DK1537113T3 - Arylalkylindoler med serotoninreceptoraffinitet anvendelige som terapeutiske midler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse - Google Patents

Arylalkylindoler med serotoninreceptoraffinitet anvendelige som terapeutiske midler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Info

Publication number: DK1537113T3
Authority: DK; Denmark
Prior art keywords: pharmaceutically acceptable; compositions containing; preparation; pharmaceutical compositions; therapeutic agents
Prior art date: 2002-06-21

Application number

DK03760859.3T

Other languages

English (en)

Other versions

DK1537113T5 (da

Inventor

Srinivasa Reddy Battula

Venkata Satya Veerabhadra Vadlamudi Rao

Venkateswarlu Jasti

Venkata Satya Nirogi Ramakrishna

Rama Sastri Kambhampati

Original Assignee

Suven Life Sciences Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-21

Filing date

2003-06-19

Publication date

2010-02-15

2003-06-19 Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd

2010-02-15 Publication of DK1537113T3 publication Critical patent/DK1537113T3/da

2011-01-10 Application granted granted Critical

2011-01-10 Publication of DK1537113T5 publication Critical patent/DK1537113T5/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Psychology (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Obesity (AREA)
Addiction (AREA)
Child & Adolescent Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Reproductive Health (AREA)
Otolaryngology (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK03760859.3T 2002-06-21 2003-06-19 Arylalkylindoler med serotoninreceptoraffinitet anvendelige som terapeutiske midler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse DK1537113T5 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN476CH2002		2002-06-21
PCT/IN2003/000224 WO2004000845A1 (en)	2002-06-21	2003-06-19	Arylalkyl indoles having sertonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them

Publications (2)

Publication Number	Publication Date
DK1537113T3 true DK1537113T3 (da)	2010-02-15
DK1537113T5 DK1537113T5 (da)	2011-01-10

Family

ID=29798511

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03760859.3T DK1537113T5 (da)	2002-06-21	2003-06-19	Arylalkylindoler med serotoninreceptoraffinitet anvendelige som terapeutiske midler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Country Status (17)

Country	Link
US (1)	US7297711B2 (da)
EP (1)	EP1537113B9 (da)
JP (1)	JP4455992B2 (da)
CN (1)	CN1662538A (da)
AT (1)	ATE444965T1 (da)
AU (1)	AU2003249584B9 (da)
BR (1)	BR0312175A (da)
CA (1)	CA2490115C (da)
DE (1)	DE60329607D1 (da)
DK (1)	DK1537113T5 (da)
ES (1)	ES2336664T3 (da)
HK (1)	HK1074842A1 (da)
MX (1)	MXPA04012834A (da)
NZ (1)	NZ537772A (da)
RU (1)	RU2320663C2 (da)
WO (1)	WO2004000845A1 (da)
ZA (1)	ZA200409888B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003292510B2 (en) *	2002-12-18	2009-04-23	Suven Life Sciences Limited	Tetracyclic 3-substituted indoles having serotonin receptor affinity
WO2005066184A1 (en) *	2004-01-02	2005-07-21	Suven Life Sciences Limited	Novel indeno[2,1a]indenes and isoindol[2,1-a]indoles
EP1937255A4 (en) *	2005-09-14	2013-06-26	Univ Witwatersrand Jhb	PHARMACEUTICAL COMPOSITION
JP4950490B2 (ja) *	2005-12-28	2012-06-13	株式会社東芝	不揮発性スイッチング素子およびその製造方法ならびに不揮発性スイッチング素子を有する集積回路
MX2011001062A (es) *	2008-07-30	2011-03-24	Ferrer Int	Compuestos de 1,6-dihidro-2h-3-oxa-6-aza-as-indaceno.
CN110590748A (zh) *	2019-10-03	2019-12-20	黄泳华	芳香基氨基苄基哌嗪氮氧化物及其组合物与用途
JP2023508469A (ja)	2019-12-26	2023-03-02	ギルガメッシュ・ファーマシューティカルズ・インコーポレイテッド	アリールシクロヘキシルアミン誘導体及び精神障害の処置におけるそれらの使用
CN115135320B (zh)	2020-02-18	2023-08-29	吉尔伽美什制药公司	用于治疗情绪障碍的特定色胺
MX2022014605A (es)	2020-05-19	2022-12-16	Cybin Irl Ltd	Derivados de triptamina deuterada y metodos de uso.
JP2023539949A (ja)	2020-09-01	2023-09-20	エンベリックバイオサイエンシズカナダインコーポレイテッド	ハロゲン化シロシビン誘導体および使用方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA795239B (en)	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
ZA815541B (en) *	1980-08-12	1983-03-30	Glaxo Group Ltd	Heterocyclic compounds
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
GB8719167D0 (en)	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
GB8724912D0 (en)	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en)	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
IL96891A0 (en)	1990-01-17	1992-03-29	Merck Sharp & Dohme	Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr)	1990-05-15	1991-11-16	Jacques Chauveau	Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
SI21560B (sl)	1990-06-07	2005-04-30	Astrazeneca Ab	3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti
CZ283018B6 (cs)	1991-02-01	1997-12-17	Merck Sharp And Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
GB9113802D0 (en)	1991-06-26	1991-08-14	Smithkline Beecham Plc	Medicaments
US5206382A (en) *	1991-06-27	1993-04-27	Fidia Georgetown Institute For The Neurosciences	Indole derivatives, pharmaceutical compositions and methods of treating neurological and psychiatric disorders
GB9210400D0 (en)	1992-05-15	1992-07-01	Merck Sharp & Dohme	Therapeutic agents
KR940007001A (ko)	1992-09-16	1994-04-26	최승주	새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제
FR2821843B1 (fr) *	2001-03-12	2003-05-09	Servier Lab	Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

2003
- 2003-06-19 AT AT03760859T patent/ATE444965T1/de active
- 2003-06-19 US US10/518,624 patent/US7297711B2/en not_active Expired - Lifetime
- 2003-06-19 CN CN038145979A patent/CN1662538A/zh active Pending
- 2003-06-19 MX MXPA04012834A patent/MXPA04012834A/es active IP Right Grant
- 2003-06-19 ES ES03760859T patent/ES2336664T3/es not_active Expired - Lifetime
- 2003-06-19 JP JP2004515420A patent/JP4455992B2/ja not_active Expired - Fee Related
- 2003-06-19 WO PCT/IN2003/000224 patent/WO2004000845A1/en active Application Filing
- 2003-06-19 EP EP03760859A patent/EP1537113B9/en not_active Expired - Lifetime
- 2003-06-19 DE DE60329607T patent/DE60329607D1/de not_active Expired - Lifetime
- 2003-06-19 BR BR0312175-5A patent/BR0312175A/pt not_active IP Right Cessation
- 2003-06-19 AU AU2003249584A patent/AU2003249584B9/en not_active Ceased
- 2003-06-19 DK DK03760859.3T patent/DK1537113T5/da active
- 2003-06-19 CA CA002490115A patent/CA2490115C/en not_active Expired - Fee Related
- 2003-06-19 NZ NZ537772A patent/NZ537772A/en not_active IP Right Cessation
- 2003-06-19 RU RU2005101343/04A patent/RU2320663C2/ru not_active IP Right Cessation
2004
- 2004-12-07 ZA ZA200409888A patent/ZA200409888B/en unknown
2005
- 2005-10-06 HK HK05108863.2A patent/HK1074842A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE60329607D1 (de)	2009-11-19
CA2490115C (en)	2009-09-01
EP1537113B1 (en)	2009-10-07
RU2005101343A (ru)	2005-11-20
ZA200409888B (en)	2006-07-26
US7297711B2 (en)	2007-11-20
RU2320663C2 (ru)	2008-03-27
HK1074842A1 (en)	2005-11-25
DK1537113T5 (da)	2011-01-10
CN1662538A (zh)	2005-08-31
EP1537113B9 (en)	2010-05-26
EP1537113A1 (en)	2005-06-08
MXPA04012834A (es)	2005-04-25
ATE444965T1 (de)	2009-10-15
BR0312175A (pt)	2005-04-05
CA2490115A1 (en)	2003-12-31
AU2003249584B9 (en)	2008-05-15
WO2004000845A1 (en)	2003-12-31
NZ537772A (en)	2007-05-31
JP4455992B2 (ja)	2010-04-21
AU2003249584B2 (en)	2007-10-25
US20050203103A1 (en)	2005-09-15
JP2006501175A (ja)	2006-01-12
AU2003249584A1 (en)	2004-01-06
ES2336664T3 (es)	2010-04-15

Publication	Publication Date	Title
HK1074842A1 (en)	2005-11-25	Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
WO2004048330A8 (en)	2005-10-27	N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them
HK1074843A1 (en)	2005-11-25	Tetracyclic arylsulfonyl indoles having serotonin receptor affinity
MXPA05011710A (es)	2006-01-23	Derivados de pirimidina con actividad de crf.
MY141559A (en)	2010-05-14	Triazole derivatives as tachykinin receptor antagonists
BR0315317A (pt)	2005-09-06	4-piperazinil benzenossulfonil indóis com afinidade para o receptor de 5-ht6
GEP20094727B (en)	2009-07-10	Oxyindole derivatives as 5ht4 receptor agonists
MXPA03011638A (es)	2004-04-02	Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
NO20061981L (no)	2006-07-03	Arylindenopyridiner og arylindenopyridiner og deres anvendelse som adenosin A2A reseptoragonist
HK1070054A1 (en)	2005-06-10	Arylsulfonyl derivatives with5-ht6 receptor affinity
DE602004005960D1 (de)	2007-05-31	Heteroaryl-substituierte pyrrolä2, 3- büpyridin-derivate als crf-rezeptor-antagonisten
MXPA04005426A (es)	2004-10-11	Derivados de pirazol de anillos fuisionados.
HK1074630A1 (en)	2005-11-18	Novel tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
NO20080671L (no)	2008-03-04	Bisykliske piperaziner som metabotrofiske glutamatreseptorantagonister
MXPA05011841A (es)	2006-01-26	Metil-indoles y metil-pirrolopiridinas como agonistas adrenergicos de alfa-1.
RS20050426A (en)	2008-04-04	Substituted aralkyl derivatives
ECSP034870A (es)	2004-01-28	Nuevos derivados de indol con afinidad por el receptor 5-ht6