WO2003057224A1 - Inducteur d'apoptose - Google Patents

Inducteur d'apoptose Download PDF

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Publication number
WO2003057224A1
WO2003057224A1 PCT/JP2002/013663 JP0213663W WO03057224A1 WO 2003057224 A1 WO2003057224 A1 WO 2003057224A1 JP 0213663 W JP0213663 W JP 0213663W WO 03057224 A1 WO03057224 A1 WO 03057224A1
Authority
WO
WIPO (PCT)
Prior art keywords
apoptosis
inductor
apoptosis inductor
erythrodiol
uvaol
Prior art date
Application number
PCT/JP2002/013663
Other languages
English (en)
Japanese (ja)
Inventor
Hisami Shinohara
Gou Shinohara
Noriyasu Kuno
Original Assignee
The Nisshin Oillio, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Nisshin Oillio, Ltd. filed Critical The Nisshin Oillio, Ltd.
Priority to JP2003557582A priority Critical patent/JPWO2003057224A1/ja
Priority to AU2002367429A priority patent/AU2002367429A1/en
Publication of WO2003057224A1 publication Critical patent/WO2003057224A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms

Abstract

L'invention concerne un inducteur d'apoptose contenant en tant qu'ingrédient actif un composé ayant l'effet d'induire une apoptose, lequel est choisi dans le groupe contenant acide maslinique, érythrodiol, uvéaol, bétuline, leurs sels physiologiquement acceptables ainsi que des dérivés de ceux-ci ; un aliment ou une boisson pour l'induction de l'apoptose ; une matière afférente ainsi qu'une préparation pharmaceutique contenant l'inducteur d'apoptose.
PCT/JP2002/013663 2001-12-28 2002-12-26 Inducteur d'apoptose WO2003057224A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2003557582A JPWO2003057224A1 (ja) 2001-12-28 2002-12-26 アポトーシス誘導剤
AU2002367429A AU2002367429A1 (en) 2001-12-28 2002-12-26 Apoptosis inductor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001401506 2001-12-28
JP2001-401506 2001-12-28

Publications (1)

Publication Number Publication Date
WO2003057224A1 true WO2003057224A1 (fr) 2003-07-17

Family

ID=19189787

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/013663 WO2003057224A1 (fr) 2001-12-28 2002-12-26 Inducteur d'apoptose

Country Status (3)

Country Link
JP (1) JPWO2003057224A1 (fr)
AU (1) AU2002367429A1 (fr)
WO (1) WO2003057224A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009121992A2 (fr) 2008-04-03 2009-10-08 Biomaslinic S.L. Utilisation de l'acide maslinique dans le traitement de pathologies et de leurs symptômes par inhibition de cox-2
ES2333638A1 (es) * 2009-07-29 2010-02-24 Universidad De Granada Uso del acido maslinico para el tratamiento de dolores de naturaleza nociceptiva, inflamatoria y neurogenica.
CN102232956A (zh) * 2010-03-05 2011-11-09 中国科学院上海生命科学研究院 一种防治代谢性疾病的化合物及其用途
JP2021013326A (ja) * 2019-07-12 2021-02-12 日本製粉株式会社 肉体的疲労及び疲労感を予防又は改善するオレアナン型トリテルペンを含有する組成物

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000186A (en) * 1973-11-07 1976-12-28 Biorex Laboratories, Limited Erythrodiol derivatives
WO1998051294A2 (fr) * 1997-05-16 1998-11-19 The Board Of Trustees Of The University Of Illinois Procede et composition de traitement anti-cancer
WO1998051293A1 (fr) * 1997-05-16 1998-11-19 The Board Of Trustees Of The University Of Illinois Utilisation de derives de l'acide betulinique pour le traitement et la prevention des melanomes
JPH11209275A (ja) * 1998-01-23 1999-08-03 Meiji Seika Kaisha Ltd 肝疾患予防治療剤
WO2000024762A1 (fr) * 1998-10-28 2000-05-04 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Acide betulinique et derives de cet acide pour le traitement de tumeurs neuroectodermiques
WO2001090136A2 (fr) * 2000-05-23 2001-11-29 Univerzita Palackeho V Olomouci Derives de triterpenoide
WO2002009719A1 (fr) * 2000-07-31 2002-02-07 The Nisshin Oillio, Ltd. Agents antitumoraux
WO2002043736A1 (fr) * 2000-11-30 2002-06-06 The Nisshin Oillio, Ltd. Aliments et boissons embellissants et preparations perorales embellissantes
WO2002052956A1 (fr) * 2000-12-27 2002-07-11 The Nisshin Oillio, Ltd. Boisson ou aliment antitumoral
WO2002078685A1 (fr) * 2001-03-30 2002-10-10 The Nisshin_Oillio, Ltd. Medicaments pour une lesion vasculaire
WO2003011267A1 (fr) * 2001-07-31 2003-02-13 The Nisshin Oillio, Ltd. Medicaments anti-obesite et ses substances

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000186A (en) * 1973-11-07 1976-12-28 Biorex Laboratories, Limited Erythrodiol derivatives
WO1998051294A2 (fr) * 1997-05-16 1998-11-19 The Board Of Trustees Of The University Of Illinois Procede et composition de traitement anti-cancer
WO1998051293A1 (fr) * 1997-05-16 1998-11-19 The Board Of Trustees Of The University Of Illinois Utilisation de derives de l'acide betulinique pour le traitement et la prevention des melanomes
JPH11209275A (ja) * 1998-01-23 1999-08-03 Meiji Seika Kaisha Ltd 肝疾患予防治療剤
WO2000024762A1 (fr) * 1998-10-28 2000-05-04 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Acide betulinique et derives de cet acide pour le traitement de tumeurs neuroectodermiques
WO2001090136A2 (fr) * 2000-05-23 2001-11-29 Univerzita Palackeho V Olomouci Derives de triterpenoide
WO2002009719A1 (fr) * 2000-07-31 2002-02-07 The Nisshin Oillio, Ltd. Agents antitumoraux
WO2002043736A1 (fr) * 2000-11-30 2002-06-06 The Nisshin Oillio, Ltd. Aliments et boissons embellissants et preparations perorales embellissantes
WO2002052956A1 (fr) * 2000-12-27 2002-07-11 The Nisshin Oillio, Ltd. Boisson ou aliment antitumoral
WO2002078685A1 (fr) * 2001-03-30 2002-10-10 The Nisshin_Oillio, Ltd. Medicaments pour une lesion vasculaire
WO2002078468A1 (fr) * 2001-03-30 2002-10-10 The Nisshin Oillio, Ltd. Aliment ou boisson pour maladie ou trouble vasculaire
WO2003011267A1 (fr) * 2001-07-31 2003-02-13 The Nisshin Oillio, Ltd. Medicaments anti-obesite et ses substances

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ASSEFA, H ET AL., BIOORG. MED. CHEM., vol. 9, no. 14, 1999, pages 1889 - 1894, XP004171604 *
HATA,K ET AL., J. NATURAL PRODUCTS, vol. 65, no. 5, 2002, pages 645 - 648, XP002967006 *
YASUKAWA,K, JOURNAL OF THE JAPAN OIL CHEMISTS' SOCIETY, vol. 49, no. 6, 2000, pages 571 - 583, XP002948553 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009121992A2 (fr) 2008-04-03 2009-10-08 Biomaslinic S.L. Utilisation de l'acide maslinique dans le traitement de pathologies et de leurs symptômes par inhibition de cox-2
ES2328999A1 (es) * 2008-04-03 2009-11-19 Biomaslinic S.L. Uso del acido maslinico para el tratamiento de patologias y sus sintomas mediante la inhibicion de cox-2.
WO2009121992A3 (fr) * 2008-04-03 2010-01-07 Biomaslinic S.L. Utilisation de l'acide maslinique dans le traitement de pathologies et de leurs symptômes par inhibition de cox-2
ES2333638A1 (es) * 2009-07-29 2010-02-24 Universidad De Granada Uso del acido maslinico para el tratamiento de dolores de naturaleza nociceptiva, inflamatoria y neurogenica.
WO2011015692A2 (fr) * 2009-07-29 2011-02-10 Universidad De Granada Utilisation de l'acide maslinique pour le traitement de douleurs de nature nociceptive, inflammatoire et neurogénique
WO2011015692A3 (fr) * 2009-07-29 2011-03-31 Universidad De Granada Utilisation de l'acide maslinique pour le traitement de douleurs de nature nociceptive, inflammatoire et neurogénique
CN102232956A (zh) * 2010-03-05 2011-11-09 中国科学院上海生命科学研究院 一种防治代谢性疾病的化合物及其用途
JP2021013326A (ja) * 2019-07-12 2021-02-12 日本製粉株式会社 肉体的疲労及び疲労感を予防又は改善するオレアナン型トリテルペンを含有する組成物
JP7371851B2 (ja) 2019-07-12 2023-10-31 株式会社ニップン 肉体的疲労及び疲労感を予防又は改善するオレアナン型トリテルペンを含有する組成物

Also Published As

Publication number Publication date
JPWO2003057224A1 (ja) 2005-08-25
AU2002367429A1 (en) 2003-07-24

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