WO2008124994A1 - A green environmental protection feed additive for fowls and domestic animals and its preparation method - Google Patents
A green environmental protection feed additive for fowls and domestic animals and its preparation method Download PDFInfo
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- WO2008124994A1 WO2008124994A1 PCT/CN2008/000344 CN2008000344W WO2008124994A1 WO 2008124994 A1 WO2008124994 A1 WO 2008124994A1 CN 2008000344 W CN2008000344 W CN 2008000344W WO 2008124994 A1 WO2008124994 A1 WO 2008124994A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/32—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from hydrolysates of wood or straw
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
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- the inventors have conducted research on the development of natural biologically active substances for many years and found that as a feed additive, it is subjected to storage, transportation, and secondary processing from production to application (animal feeding into the body) (mixing with other feed ingredients)
- the price term, in this process may experience high temperature and harsh environment such as granulation, puffing, etc.)
- volatile components such as essential oils
- the green livestock feed additive of the invention comprises non-effective (or non-functional) component water, alcohol insoluble matter (hazelnut) and effective component or functional component water, alcohol soluble substance or extract . It is characterized in that: water, alcohol insoluble matter is mainly plant cellulose, hemicellulose, lignin; water and alcohol extract mainly include terpenoids, polysaccharides, anethole, chlorogenic acid, propene, quercetin, a compound such as emodin, emodin, an indole, an iridoid, or a nucleoside, furan, sterol, sitosterol, borneol, alkaloid, protein, biological polypeptide, amino acid, Examples include flavonoids such as flavonoids, geniposide, and geniposide, mannitol, phospholipids, p-propenyl phenol isopentenes, and trace elements.
- the ratio of the compound to the total amount of water and alcohol extract, by weight, the polysaccharide is in the range of 15-45%, the steroid is in the range of 12-41%, the fennel is in the range of 1-2%, chlorogenic acid In the range of 1.5 to 5%, the olefin is in the range of 0.1 to -3 ° /. ⁇ , quercetin, emodin, emodin methyl ether, conjugated quinones in the range of 0. 5- -2%, iridoids quinone compounds 0. 5- -2% range.
- the extract contains not less than 1% chlorogenic acid, and its main basic chemical structure is:
- the formula selection principle of the green and environmentally-friendly livestock feed additive of the invention can be obtained by compounding compound or natural material (including animal, plant and microbial materials). It can be prepared by mixing plant cellulose, hemicellulose, lignin, physiologically active ganoderma lucidum or its culture products. It is also possible to use one or more kinds of plants or Chinese herbal medicines containing triterpenoids and polysaccharides. Or fungi, using existing The technology is prepared by preparation; it can also be prepared by using existing biotechnology fermentation engineering. It is an excellent product obtained by processing Chinese herbal medicine Ganoderma lucidum or its culture, Cordyceps militaris or its culture.
- Ganoderma lucidum polysaccharide is the main component of Ganoderma lucidum to strengthen the body, nourish and strengthen, and prolong life. No toxic side effects, can be used for medicine. Clinical trials have also confirmed that Ganoderma lucidum polysaccharides can be used as an effective adjuvant therapy for tumor chemotherapy and radiation therapy.
- the chemical constituents of Ganoderma lucidum or its culture are: triterpenoids, polysaccharides, nucleosides, alcohols, alkaloids, furan derivatives, amino acid polypeptides, inorganic elements, fatty acids, and the like.
- Eucommia ulmoides contains gutta percha, polysaccharide, flavonoids, rosinol diglucoside, arachidin, genipin, phenylpropanoids, chlorogenic acid, musk, coumarin, quercetin, hawthorn Secondary active metabolites such as alcohols, their iridoids and lignans, sucrose disaccharide (SGD), genipin (GA) compounds, etc., containing 17 amino acids. With more than 20 kinds of trace elements, the nutrition is very rich. Among them, chlorogenic acid (CH) is one of the main active ingredients of the valuable Chinese herbal medicine Eucommia ulmoides Oliv. It has strong inhibition and killing effect on various pathogenic bacteria and viruses. It is an antibacterial and detoxification of Chinese patent medicines. 3. The main active ingredient of analgesic and anti - inflammatory and choleretic.
- the use amount of the green and environmentally-friendly livestock and poultry feed additive of the present invention in the feed is generally selected in the range of 0.1 to 5% by weight, and the addition is only the cost increase.
- Group B formula 30-50 parts of bone powder, 50-80 parts of animal and plant materials containing protein (such as fish meal, soy flour, biological protein, etc.), calcium phosphate mineral or shell powder 0-20 parts , 350-950 parts of carbohydrate plant material (such as starchy rice flour, flour, corn 'powder, wheat bran, potato, etc.).
- protein such as fish meal, soy flour, biological protein, etc.
- calcium phosphate mineral or shell powder 0-20 parts
- carbohydrate plant material such as starchy rice flour, flour, corn 'powder, wheat bran, potato, etc.
- control group was under the same conditions as the test group without additives.
- Test effect :
- Feeding the velvet period deer Take two groups, each group of 60 bred deer, a statistical comparison of the antler production period, the test group is 10% higher than the control group.
- Example 1-13 The additives of Examples 1-13 were used for the cow feed test, respectively:
- the control group was under the same conditions as the test group without additives.
- the Cordyceps and its culture are mainly used as a medium for the royal jelly.
- the Cordyceps species are placed in a medium, placed in a glass container, and cultured at a certain temperature, R degree, and illumination.
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Abstract
A green environmental protection feed additive for fowls and domestic animals and its preparation method, its main components are plant cellulose, hemicellulose, lignin, triterpene with physiological activity, and polysaccharides materials. Furthermore, it contains a little amount of biological active compounds such as nucleotide, furan, sterol, alkaloid, protein and amino acids, anise camphor, trace elements etc.
Description
绿色环保畜禽伺料添加剂及其制备方法 技术领域 Green environmental livestock and poultry feed additive and preparation method thereof
本发明属于一种绿色环保畜禽饲料添加剂。 The invention belongs to a green environmental protection livestock and poultry feed additive.
背景技术 Background technique
随着现代词养业向规模化、 集约化发展, 大量抗菌素 (含微生物发酵 和化工合成来源的具抗微生物作用之物质, 下同) 被作为饲料添加剂, 庙 于防治畜禽疾病, 促进动物生长发育。 目前, 全球用于饲料添加剂的抗菌 素品种约有 60多种, 我国批准使用的有约 20种左右。 抗菌素在饲料中的 应用, 为养殖业的数量型快速增长, 满足人类对动物性食品的需求作出了 巨大贡献。 饲料中长期使用抗菌素, 其负作用也越来越突出: (1 ) 耐药性- 饲料中长期低剂量添加抗菌素, 不仅可使动物细菌产生耐药性, 而且这种 耐药性可通过耐药因子(R因子)传递给人体内的病菌, 导致对人类健康的 潜在威胁; (2 ) 长期使用抗菌素造成畜禽机体的免疫力下降; (3 ) 长期使 用抗菌素可引起畜禽的内源性感染或二重感染; (4) 长期使用抗菌素会在 畜产品或环境中形成残留, 这些残留的抗菌素通过食物链蓄积于人体, 导 致人体产生大量耐药菌株, 失去对某些疾病的抵抗力, 还可引发过敏反应, 产生致畸、 致癌、 致突变作用, 对人类健康构成严重威胁。 基于对抗菌素 负作用的认识, 世界各国相继禁止、 限制抗菌素在饲料中的应用, 并十分 重视抗菌素替代物的研制开发。 目前正研究开发并推广使用的抗菌素替代 物有词用微生物制剂、 低聚糖、 中草药饲料添加剂、 天然生物活性物质等。 饲料微生物在实际应用中效果不稳定, 受多种因素影响: 动物种类、 动物 生物状态、 饲料类型及成份、 词料加工工艺、 菌株组成及其定植能力、 使 用方式及剂量、 水分、 温度、 PH值、 其它饲料添加剂成份的干扰和菌剂的 保存时间等; 中草药饲料添加剂加量大, 药效慢, 适口性差, 严重影响采 食量和消化率, 原材料因受不同季节、 产地的限制, 有效成份相差很大, 难以进行准确的药效评定和有效的质量控制, 产品稳定性差, 效果经不起 重复验证和严格的检验, 因而未能在生产中大面积推广应用; 低聚糖虽克 服了词用微生物制剂保存和在肠道定植的缺陷, 但体外研究条件和体内胃 肠道环境的巨大差异, 使理论模型难以在实践应用中得到有效的表达、 体
现; 天然生物活性物质的研究开发是建立在现代科学解析型思维方法的基 础上, 从纯天然目标植物中提取目标化合物 (功效成份), 并建立气液相色 谱等现代化的分析检测方法, 监控产品中功效成份含量, 确保了产品的可 控性和稳定性, 保证了产品质量。 饲用天然生物活性物质的研究在国内外 均刚刚起步, 但必将是抗菌素替代物的发展方向。 中国专利 96105034. 9公 开了一种从茶油饼中提取三萜类皂素作为饲料添加剂应用的方法。 荷兰某 公司从植物牛至中提取挥发性精油类成份, 制造饲料添加剂, 并以 "诺必 达"品名获准在中国销售。 发明人对天然生物活性物质的饲用开发进行了 多年的研究, 发现作为饲料添加剂, 由于在生产至应用 (动物摄食进入体 内) 要经历贮藏、 运输、 二次加工 (与其它饲料成份混合生产全价词料, 在此环节可能会经历制粒、 膨化等高温恶劣环境) 诸多环节, 时间长, 因 此不宜使用挥发性的成份, 如精油等, 因为有效成份的非可控模型损失, 会使产品中的功效成份不恒定, 影响效果的均一表达。 With the development of modern word industry to large-scale and intensive, a large number of antibiotics (substances with microbial fermentation and chemical synthesis derived from antimicrobial effects, the same below) are used as feed additives to prevent animal diseases and promote animal growth. development. At present, there are about 60 kinds of antibiotics for feed additives in the world, and about 20 kinds are approved for use in China. The application of antibiotics in feed has greatly contributed to the rapid growth of the quantity of the aquaculture industry and the satisfaction of human needs for animal foods. The long-term use of antibiotics in feeds has an increasingly negative effect: (1) Drug resistance - the long-term low-dose addition of antibiotics to feeds not only can cause bacterial resistance in animal bacteria, but also through drug resistance. Factor (R factor) is transmitted to the human body, causing potential threat to human health; (2) long-term use of antibiotics causes decreased immunity of livestock and poultry; (3) long-term use of antibiotics can cause endogenous infection of livestock and poultry Or double infection; (4) long-term use of antibiotics will form residues in animal products or the environment. These residual antibiotics accumulate in the human body through the food chain, resulting in a large number of drug-resistant strains in the human body, losing resistance to certain diseases, It triggers allergic reactions, produces teratogenic, carcinogenic, mutagenic effects and poses a serious threat to human health. Based on the understanding of the negative effects of antibiotics, countries around the world have banned and restricted the application of antibiotics in feed, and attached great importance to the research and development of antibiotic substitutes. At present, the antibiotic substitutes that are being researched and developed are used as microbial preparations, oligosaccharides, Chinese herbal medicine feed additives, natural biological active substances, and the like. Feed microbes are unstable in practical applications and are affected by many factors: animal species, animal biological status, feed type and composition, word processing technology, strain composition and colonization ability, usage and dosage, moisture, temperature, PH Value, interference of other feed additive components and preservation time of microbial agents; Chinese herbal medicine feed additives are large in dosage, slow in efficacy, poor in palatability, seriously affecting feed intake and digestibility, and raw materials are limited by different seasons and places of origin. The composition varies greatly, it is difficult to carry out accurate efficacy evaluation and effective quality control, the product stability is poor, the effect can not withstand repeated verification and rigorous testing, so it can not be widely applied in production; oligosaccharides have overcome The word is preserved by microbial preparations and defects in colonization in the intestine, but the in vitro study conditions and the huge differences in the gastrointestinal environment of the body make it difficult for the theoretical model to be effectively expressed and applied in practical applications. Nowadays; the research and development of natural biological active substances is based on the modern scientific analytical thinking method, extracting target compounds (functional components) from pure natural target plants, and establishing modern analytical detection methods such as gas liquid chromatography, monitoring The content of functional ingredients in the product ensures the controllability and stability of the product and ensures the quality of the product. The research on natural bioactive substances for feeding has just started at home and abroad, but it will definitely be the development direction of antibiotic alternatives. Chinese Patent No. 96105034. 9 discloses a method for extracting triterpenoid saponin from tea cake as a feed additive. A Dutch company extracts volatile essential oils from plant oregano, manufactures feed additives, and is allowed to sell in China under the name of “Nobita”. The inventors have conducted research on the development of natural biologically active substances for many years and found that as a feed additive, it is subjected to storage, transportation, and secondary processing from production to application (animal feeding into the body) (mixing with other feed ingredients) The price term, in this process may experience high temperature and harsh environment such as granulation, puffing, etc.) Many links, long time, so it is not appropriate to use volatile components, such as essential oils, because the loss of non-controllable model of active ingredients will make the product The efficacy component is not constant, affecting the uniform expression of the effect.
发明内容 Summary of the invention
本发明的目的在于: 提出一种绿色环保畜禽饲料添加剂。 The object of the present invention is to propose a green and environmentally friendly livestock and poultry feed additive.
本发明的另一目的在于: 提出一种绿色环保畜禽饲料添加剂制备配方。 本发明的再一目的在于: 提出一种绿色环保畜禽词料添加剂制备方法。 本发明还有一目的在于: 提出一种绿色环保饲料添加剂的用途。 Another object of the present invention is to provide a green environmentally friendly livestock and poultry feed additive preparation formula. A further object of the present invention is to provide a method for preparing a green environmentally-friendly livestock word additive. Still another object of the present invention is to provide a use of a green environmentally friendly feed additive.
本发明的绿色环保的畜禽饲料添加剂, 其包括非有效 (或无功能)的成 分水、 醇不溶物 (碴子) 和有效的成分或功能成分水、 醇可溶物或称提取 物两部分。 其特征在于: 水、 醇不溶物主要为植物纤维素、 半纤维素、 木 素; 水、 醇提取物主要包括萜类、 多糖类、 茴香脑、 绿原酸、 派烯、 槲皮 素、 大黄素、 大黄素甲醚、 结合蒽醌类、 环烯醚萜甙类等化合物, 此外还 含有核苷、 呋喃、 甾醇、 谷甾醇 谷甾醇、 龙脑、 生物碱、 蛋白质、 生 物多肽、 氨基酸、 黄酮、 京尼平苷、 京尼平苷酸等环烯醚类、 甘露醇、 磷 脂、对丙烯基苯酚异戊烯醚、微量元素等。其醇提取物含量重量在 0. 3—27% 范围, 用水在 ΡΗ 7- 9的条件下提取, 其水提取物含量重量在 0. 5 --- 35%范 围。其醇提取物含量重量优选在 1. 3—- 15%范围, 其水提取物含量重量优选 在 1. 5- -21%范围。其萜类主要为五环三萜、 四环三萜化合物, 其五环三萜、 四环三萜中主要是以灵芝三萜和人参所含皂苷。 其水、 醇提取物中的主要
化合物,各占水、醇提取物总量的比例, 以重量计, 多糖类在 15—45%范围, 萜类在 12- -41%范围, 茴香脑在 1一 2%范围, 绿原酸在 1. 5— 5%范围, 派烯 在 0. 1- -3°/。范围, 槲皮素、 大黄素、 大黄素甲醚, 结合蒽醌类在 0. 5- -2%范 围,环烯醚萜甙类化合物 0. 5- -2%范围。 The green livestock feed additive of the invention comprises non-effective (or non-functional) component water, alcohol insoluble matter (hazelnut) and effective component or functional component water, alcohol soluble substance or extract . It is characterized in that: water, alcohol insoluble matter is mainly plant cellulose, hemicellulose, lignin; water and alcohol extract mainly include terpenoids, polysaccharides, anethole, chlorogenic acid, propene, quercetin, a compound such as emodin, emodin, an indole, an iridoid, or a nucleoside, furan, sterol, sitosterol, borneol, alkaloid, protein, biological polypeptide, amino acid, Examples include flavonoids such as flavonoids, geniposide, and geniposide, mannitol, phospholipids, p-propenyl phenol isopentenes, and trace elements. 5%范围内。 The water extract content of the weight of the water extract in the range of 0. 3 --- 35% range. 5%的范围内。 The weight of the water extract is preferably in the range of 1. 5 - 15%. Its anthraquinones are mainly pentacyclic triterpenoids and tetracyclic triterpenoids. Among them, the five-ring triterpenoids and tetracyclic triterpenes are mainly saponins containing Ganoderma lucidum and ginseng. Mainly in water and alcohol extracts The ratio of the compound to the total amount of water and alcohol extract, by weight, the polysaccharide is in the range of 15-45%, the steroid is in the range of 12-41%, the fennel is in the range of 1-2%, chlorogenic acid In the range of 1.5 to 5%, the olefin is in the range of 0.1 to -3 ° /.范围范围内, quercetin, emodin, emodin methyl ether, conjugated quinones in the range of 0. 5- -2%, iridoids quinone compounds 0. 5- -2% range.
由于本发明的绿色环保的畜禽饲料添加剂, 是采用天然材料、 绿色环 保的物质 (包括动、 植物、 矿物、 生物产物等) 作原料, 其水、 醇不溶物 (碴子)量一般可在 35- 95%范围; 水、 醇提取物一般可在 0. 8- 62%范围,其 优选在 2. 8- 36%范围;水、醇提取物含量越高,其原料价格越高,成本越高; 挥发损失物一般可在 3- 4. 2%范围。 水、 醇不溶物 (碴子) 的主要成分是纤 维素、 半纤维素、 木素。 其植物类纤维素、 半纤维素、 木素的比例,纤维素 占有量一般不少于 30%, 多数在 30- 50%之间; 半纤维素占有量一般不少于 10%, 多数在 10- 25%之间; 木素占有量一般不少于 8%, 多数在 8- 35%之间。 这些高分子化合物占有多少量的变化, 对本发明并不重要, 其植物长龄差 异和不同种类, 其中纤维素、 半纤维素、 木素的比例也有很大差别, 是众 所周知的常识。 在本发明中不用作控制指标, 也不是必须控制指标, 也不 需要特别或人为设计其各量及其比例, 只需采用含有本发明的绿色环保的 畜禽词料添加剂有效化合物的天然材料物质 (动、 植物、 矿物) 作原料材 料,均可实现、 制备、 获得本发明的绿色环保的畜禽饲料添加剂产品。 一般 地说, 其是由所取材自然形成一定比例, 其各量及其比例变化均不影响本 发明的绿色环保畜禽饲料添加剂的效果。 以配制方法制备, 有意加入这些 物质仅是降低成本或作提取物的载体而已; 本行业一般技术人员不须知到 其碴子中的成分比例, 均可实现制备获得本发明的绿色环保的畜禽饲料添 加剂产品。 Since the green and livestock feed additive of the present invention uses natural materials and green materials (including animals, plants, minerals, biological products, etc.) as raw materials, the amount of water and alcohol insoluble matter (tweezers) can generally be 35- 95% range; water, alcohol extract can generally range from 0. 8- 62%, which is preferably in the range of 2. 8- 36%; the higher the water and alcohol extract content, the higher the raw material price, the more the cost High; volatile loss can generally be in the range of 3-4. 2%. The main components of water and alcohol insolubles (hazelnuts) are cellulose, hemicellulose, and lignin. The proportion of cellulose, hemicellulose and lignin in plants is generally not less than 30%, most of them are between 30% and 50%; the hemicellulose content is generally not less than 10%, most of which is 10 - between 25%; lignin occupancy is generally not less than 8%, and most are between 8 and 35%. The amount of these high molecular weight compounds is not critical to the present invention. Plant length differences and different types, among which cellulose, hemicellulose, and lignin ratios are also greatly different, are well-known common sense. In the present invention, it is not used as a control index, nor is it necessary to control the index, nor is it necessary to specially design its various amounts and proportions thereof, and it is only necessary to use a natural material substance containing the green and environmentally-friendly animal word additive effective compound of the present invention. (Activities, plants, minerals) As raw material materials, the green and environmentally-friendly livestock and poultry feed additive products of the present invention can be realized, prepared and obtained. Generally speaking, it is naturally formed by a certain proportion of the materials taken, and the respective amounts and their proportion changes do not affect the effect of the green environmentally-friendly livestock feed additive of the present invention. Prepared by the preparation method, intentional addition of these substances is only a cost reduction or a carrier for the extract; the general skilled person in the industry does not need to know the proportion of the components in the scorpion, can achieve the preparation of the green animal husbandry of the present invention Feed additive products.
本发明的绿色环保畜禽词料添加剂, 其主要功能成分为萜类、 茴香脑、 绿原酸、 派烯、 槲皮素、 大黄素、 大黄素甲醚; 结合蒽醌类、 环烯醚萜甙 类等化合物, 其特征在于: The green functional livestock and poultry word additive of the invention has the main functional components: anthraquinone, anethole, chlorogenic acid, propene, quercetin, emodin, emodin methyl ether; combined anthraquinone, iridoid a compound such as a quinone, which is characterized by:
A、 其萜类主要为五环三萜、 四环三萜化合物, 其中有 60%以上的灵芝 三萜, 其灵芝三萜中有不少于 10%的三萜为下述基本结构;
其 Rl, R2, R3可分别是 1-- 4:碳的烯基、 烷基、 羟基、 羧基、 酮基、 酸基、醚基等之一的功能团。其中 C8-C9, C11-C12, C16-17 , C20-22 , C23-24 为双键结构的高活性三萜, 其含量以重量计, 占总萜的 1-6%左右。 A. The anthraquinones are mainly pentacyclic triterpenoids, tetracyclic triterpenoids, of which more than 60% of Ganoderma lucidum triterpenoids, and not less than 10% of the Ganoderma lucidum triterpenoids are the following basic structures; R1, R2, and R3 may each independently be a functional group of one of 4- to 4-carbon: an alkenyl group, an alkyl group, a hydroxyl group, a carboxyl group, a ketone group, an acid group, an ether group, and the like. Among them, C8-C9, C11-C12, C16-17, C20-22 and C23-24 are high-activity triterpenes with double bond structure, and their contents are about 1-6% of total ruthenium by weight.
B、 其中人参皂苷含量占萜总量的 10%以上, 即萜类中含有不少于 10% 的人参皂苷。 B. The ginseng saponin content accounts for more than 10% of the total strontium, that is, the quinone contains not less than 10% ginsenoside.
C、 其提取物中含有不少于 1%的绿原酸, 其主要基本化学结构为: C. The extract contains not less than 1% chlorogenic acid, and its main basic chemical structure is:
D、 茴香脑中, 其反式茴香脑不少于 75%。 D. In the fennel brain, the trans-fennel brain is not less than 75%.
E、 派烯中, 其 cc 派烯不少于 75%。 E, in the olefin, its cc is not less than 75%.
F、 大黄素、 大黄素甲醚、 结合蒽醌类成分主要由大黄素- 8-0- β -D -葡
萄糖苷 (PMEG)、 大黄酚 -8-0- β -D-葡萄糖苷、 大黄素甲醚- 8-0- β -D-葡萄 糖苷组成。 F, emodin, emodin methyl ether, combined terpenoids are mainly composed of emodin - 8-0- β -D - Portuguese Glucosamine (PMEG), chrysophanol-8-0-β-D-glucoside, emodin methyl ether 8-0-β-D-glucoside composition.
G、 二苯乙烯苷类成分主要为 2,3, 5,4' -四羟基二苯乙烯 -2-0- - D - 葡萄糖苷 (ST), 含量占 90%以上。 G, the stilbene glycoside component is mainly 2,3,5,4'-tetrahydroxystilbene-2-0--D-glucoside (ST), and the content accounts for more than 90%.
H、 环烯醚萜甙类化合物, 其主要活性成分为梓醇 (catalpol )、 甘露 醇、 β -谷甾醇。 H. Iridoids, the main active ingredients of which are catalpol, mannitol and β-sitosterol.
I、 多糖类主要包含葡聚糖、 杂多糖和肽多糖的多糖, 其分子量在 3000 — 500000之间。 I. Polysaccharides mainly contain polysaccharides of dextran, heteropolysaccharides and peptide polysaccharides, and their molecular weights are between 3,000 and 500,000.
本发明的绿色环保畜禽词料添加剂, 其醇提取物含量以重量计, 在 0. 3- -27%范围, 其醇提取物优化含量以重量计, 在 1. 3— 15%范围。 其提取 物主要成份为萜类、 氯原酸 (chlorogenic acid, CHA)、 茴香脑化合物。 其 萜类根据其所含功能团和不同的侧链可为三萜醇、 三萜醛、 三萜酸等, 且 具有生理活性。在三萜酸的结构中,环上的双键大多位于 C8- - C9位,在 C11 位和 C23位大部分有羰基, 而且在 C3、 C7、 C15位也多被羟基或羰基所取 代。 在三萜醇、 醛和过氧化物的结构中环上大多存在两个不饱和双键, 其 位置在 C7- - C8, C9— C11位, C11位和 C23位不存在羰基。 The environmentally friendly livestock and poultry word additive of the present invention has an alcohol extract content in the range of 0.3 to -27% by weight, and the alcohol extract is optimized in an amount of from 1.3 to 15% by weight. The main components of the extract are terpenoids, chlorogenic acid (CH), and fennel compounds. The quinones may be triterpene alcohol, triterpenal aldehyde, triterpenic acid or the like according to functional groups and different side chains thereof, and have physiological activity. In the structure of triterpenic acid, most of the double bonds on the ring are located at the C8--C9 position, and most of them have a carbonyl group at the C11 and C23 positions, and are also substituted by a hydroxyl group or a carbonyl group at the C3, C7, and C15 positions. In the structure of triterpene alcohol, aldehyde and peroxide, there are mostly two unsaturated double bonds in the ring, which are located at C7--C8, C9-C11, and no carbonyl group at C11 and C23.
本发明的绿色环保畜禽饲料添加剂, 用水在 PH 7- -9 的条件下提取, 其水提取物含量以重量计, 在 0. 5—35%范围, 其水提取物优化含量以重量 计, 在 1. 5- -21%范围。 其水提取物主要成份是包含葡聚糖、 杂多唐和肽多 糖等的多糖; 其分子量在 3000— 500000之间。 水提取物经净化处理后, 真 空干燥可获得白色结晶或粉末。 主要是 BN3和 GL两大类, 前者包括 BN3A、 BN3B和 BN3C, 后者包括 GLA、 GLB和 GLC。 这两类多糖在理化性质上均有一 定差异。 性质易溶于水。 有代表性的是分子量 40000的 BN3C多糖和分子量 12000GLA多糖, 其化学结构为肽多糖, 糖链又以 β (1-6) β (1一 3)连接, 所含 β (1-6)式链愈多, 多糖的活性愈大, 而含有 β (1-4)式链接或含乙酰 基者则作用较差。 此外多糖的活性必须为螺旋型立体结构。 The environmentally-friendly livestock and poultry feed additive of the present invention is extracted with water at a pH of from 7 to -9, and the water extract content is in the range of 0.5 to 35% by weight, and the optimum content of the water extract is by weight. In the range of 1. 5--21%. The main component of the water extract is a polysaccharide comprising dextran, heteropolyphenol and peptide polysaccharide; its molecular weight is between 3,000 and 500,000. After the water extract is purified, it is vacuum dried to obtain white crystals or powder. Mainly BN3 and GL are two categories, the former including BN3A, BN3B and BN3C, the latter including GLA, GLB and GLC. These two types of polysaccharides have different physical and chemical properties. The property is easily soluble in water. Representatively, the BN3C polysaccharide with a molecular weight of 40,000 and the polysaccharide of 12000GLA have a chemical structure of a peptide polysaccharide, and the sugar chain is further linked by β (1-6) β (1 - 3), and the β (1-6) chain is contained. The more the polysaccharide is active, the less the beta (1-4)-linked or the acetyl-containing group is. In addition, the activity of the polysaccharide must be a helical stereostructure.
本发明的绿色环保畜禽饲料添加剂的配方选择原则, 可采用化合物或 天然材料 (包括动、 植物、 微生物材料) 组配获得。 可选用植物纤维素、 半纤维素、 木素、 有生理活性的灵芝或其培养物产品混合方法来制得; 也 可选用含有三萜类、 多糖类的一种或多种植物或中药材或菌类, 采用现有
技术进行配制而获得; 还可采用现有的生物技术发酵工程来制备。 以中药 材灵芝或其培养物、 冬虫草或其培养物等为原料进行加工可获得极佳的产 品。 灵芝或其培养物是为数不多的同时含具有生理活性的三萜、 多糖两大 类化合物材料; 虫草或其培养物富含多糖。 灵芝三萜、 多糖和虫草多糖以 及所含的诸多的核苷、 呋喃、 醇、 生物碱、 蛋白质、 氨基酸等有生理活 性化合物和微量元素, 其卓著功效已被现代科学证实, 因此灵芝或其培养 物、 冬虫草或其培养物被本发明用作首选原料, 经试验证明, 加入八角, 对其效果有显著促进作用。 杜仲叶粉: 用于鹿饲料, 使用后鹿的抗病力增 强, 加快了生长速度。 松针粉: 加入鹿饲料, 可使其缩短生长期, 减少耗 料量,降低饲料成本。其一般配比为灵芝或其培养物(灵芝菌丝体)在 1 -- 15 克范围、虫草或其培养物(虫草菌丝体)在 1- - 20克范围的比例配合,在 60 度下低温干燥使其含水率在 8-10%以下, 混合、粉碎过 120目筛即可获得理 想的产品。 其优选配比为: 由灵芝或其培养物 5—15克范围、 虫草其培养 物 5— 20克范围的比例配合, 在 60度以下低温干燥使其含水率在 8-10%以 下, 混合、 粉碎制成。 经试验证明, 加入八角, 对其效果有显著促进作用。 其配比为杨树叶或灵芝或其培养物(灵芝菌丝体) 5- -15克范围、 虫草或其 培养物 (虫草菌丝体) 5- -20克范围、 八角 0. 5- -1克范围的比例配合。 The formula selection principle of the green and environmentally-friendly livestock feed additive of the invention can be obtained by compounding compound or natural material (including animal, plant and microbial materials). It can be prepared by mixing plant cellulose, hemicellulose, lignin, physiologically active ganoderma lucidum or its culture products. It is also possible to use one or more kinds of plants or Chinese herbal medicines containing triterpenoids and polysaccharides. Or fungi, using existing The technology is prepared by preparation; it can also be prepared by using existing biotechnology fermentation engineering. It is an excellent product obtained by processing Chinese herbal medicine Ganoderma lucidum or its culture, Cordyceps militaris or its culture. Ganoderma lucidum or its culture is one of the few compounds containing physiologically active triterpenoids and polysaccharides; Cordyceps or its culture is rich in polysaccharides. Ganoderma lucidum triterpenoids, polysaccharides and cordyceps polysaccharides, as well as many nucleosides, furans, alcohols, alkaloids, proteins, amino acids and other physiologically active compounds and trace elements, have been proven by modern science, so Ganoderma lucidum or its culture The product, Cordyceps militaris or its culture is used as the preferred raw material by the present invention, and it has been experimentally proved that the addition of the star anise has a significant effect on the effect. Eucommia leaf powder: For deer feed, the deer's disease resistance is enhanced and the growth rate is accelerated. Pine needle powder: Adding deer feed can shorten the growth period, reduce the consumption and reduce the feed cost. The general ratio is Ganoderma lucidum or its culture (Ganoderma lucidum mycelium) in the range of 1 - 15 g, Cordyceps or its culture (Cytotheca mycelium) in the range of 1 - 20 g, at 60 ° It is dried at a low temperature to have a water content of 8-10% or less. It can be mixed and pulverized through a 120 mesh sieve to obtain an ideal product. The preferred ratio is: a range of 5-15 g of Ganoderma lucidum or its culture, and a range of 5-20 g of Cordyceps militaris culture, and drying at a low temperature of 60 degrees or less to make the water content below 8-10%, mixing Made by crushing. It has been proved by experiments that the addition of star anise has a significant effect on its effect. The ratio is Yang leaves or Ganoderma lucidum or its culture (Ganoderma lucidum mycelium) 5--15 g range, Cordyceps or its culture (Cytotheca mycelium) 5--20 g range, octagonal 0. 5- -1 The proportion of the gram range is matched.
本发明的绿色环保畜禽饲料添加剂的配方, 其配方特征在于: 其配方 组份主要为灵芝或其培养物或杨树叶、 冬虫草或其培养物、 杜仲叶或金银 花、 八角粉、 松针粉、 何首乌、 生地等构成, 其配方各自份量只要大于零 即可。 其配方优选为: 主要由灵芝或其培养物或杨树叶 5— 15份、 冬虫草 或其培养物 1一 20份、 杜仲叶或金银花 1一 5份、 八角粉 0. 5—1份、 松针 或松针粉 1一 5份; 加入何首乌、 生地、 人参可获得最佳效果。 优选为何首 乌 1一 2份、 生地 1一 2份、 人参 1一 20份。 人参优选为 5— 15份。 即: 本 发明的绿色环保畜禽词料添加剂优选最佳配方为: 以绝干重量计, 主要由 灵芝或其灵芝培养物或杨树叶 5— 15份、 冬虫草或其冬虫草培养物 1一 20 份、 杜仲叶或金银花 1一 5份、 八角或八角粉 0. 5— 1份、 松针粉 1一 5份、 何首乌 1一 2份、 生地 1一 2份、 人参 1一 20份构成。 可优选为主要由灵芝 或其灵芝培养物或杨树叶 5— 15份、 冬虫草或其冬虫草培养物 5— 20份、 杜仲叶或金银花 1一 5份、 八角或八角粉 0. 5-1份、 松针粉 1一 5份、 何首
乌 1一 2份、 生地 1一 2份、 人参 1一 20份构成。 最优选为主要由灵芝或其 灵芝培养物或杨树叶 5— 15份、 冬虫草或其冬虫草培养物 1一 5份、 杜仲叶 或金银花 1一 5份、 八角或八角粉 0. 5— 1份、松针粉 1一 5份、 何首乌 1一 2 份、 生地 1一 2份、 人参 1一 20份构成。 The formula of the green environmental protection livestock feed additive of the invention is characterized in that: the formula component is mainly ganoderma lucidum or its culture or poplar leaves, cordyceps or its culture, Eucommia ulmoides or honeysuckle, octagonal powder, pine needle powder, Polygonum multiflorum, raw land, etc., the weight of each formula can be as long as it is greater than zero. Preferably, the formulation is: 5 to 15 parts of Ganoderma lucidum or its culture or poplar leaves, 1-20 parts of Cordyceps or its culture, 1 to 5 parts of Eucommia ulmoides or honeysuckle, 0.5 to 1 part of octagonal powder, pine needles Or 1 to 5 servings of pine needle powder; adding Polygonum, ginseng and ginseng for best results. Preferably, 1 to 2 parts of Shouwu, 1 to 2 parts of raw land, and 1 to 20 parts of ginseng. The ginseng is preferably 5-15 parts. Namely: the optimal formulation of the environmentally friendly livestock and poultry word additive of the present invention is: based on the absolute dry weight, mainly consisting of Ganoderma lucidum or its Ganoderma lucidum culture or 5-15 parts of poplar leaves, Cordyceps sinensis or its Cordyceps sinensis culture 1 20 parts, eucalyptus leaves or honeysuckle 1-5, octagonal or octagonal powder 0.5 to 1 serving, pine needle powder 1 to 5, Polygonum 1-2, 1 to 2, and ginseng 1 to 20. Preferably, it is preferably 5-15 parts of Ganoderma lucidum or its Ganoderma lucidum culture or poplar leaves, 5-20 parts of Cordyceps sinensis or its Cordyceps sinensis culture, 1-5 parts of Eucommia ulmoides or honeysuckle, octagonal or octagonal powder 0. 5-1 1 part, 5 parts of pine needle powder, Heshou 1 to 2 parts of Wu, 1 to 2 parts of raw land, and 1 to 20 parts of ginseng. The most preferred is mainly 5 to 15 parts of Ganoderma lucidum or its Ganoderma lucidum culture or poplar leaves, 1 to 5 parts of Cordyceps sinensis or its Cordyceps sinensis culture, 1-5 parts of Eucommia ulmoides or honeysuckle, octagonal or octagonal powder 0. 5-1 1 part, 1 part of pine needle powder, 1 2 parts of Polygonum multiflorum, 1 2 parts of raw land, 1-20 parts of ginseng.
本发明的绿色环保畜禽饲料添加剂的材料组配的各材料特征及选用依 据: The material characteristics and selection basis of the materials of the green environmental protection livestock feed additive of the invention are as follows:
1、 灵芝或其培养物,灵芝是中国中医药宝库中的珍品, 素有 "仙草 "之 誉。 古今药理与临床研究均证明, 灵芝确有防病治病、 延年益寿之功效。 东汉时期的 《神农本草经》、 明代著名医药学家李时珍的 《本草纲目》, 都 对灵芝的功效有详细的极为肯定的记载。 现代药理学与临床实践进一步证 实了灵芝的药理作用, 并证实灵芝多糖是灵芝扶正固本、 滋补强壮、 延年 益寿的主要成分。 无毒副作用, 可以药.食两用。 临床试验也证实, 灵芝多 糖可作为肿瘤化学治疗和放射治疗的有效辅助治疗药。 灵芝或其培养物化 学成分有: 三萜类化合物、 多糖类、 核苷类、 醇类、 生物碱类、 呋喃衍 生物、 氨基酸多肽类、 无机元素、 脂肪酸等。 主要有效成分为三萜类化合 物、 多糖类。 现已证明, 灵芝三萜类化合物、 多糖类具有抗肿瘤作用、 免 疫调节作用、 降血糖作用、 降血脂作用、 抗氧化作用和抗衰老作用, 故灵 芝多糖类是灵芝的主要有效成分。 何首乌具有返老还童之功。 1. Ganoderma lucidum or its culture, Ganoderma Lucidum is a treasure in the treasure house of Chinese medicine, and is known as the "Xiancao". Ancient and modern pharmacological and clinical studies have proved that Ganoderma lucidum does have the effect of preventing and curing diseases and prolonging life. The "Shen Nong's Materia Medica" in the Eastern Han Dynasty and the "Compendium of Materia Medica" by the famous medical scientist Li Shizhen of the Ming Dynasty all have a very detailed record of the efficacy of Ganoderma lucidum. Modern pharmacology and clinical practice further confirmed the pharmacological effects of Ganoderma lucidum, and confirmed that Ganoderma lucidum polysaccharide is the main component of Ganoderma lucidum to strengthen the body, nourish and strengthen, and prolong life. No toxic side effects, can be used for medicine. Clinical trials have also confirmed that Ganoderma lucidum polysaccharides can be used as an effective adjuvant therapy for tumor chemotherapy and radiation therapy. The chemical constituents of Ganoderma lucidum or its culture are: triterpenoids, polysaccharides, nucleosides, alcohols, alkaloids, furan derivatives, amino acid polypeptides, inorganic elements, fatty acids, and the like. The main active ingredients are triterpenoid compounds and polysaccharides. It has been proved that Ganoderma lucidum triterpenoids and polysaccharides have anti-tumor effects, immunomodulatory effects, hypoglycemic effects, hypolipidemic effects, antioxidant effects and anti-aging effects, so Ganoderma lucidum polysaccharides are the main active constituents of Ganoderma lucidum. Polygonum has the power to rejuvenate.
2、 冬虫草或其培养物: 2. Cordyceps or its culture:
' 据中国传统医学, 冬虫夏草是一种滋补强壮药, 其味甘, 性平, 入肺 经、 肾经, 具有益肺肾、 止咳嗽、 补虛损、 补血、 益精气的功能, 现代研 究发现, 冬虫夏草中含有丰富的蛋白质,其中富含 "虫草多肽" 。 虫草肽含 有六种环二肽类化合物, 这些化合物具有抗肿瘤与增强免疫的生理活性结 构, 且虫草肽中还含有虫草素、 腺苷、 腺瞟吟、 尿苷等核苷类物质和大量 维生素、 矿物质和微量元素。 有关专家认为: 虫草多肽功能齐全、 作用大、 起效快, 是一种最新型、 高效、 广谱的抗肿瘤功能肽, 它不仅能对癌细胞 有直接杀伤作用, 同时还能明显增强机体的免疫功能, 其功能并效果显示 是所有综合保健、 治疗功能。 冬虫夏草中还含有丰富的脂肪、 粗纤维、 碳 水化合物、 多种维生素、 虫草素、 虫草酸、 多种氨基酸及铁、 磷、 钙、 锌、 锰、 硒等人体必需的元素。 有效成分主要是虫草多糖, 该多糖是由甘露糖、
虫草素、 腺苷、 半乳糖、 ***糖、 木糖精、 葡萄糖、 岩藻糖组成的多聚 糖。 实验证明, 虫草多糖可提高人体免疫功能, 升高白细胞, 临床已用于 治疗恶性肿瘤。 According to traditional Chinese medicine, Cordyceps sinensis is a nourishing and strong medicine. Its sweetness, flatness, and into the lungs and kidneys have the functions of benefiting the lungs and kidneys, relieving cough, supplementing the deficiency, supplementing the blood, and benefiting the essence. Modern research It was found that Cordyceps sinensis is rich in protein, which is rich in Cordyceps polypeptide. Cordyceps peptide contains six cyclic dipeptide compounds, which have physiologically active structures against tumors and enhance immunity, and Cordyceps peptides also contain nucleosides such as cordycepin, adenosine, adenine, uridine and a large number of vitamins. , minerals and trace elements. Experts believe that: Cordyceps polypeptide is a new, high-efficiency, broad-spectrum anti-tumor functional peptide with complete functions, large effect and fast onset. It not only has direct killing effect on cancer cells, but also significantly enhances the body's body. Immune function, its function and effect display is all comprehensive health care, treatment function. Cordyceps sinensis is also rich in fat, crude fiber, carbohydrates, multivitamins, cordycepin, cordycepic acid, various amino acids and essential elements such as iron, phosphorus, calcium, zinc, manganese and selenium. The active ingredient is mainly Cordyceps polysaccharide, which is made up of mannose, A polysaccharide consisting of cordycepin, adenosine, galactose, arabinose, xylose, glucose, and fucose. Experiments have shown that Cordyceps polysaccharide can improve human immune function, increase white blood cells, and has been used clinically to treat malignant tumors.
3、 八角: 3, octagonal:
木兰科植物八角茴香 Illicium verum Hook. f. 的干燥果实, 其含有效 成分是复杂的芳香油, 其主要成分是反式大茴香脑。 还含有 α —蒎烯、 柠 檬烯、 芳樟醇、 4一萜品醇、 草蒿脑、 茴香醛等成分。 茴香油在医药工业中 是合成阴性激素已垸雌酚的主要原料。 Illicium verum Hook. f. The dried fruit, which contains the active ingredient is a complex aromatic oil, whose main component is trans anise. It also contains ingredients such as α-pinene, liminene, linalool, 4-terpineol, artemisia, and anisaldehyde. In the pharmaceutical industry, fennel oil is the main raw material for the synthesis of the negative hormone erythromycin.
4、 杜仲叶 4, Eucommia leaves
杜仲为杜仲科杜仲属植物 Eucommia ulmoides Ol iv.,传统以皮入药, 味甘、 性温,归肝、 肾经,具有补肝肾、 强筋骨、 安胎的功效,是一种名贵滋 补药材。 近来研究证实杜仲叶和皮成分基本相同, 且叶中绿原酸 CHA含量 明显高于皮。 Eucommia ulmoides Ol iv. is a traditional Chinese medicine for Eucommia ulmoides Ol iv. It is traditionally used as a medicine. It is sweet, warm, and has liver and kidney. It has the functions of nourishing liver and kidney, strengthening bones and strengthening the fetus. It is a valuable nourishing medicine. Recent studies have confirmed that the leaves and skin components of Eucommia ulmoides are basically the same, and the CHA content of chlorogenic acid in leaves is significantly higher than that in the skin.
杜仲叶中含杜仲胶、 多糖、 黄酮、 松脂醇二葡萄糖苷、 桃叶珊瑚苷、 京尼平苷、 苯丙素类化合物、 绿原酸、 芸香甙、 香豆素、 槲皮素、 山柰醇、 及其环烯醚萜类和木脂素类等次生代谢产物, 丁香脂素二糖甙 (SGD),京尼 平甙酸 (GA)化合物等多种活性化学成分, 含有 17种氨基酸和 20多种微量 元素, 营养十分丰富。 其中氯原酸(chlorogenic acid, CHA)是名贵补益中 药杜仲的主要活性成分之一, 对多种致病菌和病毒有较强的抑制和杀灭作 用, 是中成药抗菌解毒、 补中益气、 镇痛强志、 消炎利胆的主要有效成份. Eucommia ulmoides contains gutta percha, polysaccharide, flavonoids, rosinol diglucoside, arachidin, genipin, phenylpropanoids, chlorogenic acid, musk, coumarin, quercetin, hawthorn Secondary active metabolites such as alcohols, their iridoids and lignans, sucrose disaccharide (SGD), genipin (GA) compounds, etc., containing 17 amino acids. With more than 20 kinds of trace elements, the nutrition is very rich. Among them, chlorogenic acid (CH) is one of the main active ingredients of the valuable Chinese herbal medicine Eucommia ulmoides Oliv. It has strong inhibition and killing effect on various pathogenic bacteria and viruses. It is an antibacterial and detoxification of Chinese patent medicines. 3. The main active ingredient of analgesic and anti - inflammatory and choleretic.
5、 松针粉: 5, pine needle powder:
松针粉含粗蛋白质 12. 96%, 粗脂肪 11. 1%, 粗纤维 27. 1%, 无氮浸出物 41. 5%, 灰分 3. 43%、 维生素 A含量为 950〜2203my/kg, 还含有丰富的维生 素(、 维生素 E和硒元素。 维生素 A、 维生素 E、 维生素 C都与机体的免疫 '力有密切关系和重要作用。例如维生素 E能增强体液免疫反应,提高辅助 T 细胞数量, 使机体免疫力提高, 硒与维生素 E有协同作用, 可促进抗体形 成, 增强机体免疫力和抗病力。 松针粉中含有的植物激素、 植物杀菌素可 杀死机体内有害微生物。 加入鹿饲料, 可使其缩短生长期, 减少耗料量, 降低伺料成本。 Pine needle powder containing crude protein 12.96%, crude fat 11.1%, crude fiber 27.1%, nitrogen-free extract 41. 5%, ash 3. 43%, vitamin A content 950~2203my/kg, also Rich in vitamins (, vitamin E and selenium. Vitamin A, vitamin E, and vitamin C are closely related to the body's immunity. For example, vitamin E can enhance humoral immune response and increase the number of helper T cells. The body's immunity is improved, and selenium and vitamin E have a synergistic effect, which can promote the formation of antibodies and enhance the body's immunity and disease resistance. The plant hormones and phytoncides contained in pine needle powder can kill harmful microorganisms in the body. It can shorten the growth period, reduce the consumption of materials, and reduce the cost of feeding.
6、 何首乌 Polygonum multiflorum Thunb., 又名赤首乌、 地精。
为多年生缠绕藤本。 根细长, 末端成肥大的块根, 外表红褐色至暗褐色。 茎基部略呈木质, 中空。 叶互生, 具长柄, 叶片狭卵形或心形, 先端渐尖, 基部心形或箭形, 全缘或微带波形, 上面深绿色, 下面浅绿色, 光滑无毛。 何首乌块根含大黄素、 大黄酚、 大黄素甲醚等蒽醌类、 乙酰苯甙等化合物 和白藜芦醇、 云杉新甙等, 还含没食子酸、 右旋儿茶精、 右旋表儿茶精等 化合物。 具有养血滋阴, 润肠通便, 截疟, 祛风, 解毒。 主治血虚头暈目 眩、 心悸、 失眠, 肝肾阴虚之腰膝酸软、 须发早白、 耳鸣、 遗精、 肠燥便 秘, 久疟体虚, 风疹瘙痒, 疮疡, 瘰疬。 夜交藤: 养心安神, 祛风, 通络。 主治失眠, 多梦, 血虚身痛, 肌肤麻木, 风湿痹痛, 风疹瘙痒等。 6, Polygonum Polygonum multiflorum Thunb., also known as Chishouwu, goblin. Wrapped vines for perennial life. The roots are slender, and the ends are hypertrophic, with a reddish brown to dark brown appearance. The base of the stem is slightly woody and hollow. Leaves alternate, long-handed, leaf blade narrowly ovate or urate, apate acuminate, base sate or sateate, entire or microsulate, succulously succulous. Polygonum multiflorum root contains emodin, chrysophanol, emodin methyl ether and other steroids, acetophenone and other compounds and resveratrol, spruce, etc., also contains gallic acid, dextrogal tea, right-handed Compounds such as tea essence. It has nourishing blood, nourishing yin, laxative, malaria, hurricane, detoxification. Indications of blood deficiency, dizziness, palpitations, insomnia, liver and kidney yin deficiency, waist and knees, must be white, tinnitus, nocturnal emission, intestinal dry constipation, long-lasting malaria, rubella itching, sores, phlegm. Night delivery vine: nourish the heart and calm the nerves, hurricane, and collaterals. Indications of insomnia, more dreams, bloody body pain, skin numbness, rheumatism and pain, rubella itching and so on.
7、 生地 Radix Rehmanniae (英) Chinese Fox -Glove Root 别名 地黄、 酒壶花、 怀庆地黄、 山烟、 山烟、 山白菜。 为玄参科植物怀庆地黄 [Rehmannia glutinosa (Gaerin) Libosch. f . huelchingensis (Chao et Schih) Hsiao] ], 以块茎入药。 鲜地黄: 清热、 生津、 凉血; 生地黄: 清 热、 生津、 润燥、 滑肠、 破瘀、 生新、 止痛、 调经、 金疮瘀、 凉血、 止血; 熟地黄: 滋阴补肾、 调经补血、 血虚头痛、 肝痛。 原主产于河南省温县、 孟县、 武陵、 博爱、 沁阳等县, 现全国各省、 自治区几乎都有引种栽培。 鲜地黄 清热生津, 凉血, 止血。 用于热病伤阴, 舌绛烦渴, 发斑发疹, 吐 血, 衄血, 咽喉肿痛。 生地黄 清热凉血, 养阴, 生津。 用于热病舌绛烦 渴, 阴虚内热, 骨蒸劳热, 内热消渴, 吐血, 衄血, 发斑发疹。 主要含梓 醇 (catalpol )、 多种氨基酸和糖、 甘露醇、 β -谷甾醇及菜油甾醇 7, the birthplace Radix Rehmanniae (English) Chinese Fox -Glove Root Alias Rehmannia, jug flower, Huaiqing Dihuang, mountain smoke, mountain smoke, mountain cabbage. For the Scrophulariaceae plant Rehmannia glutinosa (Gaerin) Libosch. f. huelchingensis (Chao et Schih) Hsiao]], the tuber is used as a medicine. Fresh Rehmannia: Qingre, Shengjin, Liangxue; Rehmannia glutinosa: heat, Shengjin, Runzao, slippery, sputum, new, analgesic, menstruation, golden sore, cool blood, hemostasis; Rehmannia glutinosa: nourishing yin and tonifying kidney, regulating menstruation , blood deficiency headache, liver pain. It was originally produced in Wenxian County, Mengxian County, Wuling, Boai, Fuyang and other counties in Henan Province. Now almost all provinces and autonomous regions in China have introduced and cultivated. Fresh rehmannia, heat and fluid, cool blood, stop bleeding. For fever, yin, tongue and thirst, hair spot and rash, vomiting blood, blood stasis, sore throat. Rehmannia glutinosa, heat and cool blood, nourishing yin, Shengjin. For fever, tongue irritability, yin deficiency heat, bone steaming heat, internal heat, thirst, vomiting blood, blood stasis, hair spot and rash. Mainly containing sterols (catalpol), various amino acids and sugars, mannitol, β-sitosterol and campesterol
( campesterol ) 等化合物。 (camesterol) and other compounds.
8、 人参 (Panax. Ginseng C. A. Meyer) 显为人知, 来源于五加科人参, 人参是五加科植物人参的干燥根。 在我国, 食用人参已有很长的历史, 早 在 《神农本草经》里就将它列为上品。 据国内外药学工作者对人参各部位 进行的大量研究表明, 人参的化学成分比较复杂, 但一致认为人参活性成 分为人参皂苷, 目前已经分离人参皂苷有 20多种。此外人参还含有氨基酸、 肽多糖、 维生素、 脂肪酸与甾醇、 挥发油、 黄酮、 酵素、 磷脂、 无机化合 物等成分。 人参具有大补元气, 滋补强壮, 安神益智, 生津, 复脉固脱等 功效。 现代医学普遍认为人参对中枢神经***、 心血管***、 消化***、 免疫***、 内分泌***、 泌尿生殖***有广泛的作用, 从而可提高人体力、
智力的活动能力, 增强机体对有害刺激的非特异性抵抗力。 人参的药理活 性常因机体机能状态不同双向作用。 8. Panax. Ginseng CA Meyer is well known. It is derived from the ginseng of Araliaceae, which is the dry root of the ginseng of the Araliaceae plant. In China, the consumption of ginseng has a long history, and it has been listed as a top grade in the Shennong Bencao Classic. According to a large number of studies conducted by pharmacists at home and abroad on various parts of ginseng, the chemical composition of ginseng is more complicated, but it is agreed that the active ingredient of ginseng is ginsenoside, and there are more than 20 kinds of ginsenosides. In addition, ginseng also contains amino acids, peptide polysaccharides, vitamins, fatty acids and sterols, volatile oils, flavonoids, enzymes, phospholipids, inorganic compounds and other ingredients. Ginseng has great vitality, nourishing and strong, soothing and refreshing, Shengjin, Fumai Gutie and so on. Modern medicine generally believes that ginseng has a wide range of effects on the central nervous system, cardiovascular system, digestive system, immune system, endocrine system, and genitourinary system, thereby improving human body strength. The ability of intellectual activity to enhance the body's non-specific resistance to noxious stimuli. The pharmacological activity of ginseng is often caused by two-way effects of different functional states of the body.
本发明的绿色环保畜禽饲料添加剂, 可采用现有技术方法制备粉状或 粒状产品。 一般可在 75度下低温干燥使其含水率在 8-12%以下, 混合、 粉 碎过 120目筛即可获得理想的粉状产品。 The green environmentally-friendly livestock and poultry feed additive of the present invention can be prepared into a powdery or granular product by a prior art method. Generally, it can be dried at a low temperature of 75 °C to have a water content of 8-12% or less. Mixing and pulverizing through a 120 mesh sieve can obtain a desired powdery product.
本发明的绿色环保畜禽饲料添加剂在饲料中的使用添加量, 一般以重量 计在 0. 1-- 5%范围选择为宜, 多加仅是成本上升而已。 The use amount of the green and environmentally-friendly livestock and poultry feed additive of the present invention in the feed is generally selected in the range of 0.1 to 5% by weight, and the addition is only the cost increase.
本发明的绿色环保畜禽伺料添加剂的制备方法, 特征在于: 主要原料 组份: 灵芝或其培养物或杨树叶、 冬虫草或其培养物、 杜仲叶或金银花、 八角粉、 松针粉分别在 60--7CTC下干燥至含水量在 8—12%范围, 经分别粉 碎后, 按配方 (以绝干重量计), 灵芝或其灵芝培养物或杨树叶 5— 15份、 冬虫草或其冬虫草培养物 5— 20份、杜仲叶或金银花 1一 5份、八角粉 0. 5—1 份、 松针粉 1—5份、 何首乌 1一 2份、 生地 1一 2份、 人参 1一 20份混合均 匀, 即为成品。 也可再进而造粒加工获得颗粒产品。 其优选配方为: 主要 由灵芝或其培养或杨树叶物 5— 15份、 冬虫草或其培养物 5— 20份、 杜仲 叶或金银花 1—5份、 八角粉 0. 5—1份、 松针粉 1一 5份、 何首乌 1一 2份、 生地 1一 2份、 人参 1一 5份组合而构成。 也可根据需要添加一些辅助性或 配合材料。 加入磷酸氢钙、 鱼骨粉、 胺基酸可构成高钙高蛋白伺料添加剂; 与碳水化合物配合, 可构成绿色环保伺料; 与磷酸氢钙、 鱼骨粉、 胺基酸、 碳水化合物配合, 可构成绿色环保高钙高蛋白精词料。 The preparation method of the green environmental protection livestock feed additive of the invention is characterized by: main raw material components: ganoderma lucidum or its culture or poplar leaves, cordyceps or its culture, Eucommia ulmoides or honeysuckle, octagonal powder, pine needle powder respectively Dry at 60--7CTC until the water content is in the range of 8-12%. After crushing separately, according to the formula (based on the dry weight), Ganoderma lucidum or its Ganoderma lucidum culture or Yang leaves 5-15 parts, Cordyceps or its winter 5-20 parts of Cordyceps culture, 1-5 parts of Eucommia ulmoides or honeysuckle, 0.5-1 parts of octagonal powder, 1-5 parts of pine needle powder, 1-2 parts of Polygonum multiflorum, 1-2 parts of raw land, 1-20 parts of ginseng Mix evenly, which is the finished product. The granulation product can also be obtained by granulation. The preferred formula is: 5-15 parts of Ganoderma lucidum or its culture or poplar leaves, 5-20 parts of Cordyceps or its culture, 1-5 parts of Eucommia ulmoides or honeysuckle, 0.5-1 parts of octagonal powder, pine needles 1 to 5 parts of powder, 1 to 2 parts of Polygonum multiflorum, 1 to 2 parts of raw land, and 1 to 5 parts of ginseng are combined. Additional auxiliary or mating materials can also be added as needed. Adding calcium hydrogen phosphate, fish bone meal, amino acid can form a high calcium high protein feed additive; combined with carbohydrates, can constitute a green environmental protection; with calcium hydrogen phosphate, fish bone meal, amino acid, carbohydrate, can It constitutes a green, high-calcium, high-protein substance.
本发明的绿色环保畜禽饲料添加剂,加入磷酸氢钙、 鱼骨粉、 胺基酸可 构成高钙高蛋白词料添加剂, 特征在于: 由 、 B两部分组成; 配比为, A: B为 1 : 1. 5— 2. 5范围。 The green environmental protection livestock feed additive of the invention, adding calcium hydrogen phosphate, fish bone powder and amino acid can constitute a high calcium high protein word additive, characterized by: consisting of two parts, B; the ratio is, A: B is 1 : 1. 5 - 2. 5 range.
A组配方组成: 以绝干重量计, 为灵芝或其培养物或杨树叶 5- 15份, 冬虫草或其培养物 5-20份, 杜仲叶或金银花 1-5份, 八角粉 0. 5~1份, 松针粉 1-5份, 何首乌 1一 2份、 生地 1一 2份、 人参 1一 5份。 其优选为配 方,其特征在于:以绝干重量计,主要由灵芝或其灵芝培养物或杨树叶 5— 15 份、 冬虫草或其冬虫草培养物 5— 20份、 杜仲叶或金银花 1一 5份、 八角粉 0. 5—1份、松针粉 1—5份、 何首乌 1—2份、 生地 1一 2份、 人参 1一 20份 构成。
B组配方组成: 以绝干重量计, 骨粉 30— 50份, 含蛋白质的动植物材 料 50— 80份(如鱼粉、大豆粉、生物蛋白质等),钙磷矿物质或贝壳粉 0— 20 份。 The composition of the group A is: based on the absolute dry weight, for the Ganoderma lucidum or its culture or Yang leaves 5-15 parts, Cordyceps or its culture 5-20 parts, Eucommia leaves or honeysuckle 1-5, octagonal powder 0. 5 ~1 serving, 1-5 servings of pine needle powder, 1 to 2 portions of Polygonum multiflorum, 1 to 2 portions of raw land, and 1 to 5 parts of ginseng. It is preferably a formulation characterized by being mainly composed of Ganoderma lucidum or its Ganoderma lucidum culture or 5-15 parts of poplar leaves, 5-20 parts of Cordyceps or its Cordyceps culture, Eucommia ulmoides or honeysuckle 1 5 parts, octagonal powder 0.5 to 1 part, pine needle powder 1-5 parts, Polygonum 1-2 parts, raw ground 1 2 parts, ginseng 1-20 parts. Group B formula: 30-50 parts of bone powder, 50-80 parts of animal and plant materials containing protein (such as fish meal, soy flour, biological protein, etc.), calcium phosphate mineral or shell powder 0-20 parts .
本发明的绿色环保畜禽饲料添加剂,加入磷酸氢钙、 鱼骨粉、 胺基酸、 碳水化合物可构成绿色环保高钙高蛋白精饲料, 特征在于: A、 B两部分 组成; 配比为, A: B为 1 : 6. 5— 35范围。 A组配方组成: 以绝干重量计, 为灵芝或其培养物 5-15份, 冬虫草或其培养物 5 20份, 杜仲叶 1-5份, 八角粉 0. 5—1份, 松针粉 1-5份, 何首乌 1一2份、 生地 1一 2份、 人参 1 一 5份。 其优选为配方, 其特征在于: 以绝干重量计, 主要由灵芝或其灵芝 培养物或杨树叶 5— 15份、 冬虫草或其冬虫草培养物 5— 20份、 杜仲叶或 金银花 1一 5份、 八角粉 0. 5—1份、 松针粉 1—5份、 何首乌 1一 2份、 生 地 1一 2份、 人参 1一 20份构成。 The green environmental protection livestock feed additive of the invention adds calcium hydrogen phosphate, fish bone meal, amino acid and carbohydrate to form a green high-calcium high-protein concentrate feed, characterized by: A and B are composed of two parts; the ratio is A : B is 1: 6. 5 - 35 range. Composition of group A: 5-15 parts of Ganoderma lucidum or its culture, 5 20 parts of Cordyceps sinensis or its culture, 1-5 parts of Eucommia ulmoides, 0. 5-1 parts of octagonal powder, pine needle powder 1-5 parts, 1 to 2 copies of Polygonum multiflorum, 1 to 2 copies of raw land, and 1 to 5 parts of ginseng. It is preferably a formulation characterized by: on a dry weight basis, mainly consisting of Ganoderma lucidum or its Ganoderma lucidum culture or 5-15 parts of poplar leaves, Cordyceps or its Cordyceps culture 5-20 parts, Eucommia ulmoides or honeysuckle 1 5 parts, octagonal powder 0.5 to 1 part, pine needle powder 1-5 parts, Polygonum multiflorum 1 2, raw ground 1 2 parts, ginseng 1-20 parts.
B组配方组成: 以绝干重量计, 骨粉 30— 50份, 含蛋白质的动植物材 料 50— 80份(如鱼粉、大豆粉、生物蛋白质等),钙磷矿物质或贝壳粉 0— 20 份, 碳水化合物类植物材料 350- -950份 (如淀粉类的大米粉、 面粉、 玉米' 粉、 麦皮麦糠、 薯类等)。 Group B formula: 30-50 parts of bone powder, 50-80 parts of animal and plant materials containing protein (such as fish meal, soy flour, biological protein, etc.), calcium phosphate mineral or shell powder 0-20 parts , 350-950 parts of carbohydrate plant material (such as starchy rice flour, flour, corn 'powder, wheat bran, potato, etc.).
本发明的绿色环保畜禽词料添加剂, 可广泛地适用于喂养各种畜禽类 饲料的添加剂; 本发明还要特此说明其用途是, 特别适用作鹿词料添加剂, 不仅对其生长有特别的显著效果, 优其是对其鹿茸的产量和质量有非常大 的提高。 因此本发明的绿色环保畜禽饲料添加剂, 可作为鹿词料特效添加 剂或专用鹿饲料添加剂。 The environmentally-friendly livestock and poultry word additive of the invention can be widely applied to additives for feeding various livestock and poultry feeds; the invention also clarifies that its use is particularly suitable for the deer material additive, not only for its growth, but also for its growth. The remarkable effect is that it has a very large increase in the yield and quality of its antler. Therefore, the green environmentally-friendly livestock and poultry feed additive of the present invention can be used as a special additive for deer materials or a special deer feed additive.
本发明与现有技术相比具有如下优点和效果: Compared with the prior art, the invention has the following advantages and effects:
1、 采用原料为纯天然材料, 为环保无污染绿色产品; 1. The raw materials are pure natural materials, which are environmentally friendly and pollution-free green products;
2、 畜禽词料添加剂使用添加量少, 畜禽生长快 10- -20%; 2. The use of animal and poultry word additives is less, and the growth of livestock and poultry is 10-20% faster;
3、 抗病力强; 3. Strong disease resistance;
4、 繁殖率高等优点; 4. High reproductive rate;
5、 在用作鹿伺料添加剂, 可使仔鹿生长快, 茸鹿产茸量提高, 母鹿怀 胎率提高, 茸鹿膘情持久, 抗病能力强, 肉质滑嫩, 口感鲜美, 营养丰富, 没有药物残留污染。 经试验对比, 具体数据如下- A、 仔鹿生长速度快, 增重率约 11%;
B、 鹿茸产量提高约 13%; 5, used as a deer feed additive, can make the deer grow fast, the velvet deer antlers increase, the doe pregnancy rate increases, the velvet deer lasts, the disease resistance is strong, the meat is smooth, the taste is delicious, nutritious, no Drug residue contamination. Through experimental comparison, the specific data are as follows - A, the growth rate of the deer is fast, the weight gain rate is about 11%; B. The production of antler is increased by about 13%;
C、 母鹿怀胎率提高约 8%; C, the mother's pregnancy rate increased by about 8%;
D、 抗病能力提高约 10%; D, the disease resistance increased by about 10%;
E、 梅花鹿的毛色更艳亮; E, the color of the sika deer is more bright;
F、 提高了鹿茸、 鹿肉产品的品质, 以麂茸为例, 活性钙及 SOD (超氧 化物歧化敏)、 硒的含量有所提高, 可以帮助人体抗衰老, 延年益寿。 中国 广州分析测试中心的检测报告表明: 四叉新鲜茸中 SOD活性含量为 40U/g, 活性钙为 7. 5 X 102mg/100g, 硒为 0. l lmg/kg c F. Improve the quality of antler and venison products. Taking velvet antler as an example, the content of active calcium and SOD (superoxide dismutation) and selenium is improved, which can help the body to resist aging and prolong life. The test report of the Guangzhou Analytical Testing Center of China shows that: the active content of SOD in the four-pronged fresh velvet is 40 U/g, the active calcium is 7. 5 X 10 2 mg/100 g, and the selenium is 0. l lmg/kg c
具体实施方式 detailed description
下面结合实施例对本发明的技术方案进一步详细描述, 但本发明的实 施方式不限于此。 枫树叶或树枝 20克, 猴头菌 (菇) 20克, 八角 0. 5克, 在 60度下低温 干燥使其含水率在 8- 10%以下, 混合、 粉碎过 120目筛即为产品。 检测: 醇 提取物(三萜类物质等)含量为 1. 5-1. 6%左右;氷提取物(多糖类物质等) 含量为 7- -8%左右。 The technical solution of the present invention will be further described in detail below with reference to the embodiments, but the embodiments of the present invention are not limited thereto. Maple leaves or branches 20 grams, Hericium erinaceus (mushroom) 20 grams, octagonal 0. 5 grams, dried at a low temperature of 60 degrees to make the water content below 8- 10%, mixed, crushed through 120 mesh sieve is the product. Detection: The content of alcohol extract (triterpenoids, etc.) is about 1.5-1.6%; the content of ice extract (polysaccharide, etc.) is about 7-8%.
实施例 2 Example 2
杨树叶或树枝 20克, 猴头菌 (菇) 20克, 八角 0. 5克, 在 60度下低温 干燥使其含水率在 8- 10%以下, 混合、 粉碎过 120目筛即为产品。 检测: 醇 提取物(三萜类物质等)含量为 1. 4-1. 5%左右; 水提取物(多糖类物质等) 含量为 8- -9%左右。 Poplar leaves or branches 20 grams, Hericium erinaceus (mushroom) 20 grams, octagonal 0. 5 grams, dried at a low temperature of 60 degrees to make the water content below 8- 10%, mixed, crushed through 120 mesh sieve is the product. Detection: The content of alcohol extract (triterpenoids, etc.) is 1. 4-1. 5%; the content of water extract (polysaccharide, etc.) is about 8-9%.
实施例 3 Example 3
灵芝 15克, 虫草 20克, 八角 0. 5克, 在 60度下低温干燥使其含水率 在 8 10%以下, 混合、 粉碎过 120目筛即为产品。 检测: 醇提取物(三萜类 物质) 含量为 7%左右; 水提取物 (多糖类物质等) 含量为 12%左右。 Ganoderma lucidum 15 g, Cordyceps 20 g, octagonal 0. 5 g, dried at a low temperature of 60 ° to make the water content below 8 10%, mixed and pulverized through a 120 mesh sieve. Detection: The content of alcohol extract (triterpenoid) is about 7%; the content of water extract (polysaccharide) is about 12%.
^层发酵的灵芝菌丝体 15克, 深层发酵的虫草菌丝体 20克, 八角 1 克, 在 60度下低温干燥使其含水率在 5%以下, 混合、 粉碎过 120目筛即为 产品。 检测: 醇提取物(三萜类物质)含量为 12%左右; 水提取物 (多糖类 物质等) 含量为 21%左右。
上述 4个实施例分别采用现有技术检测: 提取物主要含有生理活性的 三萜类、 多糖类物质; 此外还可以含有核苷、 呋喃、 甾醇、 生物碱、 蛋白 质、 氨基酸等有生理活性的少量化合物、 茴香脑、 微量元素等。 其碴子主 要为植物纤维素、 半纤维素、 木素等。 ^ 15 g of Ganoderma lucidum mycelium fermented in layer, 20 g of deep-fermented Cordyceps mycelium, 1 g of octagonal, dried at a low temperature of 60 ° to make the water content below 5%, mixed and pulverized through a 120 mesh sieve. . Detection: The content of alcohol extract (triterpenoid) is about 12%; the content of water extract (polysaccharide) is about 21%. The above four examples are respectively detected by the prior art: the extract mainly contains physiologically active triterpenoids and polysaccharides; and may also contain physiologically active nucleosides, furans, sterols, alkaloids, proteins, amino acids and the like. A small amount of compound, anethole, trace elements, etc. Its scorpion is mainly plant cellulose, hemicellulose, lignin and the like.
实施例 5 Example 5
按配比优选为: 灵芝 15份, 虫草 20份, 八角 0. 5份, 杜仲叶 5份、 份、 松针粉 5份、 何首乌 1一 2份、 生地 1一 2份、 人参 1份; 在 60度下低 温干燥使其含水率在 8- 12%以下, 混合、 粉碎过 120目筛即为产品。 检测: 醇提取物含量为 22%左右 (其中三萜类占 83%;茴香脑占 5%,绿原酸占 12%); 水提取物 (多糖类物质等) 含量为 28%左右。 According to the ratio, it is preferably: 15 parts of Ganoderma lucidum, 20 parts of Cordyceps, 0.5 parts of octagonal, 5 parts of Eucommia ulmoides, 5 parts of pine needle powder, 1 2 parts of Polygonum multiflorum, 1 2 parts of raw land, 1 part of ginseng; It is dried at a low temperature to have a water content of 8 to 12% or less. The product is mixed and pulverized through a 120 mesh sieve. Detection: The alcohol extract content is about 22% (including triterpenoids accounting for 83%; fennel brain accounting for 5%, chlorogenic acid accounting for 12%); water extract (polysaccharide substances, etc.) content is about 28%.
实施例 6 Example 6
按配比优选为: 灵芝 5份, 虫草 5份, 八角 0. 5份, 杜仲叶 1份、 份、 松针粉 5份、 何首乌 2份、 生地 2份、 人参 20份; 在 60度下低温干燥使 其含水率在 8- 12%以下, 混合、 粉碎过 120目筛即为产品。 检测: 醇提取物 含量为 0. 3%左右(其中三萜类占 82%; 茴香脑占 7%, 绿原酸占 11%) ; 水提 取物 (多糖类物质等) 含量为 0. 5%左右。 The ratio is preferably: 5 parts of Ganoderma lucidum, 5 parts of Cordyceps, 0.5 parts of octagonal, 1 part of Eucommia ulmoides, 5 parts of pine needle powder, 2 parts of Polygonum multiflorum, 2 parts of raw land, 20 parts of ginseng; The water content is below 8-12%, and the product is mixed and pulverized through a 120 mesh sieve. The content of the extract of the water extract (polysaccharide, etc.) is 0.5%; the content of the water extract (polysaccharide, etc.) is 0.5. %about.
实施例 7 Example 7
按配比优选为: 灵芝培养物 15份, 深层发酵的虫草菌丝体 20份, 八 角 1份, 杜仲叶 5份、 份、 松针粉 1份、 何首乌 1一 2份、 生地 1一 2份、 人参 15份; 在 60度下低温干燥使其含水率在 8 - 12%以下, 混合、 粉碎过 120目筛即为产品。检测: 醇提取物含量为 27%左右 (其中三萜类占 85%; 茴 香脑占 5%, 绿原酸占 10%) ; 水提取物 (多糖类物质等) 含量为 35%左右。 According to the ratio, it is preferably: 15 parts of Ganoderma lucidum culture, 20 parts of deep-fermented Cordyceps mycelium, 1 part of octagonal, 5 parts of Eucommia ulmoides, 1 part of pine needle powder, 1 2 parts of Polygonum multiflorum, 1 2 parts of raw land, ginseng 15 parts; low temperature drying at 60 degrees to make the water content below 8 - 12%, mixed and pulverized through a 120 mesh sieve to be the product. Detection: The content of alcohol extract is about 27% (including triterpenoids accounted for 85%; aniseed brain accounted for 5%, chlorogenic acid accounted for 10%); water extracts (polysaccharides, etc.) content was about 35%.
实施例 8 Example 8
按配比优选为: 杨树叶或树枝 20份, 猴头菌 (菇) 20份, 八角 0. 5份, 金银花 5份、 份、松针粉 1份、 何首乌 1一 2份、 生地 1一 2份、人参 20份; 在 60度下低温千燥使其含水率在 8- 12%以下, 混合、 粉碎过 120目筛即为 产品。 检测: 醇提取物含量为 0. 3%左右 (其中三萜类占 80%; 茴香脑占 4%, 绿原酸占 16%) ; 水提取物 (多糖类物质) 含量为 0. 5%左右。 要原料组份: 灵芝或其培养物或杨树叶、 冬虫草或其培养物、 杜仲
叶或金银花、 八角粉、 松针粉分别在 60- -70°C下千燥至含水量在 8-- 12%范 围, 经分别粉碎后, 按配方 (以绝干重量计), 灵芝或其灵芝培养物或杨树 叶 15份、 冬虫草或其冬虫草培养物 20份、 杜仲叶或金银花 5份、八角粉 1 份、 松针粉 1份、 何首乌 2份、 生地 1份、 人参 5份混合均匀, 即为成品。 According to the ratio, it is preferably: 20 leaves of poplar leaves or branches, 20 parts of Hericium erinaceus (mushroom), 0 parts of octagonal, 5 parts of honeysuckle, 1 part, 1 part of pine needle powder, 1 2 parts of Polygonum multiflorum, 1 2 parts of raw land, 20 parts of ginseng; dried at a low temperature of 60 degrees to make the water content below 8-12%, mixed and pulverized through a 120 mesh sieve. 5%。 The content of the alcohol extract is about 0.3% (including triterpenoids accounted for 80%; fennel brain accounted for 4%, chlorogenic acid accounted for 16%); water extract (polysaccharide) content of 0. 5% about. Raw material components: Ganoderma lucidum or its culture or poplar leaves, Cordyceps or its culture, Eucommia Leaves or honeysuckle, octagonal powder, pine needle powder are dried at 60--70 ° C to a water content of 8 - 12%, after crushing separately, according to the formula (based on absolute dry weight), Ganoderma Lucidum or its Ganoderma Lucidum 15 parts of culture or poplar leaves, 20 parts of Cordyceps or its Cordyceps culture, 5 parts of Eucommia ulmoides or honeysuckle, 1 part of octagonal powder, 1 part of pine needle powder, 2 parts of Polygonum multiflorum, 1 part of raw land, 5 parts of ginseng, evenly mixed, It is the finished product.
实施例 10 Example 10
主要原料组份: 灵芝或其培养物或杨树叶、 冬虫草或其培养物、 杜仲 叶或金银花、 八角粉、 松针粉分别在 60- -70°C下干燥至含水量在 8— 12%范 围, 经分别粉碎后, 按配方 (以绝干重量计), 灵芝或其灵芝培养物或杨树 叶 5份、冬虫草或其冬虫草培养物 5份、 杜仲叶或金银花 3份、 八角粉 0. 8 份、 松针粉 3份、 何首乌 2份、 生地 2份、 人参 10份混合均匀, 即为成品。 Main raw material components: Ganoderma lucidum or its culture or poplar leaves, Cordyceps or its culture, Eucommia ulmoides or honeysuckle, octagonal powder, pine needle powder are dried at 60--70 ° C to a water content of 8-12% After crushing separately, according to the formula (based on the absolute dry weight), Ganoderma lucidum or its Ganoderma lucidum culture or poplar leaves 5 parts, Cordyceps or its Cordyceps culture 5 parts, Eucommia or honeysuckle 3 parts, octagonal powder 0. 8 parts, 3 parts of pine needle powder, 2 parts of Polygonum multiflorum, 2 parts of raw land, and 10 parts of ginseng are evenly mixed, which is the finished product.
实施例 11 Example 11
主要原料组份: 灵芝或其培养物或杨树叶、 冬虫草或其培养物、 杜仲 叶或金银花、 八角粉、 松针粉分别在 60- -7CTC下千燥至含水量在 8- -12%范 围, 经分别粉碎后, 按配方 (以绝干重量计), 灵芝或其灵芝培养物或杨树 叶 10份、 冬虫草或其冬虫草培养物 5份、 杜仲叶或金银花 5份、 八角粉 1 份、松针粉 5份、 何首乌 2份、 生地 2份、 人参 20份混合均匀, 即为成品。 Main raw material components: Ganoderma lucidum or its culture or poplar leaves, Cordyceps sinensis or its culture, Eucommia ulmoides or honeysuckle, octagonal powder, pine needle powder, respectively, dried at 60--7 CTC to a water content of 8--12% After crushing separately, according to the formula (based on the dry weight), Ganoderma lucidum or its Ganoderma lucidum culture or 10 leaves of poplar, 5 pieces of Cordyceps or its Cordyceps culture, 5 parts of Eucommia or Honeysuckle, 1 part of octagonal powder 5 parts of pine needle powder, 2 parts of Polygonum multiflorum, 2 parts of raw land, 20 parts of ginseng are evenly mixed, which is the finished product.
实施例 12 Example 12
主要原料组份: 灵芝或其培养物或杨树叶、 冬虫草或其培养物、 杜仲 叶或金银花、 八角粉、 松针粉分别在 60-- 70°C下千燥至含水量在 8— 12%范 围, 经分别 fHi卒后, 按配方 (以绝干重量计), 灵芝或其灵芝培养物或杨树 叶 15份、冬虫草或其冬虫草培养物 5份、杜仲叶或金银花 5份、八角粉 0. 5 份、 松针粉 5份、 何首乌 1份、 生地 1份、 人参 1份混合均匀, 即为成品。 Main raw material components: Ganoderma lucidum or its culture or poplar leaves, Cordyceps sinensis or its culture, Eucommia ulmoides or honeysuckle, octagonal powder, pine needle powder are dried at 60--70 ° C to water content of 8-12% Scope, after fHi stroke, according to formula (based on absolute dry weight), Ganoderma lucidum or its Ganoderma lucidum culture or 15 leaves of poplar, 5 pieces of Cordyceps or its Cordyceps culture, 5 parts of Eucommia ulmoides or honeysuckle, octagonal powder 0. 5 parts, 5 parts of pine needle powder, 1 part of Polygonum multiflorum, 1 part of raw land, 1 part of ginseng is evenly mixed, which is the finished product.
实施例 13 Example 13
主要原料组份: 灵芝或其培养物或杨树叶、 冬虫草或其培养物、 杜仲 叶或金银花、 八角粉、 松针粉分别在 60--7CTC下干燥至含水量在 8- - 12%范 围, 经分别-粉碎后, 按配方 (以绝干重量计), 灵芝或其灵芝培养物或杨树 叶 15份、冬虫草或其冬虫草培养物 5份、 杜仲叶或金银花 5份、 八角^分01 份、松针粉 5份、 何首乌 2份、 生地 2份、 人参 20份混合均匀, 即为成品。 Main raw material components: Ganoderma lucidum or its culture or poplar leaves, Cordyceps or its culture, Eucommia ulmoides or honeysuckle, octagonal powder, pine needle powder are dried at 60--7 CTC to a water content of 8 - 12%, After separately-pulverized, according to the formula (based on the absolute dry weight), Ganoderma lucidum or its Ganoderma lucidum culture or 15 leaves of poplar, 5 pieces of Cordyceps or its Cordyceps culture, 5 parts of Eucommia ulmoides or honeysuckle, octagonal ^ 01 5 parts of pine needle powder, 2 parts of Polygonum multiflorum, 2 parts of raw land, 20 parts of ginseng are evenly mixed, which is the finished product.
上述 5-13的 9个实施例分别采用现有技术检测: 其醇提取物含量重量 在 0. 3—- 27%范围, 用水在 PH 7- 9的条件下提取, 其水提取物含量重量在
0. 5 --- 35%范围; 提取物主要含有萜类、 多糖类、 茴香脑、 绿原酸、 派烯、 槲皮素、 大黄素、 大黄素甲醚; 结合蒽醌类、 环烯醚萜甙类等化合物, 此 外还含有核苷、 呋喃、 甾醇、 β -谷甾醇 谷 醇、 龙脑、 生物碱、 蛋白质、 生物多肽、 氨基酸、 黄酮、 京尼平苷、 京尼平苷酸等环烯醚类、 甘露醇、 磷脂、 对丙烯基苯酚异戊烯醚、 微量元素等。 其碴子主要为植物纤维素、 半纤维素、 木素等。 The above nine embodiments of 5-13 are respectively detected by the prior art: the alcohol extract content is in the range of 0.3 to 27%, and the water is extracted under the condition of pH 7-9, and the water extract content is 0. 5 --- 35% range; extract mainly contains terpenoids, polysaccharides, anethole, chlorogenic acid, propene, quercetin, emodin, emodin methyl ether; combined anthraquinones, cycloolefins Compounds such as ether steroids, in addition to nucleosides, furans, sterols, β-sitosterol, borneol, alkaloids, proteins, biological peptides, amino acids, flavonoids, genipin, genipin, etc. Cycloolefins, mannitol, phospholipids, p-propenyl phenol isopentenes, trace elements, and the like. Its scorpion is mainly plant cellulose, hemicellulose, lignin and the like.
实施例 14 Example 14
实施例 1-13的添加剂分别用于鹿饲料试验: The additives of Examples 1-13 were used for the deer feed test, respectively:
对照组是在与试验组同等条件下, 不加添加剂。 试验效果: The control group was under the same conditions as the test group without additives. Test effect:
1、 喂养仔鹿: 取二组, 每组 80只仔鹿, 试验一年称重对比, 试验组 比对照组平均每只增重 10%。 1. Feeding the deer: Take two groups of 80 deer in each group, and compare the weighing in one year. The experimental group gained 10% more than the control group.
2、 喂养育成鹿: 取二组, 每组 60只育成鹿, 试验一年统计对比, 试 验组比对照组的发病率低 15%。 且产茸期提前 5-10天。、 2. Feeding and breeding deer: Take two groups, each group of 60 brooding broods, one year statistical comparison, the test group was 15% lower than the control group. And the velvet period is 5-10 days in advance. ,
3、 喂养产茸期鹿: 取二组, 每组 60只育成鹿, 一个产茸期统计对比, 试验组比对照组产茸量高 10%。 3. Feeding the velvet period deer: Take two groups, each group of 60 bred deer, a statistical comparison of the antler production period, the test group is 10% higher than the control group.
4、 喂养配种鹿: 取二组, 每组 60只育成鹿, 其中公鹿 6只, 母鹿 54 只, 试验一年统计对比, 试验组比对照组受孕产仔率高 5-10%。 实施例 15 4. Feeding breeding deer: Take two groups, each group of 60 brooding deer, including 6 male deer and 54 female deer. The experimental group has a statistical comparison of one year, and the experimental group has a higher rate of 5-10% than the control group. Example 15
实施例 1-13的添加剂分别用于奶牛饲料试验: 对照组是在与试验组同 等条件下, 不加添加剂。 试验效果-.
试验组 添加剂量 饲料组分 奶增产量 粒状玉米 25kg, 片状豆粕 2. 5kg, The additives of Examples 1-13 were used for the cow feed test, respectively: The control group was under the same conditions as the test group without additives. Test effect -. 5公斤,,,,,,,,,,,,,,,,,,,,,,,,,,,,
1 100 g 10% 糠麸 5kg 1 100 g 10% bran 5kg
粒状玉米 25kg, 片状豆粕 2. 5kg, Granulated corn 25kg, flaky soybean meal 2. 5kg,
2 300 g 15% 糖麸 5kg 2 300 g 15% sugar bran 5kg
粒状玉米 25kg, 片状豆粕 2. 5kg, Granulated corn 25kg, flaky soybean meal 2. 5kg,
3 250 g 15% 糖麸 5kg 3 250 g 15% sugar bran 5kg
粒状玉米 25kg, 片状豆粕 2. 5kg, Granulated corn 25kg, flaky soybean meal 2. 5kg,
4 150 g 13% 糖麸 5kg 实施例 16 4 150 g 13% sugar bran 5kg Example 16
采用全价饲料加入 2%本发明实施例 4-6的三个的添加剂进行小鸡、 小 鸭的饲养试验情况见下表: The feeding test of chickens and ducklings using the full-price feed of 2% of the three additives of Examples 4-6 of the present invention is shown in the following table:
小鸭词养 30天的情况: ( kg) The duckling word for 30 days: (kg)
分别取实施例 1-13的添加剂 20克加入到 1000克精饲料中。精词料包 括玉米粉、 麦皮、 豆粕。 喂养对象为仔鹿、 产茸期鹿、 泌乳期母鹿。 20 g of the additives of Examples 1-13 were separately added to 1000 g of the concentrate. The vocabulary includes corn flour, wheat husk and soybean meal. The feeding objects are the deer, the velvet deer, and the lactating female deer.
实施例 18
分别取实施例 1-13的添加剂 20克、 磷酸氢钙 4克、 鱼骨粉 11克, 加 入到 1000克精词料中。喂养对象为发情期公鹿、发情期母鹿和临产期母鹿。 Example 18 20 g of the additives of Examples 1-13, 4 g of calcium hydrogen phosphate, and 11 g of fish bone meal were respectively taken and added to 1000 g of the sperm. The feeding targets are erotic male deer, estrus female deer and maternity doe.
实施例 19 Example 19
分别取实施例 5- 13的添加剂 20克、 磷酸氢钙 3克、 鱼骨粉 18克, 加入到 1000克精饲料中。 喂养对象为发情期产茸鹿及越冬母鹿。 20 g of the additives of Examples 5-13, 3 g of calcium hydrogen phosphate, and 18 g of fish bone meal were respectively added to 1000 g of the concentrate. The feeding objects are erotic antlers and wintering female deer.
实施例 17、 18、 19喂养试验效果对比: Example 17, 18, 19 feeding test comparison:
本词料添加剂中各种物质均以粉末状态存在。 属营养型词料添加剂。 它们的作用分别为 Various substances in the term additive are present in a powder state. It is a nutritional word additive. Their role is
虫草及其培养物的作用是健脾益肺、 养血生精、 增产鹿茸, 且提高动 物免疫功能从而起到防病治病之功效。 The role of Cordyceps and its culture is to strengthen the spleen and improve the lungs, nourish the blood and produce sperm, increase the production of antler, and improve the immune function of the animal to prevent and treat diseases.
灵芝及其培养物的作用是养肝、 健胃、 补肾、 明目, 且提高动物免疫 功能从而起到解毒及防病治病之功效。 The role of Ganoderma lucidum and its culture is to nourish the liver, strengthen the stomach, tonify the kidney, improve the eyesight, and improve the immune function of the animal to play the role of detoxification and disease prevention and treatment.
杜仲叶中含杜仲胶、 多糖、 黄酮、 松脂醇二葡萄糖苷、 桃叶珊瑚苷、 京尼平苷、 苯丙素类化合物绿原酸、 槲皮素、 山柰醇、 及其环烯醚萜类和 木脂素类等次生代谢产物, 丁香脂素二糖甙 (SGD),京尼平甙酸 (GA)化合物 等多种活性化学成分, 含有 17种氨基酸和 20多种微量元素, 营养十分丰 富; 具有补肝肾、 强筋骨、 安胎的功效。 Eucommia ulmoides contains eucommia gum, polysaccharides, flavonoids, rosinol diglucoside, azurin, genipin, phenylpropanoid chlorogenic acid, quercetin, behenyl alcohol, and its iridoids Secondary active metabolites such as lignans, sucrose disaccharide (SGD), genipin citrate (GA) compounds and other active chemical constituents, containing 17 amino acids and more than 20 trace elements, nutrition Very rich; with the effect of liver and kidney, strong bones, and fetus.
松针粉含粗蛋白质 12. 96%, 粗脂肪 11. 1%, 粗纤维 27. 1%, 无氮浸出物 41. 5%, 灰分 3. 43%、 维生素 A含量为 950〜2203my/kg, 还含有丰富的维生 素 (:、 维生素 E和硒元素。 维生素 A、 维生素 E、 维生素 C都与机体的免疫 力。 Pine needle powder containing crude protein 12.96%, crude fat 11.1%, crude fiber 27.1%, nitrogen-free extract 41. 5%, ash 3. 43%, vitamin A content 950~2203my/kg, also It is rich in vitamins (:, vitamin E and selenium. Vitamin A, vitamin E, and vitamin C are all immune to the body.
八角: 其含有复杂的芳香油, 其反式大茴香脑, α—蒎烯、 柠檬烯、 芳樟醇、 4一萜品醇、 草蒿脑、 茴香醛等成分具有理气开巧之功效, 起到催 化剂的作用。 ; Star anise: It contains complex aromatic oil, its trans-anisal brain, α-pinene, limonene, linalool, 4-terpineol, artemisia, anisaldehyde and other ingredients have the effect of dexterity, play The role of the catalyst. ;
何首乌: 含大黄素、 大黄酚、 大黄素甲醚等蒽醌类、 乙酰苯甙等化合 物和白藜芦醇、 云杉新甙等, 还含没食子酸、 右旋儿茶精、 右旋表儿茶精 等化合物。 具有养血滋阴, 润肠通便, 截疟, 祛风, 解毒。 Polygonum multiflorum: steroids such as emodin, chrysophanol, emodin methyl ether, acetophenone and other compounds, resveratrol, spruce, etc., also contains gallic acid, dextrorotatory tea, right-handed Compounds such as tea essence. It has nourishing blood, nourishing yin, laxative, malaria, hurricane, detoxification.
生地: 清热、 生津、 凉血; 生地黄: 清热、 生津、 润燥、 滑肠、 破瘀、 生新、 止痛、 调经、 金疮瘀、 凉血、 止血; 熟地黄: 滋阴补肾、 调经补血、 血虚头痛、 肝痛。
以上饲料添加剂用作鹿词料添加剂, 可使仔鹿生长快, 茸鹿产茸量提 高, 母鹿怀胎率提高, 茸鹿膘情持久, 抗病能力强, 的作用, 其肉质滑嫩, 口感鲜美, 营养丰富, 没有药物残留污染。 经试验对比, 其综合作用和效 果为: Place of birth: heat, Shengjin, cool blood; Rehmannia: heat, Shengjin, Runzao, slippery, broken phlegm, new, analgesic, menstruation, golden sore, cool blood, stop bleeding; Rehmannia glutinosa: nourishing yin and tonifying kidney, regulating menstruation, Blood deficiency headache, liver pain. The above feed additive is used as a deer material additive, which can make the deer grow fast, the velvet antler has increased germination, the female deer has a higher pregnancy rate, the stag deer has a long-lasting feeling, and the disease resistance is strong, and the meat is smooth and tender, and the taste is delicious. It is nutritious and has no drug residue contamination. Through experimental comparison, its comprehensive effects and effects are:
A、 仔鹿生长速度快, 增重率约 11%; A. The growth rate of the deer is fast, and the weight gain rate is about 11%;
B、 鹿茸产量提高约 13%; B. The production of antler is increased by about 13%;
C、 母鹿怀胎率提高约 8%; C, the mother's pregnancy rate increased by about 8%;
D、 抗病能力提高约 10%; D, the disease resistance increased by about 10%;
E、 梅花鹿的毛色更艳亮; E, the color of the sika deer is more bright;
F、 提高了鹿茸、 鹿肉产品的品质, 以麂茸为例, 活性钙及 SOD (超氧 化物歧化敏)、 硒的含量有所提高, 可以帮助人体抗衰老, 延年益寿。 四叉 新鲜茸中 SOD 活性含量为 40U/g, 活性钙为 7. 5 X 10 mg/100g , 硒为 0. l lmg/kg。 F. Improve the quality of antler and venison products. Taking velvet antler as an example, the content of active calcium and SOD (superoxide dismutation) and selenium is improved, which can help the body to resist aging and prolong life. The active content of SOD in fresh velvet is 40 U/g, the active calcium is 7. 5 X 10 mg/100 g, and the selenium is 0.1 lmg/kg.
鱼骨粉的作用是补充、 提高饲料中的含磷量、 钙量及蛋白质含量, 以 此来满足动物生长的需要, 尤其是仔鹿的生长发育和茸鹿产茸期的需求。 The role of fish bone meal is to supplement and increase the phosphorus content, calcium content and protein content in the feed, so as to meet the needs of animal growth, especially the growth and development of the deer and the velvet period of the deer.
磷酸氢钙主要是为了满足仔鹿快速生长及茸鹿产茸期对磷、 钙元素需 求。 Calcium hydrogen phosphate is mainly used to meet the needs of phosphorus and calcium in the rapid growth of the deer and the velvet period of the deer.
本词料添加剂的综合作用为: 养血生精, 增加动物生殖细胞的活动能 力, 提高受孕产仔率。 养肝益脾, 健胃补肾, 提高反刍动物的消化功能, 促进仔鹿生长, 育成鹿保膘。 清火解毒, 增强免疫抗病能力。 增加钙、 磷 元素, 促进骨骼生长, 提高鹿茸产量。 The comprehensive function of the term additive is: nourishing blood and sperm, increasing the activity capacity of animal germ cells, and increasing the rate of conception. Live the liver and benefit the spleen, strengthen the stomach and tonify the kidney, improve the digestive function of the ruminant, promote the growth of the deer, and develop the deer. Clear fire and detoxification, enhance immunity and disease resistance. Increase calcium and phosphorus, promote bone growth, and increase antler yield.
―、 喂养仔鹿: ―, feeding the deer:
取二组, 每组 45只仔鹿, A组按实施例一方案喂养, B组喂未加饲料 添加剂的普通词料, 试验一年称重对比, A组比 B组平均每只增重 11%。 Take two groups, each group of 45 deer, group A is fed according to the first embodiment, group B is fed with the common word of no feed additive, and the test is compared with one year. The average weight of group A is 11% higher than that of group B. .
二、 喂养产茸期鹿: Second, feeding the velvet period deer:
取二组, 每组 45只仔鹿, C组按实施例一方案喂养, D组喂未加本饲 料添加剂的普通饲料, 一个产茸期对比, C组的产量比 D组高 13%。 Take two groups, each group of 45 deer, group C is fed according to the first embodiment, group D is fed with ordinary feed without added feed additive, and the yield of group C is 13% higher than that of group D.
三、 喂养配种鹿 Third, feeding breeding deer
取二组, 每组 45只育成鹿, 其中公鹿 5只, 母鹿 40只, E组平时按实 施例一方案喂养, 到发情配种期时改按实施二方案喂养, F组一直喂养普通
未加本词料添加剂的饲料, 试验一年, 统计对比二组的受孕产仔率, E组比 F组高 8%。 Take two groups, each group of 45 bred deer, including 5 male deer and 40 female deer. Group E is usually fed according to the first embodiment. When the estrus breeding period is changed, it is fed according to the implementation scheme. The feed without the additive of the term material was tested for one year, and the fertility rate of the two groups was statistically compared. The E group was 8% higher than the F group.
四、 对比组 Fourth, the comparison group
取二组, 每组 45只母鹿, G组用本饲料添加剂然养, 不同时期用上述 不同的实施例组份喂养, H组白未加本词料添加剂的各通饲料然养, 试验一 年, 技合效果对比, 两组的抗病能力, G组比 H组的抗病能力提高了 10%。 Take two groups, each group of 45 female deer, group G is supplemented with this feed additive, and fed with different embodiments of the above-mentioned different components in different periods, and the H group is not added with the additives of the word additive, test one In the year, the TC effect was compared, and the disease resistance of the two groups was improved by 10% compared with the H group.
所述灵芝及其培养物是用稻壳作培养基, 培养基经加压包装后钻孔, 拌上灵芝菌种, 在一定的温度、 湿度和光照下培养出灵芝培养物。 The ganoderma lucidum and the culture thereof are prepared by using rice husk as a culture medium, and the culture medium is bored by pressure packaging, and the Ganoderma lucidum strain is mixed, and the Ganoderma lucidum culture is cultured under a certain temperature, humidity and illumination.
所述虫草及其培养物是用蜂皇蛹为主料作培养基。 将虫草菌种放入培 养基中, 再一起放入玻璃容皿中, 在一定的温度、 R度、 光照下培养出。
The Cordyceps and its culture are mainly used as a medium for the royal jelly. The Cordyceps species are placed in a medium, placed in a glass container, and cultured at a certain temperature, R degree, and illumination.
Claims
1、 一种绿色环保畜禽饲料添加剂, 包括非有效的成分, 水、 醇不溶物 和有效的成分, 水、 醇提取物两部分, 其特征在于: 水、 醇不溶物主要为 植物纤维素、 半纤维素、 木素, 水、 醇提取物主要包括萜类、 多糖类、 茴 香脑、 绿原酸、 派烯、 槲皮素、 大黄素、 大黄素甲醚、 结合蒽醌类, 环烯 醚萜甙类化合物构成, 其醇提取物含量重量在 0. 3- --27%范围, 用水在 PH 7-9的条件下提取, 其水提取物含量重量在 0. 5 --- 35%范围。 1. A green and environmentally-friendly livestock and poultry feed additive, comprising non-effective ingredients, water, alcohol-insoluble matter and effective ingredients, water and alcohol extract, characterized in that: water, alcohol-insoluble matter is mainly plant cellulose, Hemicellulose, lignin, water, alcohol extracts mainly include terpenoids, polysaccharides, anethole, chlorogenic acid, propene, quercetin, emodin, emodin, ethers, cyclic olefins 5 -- 35%, the weight of the water extract is 0. 5 --- 35%, the weight of the water extract is 0. 5 --- 35% range.
2、 根据权力要求 1所述的绿色环保畜禽词料添加剂, 其特征在于: 其 醇提取物含量重量优选在 1. 3 --- 15%范围, 其水提取物含量重量优选在 1. 5—21%范围。 2 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 - 21% range.
3、 根据权力要求 1.所述的绿色环保畜禽饲料添加剂, 其水、 醇提取物 中的主要化合物, 各占水、 醇提取物总量的比例, 以重量计, 多糖类在 15- -45%范围,萜类在 12- -41%范围,茴香脑在 1- - 2%范围,绿原酸在 1. 5—5% 范围, 派烯在 0. 1- -3%范围, 槲皮素、 大黄素、 大黄素甲醚、 结合蒽醌类在 0. 5- -2%范围,环烯醚萜甙类化合物 0. 5— 2%范围。 3. The green environmentally-friendly livestock and poultry feed additive according to claim 1. The main compounds in water and alcohol extracts, each of which accounts for the total amount of water and alcohol extracts, by weight, the polysaccharides are in 15- In the range of -45%, the terpenoid is in the range of 12-41%, the fennel is in the range of 1-2%, the chlorogenic acid is in the range of 1.5-5%, and the ene is in the range of 0.1-3%, 槲5至范围内。 The dermatin, emodin, emodin, conjugated steroids in the range of 0. 5- -2%, iridoids oxime compound 0. 5-2% range.
4、 根据权力要求 1所述的绿色环保畜禽词料添加剂, 其水、 醇提取物 中的多糖类, 萜类, 茴香脑, 绿原酸, 派烯, 槲皮素、 大黄素、 大黄素甲 醚、 结合蔥醌类, 环烯醚萜甙类化合物特征在于: 4. The environmentally friendly livestock and poultry word additive according to claim 1, wherein the water, the polysaccharide in the alcohol extract, the steroid, the fennel, the chlorogenic acid, the phenylene, the quercetin, the emodin, the rhubarb Methyl ether, combined with onion, and iridoids are characterized by:
A、 其萜类主要为五环三萜、 四环三萜化合物, 其五环三萜、 四环三萜 中, 主要是灵芝三萜和人参皂苷, 其中有不少于 60%的为灵芝三萜, 其灵芝 三萜中不少于 10%的三萜为下述基本结构:
A. Its anthraquinones are mainly pentacyclic triterpene and tetracyclic triterpene compounds. Among the five-ring triterpenes and tetracyclic triterpenes, mainly Ganoderma lucidum triterpenoids and ginsenosides, of which not less than 60% are Ganoderma lucidum III.萜, not less than 10% of the three mites in the Ganoderma lucidum are the following basic structures:
结构中的 Rl, R2, R3分别是 1一 4碳的烯基、 烷基、 羟基、 羧基、 酮 基、 醛基、 醚基之一的功能团, 其中 C8-C9, C11-C12, C16- 17, C20-22, C23-2 为双键结构的三萜, 其占总萜的 1一6%范围, R1, R2, and R3 in the structure are each a functional group of one to four carbon alkenyl groups, an alkyl group, a hydroxyl group, a carboxyl group, a ketone group, an aldehyde group, and an ether group, wherein C8-C9, C11-C12, C16- 17, C20-22, C23-2 is a triple bond structure, which accounts for 1-6% of the total enthalpy.
B、 萜类中含有不少于 10%的人参皂苷, B. The mites contain not less than 10% ginsenosides.
C、 其提取物中含有不少于 1%的绿原酸, 其主要基本化学结构为- C. The extract contains not less than 1% chlorogenic acid, and its main basic chemical structure is -
D、 茴香脑中, 其反式茴香脑不少于 75%, D, the fennel brain, its trans-fennel brain is not less than 75%,
E、 派'烯中, 其 α 派烯不少于 75%, E, in the 'ene, its α-pyrene is not less than 75%,
F、 大黄素、 大黄素甲醚、 结合蒽醌类成分主要由大黄素- 8-0- β -D-葡萄糖 苷、 大黄酚 -8 0- β - D-葡萄糖苷、 大黄素甲醚- 8-0- β -D-葡萄糖苷组成, F, emodin, emodin methyl ether, combined terpenoids are mainly composed of emodin - 8-0-β-D-glucoside, chrysophanol-8 0-β-D-glucoside, emodin methyl ether-8 -0- β -D-glucoside composition,
G、二苯乙烯苷类成分主要为 2, 3, 5, 4' -四羟基二苯乙烯- 2-0- β D-葡萄糖 苷, 含量占 90%以上, G, the stilbene glycoside is mainly 2, 3, 5, 4'-tetrahydroxystilbene-2-0-β D-glucoside, the content accounts for more than 90%.
Η、 环烯醚萜甙类化合物, 其主要活性成分为梓醇、 甘露醇、 β -谷甾醇, I、 多糖类主要包括葡聚糖、 杂多糖和肽多糖的多糖, 其分子量在 3000— 500000之间。
5、 一种绿色环保畜禽词料添加剂配方, 其特征在于: 以绝干重量计, 其主要由灵芝或其灵芝培养物或杨树叶 5- -15克, 虫草或其虫草培养物或 猴头菌 5— 20克、 八角 0. Η, iridoids, the main active ingredients are decyl alcohol, mannitol, β-sitosterol, I, polysaccharides mainly include polysaccharides of dextran, heteropolysaccharides and peptide polysaccharides, the molecular weight of which is 3000- Between 500000. 5. A green environmental protection animal and animal word additive formulation, characterized in that: based on the absolute dry weight, it is mainly composed of Ganoderma lucidum or its Ganoderma lucidum culture or poplar leaves 5 - 15 g, Cordyceps or its Cordyceps culture or monkey head Bacteria 5-20 grams, octagonal 0.
5-1克范围的比例配合。 A ratio of 5-1 gram range fits.
6、根据权力要求 5所述的绿色环保畜禽词料添加剂配方,其特征在于: 以绝干重量计, 其优选主要由灵芝或其灵芝培养物或杨树叶 5— 15 份、 虫 草或其虫草培养物 1—5份、 八角 0. 5—1份、 杜仲叶或金银花 1一 5份、 松 针粉 1一 5份、 何首乌 1一 2份、 生地 1一 2份、 人参 1一 20份构成。 6. The green environmentally-friendly livestock word additive formulation according to claim 5, characterized in that it is preferably mainly composed of Ganoderma lucidum or its Ganoderma lucidum culture or 5-15 parts of poplar leaves, Cordyceps or Cordyceps. 1 to 5 parts of culture, 8.5 to 1 part of octagonal, 1 to 5 parts of Eucommia ulmoides or honeysuckle, 1 to 5 parts of pine needle powder, 1 to 2 parts of Polygonum multiflorum, 1 to 2 parts of raw land, and 1 to 20 parts of ginseng.
7、 一种绿色环保鹿饲料添加剂制备方法, 其特征在于: 原料灵芝或其 培养物或杨树叶、 冬虫草或其培养物、 杜仲叶或金银花、 八角、 松针、 何 首乌、 生地、 人参分别在 60--70°C下干燥至含水量在 8—12%范围, 经分别 粉碎后, 按配方, 以绝干重量计, 灵芝或其灵芝培养物或杨树叶 5— 15份、 冬虫草或其冬虫草培养物 1一 5份、 杜仲叶或金银花 1一 5份、 八角 0. 5—1 份、松针 1一 5份、何首乌 1—2份、生地 1—2份、人参 1一 20份混合均匀, 即为成品或再进而造粒加工获得颗粒产品。 7. A preparation method of green environmentally friendly deer feed additive, characterized in that: raw material Ganoderma lucidum or its culture or poplar leaf, Cordyceps militaris or its culture, Eucommia ulmoides or honeysuckle, star anise, pine needle, Polygonum, ginseng, ginseng respectively in 60 - Dry at 70 ° C until the water content is in the range of 8-12%, after crushing separately, according to the formula, based on the absolute dry weight, Ganoderma lucidum or its Ganoderma lucidum culture or Yang leaves 5-15 parts, Cordyceps or its winter 1 to 5 parts of Cordyceps culture, 1 to 5 parts of Eucommia ulmoides or honeysuckle, 0.5 to 1 part of octagonal, 1 to 5 parts of pine needles, 1-2 parts of Polygonum multiflorum, 1-2 parts of raw land, and 1 to 20 parts of ginseng , that is, the finished product or the granulation process to obtain the granulated product.
8、 本发明的绿色环保畜禽饲料添加剂, 为鹿饲料添加剂。.
8. The green environmentally-friendly livestock and poultry feed additive of the present invention is a deer feed additive. .
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CN200710027557.4 | 2007-04-13 | ||
CNA2007100275574A CN101040666A (en) | 2007-04-13 | 2007-04-13 | Novel feed additive for deers |
CN2007101036227A CN101053369B (en) | 2007-04-29 | 2007-04-29 | Feed additive for fowls and domestic animals and preparation method thereof |
CN200710103622.7 | 2007-04-29 |
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