WO2000012703A3 - Protein transport-associated molecules - Google Patents

Protein transport-associated molecules Download PDF

Info

Publication number
WO2000012703A3
WO2000012703A3 PCT/US1999/019616 US9919616W WO0012703A3 WO 2000012703 A3 WO2000012703 A3 WO 2000012703A3 US 9919616 W US9919616 W US 9919616W WO 0012703 A3 WO0012703 A3 WO 0012703A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein transport
ptam
associated molecules
provides
expression
Prior art date
Application number
PCT/US1999/019616
Other languages
French (fr)
Other versions
WO2000012703A2 (en
Inventor
Y Tom Tang
Preeti Lal
Olga Bandman
Henry Yue
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Chandra Patterson
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Preeti Lal
Olga Bandman
Henry Yue
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Chandra Patterson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Preeti Lal, Olga Bandman, Henry Yue, Neil C Corley, Karl J Guegler, Gina A Gorgone, Mariah R Baughn, Chandra Patterson filed Critical Incyte Pharma Inc
Priority to CA002340794A priority Critical patent/CA2340794A1/en
Priority to JP2000567690A priority patent/JP2002523089A/en
Priority to US09/763,902 priority patent/US6838241B1/en
Priority to EP99942518A priority patent/EP1108019A2/en
Priority to AU55877/99A priority patent/AU5587799A/en
Publication of WO2000012703A2 publication Critical patent/WO2000012703A2/en
Publication of WO2000012703A3 publication Critical patent/WO2000012703A3/en
Priority to US10/986,822 priority patent/US20050130204A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides human protein transport molecules (PTAM) and polynucleotides which identify and encode PTAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of PTAM.
PCT/US1999/019616 1998-08-27 1999-08-26 Protein transport-associated molecules WO2000012703A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002340794A CA2340794A1 (en) 1998-08-27 1999-08-26 Protein transport-associated molecules
JP2000567690A JP2002523089A (en) 1998-08-27 1999-08-26 Protein transport-related molecules
US09/763,902 US6838241B1 (en) 1998-08-27 1999-08-26 Protein transport-associated molecules
EP99942518A EP1108019A2 (en) 1998-08-27 1999-08-26 Protein transport-associated molecules
AU55877/99A AU5587799A (en) 1998-08-27 1999-08-26 Protein transport-associated molecules
US10/986,822 US20050130204A1 (en) 1998-08-27 2004-11-15 Protein-transport-associated molecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9820698P 1998-08-27 1998-08-27
US60/098,206 1998-08-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/986,822 Division US20050130204A1 (en) 1998-08-27 2004-11-15 Protein-transport-associated molecules

Publications (2)

Publication Number Publication Date
WO2000012703A2 WO2000012703A2 (en) 2000-03-09
WO2000012703A3 true WO2000012703A3 (en) 2000-06-22

Family

ID=22267998

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/019616 WO2000012703A2 (en) 1998-08-27 1999-08-26 Protein transport-associated molecules

Country Status (5)

Country Link
EP (1) EP1108019A2 (en)
JP (1) JP2002523089A (en)
AU (1) AU5587799A (en)
CA (1) CA2340794A1 (en)
WO (1) WO2000012703A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
WO2002002610A2 (en) * 2000-06-29 2002-01-10 Incyte Genomics, Inc. Secretion and trafficking molecules
JP2003259872A (en) * 2002-03-07 2003-09-16 Japan Science & Technology Corp Human esophageal carcinoma antigenic peptide and method for diagnosing esophageal carcinoma
KR20180002911A (en) 2005-11-04 2018-01-08 제넨테크, 인크. Use of complement pathway inhibitors to treat ocular diseases
US7776573B2 (en) 2006-06-01 2010-08-17 Genentech, Inc. Crystal structure of CRIg and C3b:CRIg complex
WO2008036135A2 (en) * 2006-06-01 2008-03-27 Genentech, Inc. Crystal structure of crig and c3b: crig complex
KR20160092061A (en) 2006-11-02 2016-08-03 제넨테크, 인크. Humanized anti-factor d antibodies
AR066660A1 (en) 2007-05-23 2009-09-02 Genentech Inc PREVENTION AND TREATMENT OF EYE CONDITIONS ASSOCIATED WITH THEIR COMPLEMENT
CR20170001A (en) 2008-04-28 2017-08-10 Genentech Inc ANTI FACTOR D HUMANIZED ANTIBODIES
RU2553517C2 (en) 2008-05-06 2015-06-20 Дженентек, Инк. Affinity-matured crig versions
CN107318267B (en) 2013-08-12 2021-08-17 豪夫迈·罗氏有限公司 Compositions and methods for treating complement-associated disorders
BR112016025312A2 (en) 2014-05-01 2017-10-17 Genentech Inc antibody variants, anti-d-factor antibody, pharmaceutical formulation, dispensing device, use of the formulation and a composition, composition and method of treating a disorder
CN108472382A (en) 2015-10-30 2018-08-31 豪夫迈·罗氏有限公司 Anti- factor D antibody variants conjugate and application thereof
JP2018534930A (en) 2015-10-30 2018-11-29 ジェネンテック， インコーポレイテッド Anti-factor D antibodies and conjugates

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002125427, Database accession no. AF044924 *
KAIN R ET AL: "Molecular cloning and expression of a novel human trans-Golgi network glycoprotein, TGN51, that contains multiple tyrosine-containing motifs", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 2, 9 January 1998 (1998-01-09), MD US, pages 981 - 988, XP002125426 *
PONNAMBALAM S ET AL.: "Primate homologues of rat TGN38: primary structure, expression and functional implications", JOURNAL OF CELL SCIENCE, vol. 109, no. 3, 1996, pages 675 - 685, XP000857634 *

Also Published As

Publication number Publication date
CA2340794A1 (en) 2000-03-09
WO2000012703A2 (en) 2000-03-09
AU5587799A (en) 2000-03-21
JP2002523089A (en) 2002-07-30
EP1108019A2 (en) 2001-06-20

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