatives for use in the tretment of chemokine mediated disease states. |
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EP (2) | EP1546130B1 (ru) |
JP (1) | JP2006503066A (ru) |
KR (1) | KR20050052511A (ru) |
CN (1) | CN1684952A (ru) |
AT (1) | ATE368656T1 (ru) |
AU (1) | AU2003259004B2 (ru) |
BR (1) | BR0314688A (ru) |
CA (1) | CA2497280A1 (ru) |
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SE (1) | SE0202838D0 (ru) |
WO (1) | WO2004029041A1 (ru) |
ZA (1) | ZA200502341B (ru) |
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AR033517A1 (es) * | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
RU2004100839A (ru) | 2001-07-02 | 2005-06-20 | Астразенека Аб (Se) | Производные пиперидина полезные в качестве модуляторов активности рецепторов хемокинов |
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US6949590B2 (en) * | 2002-01-10 | 2005-09-27 | University Of Washington | Hydrogels formed by non-covalent linkages |
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KR100896546B1 (ko) | 2004-08-10 | 2009-05-07 | 노파르티스 아게 | Ccr3 억제 활성을 갖는 피페라진 유도체 |
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TW200722419A (en) * | 2005-05-27 | 2007-06-16 | Astrazeneca Ab | Chemical compounds |
JP2009501793A (ja) | 2005-07-21 | 2009-01-22 | アストラゼネカ・アクチエボラーグ | 新規ピペリジン誘導体 |
EP1937666B1 (en) * | 2005-10-11 | 2012-02-22 | Schering Corporation | Substituted heterocyclic compounds with cxcr3 antagonist activity |
TWI433838B (zh) * | 2008-06-25 | 2014-04-11 | 必治妥美雅史谷比公司 | 作為趨化因子受體活性調節劑之六氫吡啶衍生物 |
GB0908394D0 (en) | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
GB0913636D0 (en) * | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
BR112013011737A2 (pt) | 2010-11-15 | 2016-08-09 | Univ Leuven Kath | composto, uso de um composto composição farmacêutica, e, método de tratamento ou prevenção de uma infecção por hiv |
WO2013096744A1 (en) | 2011-12-21 | 2013-06-27 | Novira Therapeutics, Inc. | Hepatitis b antiviral agents |
JP2015533782A (ja) | 2012-08-28 | 2015-11-26 | ヤンセン・サイエンシズ・アイルランド・ユーシー | スルファモイル−アリールアミド及びb型肝炎の治療のための薬剤としてのその使用 |
HUE034820T2 (en) | 2013-02-28 | 2018-02-28 | Janssen Sciences Ireland Uc | Sulphamoyl arylamides and their use as medicaments for the treatment of hepatitis B |
HUE033542T2 (en) | 2013-04-03 | 2017-12-28 | Janssen Sciences Ireland Uc | Their use as medicaments for the treatment of N-phenylcarboxamide derivatives and hepatitis B |
PT2997019T (pt) | 2013-05-17 | 2018-11-21 | Janssen Sciences Ireland Uc | Derivados de sulfamoíltiofenamida e o seu uso como medicamentos para o tratamento da hepatite b |
JO3603B1 (ar) | 2013-05-17 | 2020-07-05 | Janssen Sciences Ireland Uc | مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي |
PL3024819T3 (pl) | 2013-07-25 | 2018-08-31 | Janssen Sciences Ireland Uc | Pochodne piroloamidowe podstawione glioksamidem i ich zastosowanie jako leków do leczenia wirusowego zapalenia wątroby typu B |
ES2655518T3 (es) | 2013-10-23 | 2018-02-20 | Janssen Sciences Ireland Uc | Derivados de carboxamida y su uso como medicamentos para el tratamiento de la hepatitis B |
US10392349B2 (en) | 2014-01-16 | 2019-08-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
US9169212B2 (en) | 2014-01-16 | 2015-10-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
ES2792848T3 (es) | 2014-02-05 | 2020-11-12 | Novira Therapeutics Inc | Politerapia para el tratamiento de infecciones por VHB |
EA035848B1 (ru) | 2014-02-06 | 2020-08-20 | Янссен Сайенсиз Айрлэнд Юси | Производные сульфамоилпирроламида и их применение в качестве медикаментов для лечения гепатита b |
CN107847762A (zh) | 2015-03-19 | 2018-03-27 | 诺维拉治疗公司 | 氮杂环辛烷和氮杂环壬烷衍生物以及治疗乙型肝炎感染的方法 |
US10875876B2 (en) | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
AR106192A1 (es) | 2015-09-29 | 2017-12-20 | Novira Therapeutics Inc | Formas cristalinas de un agente antiviral contra la hepatitis b |
EP3848026A1 (en) | 2016-04-15 | 2021-07-14 | Novira Therapeutics Inc. | Combinations and methods comprising a capsid assembly inhibitor |
EA202092171A1 (ru) | 2018-03-14 | 2020-12-01 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Схема дозирования модулятора сборки капсида |
CN113454077A (zh) | 2019-02-22 | 2021-09-28 | 爱尔兰詹森科学公司 | 用于治疗hbv感染或hbv诱发的疾病的酰胺衍生物 |
KR20220005549A (ko) | 2019-05-06 | 2022-01-13 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | Hbv 감염 또는 hbv-유도성 질환의 치료에 유용한 아미드 유도체 |
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US4505915A (en) * | 1979-05-29 | 1985-03-19 | Merck & Co., Inc. | 6-N-Heterocyclyl penicillins |
US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
US5889006A (en) * | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
WO1998001425A1 (en) * | 1996-07-10 | 1998-01-15 | Schering Corporation | 1,4-di-sustituted piperidines as muscarinic antagonists |
US5952349A (en) * | 1996-07-10 | 1999-09-14 | Schering Corporation | Muscarinic antagonists for treating memory loss |
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PT1076055E (pt) * | 1998-04-28 | 2005-02-28 | Dainippon Pharmaceutical Co | Derivados de 1-[ (1-substituido-4-piperidinil)-metil]-4-piperidina, processo para a sua preparacao, composicoes medicinais que os contem e intermediarios destes compostos |
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WO2000035877A1 (en) * | 1998-12-18 | 2000-06-22 | Du Pont Pharmaceuticals Company | Heterocyclic piperidines as modulators of chemokine receptor activity |
US6387930B1 (en) * | 1999-05-04 | 2002-05-14 | Schering Corporation | Piperidine derivatives useful as CCR5 antagonists |
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- 2003-09-12 EP EP03798620A patent/EP1546130B1/en not_active Expired - Lifetime
- 2003-09-12 US US10/528,477 patent/US20060040984A1/en not_active Abandoned
- 2003-09-12 PL PL03376119A patent/PL376119A1/xx not_active Application Discontinuation
- 2003-09-12 AT AT03798620T patent/ATE368656T1/de not_active IP Right Cessation
- 2003-09-12 EP EP07010143A patent/EP1816123A1/en not_active Withdrawn
- 2003-09-12 ES ES03798620T patent/ES2289354T3/es not_active Expired - Lifetime
- 2003-09-12 AU AU2003259004A patent/AU2003259004B2/en not_active Ceased
- 2003-09-12 MX MXPA05003007A patent/MXPA05003007A/es unknown
- 2003-09-12 WO PCT/SE2003/001425 patent/WO2004029041A1/en active IP Right Grant
- 2003-09-12 BR BR0314688-0A patent/BR0314688A/pt not_active IP Right Cessation
- 2003-09-12 JP JP2004539695A patent/JP2006503066A/ja active Pending
- 2003-09-12 NZ NZ538527A patent/NZ538527A/en unknown
- 2003-09-12 RU RU2005105053/04A patent/RU2005105053A/ru not_active Application Discontinuation
-
2005
- 2005-03-18 ZA ZA200502341A patent/ZA200502341B/en unknown
- 2005-04-20 IS IS7813A patent/IS7813A/is unknown
- 2005-04-22 NO NO20051965A patent/NO20051965L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20050052511A (ko) | 2005-06-02 |
AU2003259004B2 (en) | 2007-02-08 |
NZ538527A (en) | 2006-10-27 |
JP2006503066A (ja) | 2006-01-26 |
MXPA05003007A (es) | 2005-06-22 |
DE60315323T2 (de) | 2008-04-17 |
ES2289354T3 (es) | 2008-02-01 |
EP1546130A1 (en) | 2005-06-29 |
DE60315323D1 (de) | 2007-09-13 |
ATE368656T1 (de) | 2007-08-15 |
CA2497280A1 (en) | 2004-04-08 |
US20060040984A1 (en) | 2006-02-23 |
BR0314688A (pt) | 2005-08-02 |
EP1546130B1 (en) | 2007-08-01 |
WO2004029041A1 (en) | 2004-04-08 |
SE0202838D0 (sv) | 2002-09-24 |
NO20051965L (no) | 2005-06-23 |
CN1684952A (zh) | 2005-10-19 |
IS7813A (is) | 2005-04-20 |
EP1816123A1 (en) | 2007-08-08 |
RU2005105053A (ru) | 2005-12-10 |
PL376119A1 (en) | 2005-12-12 |
AU2003259004A1 (en) | 2004-04-19 |
NO20051965D0 (no) | 2005-04-22 |
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