YU2703A - Bistar vodeni anestetski preparat - Google Patents
Bistar vodeni anestetski preparatInfo
- Publication number
- YU2703A YU2703A YU2703A YUP2703A YU2703A YU 2703 A YU2703 A YU 2703A YU 2703 A YU2703 A YU 2703A YU P2703 A YUP2703 A YU P2703A YU 2703 A YU2703 A YU 2703A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- clear aqueous
- propofol
- compositions
- anesthetic composition
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Opisani su sterilni farmaceutski stabini autoklavirani bistri preparati propofola (2,6-diizopropil fenol) podesni za parenteralnu primenu. Preparati se uglavnom sastoje od kompleksa propofola sa 2-hidroksipropil-ГЎ-ciklodekstrinom pri masenom odnosu 1:30 do 1:60. Ovaj kompleks propofola sa 2-hidroksipropil-ГЎ-ciklodekstrinom daje bistar vodeni preparat koji je stabilan prema autoklaviranju. Preparat je efikasan kao anestetski agens. Opisan je postupak za dobijanje ovih sinergističkih preparata.[Sterile pharmaceutical stable autoclaved clear aqueous compositions of propofol (2,6-Diisopropyl phenol) suitable for parenteral administration are described. The compositions essentially consist of a complex of propofol with 2-hydroxypropyl-ГЎ-cyclodextrin in a weight ratio of 1:30 - 1:60. This complex of propofol with 2-hydroxypropyl-ГЎ-cyclodextrin produces a clear aqueous composition that is stable to autoclaving. The composition is effective as an anaesthetic agent. The process of making these synergistic compositions has been described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN573MU2000 IN187686B (sh) | 2000-06-21 | 2000-06-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU2703A true YU2703A (sh) | 2006-03-03 |
Family
ID=11097257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU2703A YU2703A (sh) | 2000-06-21 | 2000-12-14 | Bistar vodeni anestetski preparat |
Country Status (26)
Country | Link |
---|---|
US (1) | US7138387B2 (sh) |
EP (1) | EP1299095B1 (sh) |
JP (1) | JP4907833B2 (sh) |
KR (1) | KR100810066B1 (sh) |
CN (1) | CN1254237C (sh) |
AP (1) | AP2002002674A0 (sh) |
AT (1) | ATE267592T1 (sh) |
AU (2) | AU3597201A (sh) |
BG (1) | BG107463A (sh) |
BR (1) | BR0017268A (sh) |
CA (1) | CA2414064C (sh) |
DE (1) | DE60011149T2 (sh) |
DK (1) | DK1299095T3 (sh) |
EA (1) | EA005589B1 (sh) |
ES (1) | ES2222271T3 (sh) |
HU (1) | HUP0301646A3 (sh) |
IL (1) | IL153387A0 (sh) |
IN (1) | IN187686B (sh) |
MX (1) | MXPA02012611A (sh) |
NO (1) | NO20025999D0 (sh) |
NZ (1) | NZ523643A (sh) |
PL (1) | PL359624A1 (sh) |
PT (1) | PT1299095E (sh) |
WO (1) | WO2001097796A1 (sh) |
YU (1) | YU2703A (sh) |
ZA (1) | ZA200300336B (sh) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN188917B (sh) * | 2000-12-07 | 2002-11-23 | Bharat Surums & Vaccines Ltd | |
US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
JP2005517679A (ja) * | 2001-12-28 | 2005-06-16 | ギルフォード ファーマシューティカルズ インコーポレイテッド | プロポフォールの水溶性プロドラッグの水ベースの薬学的製剤 |
DE60305438T2 (de) * | 2002-02-01 | 2006-12-21 | Shimoda Biotech (Pty.) Ltd., Mill Park | Lyophilisierte pharmazeutische zusammensetzung von propofol |
US7550155B2 (en) | 2002-07-29 | 2009-06-23 | Transform Pharmaceuticals Inc. | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses |
EP1539122B1 (en) | 2002-07-29 | 2014-01-29 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
TR200502189T1 (tr) * | 2002-12-09 | 2007-01-22 | American Bioscience, Inc. | Kompozisyonlar ve farmakolojik etken maddelerin aktarımı için yöntemler. |
EP1704858A4 (en) * | 2004-01-14 | 2008-06-04 | Otsuka Pharma Co Ltd | PROPOFOL-CONTAINING FAT-EMULSION PREPARATION |
BRPI0515181A (pt) * | 2004-09-13 | 2008-07-22 | Bharat Serums & Vaccines Ltd | composição de óleo-em-água estéril para administração intravenosa, uso de um monoglicerìdeo e processo de preparação de uma composição para administração intravenosa |
JP2009504634A (ja) * | 2005-08-12 | 2009-02-05 | ブハラット セルムズ アンド ヴァクシンズ リミテッド | プロポフォールを含む水性麻酔剤組成物 |
WO2007128866A2 (en) * | 2006-05-09 | 2007-11-15 | Novobion Oy | Novel chemical compositions |
TWI498395B (zh) * | 2008-03-11 | 2015-09-01 | 3M Innovative Properties Co | 硬塗層組合物 |
WO2010148288A2 (en) * | 2009-06-19 | 2010-12-23 | Lyotropic Therapeutics, Inc. | Pharmaceutical formulations with low aqueous levels of free unbound drug |
WO2011011167A2 (en) | 2009-07-21 | 2011-01-27 | 3M Innovative Properties Company | Curable composition, method of coating a phototool, and coated phototool |
CN102686642B (zh) | 2009-09-16 | 2016-06-29 | 3M创新有限公司 | 氟化涂料和用其制作的底片 |
KR101768237B1 (ko) | 2009-09-16 | 2017-08-14 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 플루오르화된 코팅 및 그로 제조된 포토툴 |
US8268067B2 (en) * | 2009-10-06 | 2012-09-18 | 3M Innovative Properties Company | Perfluoropolyether coating composition for hard surfaces |
EP2345427A1 (de) * | 2010-01-14 | 2011-07-20 | SapioTec GmbH | Flurankomplex |
DK2484350T3 (en) * | 2011-02-04 | 2016-08-01 | Norbert Univ -Prof Dr Med Roewer | A pharmaceutical composition containing a complex of a cyclodextrin with a propofolsalt |
AU2013273764B2 (en) * | 2011-11-29 | 2016-05-05 | Zoetis Services Llc | Pharmaceutical compositions |
DK2785352T3 (da) | 2011-11-29 | 2020-05-25 | Jurox Pty Ltd | Stabile injicerbare farmaceutiske sammensætninger omfattende 2-hydroxypropyl-beta-cyclodextrin og alfaxalon |
CN103263404B (zh) * | 2012-04-28 | 2017-12-01 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种复合***物 |
WO2017132243A1 (en) * | 2016-01-29 | 2017-08-03 | Cuda Anesthetics, Llc | Aqueous pharmaceutical formulation comprising propofol |
FR3117337B1 (fr) | 2020-12-10 | 2023-04-28 | Centre Hospitalier Univ De Lille | Composition pharmaceutique contenant du propofol, une cyclodextrine ou un dérivé de cyclodextrine et un sel pharmaceuticalement acceptable |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA962214B (en) * | 1995-04-10 | 1996-10-07 | Farmarc Nederland Bv | Pharmaceutical composition |
-
2000
- 2000-06-21 IN IN573MU2000 patent/IN187686B/en unknown
- 2000-12-14 IL IL15338700A patent/IL153387A0/xx not_active IP Right Cessation
- 2000-12-14 MX MXPA02012611A patent/MXPA02012611A/es active IP Right Grant
- 2000-12-14 BR BR0017268-5A patent/BR0017268A/pt not_active Application Discontinuation
- 2000-12-14 PT PT00991825T patent/PT1299095E/pt unknown
- 2000-12-14 ES ES00991825T patent/ES2222271T3/es not_active Expired - Lifetime
- 2000-12-14 DE DE60011149T patent/DE60011149T2/de not_active Expired - Lifetime
- 2000-12-14 AU AU3597201A patent/AU3597201A/xx active Pending
- 2000-12-14 HU HU0301646A patent/HUP0301646A3/hu unknown
- 2000-12-14 CN CNB008198292A patent/CN1254237C/zh not_active Expired - Fee Related
- 2000-12-14 EA EA200300047A patent/EA005589B1/ru not_active IP Right Cessation
- 2000-12-14 CA CA2414064A patent/CA2414064C/en not_active Expired - Fee Related
- 2000-12-14 WO PCT/IN2000/000124 patent/WO2001097796A1/en active IP Right Grant
- 2000-12-14 EP EP00991825A patent/EP1299095B1/en not_active Expired - Lifetime
- 2000-12-14 YU YU2703A patent/YU2703A/sh unknown
- 2000-12-14 AT AT00991825T patent/ATE267592T1/de active
- 2000-12-14 AP APAP/P/2002/002674A patent/AP2002002674A0/en unknown
- 2000-12-14 PL PL00359624A patent/PL359624A1/xx unknown
- 2000-12-14 DK DK00991825T patent/DK1299095T3/da active
- 2000-12-14 KR KR1020027017362A patent/KR100810066B1/ko not_active IP Right Cessation
- 2000-12-14 US US10/296,765 patent/US7138387B2/en not_active Expired - Lifetime
- 2000-12-14 NZ NZ523643A patent/NZ523643A/en not_active IP Right Cessation
- 2000-12-14 JP JP2002503273A patent/JP4907833B2/ja not_active Expired - Fee Related
- 2000-12-14 AU AU2001235972A patent/AU2001235972B2/en not_active Ceased
-
2002
- 2002-12-13 NO NO20025999A patent/NO20025999D0/no not_active Application Discontinuation
-
2003
- 2003-01-13 ZA ZA200300336A patent/ZA200300336B/en unknown
- 2003-01-16 BG BG107463A patent/BG107463A/xx unknown
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