WO2009069417A1 - 血液流動性計測システム及び血液流動性計測方法 - Google Patents

血液流動性計測システム及び血液流動性計測方法 Download PDF

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Publication number
WO2009069417A1
WO2009069417A1 PCT/JP2008/069528 JP2008069528W WO2009069417A1 WO 2009069417 A1 WO2009069417 A1 WO 2009069417A1 JP 2008069528 W JP2008069528 W JP 2008069528W WO 2009069417 A1 WO2009069417 A1 WO 2009069417A1
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WIPO (PCT)
Prior art keywords
blood fluidity
blood
fluidity measurement
measurement system
channel
Prior art date
Application number
PCT/JP2008/069528
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English (en)
French (fr)
Inventor
Shuji Ichitani
Masaaki Takama
Takanori Murayama
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Konica Minolta Opto, Inc.
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Publication date
Application filed by Konica Minolta Opto, Inc. filed Critical Konica Minolta Opto, Inc.
Priority to CN2008801176827A priority Critical patent/CN101874200B/zh
Priority to EP08853723.8A priority patent/EP2219020A4/en
Priority to US12/744,638 priority patent/US20100260391A1/en
Priority to JP2009543725A priority patent/JP5146462B2/ja
Publication of WO2009069417A1 publication Critical patent/WO2009069417A1/ja

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/02Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
    • G01N11/04Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
    • G01N11/06Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by timing the outflow of a known quantity
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/02Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
    • G01N11/04Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
    • G01N11/08Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by measuring pressure required to produce a known flow
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N2011/006Determining flow properties indirectly by measuring other parameters of the system
    • G01N2011/008Determining flow properties indirectly by measuring other parameters of the system optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0092Monitoring flocculation or agglomeration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1027Determining speed or velocity of a particle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493Particle size
    • G01N2015/1495Deformation of particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10016Video; Image sequence
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30101Blood vessel; Artery; Vein; Vascular
    • G06T2207/30104Vascular flow; Blood flow; Perfusion

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

 短時間で血液の流動性を計測することを課題とする。 そのためには、血液を流路へ流して当該血液の流動性を計測する血液流動性計測システム1であって、流路での血液の流れを撮影するTVカメラ6と、TVカメラ6によって得られた画像から、流路における血流状態を、血液の流動性として検出する画像処理部7とを備える構成とする。
PCT/JP2008/069528 2007-11-28 2008-10-28 血液流動性計測システム及び血液流動性計測方法 WO2009069417A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN2008801176827A CN101874200B (zh) 2007-11-28 2008-10-28 血液流动性测量***及血液流动性测量方法
EP08853723.8A EP2219020A4 (en) 2007-11-28 2008-10-28 SYSTEM AND METHOD FOR MEASURING THE BLOOD-FLOWING CAPACITY
US12/744,638 US20100260391A1 (en) 2007-11-28 2008-10-28 Blood fluidity measurement system and blood fluidity measurement method
JP2009543725A JP5146462B2 (ja) 2007-11-28 2008-10-28 血液流動性計測システム

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-306969 2007-11-28
JP2007306969 2007-11-28
JP2008-175489 2008-07-04
JP2008175489 2008-07-04

Publications (1)

Publication Number Publication Date
WO2009069417A1 true WO2009069417A1 (ja) 2009-06-04

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PCT/JP2008/069528 WO2009069417A1 (ja) 2007-11-28 2008-10-28 血液流動性計測システム及び血液流動性計測方法

Country Status (5)

Country Link
US (1) US20100260391A1 (ja)
EP (1) EP2219020A4 (ja)
JP (1) JP5146462B2 (ja)
CN (1) CN101874200B (ja)
WO (1) WO2009069417A1 (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010137471A1 (ja) * 2009-05-29 2010-12-02 コニカミノルタオプト株式会社 凝集量計測装置及び凝集量計測方法
WO2011010570A1 (ja) * 2009-07-24 2011-01-27 コニカミノルタオプト株式会社 凝集量計測装置及び凝集量計測方法
WO2011010569A1 (ja) * 2009-07-24 2011-01-27 コニカミノルタオプト株式会社 マイクロチップ及び速度計測装置
WO2011065177A1 (ja) * 2009-11-26 2011-06-03 コニカミノルタオプト株式会社 血球軌跡表示装置
JP2012098036A (ja) * 2010-10-29 2012-05-24 Sony Corp 試料流入装置、試料流入チップ及び試料流入方法
JP2017504007A (ja) * 2013-12-09 2017-02-02 テキサス テック ユニヴァーシティー システムTexas Tech University System 流体の高スループット分析のためのスマートフォンベースの多重化粘度計
CN112304877A (zh) * 2020-11-02 2021-02-02 南京润太医学检验实验室有限公司 一种用于血液流变检测的光电装置

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ITNA20100051A1 (it) * 2010-10-25 2012-04-26 Stefano Guido Microdispositivo per la misura delle proprietà viscoelastiche di globuli rossi
ITNA20110033A1 (it) * 2011-07-29 2013-01-30 Stefano Guido Misura dell' aggregabilità eritrocitaria in flusso in microcapillari
FR2991457B1 (fr) 2012-06-01 2014-07-18 Commissariat Energie Atomique Procede et systeme de caracterisation de la vitesse de deplacement de particules contenues dans un liquide, telles que des particules sanguines
US9506935B2 (en) 2012-06-01 2016-11-29 Commissariat à l'énergie atomique et aux énergies alternatives Method and system for estimating the quantity of an analyte contained in a liquid
WO2017021971A1 (en) * 2015-08-05 2017-02-09 Art Healthcare Ltd. Point of care urine analyzer
GB2555870A (en) * 2016-11-15 2018-05-16 Haemair Ltd Rheometer and method for the use thereof
US11543420B2 (en) * 2018-01-16 2023-01-03 Apel Co., Ltd Blood clotting time measurement cartridge and blood clotting time measuring device
CN109657724B (zh) * 2018-12-21 2021-08-03 浙江中烟工业有限责任公司 一种基于并行计算的沟槽滤棒特征参数快速计算方法

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TSUTOMU TAJIKAWA ET AL.: "Micro-channel Array o Mochiita Mosaikekkanchu no Sekkekkyu no Kyodo to Henkeino ni Kansuru Seitaigai Jikken", THE VISUALIZATION SOCIETY OF JAPAN RONBUNSHU, vol. 25, no. 12, 2005, pages 84 - 91, XP008135842 *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010137471A1 (ja) * 2009-05-29 2010-12-02 コニカミノルタオプト株式会社 凝集量計測装置及び凝集量計測方法
WO2011010570A1 (ja) * 2009-07-24 2011-01-27 コニカミノルタオプト株式会社 凝集量計測装置及び凝集量計測方法
WO2011010569A1 (ja) * 2009-07-24 2011-01-27 コニカミノルタオプト株式会社 マイクロチップ及び速度計測装置
WO2011065177A1 (ja) * 2009-11-26 2011-06-03 コニカミノルタオプト株式会社 血球軌跡表示装置
CN102639985A (zh) * 2009-11-26 2012-08-15 柯尼卡美能达先进多层薄膜株式会社 血球轨迹显示装置
US20120288926A1 (en) * 2009-11-26 2012-11-15 Konica Minolta Advanced Layers, Inc. Blood Cell Trajectory Displaying Device
JP5387689B2 (ja) * 2009-11-26 2014-01-15 コニカミノルタ株式会社 血球軌跡表示装置
JP2012098036A (ja) * 2010-10-29 2012-05-24 Sony Corp 試料流入装置、試料流入チップ及び試料流入方法
JP2017504007A (ja) * 2013-12-09 2017-02-02 テキサス テック ユニヴァーシティー システムTexas Tech University System 流体の高スループット分析のためのスマートフォンベースの多重化粘度計
CN112304877A (zh) * 2020-11-02 2021-02-02 南京润太医学检验实验室有限公司 一种用于血液流变检测的光电装置
CN112304877B (zh) * 2020-11-02 2022-11-04 南京润太医学检验实验室有限公司 一种用于血液流变检测的光电装置

Also Published As

Publication number Publication date
EP2219020A1 (en) 2010-08-18
EP2219020A4 (en) 2014-02-05
JP5146462B2 (ja) 2013-02-20
CN101874200B (zh) 2012-11-21
US20100260391A1 (en) 2010-10-14
JPWO2009069417A1 (ja) 2011-04-07
CN101874200A (zh) 2010-10-27

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