WO2004046118A3 - 2-4-(di-phenyl-amino)-pyrimidine derivatives useful for treating hyper-proliferative disorders - Google Patents
2-4-(di-phenyl-amino)-pyrimidine derivatives useful for treating hyper-proliferative disorders Download PDFInfo
- Publication number
- WO2004046118A3 WO2004046118A3 PCT/US2003/014294 US0314294W WO2004046118A3 WO 2004046118 A3 WO2004046118 A3 WO 2004046118A3 US 0314294 W US0314294 W US 0314294W WO 2004046118 A3 WO2004046118 A3 WO 2004046118A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- amino
- phenyl
- proliferative disorders
- pyrimidine derivatives
- derivatives useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003299474A AU2003299474A1 (en) | 2002-05-06 | 2003-05-06 | 2-4-(di-phenyl-amino)-pyrimidine derivatives useful for treating hyper-proliferative disorders |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37832902P | 2002-05-06 | 2002-05-06 | |
US60/378,329 | 2002-05-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004046118A2 WO2004046118A2 (en) | 2004-06-03 |
WO2004046118A3 true WO2004046118A3 (en) | 2004-08-12 |
Family
ID=29420382
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/013604 WO2003095448A1 (en) | 2002-05-06 | 2003-05-02 | Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders |
PCT/US2003/014294 WO2004046118A2 (en) | 2002-05-06 | 2003-05-06 | 2-4-(di-phenyl-amino)-pyrimidine derivatives useful for treating hyper-proliferative disorders |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/013604 WO2003095448A1 (en) | 2002-05-06 | 2003-05-02 | Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders |
Country Status (2)
Country | Link |
---|---|
AU (2) | AU2003231231A1 (en) |
WO (2) | WO2003095448A1 (en) |
Cited By (11)
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US7989448B2 (en) | 2005-01-19 | 2011-08-02 | Rigel Pharmaceuticals, Inc. | Prodrugs of 2,4-pyrimidinediamine compounds and their uses |
US8557806B2 (en) | 2002-07-29 | 2013-10-15 | Rigel Pharmaceuticals, Inc. | Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds |
US8604042B2 (en) | 2005-11-01 | 2013-12-10 | Targegen, Inc. | Bi-aryl meta-pyrimidine inhibitors of kinases |
US8785692B2 (en) | 2007-03-12 | 2014-07-22 | Bayer Cropscience Ag | Substituted phenylamidines and the use thereof as fungicides |
US8835430B2 (en) | 2002-02-01 | 2014-09-16 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds and their uses |
US8952027B2 (en) | 2008-04-16 | 2015-02-10 | Portola Pharmaceuticals, Inc. | Inhibitors of syk and JAK protein kinases |
US9012462B2 (en) | 2008-05-21 | 2015-04-21 | Ariad Pharmaceuticals, Inc. | Phosphorous derivatives as kinase inhibitors |
US9248190B2 (en) | 2005-06-08 | 2016-02-02 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the JAK pathway |
US9273077B2 (en) | 2008-05-21 | 2016-03-01 | Ariad Pharmaceuticals, Inc. | Phosphorus derivatives as kinase inhibitors |
US9359308B2 (en) | 2011-11-23 | 2016-06-07 | Portola Pharmaceuticals, Inc. | Pyrazine kinase inhibitors |
JP7202315B2 (en) | 2017-05-26 | 2023-01-11 | キャンサー・リサーチ・テクノロジー・リミテッド | BCL6 inhibitors derived from benzimidazolones |
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2003
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- 2003-05-06 AU AU2003299474A patent/AU2003299474A1/en not_active Abandoned
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US9018204B1 (en) | 2002-02-01 | 2015-04-28 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds and their uses |
US9416112B2 (en) | 2002-02-01 | 2016-08-16 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds and their uses |
US9346765B2 (en) | 2002-02-01 | 2016-05-24 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds and their uses |
US8835430B2 (en) | 2002-02-01 | 2014-09-16 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds and their uses |
US8557806B2 (en) | 2002-07-29 | 2013-10-15 | Rigel Pharmaceuticals, Inc. | Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds |
US8476263B2 (en) | 2005-01-19 | 2013-07-02 | Rigel Pharmaceuticals, Inc. | Prodrugs of 2,4-pyrimidinediamine compounds and their uses |
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WO2004046118A2 (en) | 2004-06-03 |
AU2003299474A1 (en) | 2004-06-15 |
WO2003095448A1 (en) | 2003-11-20 |
AU2003231231A1 (en) | 2003-11-11 |
AU2003299474A8 (en) | 2004-06-15 |
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