WO2001044448A3 - Human oxidoreductase proteins - Google Patents

Human oxidoreductase proteins Download PDF

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Publication number
WO2001044448A3
WO2001044448A3 PCT/US2000/033158 US0033158W WO0144448A3 WO 2001044448 A3 WO2001044448 A3 WO 2001044448A3 US 0033158 W US0033158 W US 0033158W WO 0144448 A3 WO0144448 A3 WO 0144448A3
Authority
WO
WIPO (PCT)
Prior art keywords
orp
oxidoreductase proteins
human oxidoreductase
provides
proteins
Prior art date
Application number
PCT/US2000/033158
Other languages
French (fr)
Other versions
WO2001044448A2 (en
Inventor
Henry Yue
Preeti Lal
Y Tom Tang
Jennifer L Hillman
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Original Assignee
Incyte Genomics Inc
Henry Yue
Preeti Lal
Y Tom Tang
Jennifer L Hillman
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Henry Yue, Preeti Lal, Y Tom Tang, Jennifer L Hillman, Mariah R Baughn, Yalda Azimzai, Dyung Aina M Lu filed Critical Incyte Genomics Inc
Priority to EP00983992A priority Critical patent/EP1242583A2/en
Priority to AU20675/01A priority patent/AU2067501A/en
Priority to CA002394160A priority patent/CA2394160A1/en
Priority to JP2001545526A priority patent/JP2003516750A/en
Publication of WO2001044448A2 publication Critical patent/WO2001044448A2/en
Publication of WO2001044448A3 publication Critical patent/WO2001044448A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides human oxidoreductase proteins (ORP) and polynucleotides which identify and encode ORP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of ORP.
PCT/US2000/033158 1999-12-16 2000-12-07 Human oxidoreductase proteins WO2001044448A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00983992A EP1242583A2 (en) 1999-12-16 2000-12-07 Human oxidoreductase proteins
AU20675/01A AU2067501A (en) 1999-12-16 2000-12-07 Human oxidoreductase proteins
CA002394160A CA2394160A1 (en) 1999-12-16 2000-12-07 Human oxidoreductase proteins
JP2001545526A JP2003516750A (en) 1999-12-16 2000-12-07 Human oxidoreductase protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17236799P 1999-12-16 1999-12-16
US60/172,367 1999-12-16

Publications (2)

Publication Number Publication Date
WO2001044448A2 WO2001044448A2 (en) 2001-06-21
WO2001044448A3 true WO2001044448A3 (en) 2002-01-17

Family

ID=22627426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/033158 WO2001044448A2 (en) 1999-12-16 2000-12-07 Human oxidoreductase proteins

Country Status (5)

Country Link
EP (1) EP1242583A2 (en)
JP (1) JP2003516750A (en)
AU (1) AU2067501A (en)
CA (1) CA2394160A1 (en)
WO (1) WO2001044448A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020081679A1 (en) * 1999-10-22 2002-06-27 Millennium Pharmaceuticals, Inc. NARC8 programmed cell-death-associated molecules and uses thereof
WO2002018582A2 (en) * 2000-08-31 2002-03-07 Millennium Pharmaceuticals, Inc. 62112, a novel human dehydrogenase and uses thereof
US6613554B2 (en) 2001-03-26 2003-09-02 Applera Corporation Isolated human enzyme, nucleic acid molecules encoding human enzyme, and uses thereof
US20070042361A1 (en) * 2001-03-27 2007-02-22 Rosen Craig A Human secreted proteins
EP1480670A2 (en) * 2002-03-07 2004-12-01 DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung Cg3842 homologous proteins involved in the regulation of energy homeostasis
JP2005527217A (en) * 2002-05-27 2005-09-15 バイエル・ヘルスケア・アクチェンゲゼルシャフト Regulation of a novel human asparagine hydroxylase
WO2004037987A2 (en) * 2002-10-22 2004-05-06 Incyte Corporation Secreted proteins
WO2004069194A2 (en) * 2003-02-03 2004-08-19 The Brigham And Women's Hospital, Inc. Use of the oxidoreductase ncb50r for diagnosings and treating diabetes
WO2004103316A2 (en) * 2003-05-21 2004-12-02 Xenon Genetics Inc. Orp9, a novel therapeutic target for increasing hdl levels
EP1644494A2 (en) * 2003-06-17 2006-04-12 Devgen NV Alcohol dehydrogenase sequences useful for developing compounds for the prevention and/or treatment of metabolic diseases
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BLANCHET M A ET AL.: "Structure and mechanism of cytosolic quinone reductases", BIOCHEM SOC.TRANS., vol. 27, no. 4, August 1999 (1999-08-01), pages 610 - 615, XP000984873 *
DATABASE EMBL 27 April 1999 (1999-04-27), LAI C-H ET AL.: "Homo sapiens CGI-10 protein mRNA, complete cds", XP002162312 *
DATABASE EMBL 30 May 2000 (2000-05-30), LIN W-C ET AL.: "Putative Ubiquinone biosynthesis monooxigenase COQ6 (EC 1.14.13)", XP002163100 *
LAI C-H ET AL.: "Identification of novel human genes evolutionarily conserved in Caenorabditis elegans by comparative proteomics.", GENOME RES., vol. 10, no. 5, May 2000 (2000-05-01), pages 703 - 713, XP002163099 *

Also Published As

Publication number Publication date
JP2003516750A (en) 2003-05-20
WO2001044448A2 (en) 2001-06-21
CA2394160A1 (en) 2001-06-21
EP1242583A2 (en) 2002-09-25
AU2067501A (en) 2001-06-25

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