WO2000055332A3 - Human regulators of intracellular phosphorylation - Google Patents

Human regulators of intracellular phosphorylation Download PDF

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Publication number
WO2000055332A3
WO2000055332A3 PCT/US2000/007277 US0007277W WO0055332A3 WO 2000055332 A3 WO2000055332 A3 WO 2000055332A3 US 0007277 W US0007277 W US 0007277W WO 0055332 A3 WO0055332 A3 WO 0055332A3
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WO
WIPO (PCT)
Prior art keywords
hrip
intracellular phosphorylation
regulators
human regulators
provides
Prior art date
Application number
PCT/US2000/007277
Other languages
French (fr)
Other versions
WO2000055332A2 (en
Inventor
Olga Bandman
Y Tom Tang
Henry Yue
Jennifer L Hillman
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Janice Au-Young
Original Assignee
Incyte Pharma Inc
Olga Bandman
Y Tom Tang
Henry Yue
Jennifer L Hillman
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Au Young Janice
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Olga Bandman, Y Tom Tang, Henry Yue, Jennifer L Hillman, Mariah R Baughn, Yalda Azimzai, Dyung Aina M Lu, Au Young Janice filed Critical Incyte Pharma Inc
Priority to JP2000605750A priority Critical patent/JP2002538827A/en
Priority to CA002364739A priority patent/CA2364739A1/en
Priority to EP00918130A priority patent/EP1192257A2/en
Priority to AU38996/00A priority patent/AU3899600A/en
Publication of WO2000055332A2 publication Critical patent/WO2000055332A2/en
Publication of WO2000055332A3 publication Critical patent/WO2000055332A3/en

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    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12N9/14—Hydrolases (3)
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
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    • C12Y207/11013—Protein kinase C (2.7.11.13)
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    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03048—Protein-tyrosine-phosphatase (3.1.3.48)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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Abstract

The invention provides human regulators of intracellular phosphorylation (HRIP) and polynucleotides which identify and encode HRIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HRIP.
PCT/US2000/007277 1999-03-18 2000-03-17 Human regulators of intracellular phosphorylation WO2000055332A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000605750A JP2002538827A (en) 1999-03-18 2000-03-17 Regulator of intracellular phosphorylation
CA002364739A CA2364739A1 (en) 1999-03-18 2000-03-17 Regulators of intracellular phosphorylation
EP00918130A EP1192257A2 (en) 1999-03-18 2000-03-17 Human regulators of intracellular phosphorylation
AU38996/00A AU3899600A (en) 1999-03-18 2000-03-17 Regulators of intracellular phosphorylation

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US12559399P 1999-03-18 1999-03-18
US60/125,593 1999-03-18
US13504999P 1999-05-20 1999-05-20
US60/135,049 1999-05-20
US14318899P 1999-07-09 1999-07-09
US60/143,188 1999-07-09

Publications (2)

Publication Number Publication Date
WO2000055332A2 WO2000055332A2 (en) 2000-09-21
WO2000055332A3 true WO2000055332A3 (en) 2002-01-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/007277 WO2000055332A2 (en) 1999-03-18 2000-03-17 Human regulators of intracellular phosphorylation

Country Status (5)

Country Link
EP (1) EP1192257A2 (en)
JP (1) JP2002538827A (en)
AU (1) AU3899600A (en)
CA (1) CA2364739A1 (en)
WO (1) WO2000055332A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1173587A1 (en) * 1999-04-23 2002-01-23 Ceptyr, Inc. Dsp-10 dual-specificity map kinase phosphatase
DE60027295T2 (en) 1999-05-13 2007-01-18 Johnson & Johnson Pharmaceutical Research & Development, Llc SPHINGOSINEKINASE
CA2383244A1 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases
WO2001012819A2 (en) * 1999-08-13 2001-02-22 Sugen, Inc. Protein phosphatases and diagnosis and treatment of phosphatase-related disorders
WO2001031029A2 (en) * 1999-10-28 2001-05-03 Warner-Lambert Company Human sphingosine kinase gene
EP1257637A2 (en) * 2000-02-14 2002-11-20 Curagen Corporation Sphingosine kinases
CN100384836C (en) 2000-02-29 2008-04-30 三菱制药株式会社 Novel cyclic amide derivatives
WO2001083723A2 (en) * 2000-05-02 2001-11-08 Ceptyr, Inc. Dsp-14 dual-specificity phosphatase
EP1227156A3 (en) * 2001-01-30 2004-01-02 Aeomica, Inc. A human protein kinase domain-containing protein
US20040096865A1 (en) * 2001-02-05 2004-05-20 Kohler Rainer H. Regulation of human tyrosine-specific protein phosphatase
JPWO2003038118A1 (en) * 2001-10-31 2005-02-24 藤沢薬品工業株式会社 Method for evaluating phosphatase inhibitor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039446A2 (en) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins
WO1999000507A1 (en) * 1997-06-27 1999-01-07 Incyte Pharmaceuticals, Inc. Phosphatidylinositol 4,5-bisphosphate 5-phosphatase from human
WO1999001541A1 (en) * 1997-07-01 1999-01-14 Tularik Inc. IKK-α PROTEINS, NUCLEIC ACIDS AND METHODS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039446A2 (en) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins
WO1999000507A1 (en) * 1997-06-27 1999-01-07 Incyte Pharmaceuticals, Inc. Phosphatidylinositol 4,5-bisphosphate 5-phosphatase from human
WO1999001541A1 (en) * 1997-07-01 1999-01-14 Tularik Inc. IKK-α PROTEINS, NUCLEIC ACIDS AND METHODS

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GCG_GENESEQ_D database, accession number V59579 6 January 1999 "Human secreted protein gene 69 clone HETGJ09" *
GROOM, L.A. ET AL.: "Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specific phosphatase", EMBO JOURNAL, vol. 15, no. 14, 15 July 1996 (1996-07-15), pages 3621 - 3632, XP000925967 *
TANOUE, T. ET AL.: "Molecular Cloning and Characterziation of a Novel Dual Specificity Phosphatase, MKP-5", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 28, 9 July 1999 (1999-07-09), pages 19949 - 19956, XP002148678 *

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Publication number Publication date
EP1192257A2 (en) 2002-04-03
WO2000055332A2 (en) 2000-09-21
JP2002538827A (en) 2002-11-19
CA2364739A1 (en) 2000-09-21
AU3899600A (en) 2000-10-04

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