YU36952B - Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and-morphinanes - Google Patents

Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and-morphinanes

Info

Publication number: YU36952B
Authority: YU; Yugoslavia
Prior art keywords: morphinanes; benzomorphanes; methoxymethyl; furyl; methyl
Prior art date: 1973-10-27

Application number

YU2853/74A

Other languages

English (en)

Other versions

YU285374A (en

Inventor

H Merz

A Langbein

G Walther

K Stockhaus

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-27

Filing date

1974-10-24

Publication date

1984-08-31

1974-10-24 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1982-06-18 Publication of YU285374A publication Critical patent/YU285374A/xx

1984-08-31 Publication of YU36952B publication Critical patent/YU36952B/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

YU2853/74A 1973-10-27 1974-10-24 Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and-morphinanes YU36952B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19732354002 DE2354002A1 (de)	1973-10-27	1973-10-27	Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (2)

Publication Number	Publication Date
YU285374A YU285374A (en)	1982-06-18
YU36952B true YU36952B (en)	1984-08-31

Family

ID=5896658

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
YU2853/74A YU36952B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and-morphinanes
YU2856/74A YU36950B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxymethyl-furyl-methyl-6,7-benzomorphanes and - morphinanes
YU2854/74A YU36949B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and - morphinanes
YU02852/74A YU36519B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxy-methylfurylmethyl)-6,7-benzomorphanes and - morphinanes
YU2851/74A YU36951B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxymethyl-furylmethyl)-6,7-benzomorphanes and - morphinanes

Family Applications After (4)

Application Number	Title	Priority Date	Filing Date
YU2856/74A YU36950B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxymethyl-furyl-methyl-6,7-benzomorphanes and - morphinanes
YU2854/74A YU36949B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxymethyl-furyl-methyl)-6,7-benzomorphanes and - morphinanes
YU02852/74A YU36519B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxy-methylfurylmethyl)-6,7-benzomorphanes and - morphinanes
YU2851/74A YU36951B (en)	1973-10-27	1974-10-24	Process for preparing new n-(methoxymethyl-furylmethyl)-6,7-benzomorphanes and - morphinanes

Country Status (27)

Country	Link
US (1)	US3981874A (no)
JP (1)	JPS5738590B2 (no)
AT (6)	AT336202B (no)
BE (1)	BE821505A (no)
BG (3)	BG27902A3 (no)
CA (1)	CA1056377A (no)
CH (6)	CH609048A5 (no)
CS (3)	CS171195B2 (no)
DD (1)	DD115909A5 (no)
DE (1)	DE2354002A1 (no)
DK (1)	DK138325C (no)
ES (6)	ES431056A1 (no)
FI (1)	FI62079C (no)
FR (1)	FR2248838B1 (no)
GB (1)	GB1482552A (no)
HU (1)	HU176479B (no)
IE (1)	IE41528B1 (no)
IL (1)	IL45938A (no)
NL (1)	NL7413980A (no)
NO (1)	NO140859C (no)
PH (1)	PH11894A (no)
PL (3)	PL92053B1 (no)
RO (5)	RO65656A (no)
SE (1)	SE422791B (no)
SU (6)	SU510999A3 (no)
YU (5)	YU36952B (no)
ZA (1)	ZA746790B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1513961A (en) *	1975-02-25	1978-06-14	Acf Chemiefarma Nv	6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) *	1978-11-30	1980-06-17	Sterling Drug Inc.	11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
AR067673A1 (es)	2007-07-26	2009-10-21	Vitae Pharmaceuticals Inc	Derivados de 1,3 oxazinan - 2 - ona como inhibidores ciclicos de la 11 beta -hidroxiesteroide deshidrogenasa 1. composiciones farmaceuticas.
AR069545A1 (es) *	2007-11-16	2010-02-03	Boehringer Ingelheim Pharma	Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y
US8440658B2 (en)	2007-12-11	2013-05-14	Vitae Pharmaceuticals, Inc.	Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en)	2008-01-24	2009-07-30	Vitae Pharmaceuticals, Inc.	Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US20110028445A1 (en) *	2008-02-12	2011-02-03	Boehringer Ingelheim International Gmbh	Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
JP5730021B2 (ja)	2008-02-15	2015-06-03	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
ES2421537T3 (es)	2008-05-01	2013-09-03	Vitae Pharmaceuticals Inc	Inhibidores cíclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
US8569292B2 (en)	2008-05-01	2013-10-29	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
CA2723034A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071719A1 (es)	2008-05-13	2010-07-07	Boehringer Ingelheim Int	Derivados aliciclicos de acido carboxilico de benzomorfanos y estructuras relacionadas, medicamentos que contienen dichos compuestos y su uso.procesos de obtencion
US8846668B2 (en)	2008-07-25	2014-09-30	Vitae Pharmaceuticals, Inc.	Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
PL2324018T3 (pl)	2008-07-25	2014-02-28	Boehringer Ingelheim Int	Cykliczne inhibitory dehydrogenazy 11 beta-hydroksysteroidowej typu 1
US8680093B2 (en)	2009-04-30	2014-03-25	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8927539B2 (en)	2009-06-11	2015-01-06	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
UY33001A (es) *	2009-11-06	2011-05-31	Boehringer Ingelheim Int	Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
US8933072B2 (en)	2010-06-16	2015-01-13	Vitae Pharmaceuticals, Inc.	Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
EP2744783A1 (en)	2011-08-17	2014-06-25	Boehringer Ingelheim International GmbH	Indenopyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3632591A (en) *	1968-07-19	1972-01-04	Sterling Drug Inc	1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) *	1968-12-26	1974-09-03	Sumitomo Chemical Co	2-aroylalkyl benzomorphans
CS166804B2 (no) *	1971-02-08	1976-03-29	Boehringer Sohn Ingelheim

1973
- 1973-10-25 SU SU2069684A patent/SU510999A3/ru active
- 1973-10-25 SU SU2069691A patent/SU511005A3/ru active
- 1973-10-27 DE DE19732354002 patent/DE2354002A1/de not_active Withdrawn
1974
- 1974-01-25 RO RO7480315A patent/RO65656A/ro unknown
- 1974-10-02 CS CS6768A patent/CS171195B2/cs unknown
- 1974-10-02 CS CS6769A patent/CS171196B2/cs unknown
- 1974-10-02 CS CS6767A patent/CS171194B2/cs unknown
- 1974-10-15 US US05/514,474 patent/US3981874A/en not_active Expired - Lifetime
- 1974-10-16 ES ES431056A patent/ES431056A1/es not_active Expired
- 1974-10-16 ES ES431054A patent/ES431054A1/es not_active Expired
- 1974-10-16 AT AT828974A patent/AT336202B/de not_active IP Right Cessation
- 1974-10-16 AT AT828874A patent/AT335076B/de active
- 1974-10-16 AT AT828674A patent/AT335632B/de not_active IP Right Cessation
- 1974-10-16 AT AT828774A patent/AT335633B/de not_active IP Right Cessation
- 1974-10-16 AT AT828574A patent/AT335631B/de not_active IP Right Cessation
- 1974-10-16 ES ES431058A patent/ES431058A1/es not_active Expired
- 1974-10-16 ES ES431059A patent/ES431059A1/es not_active Expired
- 1974-10-16 ES ES431057A patent/ES431057A1/es not_active Expired
- 1974-10-16 ES ES431055A patent/ES431055A1/es not_active Expired
- 1974-10-16 AT AT829074A patent/AT335634B/de not_active IP Right Cessation
- 1974-10-24 PH PH16448A patent/PH11894A/en unknown
- 1974-10-24 CH CH1426474A patent/CH609048A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2853/74A patent/YU36952B/xx unknown
- 1974-10-24 CH CH1426374A patent/CH609047A5/xx not_active IP Right Cessation
- 1974-10-24 CH CH1426574A patent/CH609340A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2856/74A patent/YU36950B/xx unknown
- 1974-10-24 YU YU2854/74A patent/YU36949B/xx unknown
- 1974-10-24 YU YU02852/74A patent/YU36519B/xx unknown
- 1974-10-24 CH CH1426274A patent/CH609046A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2851/74A patent/YU36951B/xx unknown
- 1974-10-25 BG BG7428037A patent/BG27902A3/xx unknown
- 1974-10-25 FR FR7435890A patent/FR2248838B1/fr not_active Expired
- 1974-10-25 RO RO7480316A patent/RO65657A/ro unknown
- 1974-10-25 BE BE149902A patent/BE821505A/xx not_active IP Right Cessation
- 1974-10-25 RO RO7480314A patent/RO65655A/ro unknown
- 1974-10-25 BG BG7428036A patent/BG27901A3/xx unknown
- 1974-10-25 BG BG7428038A patent/BG27903A3/xx unknown
- 1974-10-25 SU SU2070657A patent/SU508193A3/ru active
- 1974-10-25 CH CH1437074A patent/CH609686A5/xx not_active IP Right Cessation
- 1974-10-25 CA CA212,340A patent/CA1056377A/en not_active Expired
- 1974-10-25 FI FI3141/74A patent/FI62079C/fi active
- 1974-10-25 RO RO7480318A patent/RO65659A/ro unknown
- 1974-10-25 JP JP12261074A patent/JPS5738590B2/ja not_active Expired
- 1974-10-25 DD DD181929A patent/DD115909A5/xx unknown
- 1974-10-25 SE SE7413485A patent/SE422791B/xx unknown
- 1974-10-25 SU SU7402069685A patent/SU578870A3/ru active
- 1974-10-25 ZA ZA00746790A patent/ZA746790B/xx unknown
- 1974-10-25 SU SU2069689A patent/SU508192A3/ru active
- 1974-10-25 HU HU74BO1521A patent/HU176479B/hu unknown
- 1974-10-25 IE IE2206/74A patent/IE41528B1/en unknown
- 1974-10-25 NO NO743845A patent/NO140859C/no unknown
- 1974-10-25 RO RO7480317A patent/RO65658A/ro unknown
- 1974-10-25 SU SU2070713A patent/SU512707A3/ru active
- 1974-10-25 DK DK559874A patent/DK138325C/da not_active IP Right Cessation
- 1974-10-25 NL NL7413980A patent/NL7413980A/xx unknown
- 1974-10-25 CH CH1436974A patent/CH609685A5/xx not_active IP Right Cessation
- 1974-10-25 GB GB46323/74A patent/GB1482552A/en not_active Expired
- 1974-10-25 IL IL45938A patent/IL45938A/en unknown
- 1974-10-26 PL PL1974175142A patent/PL92053B1/pl unknown
- 1974-10-26 PL PL1974175144A patent/PL92086B1/pl unknown
- 1974-10-26 PL PL1974175143A patent/PL92052B1/pl unknown

Also Published As

Publication number	Publication date
FR2248838A1 (no)	1975-05-23
BG27901A3 (en)	1980-01-15
ATA828774A (de)	1976-07-15
AT335631B (de)	1977-03-25
PH11894A (en)	1978-08-29
IE41528L (en)	1975-04-27
CH609047A5 (no)	1979-02-15
SU578870A3 (ru)	1977-10-30
RO65659A (ro)	1980-06-15
ES431059A1 (es)	1976-10-16
FI314174A (no)	1975-04-28
CA1056377A (en)	1979-06-12
YU285174A (en)	1982-06-18
CH609686A5 (no)	1979-03-15
DD115909A5 (no)	1975-10-20
YU285474A (en)	1982-06-18
SU508193A3 (ru)	1976-03-25
IE41528B1 (en)	1980-01-30
AT335634B (de)	1977-03-25
RO65658A (fr)	1979-07-15
ATA828874A (de)	1976-06-15
YU36949B (en)	1984-08-31
GB1482552A (en)	1977-08-10
RO65657A (ro)	1980-06-15
SU508192A3 (ru)	1976-03-25
RO65655A (ro)	1980-06-15
ATA828574A (de)	1976-07-15
JPS5738590B2 (no)	1982-08-16
NO140859C (no)	1979-11-28
ES431054A1 (es)	1976-10-16
RO65656A (ro)	1980-06-15
ES431056A1 (es)	1976-10-16
AT335633B (de)	1977-03-25
FI62079C (fi)	1982-11-10
HU176479B (en)	1981-03-28
BE821505A (fr)	1975-04-25
ATA829074A (de)	1976-07-15
BG27903A3 (en)	1980-01-15
IL45938A (en)	1977-12-30
YU36519B (en)	1984-02-29
SU511005A3 (ru)	1976-04-15
CS171196B2 (no)	1976-10-29
FI62079B (fi)	1982-07-30
NO743845L (no)	1975-05-26
CH609340A5 (no)	1979-02-28
SU510999A3 (ru)	1976-04-15
JPS5071679A (no)	1975-06-13
NO140859B (no)	1979-08-20
AT335076B (de)	1977-02-25
ES431058A1 (es)	1976-10-16
SE7413485L (no)	1975-04-28
DE2354002A1 (de)	1975-05-07
SE422791B (sv)	1982-03-29
FR2248838B1 (no)	1977-11-04
PL92053B1 (no)	1977-03-31
CS171195B2 (no)	1976-10-29
YU285374A (en)	1982-06-18
CH609048A5 (no)	1979-02-15
ES431055A1 (es)	1976-10-16
BG27902A3 (en)	1980-01-15
PL92086B1 (no)	1977-03-31
DK138325B (da)	1978-08-14
DK559874A (no)	1975-06-23
ATA828674A (de)	1976-07-15
YU36950B (en)	1984-08-31
YU36951B (en)	1984-08-31
CH609685A5 (no)	1979-03-15
IL45938A0 (en)	1974-12-31
SU512707A3 (ru)	1976-04-30
US3981874A (en)	1976-09-21
CH609046A5 (no)	1979-02-15
YU285674A (en)	1982-06-18
PL92052B1 (no)	1977-03-31
AT335632B (de)	1977-03-25
ES431057A1 (es)	1976-10-16
NL7413980A (nl)	1975-04-29
DK138325C (da)	1979-01-22
AT336202B (de)	1977-04-25
ATA828974A (de)	1976-08-15
CS171194B2 (no)	1976-10-29
ZA746790B (en)	1976-06-30
YU285274A (en)	1982-02-25

Publication	Publication Date	Title
YU128774A (en)	1982-05-31	Process for preparing triazolyl-o,n-acetals
CS180644B2 (en)	1978-01-31	Process for preparing nonapeptides
YU36951B (en)	1984-08-31	Process for preparing new n-(methoxymethyl-furylmethyl)-6,7-benzomorphanes and - morphinanes
HU173540B (hu)	1979-06-28	Sposob poluchenija novykh proizvodnykh 5-oksa-prostaglandina
YU235174A (en)	1982-06-30	Process for preparing dodeca-7,9-diene-1-yl-acetate
YU309281A (en)	1983-06-30	Process for preparing new dibenzoxepine derivatives
CS182300B2 (en)	1978-04-28	Process for preparing 1,3-oxidated 8alfa-estratrienes
HU173426B (hu)	1979-05-28	Sposob poluchenija 1-oksida slozhnogo metoksi-metilovogo efira 6-fenoksiacetamodo-2,2-dimetil-penam-3-karbonovojj kisloty
HU172656B (hu)	1978-11-28	Sposob poluchenija novykh d-homo-steroidov
HU172196B (hu)	1978-06-28	Sposob poluchenija novykh zamehhjonnykh ciklogeksantetrolov
YU36918B (en)	1984-08-31	New process for preparing 4-amino-3,5-dihalo-phenyl-ethanol-amines
HU172290B (hu)	1978-07-28	Sposob poluchenija zamehhjonnogo 7h-indolizino/5,6,7-ij/ izokhinolina
YU36369B (en)	1983-06-30	New process for preparing 2-acilamino-benzylamines
YU170574A (en)	1982-06-18	New process for preparing 2-amino-benzylamines
HU171180B (hu)	1977-11-28	Sposob poluchenija 4,5-seko-steroidov
YU35370B (en)	1980-12-31	Process for preparing 9delta-fluoro-11beta,21-dihydroxy-16delta,17delta-isopropylidene-dioxy-1,4-pregnadiene-2,20-dion-21-valerate
YU167073A (en)	1980-06-30	Process for preparing 2-aminomethyl-4,4-diethyl-4h-1,3-benzoxazines
HU173821B (hu)	1979-08-28	Sposob poluchenija novykh proizvodnykh 2 - gidroksi - 3 - amino - propana
HU170956B (hu)	1977-10-28	Sposob poluchenija o,o-dialkil-ftalimido-fosfonotioatov
KR780000654B1 (en)	1978-12-18	Process for preparing 11,12-secoprostaglandins
YU156780A (en)	1983-04-27	Process for preparing new heterocyclyloxy-2-hydroxy-3-aminopropanes
CS187447B2 (en)	1979-01-31	Process for preparing new oxoalkylpyridines
CS187408B2 (en)	1979-01-31	Process for preparing new oxoalkylpyridines
HU171754B (hu)	1978-03-28	Sposob poluchenija proizvodnykh 2-aminometil-4,6-digalogen-fenola
CS189820B1 (en)	1979-05-31	Process for preparing 2,5-dichlor-1,4-phenylendiamine