WO2003039326A3 - Methode de determination en continu et de façon non invasive des caracteristiques physiologiques - Google Patents

Methode de determination en continu et de façon non invasive des caracteristiques physiologiques Download PDF

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Publication number
WO2003039326A3
WO2003039326A3 PCT/US2001/046855 US0146855W WO03039326A3 WO 2003039326 A3 WO2003039326 A3 WO 2003039326A3 US 0146855 W US0146855 W US 0146855W WO 03039326 A3 WO03039326 A3 WO 03039326A3
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WIPO (PCT)
Prior art keywords
blood
level sensor
converter
patient
changes
Prior art date
Application number
PCT/US2001/046855
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English (en)
Other versions
WO2003039326A8 (fr
WO2003039326A2 (fr
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Mills Alexander K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mills Alexander K filed Critical Mills Alexander K
Priority to MXPA04004286A priority Critical patent/MXPA04004286A/es
Priority to PCT/US2001/046855 priority patent/WO2003039326A2/fr
Priority to CA002466012A priority patent/CA2466012A1/fr
Priority to AU2001297917A priority patent/AU2001297917B2/en
Priority to EP01274207A priority patent/EP1450672A4/fr
Priority to JP2003541424A priority patent/JP2005507298A/ja
Publication of WO2003039326A2 publication Critical patent/WO2003039326A2/fr
Publication of WO2003039326A3 publication Critical patent/WO2003039326A3/fr
Publication of WO2003039326A8 publication Critical patent/WO2003039326A8/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6825Hand
    • A61B5/6826Finger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02028Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055Simultaneously evaluating both cardiovascular condition and temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14539Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4821Determining level or depth of anaesthesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683Means for maintaining contact with the body
    • A61B5/6838Clamps or clips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0242Operational features adapted to measure environmental factors, e.g. temperature, pollution
    • A61B2560/0247Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
    • A61B2560/0261Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using hydrostatic pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0285Measuring or recording phase velocity of blood waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/029Measuring or recording blood output from the heart, e.g. minute volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552Details of sensors specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Optics & Photonics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Vascular Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

L'invention concerne des méthodes permettant de contrôler, de façon non invasive, des caractéristiques physiologiques du sang d'un patient. Pour déterminer la concentration des constituants sanguins, il suffit de comparer l'absorbance du rayonnement avec différents paramètres, tels que la longueur du trajet optique et la pression sanguine. Pour faire varier la pression, il suffit de modifier la hauteur des sondes par rapport au coeur du patient. Pour déterminer le pH sanguin, il suffit de comparer l'absorbance du sang avec différentes longueurs d'ondes. Ces méthodes permettent également de déterminer avec précision la température du sang et, par conséquent, la température centrale du patient. Les méthodes de l'invention permettent également de déterminer, de façon non invasive, des caractéristiques du débit cardiaque et de la pression sanguine.
PCT/US2001/046855 2001-11-07 2001-11-07 Methode de determination en continu et de façon non invasive des caracteristiques physiologiques WO2003039326A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
MXPA04004286A MXPA04004286A (es) 2001-11-07 2001-11-07 Metodo para la determinacion continua no invasiva de caracteristicas fisiologicas.
PCT/US2001/046855 WO2003039326A2 (fr) 2001-11-07 2001-11-07 Methode de determination en continu et de façon non invasive des caracteristiques physiologiques
CA002466012A CA2466012A1 (fr) 2001-11-07 2001-11-07 Methode de determination en continu et de facon non invasive des caracteristiques physiologiques
AU2001297917A AU2001297917B2 (en) 2001-11-07 2001-11-07 Method for noninvasive continuous determination of physiologic characteristics
EP01274207A EP1450672A4 (fr) 2001-11-07 2001-11-07 Methode de determination en continu et de fa on non invasive des caracteristiques physiologiques
JP2003541424A JP2005507298A (ja) 2001-11-07 2001-11-07 生理学的特性を,非侵襲的に連続測定する方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/046855 WO2003039326A2 (fr) 2001-11-07 2001-11-07 Methode de determination en continu et de façon non invasive des caracteristiques physiologiques

Publications (3)

Publication Number Publication Date
WO2003039326A2 WO2003039326A2 (fr) 2003-05-15
WO2003039326A3 true WO2003039326A3 (fr) 2003-07-24
WO2003039326A8 WO2003039326A8 (fr) 2007-09-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046855 WO2003039326A2 (fr) 2001-11-07 2001-11-07 Methode de determination en continu et de façon non invasive des caracteristiques physiologiques

Country Status (6)

Country Link
EP (1) EP1450672A4 (fr)
JP (1) JP2005507298A (fr)
AU (1) AU2001297917B2 (fr)
CA (1) CA2466012A1 (fr)
MX (1) MXPA04004286A (fr)
WO (1) WO2003039326A2 (fr)

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US8219170B2 (en) 2006-09-20 2012-07-10 Nellcor Puritan Bennett Llc System and method for practicing spectrophotometry using light emitting nanostructure devices
US8265724B2 (en) 2007-03-09 2012-09-11 Nellcor Puritan Bennett Llc Cancellation of light shunting
US8280469B2 (en) 2007-03-09 2012-10-02 Nellcor Puritan Bennett Llc Method for detection of aberrant tissue spectra
US8315685B2 (en) 2006-09-27 2012-11-20 Nellcor Puritan Bennett Llc Flexible medical sensor enclosure
US8600469B2 (en) 2005-09-29 2013-12-03 Covidien Lp Medical sensor and technique for using the same

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JP6055688B2 (ja) 2013-01-31 2016-12-27 日本光電工業株式会社 生体信号測定システム、生体信号測定装置、および生体信号測定装置の制御プログラム
WO2014198868A1 (fr) * 2013-06-13 2014-12-18 Koninklijke Philips N.V. Dispositif et procédé pour déterminer une pression partielle de dioxyde de carbone chez un sujet d'intérêt
JP6511471B2 (ja) 2014-03-25 2019-05-15 ブライトシード・エルエルシーBriteseed,Llc 脈管検出器及び検出方法
ES2892526T3 (es) 2015-02-19 2022-02-04 Briteseed Llc Sistema para determinar el tamaño de un vaso mediante absorción de luz
EP3545830B1 (fr) 2015-02-19 2022-01-05 Briteseed, LLC Système pour déterminer le bord d'un vaisseau
JP7057277B2 (ja) 2015-10-08 2022-04-19 ブライトシード・エルエルシー 脈管サイズを決定するシステム及びその方法
EP3413792B1 (fr) * 2016-02-12 2023-12-13 Briteseed, LLC Détermination de la présence d'un vaisseau dans une région proche de l'extrémité de travail d'un instrument chirurgical
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EP4026489A1 (fr) 2016-08-30 2022-07-13 Briteseed, LLC Système et procédé permettant de déterminer la taille de vaisseau avec une compensation de distorsion angulaire
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JP7313353B2 (ja) 2017-12-22 2023-07-24 ブライトシード・エルエルシー 組織又はアーチファクト特性を決定するために使用される小型システム
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Patent Citations (6)

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US4968137A (en) * 1986-12-05 1990-11-06 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University Devices and procedures for in vitro testing of pulse oximetry monitors
US6222189B1 (en) * 1992-07-15 2001-04-24 Optix, Lp Methods of enhancing optical signals by mechanical manipulation in non-invasive testing
US5638816A (en) * 1995-06-07 1997-06-17 Masimo Corporation Active pulse blood constituent monitoring
US5978691A (en) * 1996-07-19 1999-11-02 Mills; Alexander Knight Device and method for noninvasive continuous determination of blood gases, pH, hemoglobin level, and oxygen content
US5964701A (en) * 1996-10-24 1999-10-12 Massachusetts Institute Of Technology Patient monitoring finger ring sensor
US6334065B1 (en) * 1998-06-03 2001-12-25 Masimo Corporation Stereo pulse oximeter

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8600469B2 (en) 2005-09-29 2013-12-03 Covidien Lp Medical sensor and technique for using the same
US8219170B2 (en) 2006-09-20 2012-07-10 Nellcor Puritan Bennett Llc System and method for practicing spectrophotometry using light emitting nanostructure devices
US8315685B2 (en) 2006-09-27 2012-11-20 Nellcor Puritan Bennett Llc Flexible medical sensor enclosure
US7684842B2 (en) 2006-09-29 2010-03-23 Nellcor Puritan Bennett Llc System and method for preventing sensor misuse
US8265724B2 (en) 2007-03-09 2012-09-11 Nellcor Puritan Bennett Llc Cancellation of light shunting
US8280469B2 (en) 2007-03-09 2012-10-02 Nellcor Puritan Bennett Llc Method for detection of aberrant tissue spectra

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JP2005507298A (ja) 2005-03-17
WO2003039326A8 (fr) 2007-09-07
MXPA04004286A (es) 2004-09-10
AU2001297917A1 (en) 2003-05-19
EP1450672A2 (fr) 2004-09-01
EP1450672A4 (fr) 2005-06-22
WO2003039326A2 (fr) 2003-05-15
CA2466012A1 (fr) 2003-05-15
AU2001297917B2 (en) 2007-11-01

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