WO2004069177A3 - Methods for modulating an inflammatory response - Google Patents

Methods for modulating an inflammatory response Download PDF

Info

Publication number
WO2004069177A3
WO2004069177A3 PCT/US2004/002767 US2004002767W WO2004069177A3 WO 2004069177 A3 WO2004069177 A3 WO 2004069177A3 US 2004002767 W US2004002767 W US 2004002767W WO 2004069177 A3 WO2004069177 A3 WO 2004069177A3
Authority
WO
WIPO (PCT)
Prior art keywords
modulating
methods
inflammatory response
wsx
animal
Prior art date
Application number
PCT/US2004/002767
Other languages
French (fr)
Other versions
WO2004069177A2 (en
Inventor
Christopher Hunter
Alejandro Villarino
Original Assignee
Univ Pennsylvania
Christopher Hunter
Alejandro Villarino
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2004/002646 external-priority patent/WO2004069173A2/en
Application filed by Univ Pennsylvania, Christopher Hunter, Alejandro Villarino filed Critical Univ Pennsylvania
Priority to EP04707360A priority Critical patent/EP1587483A4/en
Priority to JP2006503215A priority patent/JP4909069B2/en
Priority to AU2004209967A priority patent/AU2004209967B9/en
Priority to MXPA05008131A priority patent/MXPA05008131A/en
Priority to CA2514641A priority patent/CA2514641C/en
Publication of WO2004069177A2 publication Critical patent/WO2004069177A2/en
Publication of WO2004069177A3 publication Critical patent/WO2004069177A3/en
Priority to AU2009203080A priority patent/AU2009203080B9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The inventive subject matter relates to novel methods for modulating an immune response in an animal, which comprises administering to said animal an effective amount of an agent that increases IL-27R/WSX-1 activity. Further, the inventive subject matter relates to pharmaceutical compositions comprising an effective amount of an agent that increases IL-27R/WSX-1 activity.
PCT/US2004/002767 2003-01-31 2004-02-02 Methods for modulating an inflammatory response WO2004069177A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP04707360A EP1587483A4 (en) 2003-01-31 2004-02-02 Methods for modulating an inflammatory response
JP2006503215A JP4909069B2 (en) 2003-01-31 2004-02-02 Methods for modulating inflammatory responses
AU2004209967A AU2004209967B9 (en) 2003-01-31 2004-02-02 Methods for modulating an inflammatory response
MXPA05008131A MXPA05008131A (en) 2003-01-31 2004-02-02 Methods for modulating an inflammatory response.
CA2514641A CA2514641C (en) 2003-01-31 2004-02-02 Methods for modulating an inflammatory response
AU2009203080A AU2009203080B9 (en) 2003-01-31 2009-07-29 Methods for Modulating an Inflammatory Response

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US44449403P 2003-01-31 2003-01-31
US60/444,494 2003-01-31
US51907403P 2003-11-10 2003-11-10
US60/519,074 2003-11-10
PCT/US2004/002646 WO2004069173A2 (en) 2003-01-31 2004-01-30 Methods for modulating an inflammatory response
USPCT/US04/02646 2004-01-30

Publications (2)

Publication Number Publication Date
WO2004069177A2 WO2004069177A2 (en) 2004-08-19
WO2004069177A3 true WO2004069177A3 (en) 2006-01-12

Family

ID=32851399

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/002767 WO2004069177A2 (en) 2003-01-31 2004-02-02 Methods for modulating an inflammatory response

Country Status (2)

Country Link
MX (1) MXPA05008131A (en)
WO (1) WO2004069177A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4839434B2 (en) * 2005-03-14 2011-12-21 千葉県 Pharmaceutical formulation containing p28 molecule or gene thereof
US20100008917A1 (en) * 2006-08-25 2010-01-14 Nancy Hosken Treatment of aplastic anemia
EP2054075A1 (en) * 2006-08-25 2009-05-06 Zymogenetics, Inc. Treatment of graft-versus-host disease
RU2644346C2 (en) 2011-06-01 2018-02-08 Интрексон Актобиотикс Н.В. System of polycistronic expression for bacteria
CA3011331A1 (en) 2016-01-14 2017-07-20 Intrexon Actobiotics N.V. Compositions and methods for the treatment of type 1 diabetes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of EP1587483A4 *
SPRECHER C. ET AL: "Cloning and Characterization of a Novel Clas 1 Cytokine Receptor.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 246, 1998, pages 82 - 90, XP002174914 *

Also Published As

Publication number Publication date
WO2004069177A2 (en) 2004-08-19
MXPA05008131A (en) 2005-10-05

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