ZA200409888B - Arylakyl indoles having sertonin receptor affinity useful as therapeutic agents process for their preparation and pharmaceutical compositions containing them - Google Patents
Arylakyl indoles having sertonin receptor affinity useful as therapeutic agents process for their preparation and pharmaceutical compositions containing them Download PDFInfo
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- ZA200409888B ZA200409888B ZA200409888A ZA200409888A ZA200409888B ZA 200409888 B ZA200409888 B ZA 200409888B ZA 200409888 A ZA200409888 A ZA 200409888A ZA 200409888 A ZA200409888 A ZA 200409888A ZA 200409888 B ZA200409888 B ZA 200409888B
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- ZA
- South Africa
- Prior art keywords
- isoindolo
- compound
- heteroatoms
- derivatives
- group
- Prior art date
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- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims description 2
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN476CH2002 | 2002-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200409888B true ZA200409888B (en) | 2006-07-26 |
Family
ID=29798511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200409888A ZA200409888B (en) | 2002-06-21 | 2004-12-07 | Arylakyl indoles having sertonin receptor affinity useful as therapeutic agents process for their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7297711B2 (pt) |
| EP (1) | EP1537113B9 (pt) |
| JP (1) | JP4455992B2 (pt) |
| CN (1) | CN1662538A (pt) |
| AT (1) | ATE444965T1 (pt) |
| AU (1) | AU2003249584B9 (pt) |
| BR (1) | BR0312175A (pt) |
| CA (1) | CA2490115C (pt) |
| DE (1) | DE60329607D1 (pt) |
| DK (1) | DK1537113T5 (pt) |
| ES (1) | ES2336664T3 (pt) |
| HK (1) | HK1074842A1 (pt) |
| MX (1) | MXPA04012834A (pt) |
| NZ (1) | NZ537772A (pt) |
| RU (1) | RU2320663C2 (pt) |
| WO (1) | WO2004000845A1 (pt) |
| ZA (1) | ZA200409888B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7781476B2 (en) * | 2002-12-18 | 2010-08-24 | Suven Life Sciences Limited | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
| CA2552106C (en) | 2004-01-02 | 2011-10-11 | Suven Life Sciences Limited | Novel indeno[2,1a]indenes and isoindol[2,1-a]indoles |
| US9125900B2 (en) * | 2005-09-14 | 2015-09-08 | University Of The Witwatersrand, Johannesburg | Pharmaceutical composition |
| JP4950490B2 (ja) * | 2005-12-28 | 2012-06-13 | 株式会社東芝 | 不揮発性スイッチング素子およびその製造方法ならびに不揮発性スイッチング素子を有する集積回路 |
| JP2011529477A (ja) * | 2008-07-30 | 2011-12-08 | フエルレル インターナショナル，ソシエダッド アノニマ | １，６−ジヒドロ−２ｈ−３−オキサ−６−アザ−ａｓ−インダセン化合物 |
| CN110590748A (zh) * | 2019-10-03 | 2019-12-20 | 黄泳华 | 芳香基氨基苄基哌嗪氮氧化物及其组合物与用途 |
| KR20220131520A (ko) | 2019-12-26 | 2022-09-28 | 길가메쉬 파마슈티컬스, 인코포레이티드 | 아릴시클로헥실아민 유도체 및 정신장애 치료에서의 이의 용도 |
| MX2022010082A (es) | 2020-02-18 | 2022-11-14 | Gilgamesh Pharmaceuticals Inc | Triptaminas especificas para usarse en el tratamiento de trastornos de estado de animo. |
| EP4153564A4 (en) | 2020-05-19 | 2024-06-19 | Cybin IRL Limited | DEUTERATED TRYPTAMINE DERIVATIVES AND METHODS OF USE |
| AU2021337466A1 (en) | 2020-09-01 | 2023-03-30 | Enveric Biosciences Canada Inc. | Halogenated psilocybin derivatives and methods of using |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA795239B (en) | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
| ZA815541B (en) | 1980-08-12 | 1983-03-30 | Glaxo Group Ltd | Heterocyclic compounds |
| GB8600397D0 (en) | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8719167D0 (en) | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
| GB8724912D0 (en) | 1987-10-23 | 1987-11-25 | Wellcome Found | Indole derivatives |
| GB8819024D0 (en) | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
| IL96891A0 (en) | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| CA2042295A1 (fr) | 1990-05-15 | 1991-11-16 | Jacques Chauveau | Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant |
| HU219974B (hu) | 1990-06-07 | 2001-10-28 | Astrazeneca Ab, | Heterociklusos csoporttal helyettesített indolszármazék, előállítása és a vegyületet hatóanyagként tartalmazó gyógyszerkészítmények |
| SK278998B6 (sk) | 1991-02-01 | 1998-05-06 | Merck Sharp & Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu, spôsob i |
| GB9113802D0 (en) | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
| US5206382A (en) * | 1991-06-27 | 1993-04-27 | Fidia Georgetown Institute For The Neurosciences | Indole derivatives, pharmaceutical compositions and methods of treating neurological and psychiatric disorders |
| GB9210400D0 (en) | 1992-05-15 | 1992-07-01 | Merck Sharp & Dohme | Therapeutic agents |
| KR940007001A (ko) | 1992-09-16 | 1994-04-26 | 최승주 | 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제 |
| FR2821843B1 (fr) * | 2001-03-12 | 2003-05-09 | Servier Lab | Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2003
- 2003-06-19 CA CA002490115A patent/CA2490115C/en not_active Expired - Fee Related
- 2003-06-19 DE DE60329607T patent/DE60329607D1/de not_active Expired - Lifetime
- 2003-06-19 AT AT03760859T patent/ATE444965T1/de active
- 2003-06-19 AU AU2003249584A patent/AU2003249584B9/en not_active Ceased
- 2003-06-19 ES ES03760859T patent/ES2336664T3/es not_active Expired - Lifetime
- 2003-06-19 CN CN038145979A patent/CN1662538A/zh active Pending
- 2003-06-19 WO PCT/IN2003/000224 patent/WO2004000845A1/en active Application Filing
- 2003-06-19 DK DK03760859.3T patent/DK1537113T5/da active
- 2003-06-19 BR BR0312175-5A patent/BR0312175A/pt not_active IP Right Cessation
- 2003-06-19 NZ NZ537772A patent/NZ537772A/en not_active IP Right Cessation
- 2003-06-19 US US10/518,624 patent/US7297711B2/en not_active Expired - Lifetime
- 2003-06-19 RU RU2005101343/04A patent/RU2320663C2/ru not_active IP Right Cessation
- 2003-06-19 EP EP03760859A patent/EP1537113B9/en not_active Expired - Lifetime
- 2003-06-19 JP JP2004515420A patent/JP4455992B2/ja not_active Expired - Fee Related
- 2003-06-19 MX MXPA04012834A patent/MXPA04012834A/es active IP Right Grant
-
2004
- 2004-12-07 ZA ZA200409888A patent/ZA200409888B/en unknown
-
2005
- 2005-10-06 HK HK05108863.2A patent/HK1074842A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2490115A1 (en) | 2003-12-31 |
| JP4455992B2 (ja) | 2010-04-21 |
| ATE444965T1 (de) | 2009-10-15 |
| EP1537113A1 (en) | 2005-06-08 |
| CN1662538A (zh) | 2005-08-31 |
| DK1537113T3 (da) | 2010-02-15 |
| CA2490115C (en) | 2009-09-01 |
| DK1537113T5 (da) | 2011-01-10 |
| US7297711B2 (en) | 2007-11-20 |
| AU2003249584B2 (en) | 2007-10-25 |
| WO2004000845A1 (en) | 2003-12-31 |
| BR0312175A (pt) | 2005-04-05 |
| NZ537772A (en) | 2007-05-31 |
| DE60329607D1 (de) | 2009-11-19 |
| RU2005101343A (ru) | 2005-11-20 |
| MXPA04012834A (es) | 2005-04-25 |
| AU2003249584A1 (en) | 2004-01-06 |
| HK1074842A1 (en) | 2005-11-25 |
| US20050203103A1 (en) | 2005-09-15 |
| AU2003249584B9 (en) | 2008-05-15 |
| ES2336664T3 (es) | 2010-04-15 |
| EP1537113B1 (en) | 2009-10-07 |
| JP2006501175A (ja) | 2006-01-12 |
| EP1537113B9 (en) | 2010-05-26 |
| RU2320663C2 (ru) | 2008-03-27 |
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