WO2001040315A8 - The alginate having low molecular weight, methods of manufacturing it and its use - Google Patents

The alginate having low molecular weight, methods of manufacturing it and its use

Info

Publication number
WO2001040315A8
WO2001040315A8 PCT/CN1999/000202 CN9900202W WO0140315A8 WO 2001040315 A8 WO2001040315 A8 WO 2001040315A8 CN 9900202 W CN9900202 W CN 9900202W WO 0140315 A8 WO0140315 A8 WO 0140315A8
Authority
WO
WIPO (PCT)
Prior art keywords
molecular weight
alginate
manufacturing
methods
low molecular
Prior art date
Application number
PCT/CN1999/000202
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001040315A9 (en
WO2001040315A1 (en
Inventor
Chuanxing Yu
Original Assignee
Dalian Yaweite Biology Enginee
Chuanxing Yu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dalian Yaweite Biology Enginee, Chuanxing Yu filed Critical Dalian Yaweite Biology Enginee
Priority to PCT/CN1999/000202 priority Critical patent/WO2001040315A1/en
Priority to AU15027/00A priority patent/AU1502700A/en
Priority to CA002430277A priority patent/CA2430277A1/en
Publication of WO2001040315A1 publication Critical patent/WO2001040315A1/en
Publication of WO2001040315A9 publication Critical patent/WO2001040315A9/en
Publication of WO2001040315A8 publication Critical patent/WO2001040315A8/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734Alginic acid
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The alginic acid or the salts thereof having average molecular weight of between about 5,000 -20,000 daltons and exhibiting intrinsic viscosity of between 1 - 20 measured by the Ubbelohde viscometer are provided. Most of the alginates have molecular weight of between 1,000 - 30,000 daltons. They are prepared form a high molecular weight alginic acid by means of decomposition, ultrafiltration and nanofiltration membran. they are of uses for prevention and treatment of hypertension, primary hyperaldosteronism and for reducing blood sugar.
PCT/CN1999/000202 1999-11-30 1999-11-30 The alginate having low molecular weight, methods of manufacturing it and its use WO2001040315A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/CN1999/000202 WO2001040315A1 (en) 1999-11-30 1999-11-30 The alginate having low molecular weight, methods of manufacturing it and its use
AU15027/00A AU1502700A (en) 1999-11-30 1999-11-30 The alginate having low molecular weight, methods of manufacturing it and its use
CA002430277A CA2430277A1 (en) 1999-11-30 1999-11-30 The alginate having low molecular weight, methods of manufacturing it and its use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN1999/000202 WO2001040315A1 (en) 1999-11-30 1999-11-30 The alginate having low molecular weight, methods of manufacturing it and its use

Publications (3)

Publication Number Publication Date
WO2001040315A1 WO2001040315A1 (en) 2001-06-07
WO2001040315A9 WO2001040315A9 (en) 2001-12-06
WO2001040315A8 true WO2001040315A8 (en) 2002-03-21

Family

ID=4575155

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN1999/000202 WO2001040315A1 (en) 1999-11-30 1999-11-30 The alginate having low molecular weight, methods of manufacturing it and its use

Country Status (3)

Country Link
AU (1) AU1502700A (en)
CA (1) CA2430277A1 (en)
WO (1) WO2001040315A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1310954C (en) * 2003-04-15 2007-04-18 哈尔滨工程大学 Preparation method of chromium alginate
CN101104649B (en) * 2006-07-12 2011-05-18 谭攸恒 Potassium alginate and composition thereof
WO2009086685A1 (en) * 2007-12-29 2009-07-16 Dalian Yaweite Bioengineering Co., Ltd. An alginic acid with low molecular weight, its salts, uses, preparative methods, pharmaceutical compositions and foods
JP2010187659A (en) * 2009-01-20 2010-09-02 Kao Corp Purified alginic acid or salt thereof
CN104311696B (en) * 2014-09-26 2017-04-26 大连雅威特生物技术股份有限公司 Application of oligomeric sodium alginate in preparation of medicines, health products and salt products
CN112037931B (en) * 2020-07-15 2023-10-20 新疆维吾尔自治区人民医院 Aldosteronism prediction system for use in suspected primary aldosteronism

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1010654B (en) * 1984-08-10 1990-12-05 麦克公司 The preparation method of the solid-state herbicidal composition of bipyridilium quaternary salt
JPS63101302A (en) * 1986-10-17 1988-05-06 Meiji Seika Kaisha Ltd Culture of plant
IT1213384B (en) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan PROCESS FOR THE CONTROLLED PREPARATION OF LOW MOLECULAR WEIGHT GILCOSAMINOGLICANS.
JPS63214192A (en) * 1987-03-03 1988-09-06 Meiji Seika Kaisha Ltd Production of alginic acid oligosaccharide
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
JPH02225422A (en) * 1989-02-28 1990-09-07 Kimitsu Kagaku Kogyo Kk Medicine composition
JPH03273002A (en) * 1990-03-22 1991-12-04 Otsuka Chem Co Ltd Alginic acid decomposition product
JP3024994B2 (en) * 1990-10-31 2000-03-27 マルハ株式会社 Production method and purification method of alginate oligosaccharide
JP2643669B2 (en) * 1990-12-28 1997-08-20 共成製薬株式会社 Algin-containing foods
JP2663408B2 (en) * 1991-05-09 1997-10-15 明治製菓株式会社 Method for promoting plant morphogenesis or differentiation
JPH0517315A (en) * 1991-07-03 1993-01-26 Sankin Kogyo Kk Alginic acid salt impression material composition for dental use
JPH05304974A (en) * 1992-03-06 1993-11-19 Maruha Corp Calcium aliginate oligosaccharide and its production
GB2266532B (en) * 1992-04-28 1996-09-04 Taiyo Fishery Co Ltd Alginate oligosaccharides methods for their production and their use in foodstuffs
CN1089619A (en) * 1993-01-06 1994-07-20 山东烟台西苑制药厂 A kind of production method of propylene glycol alginate sodium sulfate
JP2986324B2 (en) * 1993-11-26 1999-12-06 明治製菓株式会社 Diet / Diabetic Food
JP3825069B2 (en) * 1994-07-14 2006-09-20 マルハ株式会社 Human epidermal keratinocyte activator
CN1081194C (en) * 1996-12-18 2002-03-20 谭攸恒 Process for preparing potassium alginate and its use
JPH1180204A (en) * 1997-09-05 1999-03-26 Nikka Chem Co Ltd Method for hydrolyzing alginic acid and hydrolyzed material
JP3617912B2 (en) * 1997-10-08 2005-02-09 日本原子力研究所 Plant growth promoter

Also Published As

Publication number Publication date
AU1502700A (en) 2001-06-12
WO2001040315A9 (en) 2001-12-06
WO2001040315A1 (en) 2001-06-07
CA2430277A1 (en) 2001-07-06

Similar Documents

Publication Publication Date Title
CA2153867A1 (en) Bioabsorbable branched polymer containing units derived from dioxanone and medical/surgical devices manufactured therefrom
WO2000051662A9 (en) Bioabsorbable, biocompatible polymers for tissue engineering
EP0767191A3 (en) Polymer, preparation process thereof, hairtreating compositions and cosmetic compositions
WO1998051812A3 (en) Polyhydroxyalkanoates for in vivo applications
WO2005012364A3 (en) Complex matrix for biomedical use
WO2006023388A3 (en) Biodegradable diblock copolymers having reverse thermal gelation
AU2003266581A1 (en) Glycolic acid copolymer and method for production thereof
WO2004075923A3 (en) Polymer-factor viii moiety conjugates
WO2004030617A3 (en) Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
NO20045555L (en) Highly soluble branched glucose polymers
WO2003077792A3 (en) Low polydispersity poly-hema compositions
CA2338629A1 (en) Carrageenan compositions, and processes for their production
CA2326510A1 (en) Dextran formulations and method for treatment of inflammatory joint disorders
CA2371031A1 (en) Compositions for treatment of disorders of the oesophagus
CA2331264A1 (en) Compositions and methods for drug delivery
WO2005058366A3 (en) Compositions comprising two different populations of polymer-active agent conjugates
CA2230530A1 (en) Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
CA2228505A1 (en) Fluoroligomer surface modifiers for polymers and articles made therefrom
EP1591132A3 (en) Poly(lactide-co-glycolide) terpolymers and medical devices containing same
EP2305269A3 (en) Immunemodulating oligosaccharides
AU4913699A (en) Biocompatible polymers, preparation method and compositions containing same
WO2011064555A3 (en) Cosmetic composition comprising amphiphilic copolymer
NO20015224D0 (en) Soluble branched polymers of glucose and their preparation
WO2001040315A8 (en) The alginate having low molecular weight, methods of manufacturing it and its use
WO2005084303A3 (en) Interferon-beta polymer conjugates

Legal Events

Date Code Title Description
ENP Entry into the national phase in:

Ref country code: AU

Ref document number: 2000 15027

Kind code of ref document: A

Format of ref document f/p: F

AK Designated states

Kind code of ref document: A1

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: C2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

COP Corrected version of pamphlet

Free format text: PAGE 12, CLAIMS, ADDED

AK Designated states

Kind code of ref document: C1

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

CFP Corrected version of a pamphlet front page

Free format text: UNDER (71) THE NAME AND ITS TRANSLITERATION IN CHINESE CORRECTED

WWE Wipo information: entry into national phase

Ref document number: 998169315

Country of ref document: CN

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
WWE Wipo information: entry into national phase

Ref document number: 2430277

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 10399742

Country of ref document: US