WO1998008866B1 - Bau, une proteine interactive associee a la sequence bin1, et utilisations - Google Patents
Bau, une proteine interactive associee a la sequence bin1, et utilisationsInfo
- Publication number
- WO1998008866B1 WO1998008866B1 PCT/US1997/015298 US9715298W WO9808866B1 WO 1998008866 B1 WO1998008866 B1 WO 1998008866B1 US 9715298 W US9715298 W US 9715298W WO 9808866 B1 WO9808866 B1 WO 9808866B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- seq
- bau
- fragment
- antibody
- nucleotides
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title claims abstract 7
- 108090000623 proteins and genes Proteins 0.000 title claims abstract 7
- 108090001123 antibodies Proteins 0.000 claims abstract 10
- 102000004965 antibodies Human genes 0.000 claims abstract 10
- 229920001850 Nucleic acid sequence Polymers 0.000 claims abstract 7
- 229920001184 polypeptide Polymers 0.000 claims abstract 7
- 150000007523 nucleic acids Chemical group 0.000 claims abstract 6
- 229920002676 Complementary DNA Polymers 0.000 claims abstract 2
- 239000002299 complementary DNA Substances 0.000 claims abstract 2
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 150000001413 amino acids Chemical class 0.000 claims 6
- 230000003302 anti-idiotype Effects 0.000 claims 2
- 230000001809 detectable Effects 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims 1
- 230000001413 cellular Effects 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 108091006028 chimera Proteins 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 108010045030 monoclonal antibodies Proteins 0.000 claims 1
- 102000005614 monoclonal antibodies Human genes 0.000 claims 1
- 239000002751 oligonucleotide probe Substances 0.000 claims 1
- 108091008117 polyclonal antibodies Proteins 0.000 claims 1
- 230000001105 regulatory Effects 0.000 claims 1
- 206010053643 Neurodegenerative disease Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000002390 hyperplastic Effects 0.000 abstract 1
Abstract
Description d'un clone d'ADNc de la souris codant pour une protéine spécifique U1 associée à la séquence BIN1 (Bau). L'invention décrit aussi des procédés d'utilisation de séquences d'acide nucléique, de polypeptides et d'anticorps dirigés contre ledit clone dans le diagnostic et le traitement de certains cancers, d'états maladifs hyperplasiques ou de maladies dégénératives.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU41717/97A AU4171797A (en) | 1996-08-29 | 1997-08-28 | Bau, a bin1 interacting protein, and uses therefor |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2548296P | 1996-08-29 | 1996-08-29 | |
| US60/025,482 | 1996-08-29 | ||
| US08/919,145 US5958753A (en) | 1996-08-29 | 1997-08-27 | Nucleic acid sequences encoding Bau, a Bin1 interacting protein, and vectors and host cells containing same |
| US08/919,146 | 1997-08-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1998008866A1 WO1998008866A1 (fr) | 1998-03-05 |
| WO1998008866B1 true WO1998008866B1 (fr) | 1998-05-07 |
Family
ID=26699796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1997/015298 WO1998008866A1 (fr) | 1996-08-29 | 1997-08-28 | Bau, une proteine interactive associee a la sequence bin1, et utilisations |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US5958753A (fr) |
| AU (1) | AU4171797A (fr) |
| WO (1) | WO1998008866A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958753A (en) * | 1996-08-29 | 1999-09-28 | The Wistar Institute Of Anatomy And Biology | Nucleic acid sequences encoding Bau, a Bin1 interacting protein, and vectors and host cells containing same |
| EP0996857B1 (fr) * | 1997-07-17 | 2009-09-09 | Ludwig Institute For Cancer Research | Acides nucleiques et polypeptides associes au cancer |
| US6171790B1 (en) * | 1998-05-01 | 2001-01-09 | Incyte Pharmaceuticals, Inc. | Human protease associated proteins |
| CA2330187A1 (fr) * | 1998-06-04 | 1999-12-09 | Zymogenetics, Inc. | Polypeptides a noyau bisulfite |
| US6686147B1 (en) | 1998-07-15 | 2004-02-03 | Ludwig Institute For Cancer Research | Cancer associated antigens and uses therefor |
| AU7336700A (en) * | 1999-08-31 | 2001-03-26 | Wistar Institute Of Anatomy And Biology, The | Bridging integrator-2 (bin2) nucleic acid molecules and proteins and uses therefor |
| US6831063B1 (en) | 1999-08-31 | 2004-12-14 | The Wistar Institute Of Anatomy And Biology | Bridging Integrator-2(Bin2) nucleic acid molecules and proteins and uses therefor |
| US20030068624A1 (en) * | 2000-10-26 | 2003-04-10 | Recipon Herve E. | Compositions and methods relating to lung specific genes and proteins |
| US20030064378A1 (en) * | 2000-10-26 | 2003-04-03 | Recipon Herve E. | Compositions and methods relating to lung specific genes and proteins |
| US20030235821A1 (en) * | 2001-06-04 | 2003-12-25 | Zerhusen Bryan D. | Novel Human proteins, polynucleotides encoding them and methods of using the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3316601A1 (de) * | 1983-05-06 | 1984-11-08 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren zur immobilisierung von proteinen oder enzymen |
| US6048702A (en) * | 1995-05-05 | 2000-04-11 | The Wistar Institute Of Anatomy And Biology | Murine and human box-dependent myc-interacting protein (Bin1) and uses therefor |
| US5605830A (en) * | 1995-05-05 | 1997-02-25 | The Wistar Institute Of Anatomy & Biology | Murine and human c-Myc interacting protein |
| US5958753A (en) * | 1996-08-29 | 1999-09-28 | The Wistar Institute Of Anatomy And Biology | Nucleic acid sequences encoding Bau, a Bin1 interacting protein, and vectors and host cells containing same |
-
1997
- 1997-08-27 US US08/919,145 patent/US5958753A/en not_active Expired - Fee Related
- 1997-08-28 WO PCT/US1997/015298 patent/WO1998008866A1/fr active Application Filing
- 1997-08-28 AU AU41717/97A patent/AU4171797A/en not_active Abandoned
-
1999
- 1999-06-25 US US09/344,889 patent/US6140465A/en not_active Expired - Fee Related
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