WO2010058406A1 - Stent externe - Google Patents
Stent externe Download PDFInfo
- Publication number
- WO2010058406A1 WO2010058406A1 PCT/IL2009/001105 IL2009001105W WO2010058406A1 WO 2010058406 A1 WO2010058406 A1 WO 2010058406A1 IL 2009001105 W IL2009001105 W IL 2009001105W WO 2010058406 A1 WO2010058406 A1 WO 2010058406A1
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- WIPO (PCT)
- Prior art keywords
- support
- vein
- diameter
- optionally
- vein support
- Prior art date
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Classifications
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/064—Blood vessels with special features to facilitate anastomotic coupling
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
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- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
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- A—HUMAN NECESSITIES
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1107—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis for blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1135—End-to-side connections, e.g. T- or Y-connections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
Definitions
- a vein support for use with a vein to help provide a desired blood flow between a first point in a vascular system of a patient and a second point in the vascular system by incorporation of the vein into the vascular system
- the vein support comprising an elongate body having a first end and a second end with a channel therebetween, the elongate body having a relaxed pre-deformation configuration, the channel sized to freely receive the vein when the body is in the pre-deformation configuration so that an axis of the channel extends along an axis of the vein; and the body being manually manipulatable from the pre-deformation configuration to a relaxed post-deformation configuration selected in response to the vascular system, the channel in the post-deformation configuration supporting receiving the vein therein so as to inhibit tissue-response induced occlusion of the desired flow.
- FIGs. 7 A - 7C schematically illustrate a method of using a vein support in a vein- based bypass operation, in accordance with an embodiment of the present invention
- FIGs. 1OA - 1OC schematically illustrate exemplary coverings and/or sleeves applied to an end portion of a vein support, in accordance with some embodiments of the present invention
- FIGs.17A and 17B depict photographs of a portion of an extended support substantially resembling that used in a CABG procedure, and an enlarged view of a section of the support, respectively, in accordance with some embodiments of the present invention.
- the formable tubular support is provided as a mesh that includes at least one plastically deformable thread.
- the mesh may be braided, woven, knitted, pressed and/or in any other known construction and/or any combination thereof.
- the at least one thread may be a wire, a yarn, a filament a fiber, a rod, a stripe or any other longitudinal element having a relatively large length- to-diameter/width ratio; and may be made of any plastically deformable material, including but not limited to metal, polymers, composites, glued bundles, or any combination thereof.
- specific braid pattern and/or threads parameters are chosen for a tubular blood vessel support to allow at least one of the following end points:
- the formable support is provided as a tube and can only be pulled over (or under) the tubular bodily vessel or graft having at least one free end (i.e., prior to anastomosing).
- the formable support is opened along its length and can be closed over the bodily vessel/graft (e.g., similarly to a bracelet-cuff) using closing means, such as clips, hooks, adhesives, sewing means, zipping means, and/or may be deformablely closed by applying enough force.
- the formable tubular support is provided as plurality of coupling members or "building blocks" to modularly form a shaped tubular implant in-situ.
- the coupling members are provided in different shapes, e.g., bent, curved and/or maintain any other non-tubular shapes, some may vary in diameter.
- the operator may couple at least two coupling members over a target vessel/graft periphery and may choose specific shaped coupling members in order to set a specific chosen course.
- some or any of the coupling members may be rigid, elastic and/or plastic but may not be bounded to include plastically deformable members as previously described.
- springback from stretching support 100 may range from 0.5% - 50%, for example, 0.5% - 5%, 2% - 10%, 2% - 20%, 2% - 30%, 2% - 40%
- springback in radial elasticity may range from 2% to 50%, for example, 2% - 5%, 2% - 10%, 2% - 20%, 2% - 30%, 2% - 40%
- plastically deformable fiber 102 may have an average diameter in the range of 20 to l,000 ⁇ m, optionally between 50 to 200 ⁇ m, optionally approximately 75 ⁇ m, optionally approximately 150 ⁇ m.
- support 500 may be a braided support including at least one plastically deformable strut 502.
- struts 502 may define openings 506 that can be of any shape, including but not limited to polygonal shapes, optionally quadrangular.
- struts 502 may include similar plastically deformable characteristics to those of fiber 102 shown in Fig. 1.
- support 500 may include any other type of support, including but not limited to bare metal/polymeric support, drug eluting support that may or may not be produced by one of more of the followings methods; laser cutting, EDM, chemical etching, micromachining, photo-etching and water-jet laser cutting.
- At least one of the anastomosed ends and/or its close-by surroundings are covered and/or supported by at least part of support 700 (not shown).
- support 700 can then be manipulated to adjust a chosen contour to at least part of the covered segment of graft 721.
- support 700 fully stretched is firm enough to substantially maintain the applied contour either permanently or for a prolonged period of time after end of the surgical procedure, optionally over 1 week, optionally over 1 month, optionally over 1 year, optionally over 10 years, or higher or lesser or intermediate.
- vein support 1200 may be the same as vein support 100 shown in Fig. 1.
- vein support 1200 may be the same as that shown in Figs. 2, 3, 4, 5A, 7A, 8A, or 9B at 200, 300, 400, 500, 700, 800 or 900, respectively.
- extension 1301 is added to support 1300 as an elastic end portion specifically designed to fit over anastomosis area.
- Extension 1301 is optionally connected to an end portion of support 1300 only after the latter has been mounted and/or stretched and/or shaped to fit a target vessel.
- Extension 1301 may be made from a flat mesh including elastic fibers 1304 as shown in Fig. 13A which is cut at one end so that, when the mesh is rolled to form the extension, on angled opening 1301B includes the angle 0 relative to an axis 1308 of the support.
- Photographs have been included as Fig. 17A and Fig. 17B depicting a portion of an exemplary extended support and an enlarged view of a section of support, respectively, in accordance with some embodiments of the present invention.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Prostheses (AREA)
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09796098.3A EP2361059B1 (fr) | 2008-11-24 | 2009-11-24 | Stent externe |
DK09796098.3T DK2361059T3 (da) | 2008-11-24 | 2009-11-24 | Ekstern stent |
CA2743803A CA2743803C (fr) | 2008-11-24 | 2009-11-24 | Stent externe |
US13/130,760 US8734503B2 (en) | 2008-11-24 | 2009-11-24 | External stent |
AU2009318772A AU2009318772B2 (en) | 2008-11-24 | 2009-11-24 | External stent |
JP2011537010A JP5855460B2 (ja) | 2008-11-24 | 2009-11-24 | 外部ステント |
CN200980155497.1A CN102307542B (zh) | 2008-11-24 | 2009-11-24 | 外部支架 |
ZA2011/03750A ZA201103750B (en) | 2008-11-24 | 2011-05-23 | External stent |
IL213111A IL213111A (en) | 2008-11-24 | 2011-05-24 | External support |
US14/287,030 US9265632B2 (en) | 2008-11-24 | 2014-05-25 | Methods of supporting a vein |
US15/008,929 US9949852B2 (en) | 2008-11-24 | 2016-01-28 | Implant for supporting bodily conduits such as blood vessels or/and grafted vessels |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
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US19339808P | 2008-11-24 | 2008-11-24 | |
US61/193,398 | 2008-11-24 | ||
US18604609P | 2009-06-11 | 2009-06-11 | |
US61/186,046 | 2009-06-11 | ||
US24413809P | 2009-09-21 | 2009-09-21 | |
US61/244,138 | 2009-09-21 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
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US13/130,760 A-371-Of-International US8734503B2 (en) | 2008-11-24 | 2009-11-24 | External stent |
US14/287,030 Continuation US9265632B2 (en) | 2008-11-24 | 2014-05-25 | Methods of supporting a vein |
Publications (1)
Publication Number | Publication Date |
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WO2010058406A1 true WO2010058406A1 (fr) | 2010-05-27 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/IL2009/001105 WO2010058406A1 (fr) | 2008-11-24 | 2009-11-24 | Stent externe |
Country Status (10)
Country | Link |
---|---|
US (3) | US8734503B2 (fr) |
EP (1) | EP2361059B1 (fr) |
JP (1) | JP5855460B2 (fr) |
CN (1) | CN102307542B (fr) |
AU (1) | AU2009318772B2 (fr) |
CA (1) | CA2743803C (fr) |
DK (1) | DK2361059T3 (fr) |
IL (1) | IL213111A (fr) |
WO (1) | WO2010058406A1 (fr) |
ZA (1) | ZA201103750B (fr) |
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- 2009-11-24 CN CN200980155497.1A patent/CN102307542B/zh active Active
- 2009-11-24 WO PCT/IL2009/001105 patent/WO2010058406A1/fr active Application Filing
- 2009-11-24 US US13/130,760 patent/US8734503B2/en active Active
- 2009-11-24 JP JP2011537010A patent/JP5855460B2/ja active Active
- 2009-11-24 CA CA2743803A patent/CA2743803C/fr active Active
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US8734503B2 (en) | 2008-11-24 | 2014-05-27 | Vascular Graft Solutions Ltd. | External stent |
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US9949852B2 (en) | 2008-11-24 | 2018-04-24 | Vascular Graft Solutions Ltd. | Implant for supporting bodily conduits such as blood vessels or/and grafted vessels |
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WO2012143922A1 (fr) | 2011-04-18 | 2012-10-26 | Vascular Graft Solutions Ltd | Support externe pour vaisseaux corporels allongés |
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US9579224B2 (en) * | 2011-07-25 | 2017-02-28 | Neograft Technologies, Inc. | Vessel remodeling methods and devices for use in a graft device |
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CN109833521A (zh) * | 2017-11-29 | 2019-06-04 | 郑州大学 | 一种制备人工血管的方法及装置 |
Also Published As
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US9949852B2 (en) | 2018-04-24 |
AU2009318772A1 (en) | 2010-05-27 |
AU2009318772A2 (en) | 2011-06-30 |
US20160143754A1 (en) | 2016-05-26 |
JP5855460B2 (ja) | 2016-02-09 |
IL213111A0 (en) | 2011-07-31 |
US20110230955A1 (en) | 2011-09-22 |
CN102307542B (zh) | 2016-05-11 |
AU2009318772B2 (en) | 2016-05-19 |
US20140257462A1 (en) | 2014-09-11 |
EP2361059B1 (fr) | 2014-05-14 |
ZA201103750B (en) | 2012-01-25 |
IL213111A (en) | 2015-05-31 |
US8734503B2 (en) | 2014-05-27 |
CA2743803A1 (fr) | 2010-05-27 |
EP2361059A1 (fr) | 2011-08-31 |
DK2361059T3 (da) | 2014-08-18 |
CN102307542A (zh) | 2012-01-04 |
JP2012509703A (ja) | 2012-04-26 |
CA2743803C (fr) | 2016-12-13 |
US9265632B2 (en) | 2016-02-23 |
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