WO2018173480A1 - Dispositif d'administration de liquide médicinal - Google Patents

Dispositif d'administration de liquide médicinal Download PDF

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Publication number
WO2018173480A1
WO2018173480A1 PCT/JP2018/002621 JP2018002621W WO2018173480A1 WO 2018173480 A1 WO2018173480 A1 WO 2018173480A1 JP 2018002621 W JP2018002621 W JP 2018002621W WO 2018173480 A1 WO2018173480 A1 WO 2018173480A1
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WO
WIPO (PCT)
Prior art keywords
unit
drive
drive motor
rotation
chemical
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Application number
PCT/JP2018/002621
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English (en)
Japanese (ja)
Inventor
勝平 佐々木
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テルモ株式会社
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Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to JP2019507398A priority Critical patent/JPWO2018173480A1/ja
Publication of WO2018173480A1 publication Critical patent/WO2018173480A1/fr

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  • the present invention relates to a chemical solution administration device, and more particularly to a chemical solution administration device for performing continuous chemical solution administration such as an insulin pump.
  • a drug solution is continuously administered into a patient's body by subcutaneous injection or intravenous injection.
  • a treatment in which a minute amount of insulin is continuously infused into the body of the patient is performed.
  • a portable portable drug solution administration device (so-called insulin pump) fixed to the patient's body or clothes is used.
  • a syringe pump type device having a syringe for storing a chemical solution and a pusher driven inside the syringe has been proposed.
  • a pusher operation unit is connected to the pusher, and the driving force from the drive motor is transmitted to the pusher via this pusher operation unit (see, for example, Patent Document 1). Further, when the syringe is filled with the chemical solution, the connection between the pusher and the pusher operation unit is disconnected. And when a chemical
  • the drive speed of the drive motor is set to be slow in order to increase the torque of the drive motor in accordance with the maximum load value. Further, the drive speed of this drive motor was constant during preparation for drug solution administration. As a result, the conventional drug solution administration device has a problem that the time required for preparation for drug solution administration becomes long.
  • An object of the present invention is to provide a drug solution administration device that can reduce the time required for preparation for drug solution administration in consideration of the above-described problems.
  • a chemical liquid administration device of the present invention includes a chemical liquid storage unit filled with a chemical solution, a pusher member, a pusher operation unit, a drive unit, and rotation detection. Part and a control part.
  • the pusher member pushes out the chemical liquid filled in the chemical liquid storage section.
  • the pusher operation unit manipulates the movement of the pusher member.
  • the driving unit applies a driving force to the pusher operation unit.
  • the rotation detection unit detects the rotation of the drive unit.
  • the control unit controls driving of the driving unit.
  • the control unit detects a load applied to the drive unit based on the rotation signal of the drive unit detected by the rotation detection unit, and changes the torque generated by the drive unit.
  • the time required for preparation for drug solution administration can be shortened.
  • FIG. 1 is an exploded perspective view showing a drug solution administration device
  • FIG. 2 is a plan view showing the drug solution administration device.
  • the device shown in FIG. 1 is a portable insulin pump for continuously administering a drug solution into a patient's body, such as a patch-type or tube-type insulin pump, or other portable drug solution administration device.
  • the drug solution administration device 1 includes a drug solution administration unit 2, a cradle device 3 to which the drug solution administration unit 2 is detachably attached, and a connection port 6 to be attached to the cradle device 3.
  • the cradle device 3 is provided with a mounting portion 5 to which the connection port 6 is mounted.
  • the connection port 6 has a cannula 6a.
  • the connection port 6 is attached to the attachment portion 5 by sticking the cradle device 3 to the patient's skin and using a puncture mechanism (not shown).
  • a puncture mechanism not shown.
  • connection port 6 is accommodated in the rear surface storage portion of the casing 11 of the chemical solution administration unit 2 described later when the chemical solution administration unit 2 is installed in the state of being attached to the cradle device 3. And the connection port 6 is connected to the liquid feeding piping 19 of the chemical
  • the drug solution administration unit 2 includes a housing 11, a lid body 12, a drug solution storage unit 13, a transmission mechanism 14, a drive motor 15 that shows an example of a drive unit, a notification unit 16, and a power supply unit 17. ing.
  • the medicinal solution administration unit 2 includes a pusher member 18 that pushes out the medicinal solution filled in the medicinal solution storage unit 13, a liquid feeding pipe 19, a rotation detection unit 21, and a pusher operation unit 22 that operates the pusher member 18. ,have.
  • the housing 11 is formed in a hollow, substantially rectangular parallelepiped shape that is open on one side.
  • a first storage portion 11 a and a second storage portion 11 b are formed on the surface on the opening side of the housing 11, and a back surface storage portion is formed on the surface opposite to the front surface of the housing 11.
  • a drive motor 15, a power supply unit 17, a rotation detection unit 21, and a part of the transmission mechanism 14 are stored in the first storage unit 11a.
  • the second storage unit 11b stores the chemical solution storage unit 13, the pusher member 18, the pusher operation unit 22, and a part of the transmission mechanism 14.
  • the second storage part 11b is provided with a first bearing part 11c and a second bearing part 11d.
  • the 1st bearing part 11c and the 2nd bearing part 11d protrude toward the opening from the bottom face part of the 2nd accommodating part 11b.
  • a feed screw shaft 22b of a pusher operation unit 22 described later is rotatably supported by the first bearing unit 11c. Further, the shaft portion 23a of the operation gear 23 in the pusher operation portion 22 described later is rotatably supported by the second bearing portion 11d.
  • the lid 12 is formed in a substantially flat plate shape.
  • the lid 12 covers the first storage portion 11 a and the second storage portion 11 b formed on the surface of the housing 11 and closes the opening of the housing 11.
  • a transmission mechanism 14, a drive motor 15, a notification unit 16, a power supply unit 17, and a rotation detection unit 21 are attached to the lid 12.
  • the chemical solution storage unit 13 is formed in a cylindrical shape in which one end in the axial direction is closed and the other end in the axial direction is opened. A chemical solution is stored in the cylindrical hole 13 c of the chemical solution storage unit 13. A liquid feeding port 13 a and a filling port 13 b are formed at one end of the chemical liquid storage unit 13 in the axial direction.
  • the liquid supply port 13 a is connected to the liquid supply pipe 19.
  • the end of the liquid supply pipe 19 opposite to the liquid supply port 13 a is connected to the connection port 6.
  • the connection port 6 is punctured and placed in the patient's living body.
  • medical solution storage part 13 is discharged
  • a filling device (not shown) is connected to the filling port 13b. And a chemical
  • a pusher member 18 is slidably inserted into the cylindrical hole 13c of the chemical solution storage unit 13.
  • the pusher member 18 has a gasket 18a and a shaft portion 18b.
  • the gasket 18 a is slidably disposed in the cylindrical hole 13 c of the chemical liquid storage unit 13. The gasket 18a moves while being in liquid tight contact with the inner peripheral surface of the cylindrical hole 13c of the chemical solution storage unit 13.
  • the shape of the front end portion of the gasket 18a is formed corresponding to the shape of one end side in the axial direction of the cylindrical hole 13c of the chemical solution storage portion 13.
  • a shaft portion 18b is provided on the opposite side of the tip of the gasket 18a.
  • the shaft portion 18 b extends outward from an opening formed at the other end in the axial direction of the chemical solution storage portion 13.
  • a connecting portion 18c that is connected to a connecting nut 22c of a pusher operating portion 22 described later is provided at the end of the shaft portion 18b opposite to the gasket 18a.
  • the pusher operation unit 22 includes an operation gear 23, a feed screw shaft 22b, and a connection nut 22c.
  • the operation gear 23 meshes with a gear of the transmission mechanism 14 described later. Further, one end of the shaft portion 23a of the operation gear 23 is connected to an end portion in the axial direction of the feed screw shaft 22b. Furthermore, the other end of the shaft portion 23a of the operation gear 23 is rotatably supported by the second bearing portion 11d.
  • the feed screw shaft 22b is rotatably supported by the first bearing portion 11c. Further, the feed screw shaft 22b is arranged such that its axial direction is parallel to the shaft portion 18b. That is, the feed screw shaft 22b is arranged in parallel with the moving direction of the pusher member 18. A connecting nut 22c is screwed to the feed screw shaft 22b.
  • the connecting nut 22c When the connecting nut 22c is housed in the housing 11, the rotation of the feed screw shaft 22b around the circumferential direction is restricted. Thereby, when the operation gear 23 rotates and the feed screw shaft 22b rotates, the connecting nut 22c moves along the axial direction of the feed screw shaft 22b. After the connecting portion 18c of the pusher member 18 is engaged with the connecting nut 22c, the pusher member 18 moves along the axial direction of the feed screw shaft 22b together with the connecting nut 22c as the feed screw shaft 22b rotates. Move. Further, the drive force of the drive motor 15 is transmitted to the pusher operation unit 22 via the transmission mechanism 14.
  • the drive motor 15 for example, a stepping motor is applied.
  • the drive motor 15 is rotationally driven based on a drive signal from a calculation unit 101 (control unit) described later.
  • the drive motor 15 is connected to the electrode of the power supply unit 17 housed in the housing 11 and supplied with power in a state where the opening on the surface of the housing 11 is closed by the lid 12.
  • the drive shaft 15a of the drive motor 15 is provided with a rotation detector 21 that detects the rotation of the drive shaft 15a.
  • FIG. 3 is a perspective view showing the rotation detection unit 21.
  • the rotation detection unit 21 is a rotary encoder having a detection sensor 25 and a rotating body 26.
  • the rotator 26 includes a rotator body 26a fixed to the drive shaft 15a of the drive motor 15, three shielding plates 26b provided on the rotator body 26a, and a shaft provided on the rotator body 26a. 26d.
  • the rotating body main body 26a is formed in a substantially cylindrical shape.
  • the rotating body main body 26a rotates in synchronization with the rotation of the drive shaft 15a.
  • a shaft portion 26d protrudes on the opposite side of the rotating body main body portion 26a from the drive shaft 15a in the axial direction.
  • the shaft portion 26d is provided with a gear (not shown) and meshes with the gear of the transmission mechanism 14.
  • three shielding plates 26b are provided at equal angular intervals on the outer peripheral surface of the rotating body main body 26a. Therefore, three slits 26c are formed at equiangular intervals by the three shielding plates 26b on the periphery of the rotating body main body 26a.
  • the detection sensor 25 is arranged in the housing 11.
  • the optical sensor includes a light emitting unit 25a that emits light and a light receiving unit 25b that receives light emitted from the light emitting unit 25a.
  • the light emitted from the light emitting unit 25 a is blocked by the shielding plate 26 b of the rotating body 26 and passes through the slit 26 c of the rotating body 26.
  • the rotating body 26 is formed with three shielding plates 26b and three slits 26c. Therefore, when the drive shaft 15a of the drive motor 15 rotates once, that is, the rotator 26 rotates once, the light receiving portion 25b of the detection sensor 25 passes through the slit 26c and “dark” where light is blocked by the shielding plate 26b. A pulse signal in which one set of “light” for detecting light is repeated three times is detected (see FIG. 9). Thereby, the detection sensor 25 detects the rotation of the drive motor 15.
  • the number of shielding plates 26b is not limited to three, and two or four or more may be provided. For this reason, the pulse signal generated when the rotating body 26 makes one rotation changes as appropriate according to the number of shielding plates 26b and slits 26c.
  • the detection sensor 25 outputs the detected rotation information of the drive motor 15 to the calculation unit 101 (control unit) described later.
  • the transmission mechanism 14 is connected to the drive shaft 15 a of the drive motor 15 via the rotation detector 21.
  • the transmission mechanism 14 transmits the driving force (rotation) of the drive motor 15 to the pusher operation unit 22.
  • the transmission mechanism 14 is composed of a plurality of gears. When the drive motor 15 is driven, a plurality of gears constituting the transmission mechanism 14 rotate, and the driving force of the drive motor 15 is transmitted to the operation gear 23. Therefore, the pusher member 18 is operated, and the chemical liquid stored in the chemical liquid storage unit 13 is pushed out by the gasket 18a.
  • the notification unit 16 is connected to a calculation unit 101 described later.
  • the notification unit 16 is driven by an instruction from the calculation unit 101 (control unit) described later when a malfunction occurs in the drug solution administration device 1 or when an obstruction is detected, and outputs an alarm.
  • an alarm output from the notification unit 16 for example, vibration or sound may be emitted alone, or vibration or sound may be emitted in combination.
  • the power supply unit 17 is for supplying power to each component constituting the drug solution administration device 1.
  • the power supply unit 17 includes, for example, a battery 17a, a battery box that houses the battery 17a, and a switch that turns on / off the supply of power from the battery.
  • FIG. 4 is a block diagram showing a control system of the drug solution administration device 1.
  • the drug solution administration device 1 includes the drive motor 15, the rotation detection unit 21, the notification unit 16, and the power supply unit 17 described above.
  • the drug solution administration device 1 includes a calculation unit 101, an example of a control unit, a communication unit 103, a storage unit 104, and a date / time management unit 105.
  • the drive motor 15, the rotation detection unit 21, the notification unit 16, the power supply unit 17, the communication unit 103, the storage unit 104, and the date / time management unit 105 are connected to the calculation unit 101.
  • the rotation information of the drive motor 15 detected by the detection sensor 25 (see FIG. 3) of the rotation detection unit 21 is output to the calculation unit 101.
  • the driving of the drive motor 15 is controlled by the calculation unit 101.
  • the communication unit 103 is connected to a controller (not shown) that operates the drug administration device 1, an external portable information processing terminal, and a PC (personal computer) via a wired or wireless network.
  • the communication unit 103 receives operation information operated by a user via a controller (not shown), a portable information processing terminal, or the like, or measurement data measured by an external device. Then, the communication unit 103 outputs the received operation information and measurement data to the calculation unit 101.
  • the communication unit 103 is controlled by the calculation unit 101, so that the blockage information, the information about the amount of the chemical stored in the chemical storage unit 13, and various kinds of information about the chemical solution administration device 1 such as the administration pattern are not illustrated. Output to a controller or portable information processing terminal.
  • the storage unit 104 is a part that stores various data.
  • the storage unit 104 stores a control program for controlling a dosing profile indicating a dosing pattern for dispensing a medicinal solution, threshold data used in a medicinal solution dispensing preparatory operation for occlusion detection, and the like. Further, the storage unit 104 stores information received by the communication unit 103, rotation information of the drive motor 15 detected by the rotation detection unit 21, and the like. Then, the storage unit 104 outputs a control program stored in advance, rotation information received from another processing unit, and the like to the calculation unit 101.
  • the date / time management unit 105 is a program part for performing date / time management, and may be mounted on a general microcomputer, and outputs date / time information based on a command from the calculation unit 101.
  • the date and time management unit 105 outputs accurate date and time information by supplying power even when the power is off.
  • the arithmetic unit 101 is loaded with programs for controlling various devices such as the drive motor 15, the communication unit 103, the storage unit 104, and the date and time management unit 105. And the calculating part 101 controls various operation
  • the calculation unit 101 detects a load applied to the drive motor 15 based on the received rotation information.
  • the calculation unit 101 sets a drive signal for driving the drive motor 15 based on the rotation information.
  • the calculating part 101 drives the drive motor 15 based on the set drive signal.
  • the calculation unit 101 drives the drive motor 15 based on the administration profile indicating the administration pattern of the medicinal solution stored in the storage unit 104. Thereby, the user is administered with a drug solution based on a predetermined administration profile.
  • the arithmetic unit 101 includes, for example, a CPU (Central Processing Unit), a RAM (Random Access Memory), and a ROM (Read Only Memory) (not shown). ROM (Read Only Memory) may be the storage unit 104.
  • FIG. 5 is an explanatory diagram showing the relationship between the drive speed and torque of the drive motor 15 and the load.
  • FIG. 6 is an explanatory diagram showing a load applied to the drive motor in preparation for administration of a drug solution.
  • a predetermined amount of chemical solution is filled in the chemical solution storage unit 13 in advance.
  • the connecting nut 22 c of the pusher operating portion 22 is separated from the connecting portion 18 c of the pusher member 18. For this reason, the connection between the connection nut 22c and the connection portion 18c is removed.
  • the load (load) applied to the connection nut 22c is small, so the load applied to the drive motor 15 is also reduced.
  • the connecting nut 22c and the connecting portion 18c are connected. Then, the pusher member 18 is operated by the pusher operation unit 22, and the gasket 18 a is slid in the cylindrical hole 13 c of the chemical solution storage unit 13, so that the cylindrical hole 13 c, the liquid supply port 13 a and the liquid supply port of the chemical solution storage unit 13 are obtained. The air remaining in the pipe 19 is discharged from the liquid supply pipe 19.
  • the feed screw shaft 22b screwed with the connecting nut 22c receives a load opposite to the rotation direction via the connecting nut 22c.
  • a load in the direction opposite to the rotational direction is also applied to the operation gear 23 connected to the feed screw shaft 22b.
  • the load applied to the drive motor 15 via the transmission mechanism 14 increases, and the torque required for the drive motor 15 also increases.
  • FIG. 7 is a flowchart showing the chemical solution administration operation
  • FIG. 8 is an explanatory diagram showing the drive speed and torque of the drive motor in the chemical solution administration operation
  • FIG. 9 is a drive signal and rotation detection output to the drive motor by the arithmetic unit It is explanatory drawing which shows the relationship with the rotation signal which the part detected.
  • the calculation unit 101 sets the drive speed of the drive motor 15 (step S11).
  • the load applied to the drive motor 15 is small because the connection nut 22c is separated from the connection portion 18c. Therefore, as shown in FIG. 8, the calculation unit 101 sets the drive speed V of the drive motor 15 to the fastest first speed V 1 during the drug solution administration operation. In this case, the torque M of the drive motor 15, a first torque M 1.
  • the calculation unit 101 outputs a drive signal (motor drive pulse) corresponding to the drive speed (first speed V 1 ) set in the process of step S11 to the drive motor 15 to drive the drive motor 15 (step S12).
  • the drive signal output from the calculation unit 101 to the drive motor 15 is a signal for rotating the drive shaft 15a once in T1 seconds, as shown in FIG.
  • the drive motor 15 is driven, and the driving force is transmitted to the pusher operation unit 22 via the transmission mechanism 14.
  • the connecting nut 22c moves along the axial direction of the feed screw shaft 22b and approaches the connecting portion 18c. Further, when the drive shaft 15a of the drive motor 15 rotates, the rotating body 26 of the rotation detection unit 21 also rotates.
  • the calculation unit 101 determines whether or not a stop command has been input from the user via the communication unit 103 (step S13).
  • a stop command has been input from the user via the communication unit 103.
  • step S13 when it is determined that a stop command has not been input (NO determination in step S13), the calculation unit 101 determines whether a load is detected based on the rotation signal from the rotation detection unit 21. Judgment is made (step S14).
  • a rotation signal (rotation detection) detected by the rotation detection unit 21 in one pulse (T1 second) of the drive signal output from the calculation unit 101.
  • Part pulse is a signal in which “bright” and “dark” are repeated six times.
  • the drive motor 15 does not rotate normally. Therefore, the repetition pattern of “bright” and “dark” of the rotation signal (rotation detection unit pulse) detected by the rotation detection unit 21 changes in one pulse (T1 second) of the drive signal output by the calculation unit 101 (FIG. In the example shown in FIG. 9, “bright” is 2 times and “dark” is 4 times). Then, the calculation unit 101 determines that a load has been detected when a rotation signal in which a repeated pattern of “bright” and “dark” is changed is received.
  • step S14 If it is determined in step S14 that the load is not detected (NO determination in step S14), the calculation unit 101 returns to step S12 and drives the drive motor 15 without changing the drive speed V. .
  • step S14 If it is determined in step S14 that a load has been detected (YES determination in step S14), the operation unit 101 returns to step S11 and sets the drive speed V again.
  • the calculation unit 101 sets the second speed V 2 that is slower than the first speed V 1 . In this case, the torque M of the drive motor 15, the second the torque M 2 greater than the first torque M1.
  • the calculation unit 101 a drive signal corresponding to the driving speed set in the process of step S11 (second velocity V 2) is outputted to the drive motor 15 to drive the drive motor 15 (step S12).
  • the drive signal output from the calculation unit 101 to the drive motor 15 is a signal for rotating the drive shaft 15a once in T2 seconds longer than T1 seconds.
  • the voltage value or a current value applied to the drive motor 15 is the same value as the first velocity V 1.
  • the driving speed V of the drive motor 15, than the second speed V 2 is set to a slow third velocity V 3.
  • the drive speed V of the drive motor 15 is set as shown in FIG.
  • the fourth speed V 4 is set slower than the third speed V 3 .
  • the torque M of the drive motor 15 becomes the fourth torque M 4 that is larger than the third torque M 3 .
  • the drug solution administration device 1 of the present example changes the drive speed V stepwise according to the load applied to the drive motor 15.
  • the change in the driving speed V of the drive motor 15 is not limited to four stages, but is changed according to the load applied to the drive motor 15 during the preparation for drug administration. Therefore, the drive speed V of the drive motor 15 may change to three steps or less depending on the load applied to the drive motor 15, or may change to five steps or more.
  • step S13 a stop command is input from the user in the process of step S13.
  • the arithmetic unit 101 stops driving of the drive motor 15 (step S15).
  • step S15 the chemical
  • the drive speed of the drive motor 15 is set based on the rotation signal detected by the rotation detector 21.
  • the load applied to the drive motor 15 is relatively small, and the initial drive speed V of the drive motor 15 that starts the drug solution preparation operation can be increased.
  • the drive motor 15 can generate torque corresponding to the load by decreasing the drive speed V stepwise. Thereby, it is possible to prevent the drive motor 15 from stopping against the user's intention due to the applied load.
  • an insulin pump that administers insulin is applied as the drug solution administration device.
  • the present invention is not limited to this.
  • various other drug solutions such as analgesics, anticancer therapeutic agents, HIV drugs, iron chelating agents, pulmonary hypertension therapeutic agents and the like may be used.
  • the example in which the torque M generated in the drive motor 15 is increased by making the voltage value or current value applied to the drive motor 15 constant and slowing the drive speed V has been described. It is not limited to this.
  • a booster circuit may be provided in the drive motor, and the voltage value or current value applied to the drive motor may be varied.
  • the torque M generated in the drive motor can be increased by increasing the voltage value or current value applied to the drive motor while keeping the drive speed V of the drive motor constant. As a result, it is possible to further reduce the time required for preparation for administration of the drug solution.
  • SYMBOLS 1 Chemical solution administration apparatus, 2 ... Chemical solution administration part, 3 ... Cradle apparatus, 5 ... Mounting part, 6 ... Connection port, 6a ... Cannula, 11 ... Housing
  • Rotation detection portion 22 ... Pusher operation portion, 22b ... Feed screw shaft, 22c ... Connection nut, 23 ... Operation gear, 25 ... Detection sensor, 25a ... Light emitting part, 25b ... Light receiving part, 26 ... Rotating body, 26a ... Rotating body main body part, 26b ... Shielding plate, 26c ... Slit, 101 ... Calculation part (control part), 104 ... Storage part, M ... Torque, V ... drive speed , V 1 ... first velocity, V 2 ... second velocity, V 3 ... third velocity, V 4 ... 4 Speed

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  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Ce dispositif d'administration de liquide médicinal est pourvu d'une unité de stockage de liquide médicinal remplie d'un liquide médicinal, d'un élément piston, d'une unité d'actionnement de piston, d'une unité d'entraînement, d'une unité de détection de rotation et d'une unité de commande. L'unité de détection de rotation détecte la rotation de l'unité d'entraînement. L'unité de commande détecte une charge appliquée à l'unité d'entraînement sur la base d'un signal de rotation d'unité d'entraînement détecté par l'unité de détection de rotation, et amène un couple généré par l'unité d'entraînement à être changé.
PCT/JP2018/002621 2017-03-23 2018-01-29 Dispositif d'administration de liquide médicinal WO2018173480A1 (fr)

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JP2017056944 2017-03-23

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WO2018173480A1 true WO2018173480A1 (fr) 2018-09-27

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
JP2020130222A (ja) * 2019-02-13 2020-08-31 テルモ株式会社 薬液投与装置

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JP2007511252A (ja) * 2003-06-09 2007-05-10 ニプロ ダイアビティーズ システムズ，インコーポレイテッド 注入ポンプにおけるカップリングシステム
JP2011520569A (ja) * 2008-05-20 2011-07-21 アヴァント・メディカル・コーポレーション オートインジェクタシステム
JP2015514527A (ja) * 2012-04-25 2015-05-21 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 電気機械デバイスおよび動き検出器を備える装置ならびに装置を動作させるための方法

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JP2006522658A (ja) * 2003-04-08 2006-10-05 メドラッド インコーポレーテッド 流体運搬システム、流体運搬装置、及び危険性流体を搬送する方法
US8430849B2 (en) * 2010-09-24 2013-04-30 Perqflo, Llc Infusion pumps and plunger pusher position-responsive cartridge lock for infusion pumps
JP2013192850A (ja) * 2012-03-22 2013-09-30 Terumo Corp 薬液投与装置

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Publication number Priority date Publication date Assignee Title
JP2007511252A (ja) * 2003-06-09 2007-05-10 ニプロ ダイアビティーズ システムズ，インコーポレイテッド 注入ポンプにおけるカップリングシステム
JP2011520569A (ja) * 2008-05-20 2011-07-21 アヴァント・メディカル・コーポレーション オートインジェクタシステム
JP2015514527A (ja) * 2012-04-25 2015-05-21 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 電気機械デバイスおよび動き検出器を備える装置ならびに装置を動作させるための方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020130222A (ja) * 2019-02-13 2020-08-31 テルモ株式会社 薬液投与装置
JP7159076B2 (ja) 2019-02-13 2022-10-24 テルモ株式会社 薬液投与装置

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