WO2008152159A3 - Compuestos reguladores de la pigmentación - Google Patents

Compuestos reguladores de la pigmentación Download PDF

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Publication number
WO2008152159A3
WO2008152159A3 PCT/ES2008/000230 ES2008000230W WO2008152159A3 WO 2008152159 A3 WO2008152159 A3 WO 2008152159A3 ES 2008000230 W ES2008000230 W ES 2008000230W WO 2008152159 A3 WO2008152159 A3 WO 2008152159A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
dimethylchromane
meth0xy
pigmentation
acyloxy
Prior art date
Application number
PCT/ES2008/000230
Other languages
English (en)
French (fr)
Other versions
WO2008152159A2 (es
Inventor
Peypoch Angel Messeguer
Montiel Antonio Ferrer
Puche Juan Cebrian
Domenech Nuria Alminana
Serraima Cristina Carreno
Original Assignee
Lipotec Sa
Peypoch Angel Messeguer
Montiel Antonio Ferrer
Puche Juan Cebrian
Domenech Nuria Alminana
Serraima Cristina Carreno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipotec Sa, Peypoch Angel Messeguer, Montiel Antonio Ferrer, Puche Juan Cebrian, Domenech Nuria Alminana, Serraima Cristina Carreno filed Critical Lipotec Sa
Priority to JP2010511666A priority Critical patent/JP5455897B2/ja
Priority to US14/175,312 priority patent/USRE46228E1/en
Priority to KR1020107000911A priority patent/KR101463286B1/ko
Priority to CN2008800203653A priority patent/CN101730689B/zh
Priority to EP08761477.2A priority patent/EP2159223B1/en
Priority to US12/440,707 priority patent/US8110207B2/en
Priority to ES08761477.2T priority patent/ES2468368T3/es
Publication of WO2008152159A2 publication Critical patent/WO2008152159A2/es
Publication of WO2008152159A3 publication Critical patent/WO2008152159A3/es
Priority to ZA2009/08596A priority patent/ZA200908596B/en
Priority to HK10106777.4A priority patent/HK1140476A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00—Manicure or pedicure preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists

Abstract

La presente invención hace referencia a compuestos de fórmula general (I) en donde X se selecciona del grupo formado por O o S y R es un grupo alifático con de 2 a 23 átomos de carbono (C2 a C23) lineal o ramificado, saturado o insaturado, o un grupo cíclico, y que pueden contener sustituyentes seleccionados del grupo formado por hidroxi, alcoxi, amino, carboxilo, ciano, nitro, alquilsulfonilo o átomos de halógeno, un método de obtención, composiciones cosméticas o farmacéuticas que los contienen y su uso para el tratamiento, cuidado y/o limpieza de Ia piel, cabello y/o uñas, preferentemente aquellas condiciones, desórdenes o patologías de Ia piel, cabello y/o uñas que requieran Ia regulación de Ia melanogénesis.
PCT/ES2008/000230 2007-06-15 2008-04-11 Compuestos reguladores de la pigmentación WO2008152159A2 (es)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP2010511666A JP5455897B2 (ja) 2007-06-15 2008-04-11 色素沈着の調節化合物
US14/175,312 USRE46228E1 (en) 2007-06-15 2008-04-11 Pigmentation-regulating compounds
KR1020107000911A KR101463286B1 (ko) 2007-06-15 2008-04-11 색소침착 조절 화합물
CN2008800203653A CN101730689B (zh) 2007-06-15 2008-04-11 色素调节化合物
EP08761477.2A EP2159223B1 (en) 2007-06-15 2008-04-11 6 -acyloxy- 7-meth0xy- 2, 2 -dimethylchromane compounds and their use as pigmentation-regulators
US12/440,707 US8110207B2 (en) 2007-06-15 2008-04-11 Pigmentation-regulating compounds
ES08761477.2T ES2468368T3 (es) 2007-06-15 2008-04-11 Compuestos 7-metoxi-2,2-dimetilcromanos 6-sustituidos y su uso como reguladores de la pigmentaci�n
ZA2009/08596A ZA200908596B (en) 2007-06-15 2009-12-03 Regulatory compounds for pigmentation
HK10106777.4A HK1140476A1 (en) 2007-06-15 2010-07-13 Regulatory compounds for pigmentation

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ESP200701663 2007-06-15
ES200701663A ES2310142B1 (es) 2007-06-15 2007-06-15 Compuestos reguladores de la pigmentacion.
US3708508P 2008-03-17 2008-03-17
US61/037,085 2008-03-17

Publications (2)

Publication Number Publication Date
WO2008152159A2 WO2008152159A2 (es) 2008-12-18
WO2008152159A3 true WO2008152159A3 (es) 2009-01-29

Family

ID=40084602

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2008/000230 WO2008152159A2 (es) 2007-06-15 2008-04-11 Compuestos reguladores de la pigmentación

Country Status (12)

Country Link
US (2) US8110207B2 (es)
EP (1) EP2159223B1 (es)
JP (1) JP5455897B2 (es)
KR (1) KR101463286B1 (es)
CN (1) CN101730689B (es)
CL (1) CL2008001278A1 (es)
ES (2) ES2310142B1 (es)
HK (1) HK1140476A1 (es)
MY (1) MY148437A (es)
TW (1) TWI407976B (es)
WO (1) WO2008152159A2 (es)
ZA (1) ZA200908596B (es)

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EP2316416B1 (de) 2009-10-28 2015-12-23 PM-International AG Hautaufhellende kosmetische Zusammensetzung
KR101688815B1 (ko) * 2010-08-13 2016-12-23 (주)아모레퍼시픽 프로판노이드 유도체를 함유하는 백모 방지용 및 백반증 치료용 조성물
JP6005397B2 (ja) * 2012-05-18 2016-10-12 株式会社コーセー 皮膚外用剤
CN102697702B (zh) * 2012-06-08 2013-04-17 钟春燕 一种美白保湿修复体膜及制备方法
CN102670480B (zh) * 2012-06-08 2013-05-22 钟春燕 一种控油保湿修复体膜及制备方法
DE102012222970A1 (de) * 2012-12-12 2014-06-12 Henkel Ag & Co. Kgaa Wirkstoffkombination zur Hautaufhellung I
EP2789369B1 (en) * 2013-04-14 2018-06-06 Symrise AG A composition for lightening skin and hair
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
DE102014211185A1 (de) * 2014-06-11 2015-12-17 Henkel Ag & Co. Kgaa Kosmetische Zusammensetzungen zur Hautaufhellung
WO2016014529A1 (en) * 2014-07-21 2016-01-28 Wisys Technology Foundation, Inc. Skin lightening compounds
CA2962932A1 (en) * 2014-09-29 2016-04-07 Elc Management Llc Actives for stimulating differentiation of keratinocytes to lighten hyperpigmented skin
MX2017005597A (es) * 2014-10-31 2017-06-23 Lubrizol Advanced Mat Inc Pelicula de poliuretano termoplastico para la liberacion de agentes activos a superficies de piel.
JP6594661B2 (ja) * 2015-05-25 2019-10-23 月桂冠株式会社 新規染色剤原料の製造方法
FR3036617B1 (fr) * 2015-05-27 2018-08-31 L'oreal Derives (1-phenyl-2-phenyl) ethylene polyhydroxyles a titre d'agent anti-age et photoprotecteur
US20180311358A1 (en) 2015-11-05 2018-11-01 Lubrizol Advanced Materials, Inc. Thermoformable dual network hydrogel compositions
US10493020B2 (en) 2016-04-14 2019-12-03 The Procter & Gamble Company Method of improving the appearance of periorbital dyschromia
JP7171355B2 (ja) * 2018-10-05 2022-11-15 株式会社ナリス化粧品 メラニン分解促進剤
CN109971269B (zh) * 2019-04-08 2020-11-06 沈阳顺风新材料有限公司 一种环保疏水涂料
CN110123819B (zh) * 2019-06-03 2022-03-15 南阳南石医院 一种用于治疗疤痕的药物和装置
EP3785696A1 (en) * 2019-08-28 2021-03-03 B.R.A.I.N. Biotechnology Research And Information Network AG Cosmetic use of aromatic formamidine derivatives
CN115087427A (zh) * 2019-12-10 2022-09-20 玫琳凯有限公司 用于处理皮肤的草本化妆品组合物
WO2021253053A1 (en) 2020-06-12 2021-12-16 Mary Kay Inc. Topical compositions and methods
CN114073654A (zh) * 2020-08-21 2022-02-22 大江生医股份有限公司 露莓汁液用于制备调理肌肤的组合物的用途
CN116948961B (zh) * 2023-09-20 2023-11-24 内蒙古奕宏医学研究有限公司 一种白细胞提取物、抗皱紧致面霜及其制备方法

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Also Published As

Publication number Publication date
KR101463286B1 (ko) 2014-11-27
EP2159223A2 (en) 2010-03-03
ES2310142B1 (es) 2009-12-04
JP2010529978A (ja) 2010-09-02
CN101730689A (zh) 2010-06-09
JP5455897B2 (ja) 2014-03-26
CL2008001278A1 (es) 2009-04-17
EP2159223B1 (en) 2014-03-12
HK1140476A1 (en) 2010-10-15
ES2468368T3 (es) 2014-06-16
CN101730689B (zh) 2013-08-14
WO2008152159A2 (es) 2008-12-18
ES2310142A1 (es) 2008-12-16
TW200904481A (en) 2009-02-01
US8110207B2 (en) 2012-02-07
TWI407976B (zh) 2013-09-11
ZA200908596B (en) 2011-03-30
MY148437A (en) 2013-04-30
USRE46228E1 (en) 2016-12-06
US20100247587A1 (en) 2010-09-30
KR20100040857A (ko) 2010-04-21

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