YU124291A - N-i n'-supstituisani sulfonilkarbamidi i postupci za njihovo dobijanje - Google Patents
N-i n'-supstituisani sulfonilkarbamidi i postupci za njihovo dobijanjeInfo
- Publication number
- YU124291A YU124291A YU124291A YU124291A YU124291A YU 124291 A YU124291 A YU 124291A YU 124291 A YU124291 A YU 124291A YU 124291 A YU124291 A YU 124291A YU 124291 A YU124291 A YU 124291A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- processes
- carbamids
- obtaining
- substituted sulphonyl
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
N-I N'-SUPSTITUISANI SULFONILKARBAMIDI I POSTUPCI ZA NJIHOVO DOBIJANJE, opisana su jedinjenja formule I u kojima X1 i X2 su nezavisno vodonik, halo, trifluorometil ili metil pod uslovom što najmanje jedan od X1 i X2 je hlor, brom, fluor, ili trifluorometil; gde: Z je kiseonik, azot ili sumpor; R1, R2, R3 i R4 su nezavisno vodonik, halo, C1-3 alkil, C1-C3 alkoksi, ili C1-C3 alkiltio pod uslovom što kada A je najmanje jedan od R1, R2, ili R3 je supstituent različit od vodonika, kao i njihove farmaceutski prihvatljive soli.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55422690A | 1990-07-17 | 1990-07-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU124291A true YU124291A (sh) | 1994-01-20 |
Family
ID=24212538
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU124291A YU124291A (sh) | 1990-07-17 | 1991-07-16 | N-i n'-supstituisani sulfonilkarbamidi i postupci za njihovo dobijanje |
Country Status (20)
Country | Link |
---|---|
US (1) | US5302724A (sh) |
EP (1) | EP0467613A1 (sh) |
JP (1) | JPH04234382A (sh) |
KR (1) | KR920002579A (sh) |
CN (1) | CN1058401A (sh) |
AU (1) | AU640499B2 (sh) |
BR (1) | BR9103036A (sh) |
CA (1) | CA2047103A1 (sh) |
CS (1) | CS219291A3 (sh) |
FI (1) | FI913432A (sh) |
HU (1) | HUT58698A (sh) |
IE (1) | IE912488A1 (sh) |
IL (1) | IL98784A0 (sh) |
MX (1) | MX9100165A (sh) |
NO (1) | NO912773L (sh) |
NZ (1) | NZ238911A (sh) |
PT (1) | PT98320A (sh) |
RU (1) | RU2022963C1 (sh) |
YU (1) | YU124291A (sh) |
ZA (1) | ZA915371B (sh) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5254582A (en) * | 1992-02-05 | 1993-10-19 | Eli Lilly And Company | Antitumor compositions and methods |
US5169860A (en) * | 1992-03-13 | 1992-12-08 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
US5387681A (en) * | 1992-08-19 | 1995-02-07 | Eli Lilly And Company | Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides |
US5300499A (en) * | 1992-09-02 | 1994-04-05 | Allergan, Inc. | 5-substituted 3-thiophene sulfonamides as antiglaucoma agents |
ZA941500B (en) * | 1993-03-10 | 1995-09-04 | Lilly Co Eli | Antitumor compositions and methods of treatment |
DE69708340T2 (de) * | 1996-08-22 | 2002-05-16 | Dong Wha Pharm Ind Co Ltd | Arylsulfonylimidazolon-derivate als antitumormittel |
AU4799797A (en) * | 1996-10-04 | 1998-04-24 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
DE60237512D1 (de) | 2001-02-28 | 2010-10-14 | Univ Temple | N-(aryl)-2-arylethensulfonamide und ihre therapeutischen anwendungen |
TWI281916B (en) * | 2001-10-25 | 2007-06-01 | Lilly Co Eli | Antitumor compounds and methods |
WO2003072063A2 (en) * | 2002-02-28 | 2003-09-04 | Temple University - Of The Commonwealth System Of Higher Education | Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders |
CN103450149B (zh) * | 2012-06-01 | 2015-10-14 | 中国科学院上海有机化学研究所 | 苯基噻吩磺酰胺类化合物及其制备方法和用途 |
CA2975192A1 (en) | 2015-02-16 | 2016-08-25 | The University Of Queensland | Sulfonylureas and related compounds and use of same |
EP3872070A1 (en) * | 2016-04-18 | 2021-09-01 | Novartis AG | Compounds and compositions for treating conditions associated with nlrp activity |
MA56075A (fr) | 2017-07-07 | 2022-04-06 | Inflazome Ltd | Nouveaux composés de sulfonamide carboxamide |
EP3668843A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
TW201910316A (zh) | 2017-08-15 | 2019-03-16 | 愛爾蘭商英弗雷佐姆有限公司 | 新穎化合物 |
US11905252B2 (en) | 2018-03-02 | 2024-02-20 | Inflazome Limited | Compounds |
CN109384764B (zh) * | 2018-12-12 | 2021-09-03 | 中国科学院上海有机化学研究所 | 苯基噻吩磺酰胺类化合物、药物组合物、其制备方法和应用 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3124597A (en) * | 1964-03-10 | |||
US3083207A (en) * | 1963-03-26 | Indolinesulfonylureas | ||
DE1144259B (de) * | 1956-05-29 | 1963-02-28 | Hoechst Ag | Verfahren zur Herstellung von Sulfonylharnstoffen |
US3097241A (en) * | 1956-08-10 | 1963-07-09 | Hoechst Ag | Nu-cyclohexane-sulphonyl-n'-(beta-phenylethyl)-urea |
CH361010A (de) * | 1957-05-24 | 1962-03-31 | Geigy Ag J R | Verfahren zur Herstellung von N'-substituierten N-Thiophensulfonylharnstoffen |
US3013072A (en) * | 1958-09-02 | 1961-12-12 | Pfizer & Co C | Novel process for the production of sulfonylureas |
US2979437A (en) * | 1958-09-02 | 1961-04-11 | Pfizer & Co C | Substituted styryl, and thienylethenyl, pyridylethenyl sulfonylureas and method of treating diabetes |
DE1159937B (de) * | 1960-06-29 | 1963-12-27 | Heyden Chem Fab | Verfahren zur Herstellung von Hydrindensulfonylharnstoffen |
US3097242A (en) * | 1960-06-29 | 1963-07-09 | Olin Mathieson | Hydrindene sulfonylureas |
US3102121A (en) * | 1961-06-29 | 1963-08-27 | Olin Mathieson | Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas |
DE1240866B (de) * | 1961-06-29 | 1967-05-24 | Heyden Chem Fab | Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen |
US3155721A (en) * | 1961-11-30 | 1964-11-03 | Lilly Co Eli | Novel sulfonylureas |
NL295122A (sh) * | 1962-04-11 | |||
US3849110A (en) * | 1963-01-07 | 1974-11-19 | Lilly Co Eli | Herbicidal method employing aryl-sulfonylureas or salts thereof |
US3736122A (en) * | 1969-04-10 | 1973-05-29 | C Tung | Method of controlling plant growth |
US4398939A (en) * | 1980-06-03 | 1983-08-16 | E. I. Du Pont De Nemours And Company | Herbicidal thiophenesulfonamides |
US4634465A (en) * | 1982-07-16 | 1987-01-06 | Ciba-Geigy Corporation | Fused N-phenylsulfonyl-N'-pyrimidinylureas and N-phenylsulfonyl-N'triazinylureas |
AU1862083A (en) * | 1982-09-02 | 1984-03-08 | Duphar International Research B.V. | Tumor growth inhibitors |
US4471757A (en) * | 1983-03-15 | 1984-09-18 | Rogers William W | Log support for fireplace |
IT1161220B (it) * | 1983-04-21 | 1987-03-18 | Montedison Spa | Diidro-benzofurano derivati ad attivita' erbicida |
US4620868A (en) * | 1983-12-27 | 1986-11-04 | Ishihara Sangyo Kaisha, Ltd. | N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3[halo-substituted ethenyl (or propenyl)]-2-thiophenesulfonamides useful as herbicides |
CA1208561A (en) * | 1984-01-19 | 1986-07-29 | Marius S. Brouwer | Pharmaceutical compositions containing benzoylurea compounds |
US4845128A (en) * | 1984-06-27 | 1989-07-04 | Eli Lilly And Company | N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides |
US4861366A (en) * | 1984-08-27 | 1989-08-29 | E. I. Du Pont De Nemours And Company | Herbicidal acetals and ketals |
IE860511L (en) * | 1985-03-01 | 1986-09-01 | Alfa Farmaceutici Spa | "Benzoyl urea derivatives having anti-tumor activity" |
GR862353B (en) * | 1985-09-23 | 1987-01-19 | Lilly Co Eli | Anti-tumor method and compounds |
EP0228237B1 (en) * | 1985-12-24 | 1989-11-23 | Merck & Co. Inc. | Substituted thiophene-2-sulfonamide antiglaucoma agents |
CA1331464C (en) * | 1987-05-12 | 1994-08-16 | Eli Lilly And Company | Anti-tumor method and compounds |
-
1991
- 1991-07-10 ZA ZA915371A patent/ZA915371B/xx unknown
- 1991-07-10 NZ NZ238911A patent/NZ238911A/xx unknown
- 1991-07-10 IL IL98784A patent/IL98784A0/xx unknown
- 1991-07-11 MX MX9100165A patent/MX9100165A/es unknown
- 1991-07-15 KR KR1019910012031A patent/KR920002579A/ko not_active Application Discontinuation
- 1991-07-15 CS CS912192A patent/CS219291A3/cs unknown
- 1991-07-15 HU HU912375A patent/HUT58698A/hu unknown
- 1991-07-15 NO NO91912773A patent/NO912773L/no unknown
- 1991-07-15 PT PT98320A patent/PT98320A/pt not_active Application Discontinuation
- 1991-07-15 EP EP91306373A patent/EP0467613A1/en not_active Withdrawn
- 1991-07-15 AU AU80444/91A patent/AU640499B2/en not_active Ceased
- 1991-07-16 JP JP3175066A patent/JPH04234382A/ja active Pending
- 1991-07-16 BR BR919103036A patent/BR9103036A/pt not_active Application Discontinuation
- 1991-07-16 CA CA002047103A patent/CA2047103A1/en not_active Abandoned
- 1991-07-16 IE IE248891A patent/IE912488A1/en unknown
- 1991-07-16 FI FI913432A patent/FI913432A/fi unknown
- 1991-07-16 CN CN91104931A patent/CN1058401A/zh active Pending
- 1991-07-16 RU SU915001153A patent/RU2022963C1/ru active
- 1991-07-16 YU YU124291A patent/YU124291A/sh unknown
-
1992
- 1992-04-29 US US07/875,902 patent/US5302724A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH04234382A (ja) | 1992-08-24 |
IE912488A1 (en) | 1992-01-29 |
NO912773D0 (no) | 1991-07-15 |
US5302724A (en) | 1994-04-12 |
MX9100165A (es) | 1992-02-28 |
NO912773L (no) | 1992-01-20 |
EP0467613A1 (en) | 1992-01-22 |
NZ238911A (en) | 1993-10-26 |
CA2047103A1 (en) | 1992-01-18 |
CS219291A3 (en) | 1992-09-16 |
PT98320A (pt) | 1992-05-29 |
IL98784A0 (en) | 1992-07-15 |
FI913432A0 (fi) | 1991-07-16 |
AU8044491A (en) | 1992-01-23 |
ZA915371B (en) | 1993-03-31 |
KR920002579A (ko) | 1992-02-28 |
RU2022963C1 (ru) | 1994-11-15 |
CN1058401A (zh) | 1992-02-05 |
AU640499B2 (en) | 1993-08-26 |
HUT58698A (en) | 1992-03-30 |
HU912375D0 (en) | 1991-12-30 |
BR9103036A (pt) | 1992-04-28 |
FI913432A (fi) | 1992-01-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
YU124291A (sh) | N-i n'-supstituisani sulfonilkarbamidi i postupci za njihovo dobijanje | |
YU17591A (sh) | Triazolni fungicidni agensi | |
FI962070A0 (fi) | Diaminosyklobuteeni-3,4-dioneja sileän lihaksen relaksantteina | |
HU9204032D0 (en) | Method for producing new polycyclic guanine derivatives and pharmaceutical preparatives containing them | |
ES8107157A1 (es) | Procedimiento para la preparacion de 2-cloro-6-nitroanilinas | |
DK0681581T3 (da) | Substituerede, kondenserede, pyrazolforbindelser og deres anvendelse som herbicider. | |
ES8801833A1 (es) | Un procedimiento para la preparacion de un compuesto. | |
MA22609A1 (fr) | Derives nouveaux de 4-benzoyl-isoxazole, leur procede de production, compositions les contenant et leur utilisation comme herbicides . | |
HUP9800112A2 (hu) | Ciánamido-szulfonil-bifonil-metil-helyettesített imidazolszármazékok, alkalmazésuk gyógyszerkészítmények előállítására, valamint a vegyületeket tartalmazó gyógyszerkészítmények | |
DE3062165D1 (en) | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo(4,3-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | |
BR9508608A (pt) | Composto formulação farmacêutica e processo para prevenir ou tratar arritmia | |
YU45726B (sh) | Postupak za dobijanje novih supstituisanih benzamida | |
DE69925472D1 (de) | Benzoheterocyclische distamycinderivate, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel | |
PT98747A (pt) | Processo para a preparacao de 6,7-dihidro-3-fenil-1-1,2-benzisoxazol-4(5h)-onase -ois e de composicoes farmaceuticas que os contem | |
MY132507A (en) | Process for substituted pyridines | |
GR78450B (sh) | ||
ES2000908A6 (es) | Procedimiento para la fabricacion de nuevos derivados de alquilmercaptofenil-1,3,4-oxadiazol | |
DE69402935D1 (de) | Substituierte arylalkylaminobenzyl-aminopropanamide, ihre herstellung und verwendung als antiepileptische, neuroprotektive und antidepressive mittel | |
ES8203901A1 (es) | Un procedimiento para la preparacion de benzamidas. | |
BR9408078A (pt) | Composto composição herbicida e processo para controlar vegetação indesejável | |
SE8501988L (sv) | Iminotiazolidinderivat | |
ES2132748T3 (es) | Herbicidas de carbamato. | |
ES472686A1 (es) | Procedimiento para preparar n-(4-pirazolidinil) benzamidas. | |
EA199800720A1 (ru) | Гетероциклические производные эрголина в качестве лигандов 5-htia рецептора | |
DK428087A (da) | Dihydropyridin-5-phosphonsyre-cyclopropylenester |