ZA200409888B - Arylakyl indoles having sertonin receptor affinity useful as therapeutic agents process for their preparation and pharmaceutical compositions containing them - Google Patents
Arylakyl indoles having sertonin receptor affinity useful as therapeutic agents process for their preparation and pharmaceutical compositions containing them Download PDFInfo
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- ZA200409888B ZA200409888B ZA200409888A ZA200409888A ZA200409888B ZA 200409888 B ZA200409888 B ZA 200409888B ZA 200409888 A ZA200409888 A ZA 200409888A ZA 200409888 A ZA200409888 A ZA 200409888A ZA 200409888 B ZA200409888 B ZA 200409888B
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- ZA
- South Africa
- Prior art keywords
- isoindolo
- compound
- heteroatoms
- derivatives
- group
- Prior art date
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- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims description 2
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN476CH2002 | 2002-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200409888B true ZA200409888B (en) | 2006-07-26 |
Family
ID=29798511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200409888A ZA200409888B (en) | 2002-06-21 | 2004-12-07 | Arylakyl indoles having sertonin receptor affinity useful as therapeutic agents process for their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7297711B2 (de) |
| EP (1) | EP1537113B9 (de) |
| JP (1) | JP4455992B2 (de) |
| CN (1) | CN1662538A (de) |
| AT (1) | ATE444965T1 (de) |
| AU (1) | AU2003249584B9 (de) |
| BR (1) | BR0312175A (de) |
| CA (1) | CA2490115C (de) |
| DE (1) | DE60329607D1 (de) |
| DK (1) | DK1537113T5 (de) |
| ES (1) | ES2336664T3 (de) |
| HK (1) | HK1074842A1 (de) |
| MX (1) | MXPA04012834A (de) |
| NZ (1) | NZ537772A (de) |
| RU (1) | RU2320663C2 (de) |
| WO (1) | WO2004000845A1 (de) |
| ZA (1) | ZA200409888B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003292510B2 (en) * | 2002-12-18 | 2009-04-23 | Suven Life Sciences Limited | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
| WO2005066184A1 (en) * | 2004-01-02 | 2005-07-21 | Suven Life Sciences Limited | Novel indeno[2,1a]indenes and isoindol[2,1-a]indoles |
| EP1937255A4 (de) * | 2005-09-14 | 2013-06-26 | Univ Witwatersrand Jhb | Pharmazeutische zusammensetzung |
| JP4950490B2 (ja) * | 2005-12-28 | 2012-06-13 | 株式会社東芝 | 不揮発性スイッチング素子およびその製造方法ならびに不揮発性スイッチング素子を有する集積回路 |
| MX2011001062A (es) * | 2008-07-30 | 2011-03-24 | Ferrer Int | Compuestos de 1,6-dihidro-2h-3-oxa-6-aza-as-indaceno. |
| CN110590748A (zh) * | 2019-10-03 | 2019-12-20 | 黄泳华 | 芳香基氨基苄基哌嗪氮氧化物及其组合物与用途 |
| JP2023508469A (ja) | 2019-12-26 | 2023-03-02 | ギルガメッシュ・ファーマシューティカルズ・インコーポレイテッド | アリールシクロヘキシルアミン誘導体及び精神障害の処置におけるそれらの使用 |
| CN115135320B (zh) | 2020-02-18 | 2023-08-29 | 吉尔伽美什制药公司 | 用于治疗情绪障碍的特定色胺 |
| MX2022014605A (es) | 2020-05-19 | 2022-12-16 | Cybin Irl Ltd | Derivados de triptamina deuterada y metodos de uso. |
| JP2023539949A (ja) | 2020-09-01 | 2023-09-20 | エンベリック バイオサイエンシズ カナダ インコーポレイテッド | ハロゲン化シロシビン誘導体および使用方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA795239B (en) | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
| ZA815541B (en) * | 1980-08-12 | 1983-03-30 | Glaxo Group Ltd | Heterocyclic compounds |
| GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8719167D0 (en) | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
| GB8724912D0 (en) | 1987-10-23 | 1987-11-25 | Wellcome Found | Indole derivatives |
| GB8819024D0 (en) | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
| IL96891A0 (en) | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| CA2042295A1 (fr) | 1990-05-15 | 1991-11-16 | Jacques Chauveau | Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant |
| SI21560B (sl) | 1990-06-07 | 2005-04-30 | Astrazeneca Ab | 3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti |
| CZ283018B6 (cs) | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
| GB9113802D0 (en) | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
| US5206382A (en) * | 1991-06-27 | 1993-04-27 | Fidia Georgetown Institute For The Neurosciences | Indole derivatives, pharmaceutical compositions and methods of treating neurological and psychiatric disorders |
| GB9210400D0 (en) | 1992-05-15 | 1992-07-01 | Merck Sharp & Dohme | Therapeutic agents |
| KR940007001A (ko) | 1992-09-16 | 1994-04-26 | 최승주 | 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제 |
| FR2821843B1 (fr) * | 2001-03-12 | 2003-05-09 | Servier Lab | Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2003
- 2003-06-19 AT AT03760859T patent/ATE444965T1/de active
- 2003-06-19 US US10/518,624 patent/US7297711B2/en not_active Expired - Lifetime
- 2003-06-19 CN CN038145979A patent/CN1662538A/zh active Pending
- 2003-06-19 MX MXPA04012834A patent/MXPA04012834A/es active IP Right Grant
- 2003-06-19 ES ES03760859T patent/ES2336664T3/es not_active Expired - Lifetime
- 2003-06-19 JP JP2004515420A patent/JP4455992B2/ja not_active Expired - Fee Related
- 2003-06-19 WO PCT/IN2003/000224 patent/WO2004000845A1/en active Application Filing
- 2003-06-19 EP EP03760859A patent/EP1537113B9/de not_active Expired - Lifetime
- 2003-06-19 DE DE60329607T patent/DE60329607D1/de not_active Expired - Lifetime
- 2003-06-19 BR BR0312175-5A patent/BR0312175A/pt not_active IP Right Cessation
- 2003-06-19 AU AU2003249584A patent/AU2003249584B9/en not_active Ceased
- 2003-06-19 DK DK03760859.3T patent/DK1537113T5/da active
- 2003-06-19 CA CA002490115A patent/CA2490115C/en not_active Expired - Fee Related
- 2003-06-19 NZ NZ537772A patent/NZ537772A/en not_active IP Right Cessation
- 2003-06-19 RU RU2005101343/04A patent/RU2320663C2/ru not_active IP Right Cessation
-
2004
- 2004-12-07 ZA ZA200409888A patent/ZA200409888B/en unknown
-
2005
- 2005-10-06 HK HK05108863.2A patent/HK1074842A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60329607D1 (de) | 2009-11-19 |
| CA2490115C (en) | 2009-09-01 |
| EP1537113B1 (de) | 2009-10-07 |
| RU2005101343A (ru) | 2005-11-20 |
| DK1537113T3 (da) | 2010-02-15 |
| US7297711B2 (en) | 2007-11-20 |
| RU2320663C2 (ru) | 2008-03-27 |
| HK1074842A1 (en) | 2005-11-25 |
| DK1537113T5 (da) | 2011-01-10 |
| CN1662538A (zh) | 2005-08-31 |
| EP1537113B9 (de) | 2010-05-26 |
| EP1537113A1 (de) | 2005-06-08 |
| MXPA04012834A (es) | 2005-04-25 |
| ATE444965T1 (de) | 2009-10-15 |
| BR0312175A (pt) | 2005-04-05 |
| CA2490115A1 (en) | 2003-12-31 |
| AU2003249584B9 (en) | 2008-05-15 |
| WO2004000845A1 (en) | 2003-12-31 |
| NZ537772A (en) | 2007-05-31 |
| JP4455992B2 (ja) | 2010-04-21 |
| AU2003249584B2 (en) | 2007-10-25 |
| US20050203103A1 (en) | 2005-09-15 |
| JP2006501175A (ja) | 2006-01-12 |
| AU2003249584A1 (en) | 2004-01-06 |
| ES2336664T3 (es) | 2010-04-15 |
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