WO2009071804A3 - Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique - Google Patents

Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique Download PDF

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Publication number
WO2009071804A3
WO2009071804A3 PCT/FR2008/052088 FR2008052088W WO2009071804A3 WO 2009071804 A3 WO2009071804 A3 WO 2009071804A3 FR 2008052088 W FR2008052088 W FR 2008052088W WO 2009071804 A3 WO2009071804 A3 WO 2009071804A3
Authority
WO
WIPO (PCT)
Prior art keywords
phytoecdysones
metabolic syndrome
composition
acting
preparation
Prior art date
Application number
PCT/FR2008/052088
Other languages
English (en)
Other versions
WO2009071804A2 (fr
Inventor
Stanislas Veillet
René LAFONT
Original Assignee
Institut Biophytis Sas
Universite Pierre Et Marie Curie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Biophytis Sas, Universite Pierre Et Marie Curie filed Critical Institut Biophytis Sas
Priority to CN200880118514.XA priority Critical patent/CN102231986B/zh
Priority to CA2706821A priority patent/CA2706821A1/fr
Priority to US12/745,315 priority patent/US8236359B2/en
Priority to BRPI0820455A priority patent/BRPI0820455B8/pt
Priority to RU2010126625/15A priority patent/RU2491083C2/ru
Priority to PL08856497T priority patent/PL2217255T3/pl
Priority to EP08856497.6A priority patent/EP2217255B1/fr
Priority to AU2008332981A priority patent/AU2008332981B2/en
Priority to ES08856497T priority patent/ES2747932T3/es
Priority to JP2010535430A priority patent/JP2011504921A/ja
Publication of WO2009071804A2 publication Critical patent/WO2009071804A2/fr
Publication of WO2009071804A3 publication Critical patent/WO2009071804A3/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/168Steroids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/184Hormones
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Steroid Compounds (AREA)

Abstract

Pour diminuer les effets négatifs du syndrome métabolique sur l'organisme des mammifères, il est prévu dans l'invention d'utiliser des phytoecdysones, de manière à diminuer la masse grasse chez un individu notamment en surpoids. Les phytoecdysones sont avantageusement incorporées dans une composition alimentaire. Selon l'invention, les phytoecdysones peuvent être issues de plantes alimentaires, telles que le quinoa.
PCT/FR2008/052088 2007-11-30 2008-11-19 Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique WO2009071804A2 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
CN200880118514.XA CN102231986B (zh) 2007-11-30 2008-11-19 植物蜕皮激素在制备对代谢综合征有效的组合物中的用途
CA2706821A CA2706821A1 (fr) 2007-11-30 2008-11-19 Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique
US12/745,315 US8236359B2 (en) 2007-11-30 2008-11-19 Use of phytoecdysones in the preparation of a composition for acting on the metabolic syndrome
BRPI0820455A BRPI0820455B8 (pt) 2007-11-30 2008-11-19 composição para agir sobre a síndrome metabólica
RU2010126625/15A RU2491083C2 (ru) 2007-11-30 2008-11-19 Применение фитоэкдизонов и получение композиции для воздействия на метаболический синдром
PL08856497T PL2217255T3 (pl) 2007-11-30 2008-11-19 Zastosowanie fitoekdyzonów do wytwarzania kompozycji do wpływania na zespół metaboliczny
EP08856497.6A EP2217255B1 (fr) 2007-11-30 2008-11-19 Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique
AU2008332981A AU2008332981B2 (en) 2007-11-30 2008-11-19 Use of phytoecdysones in the preparation of a composition for acting on metabolic syndrome
ES08856497T ES2747932T3 (es) 2007-11-30 2008-11-19 Uso de fitoecdisonas en la preparación de una composición para actuar sobre el síndrome metabólico
JP2010535430A JP2011504921A (ja) 2007-11-30 2008-11-19 メタボリック症候群に作用する組成物の調製における植物エクジソンの使用

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0759478 2007-11-30
FR0759478A FR2924346B1 (fr) 2007-11-30 2007-11-30 Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique.

Publications (2)

Publication Number Publication Date
WO2009071804A2 WO2009071804A2 (fr) 2009-06-11
WO2009071804A3 true WO2009071804A3 (fr) 2010-04-22

Family

ID=39473912

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/052088 WO2009071804A2 (fr) 2007-11-30 2008-11-19 Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique

Country Status (12)

Country Link
US (1) US8236359B2 (fr)
EP (1) EP2217255B1 (fr)
JP (1) JP2011504921A (fr)
CN (1) CN102231986B (fr)
AU (1) AU2008332981B2 (fr)
BR (1) BRPI0820455B8 (fr)
CA (1) CA2706821A1 (fr)
ES (1) ES2747932T3 (fr)
FR (1) FR2924346B1 (fr)
PL (1) PL2217255T3 (fr)
RU (1) RU2491083C2 (fr)
WO (1) WO2009071804A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2982489B1 (fr) * 2011-11-10 2013-12-27 Inst Biophytis Sas Phytoecdysones pour leur utilisation dans la stabilisation du poids apres un regime amaigrissant
FR2983733B1 (fr) * 2011-12-13 2017-12-22 Inst Biophytis Sas Phytoecdysones pour leur utilisation dans l'amelioration de la qualite musculaire de mammiferes obeses et/ou sarcopeniques
US10441594B2 (en) * 2013-12-06 2019-10-15 Rutgers, The State University Of New Jersey Methods of making quinoa leachates and uses thereof
CN103837615B (zh) * 2014-02-15 2015-05-20 青岛农业大学 一种应用高效液相色谱法同时测定植物蜕皮激素类物质的方法
FR3078252B1 (fr) * 2018-02-28 2020-08-14 Biophytis Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation
RU2764439C1 (ru) * 2021-04-09 2022-01-17 Федеральное государственное бюджетное учреждение науки "Федеральный исследовательский центр питания, биотехнологии и безопасности пищи" Способ получения экстракта из зерен киноа, обогащенного фитоэкдистероидами

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04124135A (ja) * 1990-09-14 1992-04-24 Veritas:Kk 抗糖尿病薬
CN1557324A (zh) * 2004-01-13 2004-12-29 秋 陈 蜕皮甾酮在制备治疗胰岛素抵抗药物中的应用
GB2420066A (en) * 2004-11-23 2006-05-17 Nor Feed As Feed additive derived from plant material originating from quinoa (Chenopodium quinoa)

Family Cites Families (11)

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JPS632928A (ja) * 1986-06-20 1988-01-07 Japan Bio Kenkyusho:Kk 鎮痛剤
JP3862295B2 (ja) * 1993-09-30 2006-12-27 独立行政法人理化学研究所 抗肥満剤
JP4676040B2 (ja) * 1997-07-31 2011-04-27 株式会社林原生物化学研究所 組成物
JP3873097B2 (ja) * 1997-11-06 2007-01-24 独立行政法人理化学研究所 抗肥満剤及び脂質代謝改善剤
JP3858055B2 (ja) * 2000-02-29 2006-12-13 独立行政法人理化学研究所 抗肥満剤及び脂質代謝改善剤
CN1280010A (zh) * 2000-06-12 2001-01-17 昆明制药股份有限公司 一种治疗糖尿病的口服药物及其生产方法
WO2004016092A1 (fr) * 2002-08-14 2004-02-26 Bionutrigen Co., Ltd Poudre ou extraits de feuilles vegetales presentant des effets anti-obesite et aliments anti-obesite comprenant ceux-ci
JP4124135B2 (ja) 2004-02-13 2008-07-23 株式会社デンソー ガスセンサ
RU2290185C1 (ru) * 2005-07-26 2006-12-27 Дмитрий Николаевич Мясников Композиция для нормализации липидного обмена и снижения массы тела и способ её получения
US8377915B2 (en) * 2006-05-09 2013-02-19 Rutgers, The State University Of New Jersey Methods for treating or preventing disorders using ecdysteroid compositions
CN101011436A (zh) * 2007-01-20 2007-08-08 苏州大学 牛膝总甾酮的医药用途

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04124135A (ja) * 1990-09-14 1992-04-24 Veritas:Kk 抗糖尿病薬
CN1557324A (zh) * 2004-01-13 2004-12-29 秋 陈 蜕皮甾酮在制备治疗胰岛素抵抗药物中的应用
GB2420066A (en) * 2004-11-23 2006-05-17 Nor Feed As Feed additive derived from plant material originating from quinoa (Chenopodium quinoa)

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* Cited by examiner, † Cited by third party
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CATALAN R E ET AL: "Alterations in rat lipid metabolism following ecdysterone treatment", COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. B. COMPARATIVEBIOCHEMISTRY, PERGAMON PRESS, LONDON, GB, vol. 81, no. 3, 1 January 1985 (1985-01-01), pages 771 - 775, XP023529585, ISSN: 0305-0491, [retrieved on 19850101] *
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Also Published As

Publication number Publication date
BRPI0820455A2 (pt) 2015-09-29
WO2009071804A2 (fr) 2009-06-11
BRPI0820455B1 (pt) 2020-09-24
FR2924346A1 (fr) 2009-06-05
AU2008332981A1 (en) 2009-06-11
RU2010126625A (ru) 2012-01-10
CN102231986B (zh) 2014-01-22
ES2747932T3 (es) 2020-03-12
FR2924346B1 (fr) 2010-02-19
CN102231986A (zh) 2011-11-02
US8236359B2 (en) 2012-08-07
EP2217255A2 (fr) 2010-08-18
PL2217255T3 (pl) 2020-06-01
US20110033561A1 (en) 2011-02-10
BRPI0820455B8 (pt) 2021-05-25
AU2008332981B2 (en) 2014-06-12
RU2491083C2 (ru) 2013-08-27
EP2217255B1 (fr) 2019-07-03
JP2011504921A (ja) 2011-02-17
CA2706821A1 (fr) 2009-06-11
AU2008332981A2 (en) 2010-07-22

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