WO2001081555A3 - Human kinases - Google Patents

Human kinases Download PDF

Info

Publication number
WO2001081555A3
WO2001081555A3 PCT/US2001/012992 US0112992W WO0181555A3 WO 2001081555 A3 WO2001081555 A3 WO 2001081555A3 US 0112992 W US0112992 W US 0112992W WO 0181555 A3 WO0181555 A3 WO 0181555A3
Authority
WO
WIPO (PCT)
Prior art keywords
pkin
human kinases
provides
kinases
polynucleotides
Prior art date
Application number
PCT/US2001/012992
Other languages
French (fr)
Other versions
WO2001081555A2 (en
Inventor
Henry Yue
Ameena R Gandhi
Catherine M Tribouley
Liam Kearney
Jennifer A Griffin
Danniel B Nguyen
Olga Bandman
Original Assignee
Incyte Genomics Inc
Henry Yue
Ameena R Gandhi
Catherine M Tribouley
Liam Kearney
Jennifer A Griffin
Danniel B Nguyen
Olga Bandman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Henry Yue, Ameena R Gandhi, Catherine M Tribouley, Liam Kearney, Jennifer A Griffin, Danniel B Nguyen, Olga Bandman filed Critical Incyte Genomics Inc
Priority to JP2001578626A priority Critical patent/JP2004511204A/en
Priority to AU2001255573A priority patent/AU2001255573A1/en
Priority to EP01928748A priority patent/EP1297150A2/en
Priority to US10/258,106 priority patent/US20040018185A1/en
Priority to CA002406399A priority patent/CA2406399A1/en
Publication of WO2001081555A2 publication Critical patent/WO2001081555A2/en
Publication of WO2001081555A3 publication Critical patent/WO2001081555A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
PCT/US2001/012992 2000-04-20 2001-04-20 Human kinases WO2001081555A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2001578626A JP2004511204A (en) 2000-04-20 2001-04-20 Human kinase
AU2001255573A AU2001255573A1 (en) 2000-04-20 2001-04-20 Human kinases
EP01928748A EP1297150A2 (en) 2000-04-20 2001-04-20 Human kinases
US10/258,106 US20040018185A1 (en) 2001-04-20 2001-04-20 Human kinases
CA002406399A CA2406399A1 (en) 2000-04-20 2001-04-20 Human kinases

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US19902100P 2000-04-20 2000-04-20
US60/199,021 2000-04-20
US20022600P 2000-04-28 2000-04-28
US60/200,226 2000-04-28
US20233900P 2000-05-05 2000-05-05
US60/202,339 2000-05-05
US20350500P 2000-05-11 2000-05-11
US60/203,505 2000-05-11
US60/205,564 2000-05-18
US20556400P 2000-05-22 2000-05-22
US20773900P 2000-05-26 2000-05-26
US60/207,739 2000-05-26
US20879500P 2000-06-01 2000-06-01
US60/208,795 2000-06-01

Publications (2)

Publication Number Publication Date
WO2001081555A2 WO2001081555A2 (en) 2001-11-01
WO2001081555A3 true WO2001081555A3 (en) 2002-06-27

Family

ID=27569276

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012992 WO2001081555A2 (en) 2000-04-20 2001-04-20 Human kinases

Country Status (4)

Country Link
EP (1) EP1297150A2 (en)
AU (1) AU2001255573A1 (en)
CA (1) CA2406399A1 (en)
WO (1) WO2001081555A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030028004A1 (en) * 2000-12-22 2003-02-06 Millennium Pharmaceuticals, Inc. 68730 and 69112, protein kinase molecules and uses therefor
US6730491B2 (en) 2000-02-29 2004-05-04 Millennium Pharmaceuticals, Inc. 2504, 15977, and 14760, novel protein kinase family members and uses therefor
US6461846B2 (en) * 2000-05-30 2002-10-08 Pe Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
AU2002223950A1 (en) * 2000-09-20 2002-04-02 Qlt Inc. Cancer associated protein kinases and their uses
US6423521B1 (en) 2000-12-28 2002-07-23 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
CA2480635A1 (en) * 2002-03-28 2003-10-09 Allen D. Delaney Cancer associated protein kinases and their uses
CA2496234A1 (en) * 2002-08-21 2004-03-04 Protein Express Co., Ltd. Salt-inducible kinases 2 and use thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861896A2 (en) * 1997-02-28 1998-09-02 Dade Behring Marburg GmbH Cell volume regulated human kinase h-sgk
WO1999025843A2 (en) * 1997-10-22 1999-05-27 The Scripps Research Institute Human checkpoint kinase, hcds1, compositions and methods
WO1999057132A1 (en) * 1998-05-07 1999-11-11 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO2000008180A2 (en) * 1998-08-04 2000-02-17 Immunex Corporation HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS
WO2001090365A2 (en) * 2000-05-19 2001-11-29 Millennium Pharmaceuticals, Inc. Human protein kinase '13305' and uses therefor

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861896A2 (en) * 1997-02-28 1998-09-02 Dade Behring Marburg GmbH Cell volume regulated human kinase h-sgk
WO1999025843A2 (en) * 1997-10-22 1999-05-27 The Scripps Research Institute Human checkpoint kinase, hcds1, compositions and methods
WO1999057132A1 (en) * 1998-05-07 1999-11-11 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO2000008180A2 (en) * 1998-08-04 2000-02-17 Immunex Corporation HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS
WO2001090365A2 (en) * 2000-05-19 2001-11-29 Millennium Pharmaceuticals, Inc. Human protein kinase '13305' and uses therefor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 13 November 1999 (1999-11-13), STRAUSBERG, R.: "xf45d06.x1 NCI_CGAP_Brn50 Homo sapiens cDNA clone IMAGE:2621003 3' similar to TR:O88904 O88904 HOMEODOMAIN-INTERACTING PROTEIN KINASE 1. ;, mRNA sequence.", XP002186883 *
DATABASE EMBL 27 March 2000 (2000-03-27), BIRREN, B. ET AL.: "Homo sapiens chromosome 1 clone RP11-214B13 map 1, WORKING DRAFT SEQUENCE, 25 unordered pieces", XP002186884 *
ISHIKAWA K-I ET AL: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES. X. THE COMPLETE SEQUENCES OF 100 NEW CDNA CLONES FROM BRAIN WHICH CAN CODE FOR LARGE PROTEINS IN VITRO", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 5, no. 3, 30 June 1998 (1998-06-30), pages 169 - 176, XP000980105, ISSN: 1340-2838 *
YOUNG HO KIM ET AL: "HOMEODOMAIN-INTERACTING PROTEIN KINASES, A NOVEL FAMILY OF CO-REPRESSORS FOR HOMEODOMAIN TRANSCRIPTION FACTORS", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 273, no. 40, 2 October 1998 (1998-10-02), pages 25875 - 25879, XP002943633, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
AU2001255573A1 (en) 2001-11-07
WO2001081555A2 (en) 2001-11-01
EP1297150A2 (en) 2003-04-02
CA2406399A1 (en) 2001-11-01

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