WO2008087367A3 - Substituted (phenylthiazolyl)-phenyl-propan-1-one and (phenyloxazodyl)-phenyl-propan-1-one derivatives, preparations and uses of same - Google Patents

Substituted (phenylthiazolyl)-phenyl-propan-1-one and (phenyloxazodyl)-phenyl-propan-1-one derivatives, preparations and uses of same Download PDF

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Publication number
WO2008087367A3
WO2008087367A3 PCT/FR2007/052635 FR2007052635W WO2008087367A3 WO 2008087367 A3 WO2008087367 A3 WO 2008087367A3 FR 2007052635 W FR2007052635 W FR 2007052635W WO 2008087367 A3 WO2008087367 A3 WO 2008087367A3
Authority
WO
WIPO (PCT)
Prior art keywords
propan
phenyl
phenylthiazolyl
substituted
same
Prior art date
Application number
PCT/FR2007/052635
Other languages
French (fr)
Other versions
WO2008087367A2 (en
Inventor
Jean-Francois Delhomel
Original Assignee
Genfit
Jean-Francois Delhomel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit, Jean-Francois Delhomel filed Critical Genfit
Publication of WO2008087367A2 publication Critical patent/WO2008087367A2/en
Publication of WO2008087367A3 publication Critical patent/WO2008087367A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Abstract

The invention relates to substituted (phenylthiazolyl)-phenyl-propan-1-one and phenyloxazolyl)-phenyl-propan-1-one derivative compounds, pharmaceutical compositions comprising same, and therapeutic uses thereof, especially in the fields of human and animal health.
PCT/FR2007/052635 2006-12-29 2007-12-28 Substituted (phenylthiazolyl)-phenyl-propan-1-one and (phenyloxazodyl)-phenyl-propan-1-one derivatives, preparations and uses of same WO2008087367A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0656065 2006-12-29
FR0656065A FR2910893A1 (en) 2006-12-29 2006-12-29 New Phenylthiazolyl/phenyloxazolyl derivatives are peroxisome proliferator-activated receptor agonist useful to treat e.g. diabetic, dyslipidemia, cardiovascular disease, hypertension, inflammatory diseases and cerebral ischaemia

Publications (2)

Publication Number Publication Date
WO2008087367A2 WO2008087367A2 (en) 2008-07-24
WO2008087367A3 true WO2008087367A3 (en) 2008-11-06

Family

ID=38257586

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2007/052635 WO2008087367A2 (en) 2006-12-29 2007-12-28 Substituted (phenylthiazolyl)-phenyl-propan-1-one and (phenyloxazodyl)-phenyl-propan-1-one derivatives, preparations and uses of same

Country Status (2)

Country Link
FR (1) FR2910893A1 (en)
WO (1) WO2008087367A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009002514A1 (en) * 2009-04-21 2010-10-28 Evonik Degussa Gmbh Process for the preparation of substituted 1,4-quinone methides
CN102724978A (en) * 2009-08-14 2012-10-10 塞伦尼斯治疗公司 Use of ppar delta ligands for the treatment or prevention of inflammation or energy metabolism/production related diseases
WO2011107494A1 (en) 2010-03-03 2011-09-09 Sanofi Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof
EP2582709B1 (en) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US20150166528A1 (en) 2012-06-14 2015-06-18 Basf Se Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests
CN103588767B (en) * 2013-11-20 2016-01-20 苏州明锐医药科技有限公司 The preparation method of Da Lafeini
CN108658908B (en) 2017-07-31 2019-05-10 广州必贝特医药技术有限公司 1,3- bis- replaces ketene compounds and its application
WO2021169769A1 (en) * 2020-02-28 2021-09-02 四川科伦博泰生物医药股份有限公司 Aromatic compound and pharmaceutical composition and use thereof
WO2022238448A1 (en) 2021-05-11 2022-11-17 Genfit Elafibranor derivatives agonists of ppar for use in the treatment of sepsis
WO2022238450A1 (en) 2021-05-11 2022-11-17 Genfit Ppar-agonists for use in the treatment of liver failure

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002050048A1 (en) * 2000-12-20 2002-06-27 Glaxo Group Limited Thia- and oxazoles and their use as ppars activators
WO2002059098A1 (en) * 2000-12-20 2002-08-01 Glaxo Group Limited Thiazole and oxazole derivatives as activators of human peroxisome proliferator activated receptors
EP1310494A1 (en) * 2000-08-11 2003-05-14 Nippon Chemiphar Co., Ltd. PPAR (delta) ACTIVATORS
EP1371650A1 (en) * 2001-03-23 2003-12-17 Nippon Chemiphar Co., Ltd. Activator for peroxisome proliferator-activated receptor
EP1424330A1 (en) * 2001-08-10 2004-06-02 Nippon Chemiphar Co., Ltd. Activator for peroxisome proliferator-responsive receptor delta
EP1666472A1 (en) * 2003-09-22 2006-06-07 Ono Pharmaceutical Co., Ltd. Phenylacetic acid derivative, process for producing the same, and use

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1310494A1 (en) * 2000-08-11 2003-05-14 Nippon Chemiphar Co., Ltd. PPAR (delta) ACTIVATORS
WO2002050048A1 (en) * 2000-12-20 2002-06-27 Glaxo Group Limited Thia- and oxazoles and their use as ppars activators
WO2002059098A1 (en) * 2000-12-20 2002-08-01 Glaxo Group Limited Thiazole and oxazole derivatives as activators of human peroxisome proliferator activated receptors
EP1371650A1 (en) * 2001-03-23 2003-12-17 Nippon Chemiphar Co., Ltd. Activator for peroxisome proliferator-activated receptor
EP1424330A1 (en) * 2001-08-10 2004-06-02 Nippon Chemiphar Co., Ltd. Activator for peroxisome proliferator-responsive receptor delta
EP1666472A1 (en) * 2003-09-22 2006-06-07 Ono Pharmaceutical Co., Ltd. Phenylacetic acid derivative, process for producing the same, and use

Also Published As

Publication number Publication date
WO2008087367A2 (en) 2008-07-24
FR2910893A1 (en) 2008-07-04

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