YU39750B - Process for obtaining 2-deutero-3-fluoro-d,l-alanine - Google Patents

Process for obtaining 2-deutero-3-fluoro-d,l-alanine

Info

Publication number: YU39750B
Authority: YU; Yugoslavia
Prior art keywords: deutero; alanine; fluoro; obtaining
Prior art date: 1974-11-08

Application number

YU2722/75A

Other languages

English (en)

Other versions

YU272275A (en

Inventor

U H Dolling

E J J Grabowski

E F Schoenewaldt

M Sletzinger

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-11-08

Filing date

1975-10-27

Publication date

1985-04-30

1975-10-27 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1982-02-28 Publication of YU272275A publication Critical patent/YU272275A/xx

1985-04-30 Publication of YU39750B publication Critical patent/YU39750B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
- C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

YU2722/75A 1974-11-08 1975-10-27 Process for obtaining 2-deutero-3-fluoro-d,l-alanine YU39750B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/522,185 US3972921A (en)	1974-11-08	1974-11-08	Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

Publications (2)

Publication Number	Publication Date
YU272275A YU272275A (en)	1982-02-28
YU39750B true YU39750B (en)	1985-04-30

Family

ID=24079796

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU2722/75A YU39750B (en)	1974-11-08	1975-10-27	Process for obtaining 2-deutero-3-fluoro-d,l-alanine

Country Status (26)

Country	Link
US (1)	US3972921A (es)
JP (1)	JPS5926614B2 (es)
AR (1)	AR208722A1 (es)
AT (1)	AT344136B (es)
BE (1)	BE835358A (es)
CA (1)	CA1053697A (es)
CH (1)	CH622772A5 (es)
CS (1)	CS199501B2 (es)
DD (1)	DD125839A5 (es)
DE (1)	DE2550121C2 (es)
DK (1)	DK474375A (es)
ES (1)	ES442154A1 (es)
FI (1)	FI752919A (es)
FR (1)	FR2290418A1 (es)
GB (1)	GB1480886A (es)
HU (1)	HU172273B (es)
IE (1)	IE42060B1 (es)
IT (1)	IT1048054B (es)
LU (1)	LU73734A1 (es)
NL (1)	NL7512383A (es)
NO (1)	NO147671C (es)
PL (1)	PL102608B1 (es)
SE (1)	SE7511734L (es)
SU (1)	SU626689A3 (es)
YU (1)	YU39750B (es)
ZA (1)	ZA757012B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4028405A (en) *	1974-10-15	1977-06-07	Merck & Co., Inc.	Fluorinated amino acids
US4049708A (en) *	1976-03-04	1977-09-20	Merck & Co., Inc.	Fluorodesulfurization of alkyl mercaptans or alkyl dithianes
NZ194348A (en) *	1979-07-26	1982-09-14	Merrell Toraude & Co	Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
JPS56113733A (en) *	1979-12-29	1981-09-07	Daikin Ind Ltd	3-substituted-3-fluoropyruvic acid, its ester, salt and preparation thereof
US4582931A (en) *	1984-12-24	1986-04-15	Merck & Co., Inc.	Preparation of 2-Deutero-D-serine
US5254730A (en) *	1992-01-14	1993-10-19	Kilgore James L	Production of amino acids and amino acid derivatives bearing isotopic hydrogen labels
FR2707309B1 (fr) *	1993-07-09	1995-08-11	Trefileurope France Sa	Câble de levage.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2610212A (en) *	1950-04-24	1952-09-09	Gen Mills Inc	Synthesis of amino acids
US2839547A (en) *	1955-07-30	1958-06-17	Inventa Ag	Process for the production of aminocarboxylic acids
JPS4936389B1 (es) *	1969-03-03	1974-09-30
US3585361A (en) *	1969-06-18	1971-06-15	Nordson Corp	Supply system for heating and dispensing molten thermoplastic material
JPS4841007B1 (es) *	1970-10-22	1973-12-04
JPS5225415B2 (es) *	1972-01-17	1977-07-07
JPS4935435A (es) *	1972-08-09	1974-04-02

1974
- 1974-11-08 US US05/522,185 patent/US3972921A/en not_active Expired - Lifetime
1975
- 1975-10-20 FI FI752919A patent/FI752919A/fi not_active Application Discontinuation
- 1975-10-20 SE SE7511734A patent/SE7511734L/xx unknown
- 1975-10-22 DK DK474375A patent/DK474375A/da not_active Application Discontinuation
- 1975-10-22 NL NL7512383A patent/NL7512383A/xx not_active Application Discontinuation
- 1975-10-23 NO NO753561A patent/NO147671C/no unknown
- 1975-10-27 CA CA238,618A patent/CA1053697A/en not_active Expired
- 1975-10-27 GB GB44182/75A patent/GB1480886A/en not_active Expired
- 1975-10-27 YU YU2722/75A patent/YU39750B/xx unknown
- 1975-10-28 AR AR260981A patent/AR208722A1/es active
- 1975-10-28 ES ES442154A patent/ES442154A1/es not_active Expired
- 1975-10-31 IT IT52036/75A patent/IT1048054B/it active
- 1975-10-31 SU SU752185056A patent/SU626689A3/ru active
- 1975-10-31 HU HU75ME00001914A patent/HU172273B/hu unknown
- 1975-11-04 CS CS757421A patent/CS199501B2/cs unknown
- 1975-11-04 AT AT838775A patent/AT344136B/de not_active IP Right Cessation
- 1975-11-05 DD DD189260A patent/DD125839A5/xx unknown
- 1975-11-05 FR FR7533779A patent/FR2290418A1/fr active Granted
- 1975-11-05 IE IE2407/75A patent/IE42060B1/en unknown
- 1975-11-06 CH CH1435875A patent/CH622772A5/de not_active IP Right Cessation
- 1975-11-06 LU LU73734A patent/LU73734A1/xx unknown
- 1975-11-06 PL PL1975184521A patent/PL102608B1/pl unknown
- 1975-11-07 JP JP50133150A patent/JPS5926614B2/ja not_active Expired
- 1975-11-07 BE BE161682A patent/BE835358A/xx not_active IP Right Cessation
- 1975-11-07 DE DE2550121A patent/DE2550121C2/de not_active Expired
- 1975-11-07 ZA ZA757012A patent/ZA757012B/xx unknown

Also Published As

Publication number	Publication date
NO147671C (no)	1983-05-25
SE7511734L (sv)	1976-05-10
IE42060L (en)	1976-05-08
AR208722A1 (es)	1977-02-28
FI752919A (es)	1976-05-09
DD125839A5 (es)	1977-05-25
NO753561L (es)	1976-05-11
GB1480886A (en)	1977-07-27
CS199501B2 (en)	1980-07-31
YU272275A (en)	1982-02-28
AU8605675A (en)	1977-05-05
ZA757012B (en)	1977-06-29
FR2290418B1 (es)	1979-01-05
PL102608B1 (pl)	1979-04-30
HU172273B (hu)	1978-07-28
CH622772A5 (es)	1981-04-30
IT1048054B (it)	1980-11-20
ES442154A1 (es)	1977-07-01
CA1053697A (en)	1979-05-01
DK474375A (da)	1976-05-09
IE42060B1 (en)	1980-05-21
DE2550121A1 (de)	1976-05-20
SU626689A3 (ru)	1978-09-30
AT344136B (de)	1978-07-10
US3972921A (en)	1976-08-03
NL7512383A (nl)	1976-05-11
DE2550121C2 (de)	1984-08-16
NO147671B (no)	1983-02-14
ATA838775A (de)	1977-11-15
FR2290418A1 (fr)	1976-06-04
JPS5926614B2 (ja)	1984-06-29
LU73734A1 (es)	1976-09-06
BE835358A (fr)	1976-05-07
JPS5170722A (en)	1976-06-18

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