WO2009054243A1 - Aggregate of semiconductor nanoparticle phosphor, and biological substance labeling agent using the aggregate - Google Patents

Aggregate of semiconductor nanoparticle phosphor, and biological substance labeling agent using the aggregate Download PDF

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Publication number
WO2009054243A1
WO2009054243A1 PCT/JP2008/067915 JP2008067915W WO2009054243A1 WO 2009054243 A1 WO2009054243 A1 WO 2009054243A1 JP 2008067915 W JP2008067915 W JP 2008067915W WO 2009054243 A1 WO2009054243 A1 WO 2009054243A1
Authority
WO
WIPO (PCT)
Prior art keywords
aggregate
semiconductor nanoparticle
nanoparticle phosphor
biological substance
labeling agent
Prior art date
Application number
PCT/JP2008/067915
Other languages
French (fr)
Japanese (ja)
Inventor
Kazuyoshi Goan
Takuji Aimiya
Original Assignee
Konica Minolta Medical & Graphic, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Konica Minolta Medical & Graphic, Inc. filed Critical Konica Minolta Medical & Graphic, Inc.
Priority to JP2009538043A priority Critical patent/JPWO2009054243A1/en
Publication of WO2009054243A1 publication Critical patent/WO2009054243A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/02—Use of particular materials as binders, particle coatings or suspension media therefor
    • C09K11/025—Use of particular materials as binders, particle coatings or suspension media therefor non-luminescent particle coatings or suspension media
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/59—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing silicon

Abstract

This invention provides an aggregate of a semiconductor nanoparticle phosphor free from cytotoxicity, and a biological substance labeling agent using the aggregate. The aggregate of a semiconductor nanoparticle phosphor is an aggregate of a semiconductor nanoparticle phosphor subjected to physicochemical surface treatment. The aggregate of a semiconductor nanoparticle phosphor is characterized in that, in a cytotoxicity test by a neutral red method, each of the concentrations at which the absorbance of neutral red after the culture for one day and 10 days is reduced to 50% of the absorbance before the culture, i.e., IC50, is not less than 1000 µg/ml.
PCT/JP2008/067915 2007-10-25 2008-10-02 Aggregate of semiconductor nanoparticle phosphor, and biological substance labeling agent using the aggregate WO2009054243A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009538043A JPWO2009054243A1 (en) 2007-10-25 2008-10-02 Aggregates of semiconductor nanoparticle phosphors and biological material labeling agents using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-277383 2007-10-25
JP2007277383 2007-10-25

Publications (1)

Publication Number Publication Date
WO2009054243A1 true WO2009054243A1 (en) 2009-04-30

Family

ID=40579349

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/067915 WO2009054243A1 (en) 2007-10-25 2008-10-02 Aggregate of semiconductor nanoparticle phosphor, and biological substance labeling agent using the aggregate

Country Status (2)

Country Link
JP (1) JPWO2009054243A1 (en)
WO (1) WO2009054243A1 (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006070089A (en) * 2004-08-31 2006-03-16 Tokyo Denki Univ Environment-preservative nano silicon solution and nano silicon powder, and manufacturing method of the same
JP2006150344A (en) * 2004-09-29 2006-06-15 Toto Ltd Dispersion liquid containing photocatalytic titanium dioxide composite particulate
JP2006176859A (en) * 2004-12-24 2006-07-06 Canon Anelva Corp Method for producing silicon nano-crystal structure
JP2007063378A (en) * 2005-08-30 2007-03-15 Tokyo Denki Univ Nanosilicon-containing and white color-emitting silicon oxide film and method for producing the same
JP2007246329A (en) * 2006-03-15 2007-09-27 Tokyo Denki Univ Nano-silicon particle excellent in durability of light emission brightness and its producing method
JP2007269770A (en) * 2006-03-09 2007-10-18 Mitsubishi Chemicals Corp Functional magnetic super-nanoparticle and use thereof
JP2007284284A (en) * 2006-04-14 2007-11-01 National Institute Of Advanced Industrial & Technology Core/shell type particle and its manufacturing method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006315923A (en) * 2005-05-13 2006-11-24 Kenji Yamamoto Method for producing semiconductor nanoparticle

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006070089A (en) * 2004-08-31 2006-03-16 Tokyo Denki Univ Environment-preservative nano silicon solution and nano silicon powder, and manufacturing method of the same
JP2006150344A (en) * 2004-09-29 2006-06-15 Toto Ltd Dispersion liquid containing photocatalytic titanium dioxide composite particulate
JP2006176859A (en) * 2004-12-24 2006-07-06 Canon Anelva Corp Method for producing silicon nano-crystal structure
JP2007063378A (en) * 2005-08-30 2007-03-15 Tokyo Denki Univ Nanosilicon-containing and white color-emitting silicon oxide film and method for producing the same
JP2007269770A (en) * 2006-03-09 2007-10-18 Mitsubishi Chemicals Corp Functional magnetic super-nanoparticle and use thereof
JP2007246329A (en) * 2006-03-15 2007-09-27 Tokyo Denki Univ Nano-silicon particle excellent in durability of light emission brightness and its producing method
JP2007284284A (en) * 2006-04-14 2007-11-01 National Institute Of Advanced Industrial & Technology Core/shell type particle and its manufacturing method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HOSHINO A.: "Fluorescent labeling of cells and biomolecules with nanocrystal quantum dots", PROC. OF SPIE, vol. 5705, 2005, pages 263 - 271 *
SELVAN S.T.: "Robust, Non-Cytotoxic, Silica-Coated CdSe Quantum Dots with Efficient Photoluminescence", ADVANCED MATERIALS, vol. 17, 2005, pages 1620 - 1625 *

Also Published As

Publication number Publication date
JPWO2009054243A1 (en) 2011-03-03

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