YU49486B - Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl) methylpiperidine - Google Patents

Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl) methylpiperidine

Info

Publication number
YU49486B
YU49486B YU66096A YU66096A YU49486B YU 49486 B YU49486 B YU 49486B YU 66096 A YU66096 A YU 66096A YU 66096 A YU66096 A YU 66096A YU 49486 B YU49486 B YU 49486B
Authority
YU
Yugoslavia
Prior art keywords
indanon
methylpiperidine
dimethoxy
intermediates
benzyl
Prior art date
Application number
YU66096A
Other languages
Serbo-Croatian (sh)
Other versions
YU66096A (en
Inventor
Keith M. Devries
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU66096A publication Critical patent/YU66096A/en
Publication of YU49486B publication Critical patent/YU49486B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Jedinjenja formule naznačeno time, što R1 je R2 O(C=O)-, R2 je (C1-C4)alkil. Prijava sadrži još 4 nezavisna i 11 zavisnih patentnih zahteva.Compounds of formula wherein R 1 is R 2 O (C = O) -, R 2 is (C 1 -C 4) alkyl. The application contains 4 more independent and 11 dependent patent claims.

YU66096A 1995-12-15 1996-12-11 Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl) methylpiperidine YU49486B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US875395P 1995-12-15 1995-12-15

Publications (2)

Publication Number Publication Date
YU66096A YU66096A (en) 1999-11-22
YU49486B true YU49486B (en) 2006-08-17

Family

ID=21733469

Family Applications (1)

Application Number Title Priority Date Filing Date
YU66096A YU49486B (en) 1995-12-15 1996-12-11 Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl) methylpiperidine

Country Status (33)

Country Link
EP (1) EP0883607A1 (en)
JP (1) JP3066083B2 (en)
KR (1) KR20000064387A (en)
AP (1) AP708A (en)
AR (1) AR004368A1 (en)
AU (1) AU716462B2 (en)
BG (1) BG102525A (en)
BR (1) BR9612018A (en)
CA (1) CA2237647A1 (en)
CO (1) CO4750831A1 (en)
CZ (1) CZ180898A3 (en)
DZ (1) DZ2141A1 (en)
GT (1) GT199600092A (en)
HN (1) HN1996000065A (en)
HR (1) HRP960592A2 (en)
HU (1) HUP9904275A3 (en)
IL (3) IL136421A0 (en)
IS (1) IS4752A (en)
MA (1) MA24032A1 (en)
NO (1) NO982712L (en)
NZ (1) NZ318843A (en)
OA (1) OA10694A (en)
PE (1) PE25698A1 (en)
PL (1) PL197306B1 (en)
RO (1) RO121382B1 (en)
RU (1) RU2160731C2 (en)
SK (1) SK75498A3 (en)
TN (1) TNSN96153A1 (en)
TW (1) TW414787B (en)
UY (1) UY24401A1 (en)
WO (1) WO1997022584A1 (en)
YU (1) YU49486B (en)
ZA (1) ZA9610533B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999036405A1 (en) 1998-01-16 1999-07-22 Eisai Co., Ltd. Process for production of donepezil derivative
IL125809A (en) * 1998-08-17 2005-08-31 Finetech Lab Ltd Process and intermediates for production of donepezil and related compounds
US7148354B2 (en) * 2002-07-24 2006-12-12 Dr. Reddy's Laboratories Limited Process for preparation of donepezil
IL150982A (en) 2002-07-30 2007-02-11 Ori Lerman Process for the preparation of donepezil
IL151253A0 (en) * 2002-08-14 2003-04-10 Finetech Lab Ltd Process for production of highly pure donepezil hydrochloride
US6953856B2 (en) 2003-02-12 2005-10-11 Usv, Limited Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI)
US6649765B1 (en) 2003-02-12 2003-11-18 Usv Limited, Bsd Marg. Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL)
EP1608371A1 (en) * 2003-03-21 2005-12-28 Ranbaxy Laboratories, Ltd. Process for the preparation of donepezil and derivatives thereof
WO2004099142A1 (en) * 2003-05-05 2004-11-18 Ranbaxy Laboratories Limited Hydrobromide salt of benzyl-piperidylmethyl-indanone and its polymorphs
AU2003247158A1 (en) 2003-07-01 2005-01-21 Hetero Drugs Limited Preparation of intermediates for acetyl cholinesterase inhibitors
CN1280273C (en) 2003-11-05 2006-10-18 天津和美生物技术有限公司 Synthesis of donepizin and its derivative
JP2008514691A (en) 2004-09-29 2008-05-08 ケマジス リミティド Use of purified donepezil maleate to produce pharmaceutically pure amorphous donepezil hydrochloride
CN100436416C (en) * 2005-07-29 2008-11-26 西南合成制药股份有限公司 Novel donepezil synthesis process
GB0515803D0 (en) 2005-07-30 2005-09-07 Pliva Hrvatska D O O Intermediate compounds
AR057910A1 (en) 2005-11-18 2007-12-26 Synthon Bv PROCESS TO PREPARE DONEPEZILO
ES2354737T3 (en) 2006-01-04 2011-03-17 Cipla Limited PROCEDURE AND INTERMEDIATE PRODUCT FOR THE PREPARATION OF DONEPEZYLO.
BRPI0720211A2 (en) * 2006-12-11 2013-12-24 Reviva Pharmaceuticals Inc INDANONE DERIVATIVE, COMPOSITION, AND, USE OF A COMPOSITION
WO2013078608A1 (en) * 2011-11-29 2013-06-06 Ziqiang Gu Donepezil pamoate and methods of making and using the same
AU2014307803A1 (en) 2013-08-16 2016-03-10 Universiteit Maastricht Treatment of cognitive impairment with PDE4 inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (en) * 1987-06-22 1996-02-26 Eisai Co Ltd Process for the preparation of a medicament useful as a piperidine derivative or its pharmaceutical salt
FR2642069B1 (en) * 1989-01-20 1991-04-12 Rhone Poulenc Sante NOVEL BENZOPYRAN DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE4439822A1 (en) * 1994-11-08 1996-08-29 Bayer Ag Process for the preparation of benzyl-piperidylmethyl-indanones

Also Published As

Publication number Publication date
PL327512A1 (en) 1998-12-21
AU716462B2 (en) 2000-02-24
DZ2141A1 (en) 2002-07-23
PL197306B1 (en) 2008-03-31
RU2160731C2 (en) 2000-12-20
MX9804820A (en) 1998-10-31
NO982712D0 (en) 1998-06-12
OA10694A (en) 2001-05-04
EP0883607A1 (en) 1998-12-16
PE25698A1 (en) 1998-05-21
AP708A (en) 1998-12-04
GT199600092A (en) 1998-05-12
NO982712L (en) 1998-06-12
RO121382B1 (en) 2007-04-30
AR004368A1 (en) 1998-11-04
HRP960592A2 (en) 1998-06-30
ZA9610533B (en) 1998-06-15
AU7092596A (en) 1997-07-14
JPH11500756A (en) 1999-01-19
NZ318843A (en) 2000-01-28
BR9612018A (en) 1999-02-17
TW414787B (en) 2000-12-11
HUP9904275A2 (en) 2000-05-28
SK75498A3 (en) 1999-08-06
UY24401A1 (en) 1997-06-09
MA24032A1 (en) 1997-07-01
YU66096A (en) 1999-11-22
BG102525A (en) 1999-05-31
KR20000064387A (en) 2000-11-06
CA2237647A1 (en) 1997-06-26
TNSN96153A1 (en) 2005-03-15
AP9600892A0 (en) 1997-01-31
IL124452A0 (en) 1998-12-06
IS4752A (en) 1998-05-22
WO1997022584A1 (en) 1997-06-26
HN1996000065A (en) 1997-06-26
IL136420A0 (en) 2001-06-14
CZ180898A3 (en) 1999-05-12
HUP9904275A3 (en) 2001-05-28
JP3066083B2 (en) 2000-07-17
CO4750831A1 (en) 1999-03-31
IL136421A0 (en) 2001-06-14

Similar Documents

Publication Publication Date Title
YU49486B (en) Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl) methylpiperidine
DE69709938T2 (en) N-BENZYLPIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES
NO996269L (en) Quinoline-indole antimicrobial agents, as well as the use and mixtures thereof
AU6613896A (en) Chemical compounds
NO20051600L (en) 1,4-disubstituted piperidine derivatives and their use as 11-betaHSD1 inhibitors
NO20004121L (en) New compounds and their use as positive AMPA receptor modulators
EA199800141A1 (en) HETEROCYCLIC COMPOUNDS
DK51986A (en) HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE AS INSECTICIDE AGENTS
DK1077927T3 (en) New Substituted Cyclic Compounds, Methods of Preparation thereof, and Pharmaceutical Compositions Containing These
NO973635L (en) Method of inhibiting cell-cell adhesion
YU9802A (en) Cell adhesion inhibitors
NO971538L (en) Purine and guanine compounds as inhibitors of PNP
NO963370L (en) Novel mercaptoacetylamido-1,3,4,5-tetrahydrobenzo [cazazepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ACE
NO984740L (en) Isatin derivatives such as acetylcholinesterase inhibitors and analgesics
NO971625L (en) Novel peptides with immunomodulatory effects
NO944926L (en) Methods for Inhibiting Myeloperoxidase Activity
HUP9901093A2 (en) Use of benzotiophene derivatives for production of pharmaceuticals inhibiting melanoma
NO933837L (en) 4-aryl-3- (heteroarylureido) quinoline derivatives
ES2016017A6 (en) 1,1-dioxo-cephem-4-carbothiolic acid derivatives.
ATE158301T1 (en) 4-AZA-PREGNAN-5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS
ES2103675A1 (en) New substituted piperidines
TW346483B (en) Benzene derivatives
NO981909L (en) Fungicidal Compounds (B)
PT713702E (en) ANSIOLITIC AGENT
NO944909L (en) Methods for inhibiting male infertility