WO2005004915A3 - Compositions comprising meloxicam - Google Patents

Compositions comprising meloxicam Download PDF

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Publication number
WO2005004915A3
WO2005004915A3 PCT/EP2004/007264 EP2004007264W WO2005004915A3 WO 2005004915 A3 WO2005004915 A3 WO 2005004915A3 EP 2004007264 W EP2004007264 W EP 2004007264W WO 2005004915 A3 WO2005004915 A3 WO 2005004915A3
Authority
WO
WIPO (PCT)
Prior art keywords
meloxicam
compositions
antacids
sedatives
analgesic
Prior art date
Application number
PCT/EP2004/007264
Other languages
French (fr)
Other versions
WO2005004915A2 (en
Inventor
Minoru Okada
Hiroshi Otaki
Norimitsu Umehara
Akira Takahashi
Toshiaki Horie
Hideyoshi Kanbe
Original Assignee
Boehringer Ingelheim Int
Boehringer Ingelheim Pharma
Minoru Okada
Hiroshi Otaki
Norimitsu Umehara
Akira Takahashi
Toshiaki Horie
Hideyoshi Kanbe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Boehringer Ingelheim Pharma, Minoru Okada, Hiroshi Otaki, Norimitsu Umehara, Akira Takahashi, Toshiaki Horie, Hideyoshi Kanbe filed Critical Boehringer Ingelheim Int
Priority to JP2006518101A priority Critical patent/JP2009513512A/en
Publication of WO2005004915A2 publication Critical patent/WO2005004915A2/en
Publication of WO2005004915A3 publication Critical patent/WO2005004915A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
  • Anesthesiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to a pharmaceutical composition comprising meloxicam or a pharmaceutically acceptable salt thereof, allowing itself to exert anti-inflammatory, analgesic and antipyretic effects, and at least a second pharmaceutically active compound selected from the group consisting of antacids, sedatives and central nervous system stimulants.
PCT/EP2004/007264 2003-07-09 2004-07-03 Compositions comprising meloxicam WO2005004915A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2006518101A JP2009513512A (en) 2003-07-09 2004-07-03 Composition comprising meloxicam

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP03015435 2003-07-09
EP03015436.3 2003-07-09
EP03015436 2003-07-09
EP03015435.5 2003-07-09
EP03015741.6 2003-07-10
EP03015741 2003-07-10

Publications (2)

Publication Number Publication Date
WO2005004915A2 WO2005004915A2 (en) 2005-01-20
WO2005004915A3 true WO2005004915A3 (en) 2005-03-17

Family

ID=34068724

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/007264 WO2005004915A2 (en) 2003-07-09 2004-07-03 Compositions comprising meloxicam

Country Status (2)

Country Link
JP (2) JP2009513512A (en)
WO (1) WO2005004915A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10161077A1 (en) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Highly concentrated stable meloxicam solutions for needleless injection
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
US20080255104A1 (en) * 2004-05-04 2008-10-16 Equitech Corporation Nsaid Compositions
MX2012004177A (en) 2009-10-12 2012-05-08 Boehringer Ingelheim Vetmed Containers for compositions comprising meloxicam.
SG183846A1 (en) 2010-03-03 2012-10-30 Boehringer Ingelheim Vetmed Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
SI2760821T1 (en) * 2011-09-02 2018-02-28 Novartis Ag Choline salt of an anti-inflammatory substituted cyclobutenedione compound
JP6226278B2 (en) * 2012-08-03 2017-11-08 国立大学法人愛媛大学 Immune cell activation inhibitor and use thereof
AU2013403623A1 (en) * 2013-10-22 2016-06-09 Edward Tak Wei 1-di(sec-butyl)-phosphinoyl-pentane (DAPA-2-5) as a topical agent for the treatment of discomfort from non-keratinized stratified epithelial (NKSE) tissue
US9526734B2 (en) * 2014-06-09 2016-12-27 Iceutica Pty Ltd. Formulation of meloxicam
JP7209537B2 (en) * 2018-02-23 2023-01-20 ライオン株式会社 Solid pharmaceutical formulation
JP7348703B2 (en) 2019-06-28 2023-09-21 エスエス製薬株式会社 Meloxicam-containing granules
JP7391639B2 (en) * 2019-12-06 2023-12-05 ライオン株式会社 pharmaceutical formulations

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3434707A1 (en) * 1983-10-07 1985-04-18 Laboratorio Italiano Biochimico e Farmaceutico LISAPHARMA S.p.A., Erba, Como Non-ulcerogenic pharmaceutical compositions having anti-inflammatory and/or analgesic activity
EP0465235A1 (en) * 1990-07-03 1992-01-08 McNEIL-PPC, INC. Pharmaceutical compositions and methods for alleviating gastrointestinal symptoms induced by nonsteroidal anti-inflammatory drugs
WO1999012524A1 (en) * 1997-09-11 1999-03-18 Nycomed Danmark A/S MODIFIED RELEASE MULTIPLE-UNITS COMPOSITIONS OF NON-STEROID ANTI-INFLAMMATORY DRUG SUBSTANCES (NSAIDs)
JP2906528B2 (en) * 1990-02-14 1999-06-21 大正製薬株式会社 Solid preparation for internal use with enhanced absorption
WO2000015195A1 (en) * 1998-09-10 2000-03-23 Nycomed Danmark A/S Quick release pharmaceutical compositions of drug substances

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3290970B2 (en) * 1998-07-22 2002-06-10 山之内製薬株式会社 Solid preparation containing poorly soluble NSAIDs
JP2001247481A (en) * 2000-03-06 2001-09-11 Taisho Pharmaceut Co Ltd Medicinal composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3434707A1 (en) * 1983-10-07 1985-04-18 Laboratorio Italiano Biochimico e Farmaceutico LISAPHARMA S.p.A., Erba, Como Non-ulcerogenic pharmaceutical compositions having anti-inflammatory and/or analgesic activity
JP2906528B2 (en) * 1990-02-14 1999-06-21 大正製薬株式会社 Solid preparation for internal use with enhanced absorption
EP0465235A1 (en) * 1990-07-03 1992-01-08 McNEIL-PPC, INC. Pharmaceutical compositions and methods for alleviating gastrointestinal symptoms induced by nonsteroidal anti-inflammatory drugs
WO1999012524A1 (en) * 1997-09-11 1999-03-18 Nycomed Danmark A/S MODIFIED RELEASE MULTIPLE-UNITS COMPOSITIONS OF NON-STEROID ANTI-INFLAMMATORY DRUG SUBSTANCES (NSAIDs)
WO2000015195A1 (en) * 1998-09-10 2000-03-23 Nycomed Danmark A/S Quick release pharmaceutical compositions of drug substances

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 199930, Derwent World Patents Index; Class A96, AN 1991-358401, XP002307543 *

Also Published As

Publication number Publication date
JP2012021025A (en) 2012-02-02
JP2009513512A (en) 2009-04-02
WO2005004915A2 (en) 2005-01-20

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