WO1997005960A1 - Atomization apparatus and method utilizing surface acoustic waves - Google Patents
Atomization apparatus and method utilizing surface acoustic waves Download PDFInfo
- Publication number
- WO1997005960A1 WO1997005960A1 PCT/JP1996/002209 JP9602209W WO9705960A1 WO 1997005960 A1 WO1997005960 A1 WO 1997005960A1 JP 9602209 W JP9602209 W JP 9602209W WO 9705960 A1 WO9705960 A1 WO 9705960A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- liquid
- vibrator
- surface acoustic
- minute gap
- thin plate
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0676—Feeding means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
- Y02B30/00—Energy efficient heating, ventilation or air conditioning [HVAC]
- Y02B30/70—Efficient control or regulation technologies, e.g. for control of refrigerant flow, motor or heating
Definitions
- the present invention relates to a spray device and a spray method using surface acoustic waves, and more particularly to an ultrasonic spray device used for treating asthma, lung disease, and the like.
- FIG. 1 illustrates the spraying device described in this document.
- the spraying device includes a vibrator 3 having a pair of comb-shaped electrodes 5, 5 on its surface to generate surface acoustic waves, a cover 4 arranged on the vibrating surface of the vibrator 3, and a tube 1.
- the liquid 2 to be sprayed is supplied through the tube 1 as shown by the arrow A and into the gap between the oscillator 3 and the cover 4.
- the liquid 2 flowing out of the gap between the vibrator 3 and the cover 1 is atomized and sprayed by the surface acoustic wave vibration.
- the liquid supply amount and the spray amount vary.
- atomizing and atomizing the liquid only by the vibration of surface acoustic waves requires a large amount of electrical energy, and it is difficult to perform the desired operation by driving with a small-power dry cell. Disclosure of the invention
- An object of the present invention is to provide a spray device and a spray method capable of maintaining a good balance between a liquid supply amount and a spray amount and performing stable spraying.
- Another object of the present invention is to enable stable spraying even with a small amount of electric power such as a battery.
- Still another object of the present invention is to enable efficient atomization and spraying.
- a spray device includes a vibrator that generates a surface acoustic wave, a perforated thin plate having a large number of through-holes disposed on a vibration surface of the vibrator with a small gap therebetween, and a vibrator and a perforated thin plate. Means for supplying the liquid into the minute gap between. The liquid in the minute gap is atomized by surface acoustic wave vibration propagated by the vibrator, and is sprayed through the through-hole of the porous thin plate.
- the vibration due to the surface acoustic wave is generated in the minute gap. It is transmitted to the perforated thin plate via the liquid in the inside. Due to the vibration of the porous thin plate, a small amount of liquid that has permeated the through-hole is atomized and sprayed.
- the spraying device shown in Fig. 1 sprays the liquid on the vibrator by directly atomizing it by the vibration of surface acoustic waves, so large electric energy is required.
- the spraying method of the present invention it is possible to perform spraying by driving a battery with a small electric power of about 2 W of 1 Z 10 or less as compared with the apparatus shown in FIG.
- a porous thin plate has a large number of through holes.
- a ceramic made of a hard material which has a small amplitude attenuation due to vibration absorption is preferable. Ceramics have excellent corrosion resistance and have been confirmed to be safe for the human body. Therefore, for a nebulizer that sprays various chemicals used for asthma treatment, for example, a porous thin plate (mesh) made of ceramics is most suitable.
- the spraying device comprises a holder for holding both the oscillator and the perforated sheet with a small gap.
- the liquid supply means for supplying a liquid into the minute gap between the vibrator and the perforated thin plate includes a liquid container for storing a liquid to be atomized.
- the liquid in the liquid container is sucked into the minute gap by vibration due to surface acoustic waves or by capillary action.
- the surface elasticity continues to enter the minute gap. Since the liquid is automatically supplied by the vibration due to the wave and the capillary action due to z or surface tension, it is possible to maintain a good balance between the supply amount of the liquid and the spray amount.
- a means for forcibly sending the liquid into the minute gap is not particularly required, the size of the spray device can be reduced.
- the distance between the vibrator and the porous thin plate is preferably It is made to increase gradually as it approaches the liquid container.
- the vibrator has a propagation section through which the surface acoustic wave is to be propagated, and a non-propagation section through which the surface acoustic wave is not propagated.
- the micro-gap between the transducer and the perforated lamella extends over a propagating portion and a non-propagating portion.
- the small gap on the non-propagating part is immersed in the liquid in the liquid container in order to suck the liquid in the liquid container into the small gap due to the vibration caused by the surface acoustic wave and the no-capillarity.
- the liquid supply means of the spraying device comprises: a liquid container for storing the liquid to be atomized; and a liquid delivery means for forcibly sending the liquid in the liquid container into the minute gap as required.
- Liquid detecting means for detecting the presence or absence of liquid in the minute gap;
- Control means for controlling the operation of the liquid delivery means in response to these signals.
- the liquid is supplied into the minute gap according to the detection result of the presence or absence of the liquid in the minute gap, so that a good balance is maintained between the liquid supply amount and the spray amount. Can be.
- the liquid detecting means includes, for example, a first electrode and a second electrode arranged at intervals on the vibrating surface of the vibrator in the minute gap, and detects the presence or absence of the liquid by a change in capacitance between the two electrodes. .
- the spraying method includes a step of arranging a porous thin plate having a large number of through holes with a minute gap on a vibrating surface of a vibrator that generates a surface acoustic wave; and a step of guiding a liquid into the minute gap. And atomizing the liquid in the minute gap by surface acoustic wave vibration propagated by the vibrator, and spraying the liquid through the through holes of the porous thin plate.
- the liquid to be atomized is sucked into the minute gap from the liquid container storing the liquid by vibration due to surface acoustic waves or by capillary action.
- the liquid to be atomized is forcibly sent out of the liquid container storing the liquid into the minute gap by driving means.
- FIG. 1 is a perspective view showing a conventional atomizer using a vibrator that generates surface acoustic waves.
- FIG. 2 is an exploded perspective view of one embodiment according to the present invention.
- FIG. 3 is a perspective view of one embodiment of the present invention.
- FIG. 4 is a diagram for explaining a use state of one embodiment of the present invention.
- Fig. 5 shows an example of an inhaler incorporating a nebulizer.
- FIG. 6 is a perspective view showing a vibrator that generates surface acoustic waves.
- FIG. 7 is a perspective view showing another embodiment according to the present invention.
- FIG. 8 is a diagram for explaining a use state of the other embodiment.
- FIG. 9 is a perspective view showing a vibrator having a protruding non-propagating portion.
- FIG. 10 is a block diagram of yet another embodiment according to the present invention.
- FIG. 11 is an exploded perspective view of the spray device.
- FIG. 12 is a cross-sectional view showing a state in which a vibrator and a cap having a porous thin plate are combined.
- FIG. 13 is a sectional view showing a mechanism for supplying a liquid.
- the spraying device is provided with a vibrator 11 for generating a surface acoustic wave, a thin plate 12 having a mesh 12a at substantially the center, and a holder 13.
- the vibrator 11 has a rectangular substrate 14 made of, for example, lithium niobate (LiNb03), and a pair of comb-shaped electrodes 15 and 15 formed on the surface of the substrate 14. including.
- the comb-tooth portions 15a of the pair of comb-shaped electrodes 15 and 15 are arranged alternately along the longitudinal direction of the substrate 14.
- a high-frequency voltage is applied between a pair of comb electrodes 15 and 15
- a surface acoustic wave is generated. This surface acoustic wave propagates along the longitudinal direction of the vibrator 11.
- the substrate 14 of the vibrator 11 has positioning protrusions 14 a and 14 a on its side.
- the substantially square thin plate 12 includes a mesh 12a forming a large number of through holes. Each hole of the mesh 12a is set to a diameter sufficiently larger than the diameter of the spray particles generated by the vibration.
- ceramic As the material of the mesh 12a, ceramic is preferable. Ceramics do not absorb much of the vibration, so the amplitude is less attenuated. In addition, ceramics have excellent corrosion resistance and have been confirmed to be safe for the human body.
- the shape of the holder 13 is almost The shape is u-shaped, and the shape seen from above is almost rectangular.
- the holder 13 has a pair of side walls 13a, 13a, and grooves 16 and 17 are formed on the inner wall surfaces thereof.
- the groove 16 receives and holds the vibrator 11, and extends substantially parallel to the bottom wall 13 b of the holder 13.
- the groove 17 is for receiving and holding the thin plate 12 with a mesh. Since the groove 17 is formed at an angle to the bottom wall 13b of the holder 13, the distance between the groove 17 and the groove 16 is not constant.
- the distance between the two grooves is set to gradually increase toward the tip. As a dimensional example, for example, when the length of the groove 16 is 10 (1 O mm), the maximum distance between the groove 16 and the groove 17 at the tip is about 1 (1 mm) Is to be.
- the thin plate 12 with a mesh, and the holder 13 to make a spray device When assembling the vibrator 11, the thin plate 12 with a mesh, and the holder 13 to make a spray device, first move the tip of the substrate 14 of the vibrator 11 in the direction indicated by arrow A. Fit the holder 13 into the groove 16 of the holder. The movement of the vibrator 11 is performed until the positioning projection 14 a contacts the holder 13. Subsequently, the thin plate with mesh 12 is moved in the direction shown by the arrow B and is fitted into the groove 17 of the holder 13. Thus, the spray device shown in Fig. 3 is obtained. A minute gap is created between the vibrating surface of the vibrator held by the holder 13 and the thin plate 12 with a mesh. The distance between the vibrator 11 and the thin plate 12 is gradually increased toward the tip. Next, with reference to FIG. 4, the operation when the spraying device is used will be described.
- the liquid container 18 stores a liquid 19 to be sprayed.
- the tip of the vibrator 11 and the tip of the thin plate 12 with Z or mesh are immersed in the liquid in the liquid container 18. That is, the minute gap between the vibrator 11 and the thin plate 12 is immersed in the liquid.
- a surface acoustic wave is generated from the comb tooth portion 15 a of the vibrator 11, and the surface acoustic wave propagates on the vibrating surface of the vibrator 11.
- the liquid 19 is sucked into the minute gap between the vibrator 11 and the thin plate 12 by the vibration caused by the surface acoustic wave and the capillary action caused by the surface tension.
- the amount of liquid in the minute gap is small and appropriate, and can be sufficiently atomized by the vibration amplitude of the surface wave driven by low power.
- the vibration on the vibrating surface of the vibrator 11 is transmitted to the mesh 12 a of the thin plate 12 via the liquid in the minute gap. Due to the vibration of the mesh 12a, a small amount of liquid that has permeated the holes is atomized and sprayed.
- FIG. 5 is a cross-sectional view of an inhaler incorporating the nebulizer shown in FIGS.
- the inhaler includes a main body case 21 and a drug solution bottle 18.
- the main body case 21 has a circuit board 2 on which a circuit for driving the vibrator 11 1 is mounted in addition to a spraying device including the vibrator 11, a thin plate 12 with a mesh, and a holder 13. 3, battery 24 and power switch 25 are stored.
- Chemical liquid bottle 18 stores chemical liquid 19 when used, and Attached to the lower part of case 21. As shown in the figure, the lower ends of the vibrator 11 and the thin plate 12 with a mesh are immersed in the chemical solution 19.
- a small amount of liquid permeated into the holes of the mesh 12a of the thin plate 12 is atomized by the surface acoustic wave vibration and sprayed, it can be driven by a dry cell. Stable spraying can be performed.
- the liquid is supplied into the minute gap automatically by vibration and / or surface tension due to surface acoustic waves, there is no particular need for a means for forcibly sending the liquid. Therefore, a small spray device can be obtained. Further, since the liquid is supplied from the liquid container in accordance with the atomization, a good balance between the liquid supply amount and the spray amount can be maintained.
- the thin plate 12 with a mesh was used as the perforated thin plate having a large number of through holes
- the present invention is not limited to such a mesh, and a large number of through holes are formed in a flat thin plate. May be used.
- FIG. 6 illustrates a vibrator 30 having a pair of comb-shaped electrodes 31, 31.
- the surface acoustic wave generated by applying a voltage between the pair of comb electrodes 31 and 31 is represented by the comb teeth of the comb electrode.
- a hatched region 32 is a propagation portion through which surface acoustic waves are propagated
- the other region 33 is a non-propagation portion through which surface acoustic waves are not propagated.
- the surface acoustic wave is reflected by the end face of the vibrator 30 and interferes with the traveling wave to generate a standing wave, thereby increasing the vibration amplitude.
- the load of vibration increases, the surface acoustic wave diffuses in the liquid, and the increase in vibration amplitude due to the standing wave may not be expected. There is. In other words, if the portion of the vibrator 30 that is immersed in the liquid is on the propagation side of the surface acoustic wave, the power of the spray and the atomization efficiency may be reduced.
- the non-propagating portion of the oscillator 30 where the surface acoustic wave is not propagated is immersed in the liquid.
- the thin plate 34 having the mesh 34 a faces both the propagation part and the non-propagation part of the vibrator 30 to form a minute gap. I have.
- the distance between the vibrator 30 and the thin plate 34 with the mesh 34a is set to gradually increase as approaching the liquid container.
- FIG. 8 shows a state in which the non-propagating portion located on the side of the vibrator 30 and the tip of the thin plate 34 with a mesh are immersed in the liquid in the liquid container 35.
- the vibration load does not increase, No decrease in vibration amplitude occurs. Therefore, it is expected that the energy of the spray and the atomization efficiency will be improved.
- FIG. 9 illustrates another example of the oscillator 36 that generates a surface acoustic wave.
- the illustrated transducer 36 has a protruding portion 36a that bulges its outer edge in a region where surface acoustic waves do not propagate.
- the protrusion 36a is immersed in the liquid in the liquid container.
- the liquid is automatically supplied to the minute gap between the vibrator and the porous thin plate by vibration due to surface acoustic waves or by capillary action due to surface tension. Was to be done.
- the supply of the liquid to the minute gap is forcibly performed by the driving means. In this case, it is necessary to maintain a good balance between the supply amount of the liquid and the spray amount.
- the spraying device has a main body 51 that holds a vibrator 44 that generates a surface acoustic wave, and a mechanism that is attached to the main body 51 so as to receive the vibrator 44 inside. It is provided with a cap with a shroud 45 and a liquid bottle 46 for storing a liquid to be supplied on the vibrating surface of the vibrator 44.
- the cap 45 is held by the resilient force of the upper cap 45 a having an opening in the center, the lower cap 45 b, and the coil spring 50.
- the prepared mesh 48 is provided.
- a long hole 49 for receiving the projecting pipe 56 of the liquid bottle 46 is formed on a side wall of the lower cap 45b.
- the mesh (perforated thin plate) 48 and the diaphragm A minute gap is formed between the vibrating surface and the vibrating surface.
- the liquid in the liquid bottle 46 is supplied to the minute gap through the projecting pipe 56.
- FIG. 13 illustrates the configuration associated with the liquid bottle 46.
- the liquid bottle 46 stores the liquid 57 inside, and its upper space is closed.
- the high-pressure air sent out by the pressurized pump 47 housed in the main body 51 is introduced into the upper space of the liquid bottle 46 via the tube 53 and the check valve 54. Due to the introduction of the high-pressure air, the pressure in the liquid bottle 46 rises, and as a result, the liquid 57 in the liquid bottle 46 passes through the tube 55 and the projecting pipe 56 so that the vibrator 4 It is sent to the minute gap between 4 and mesh 48.
- the spraying device shown in FIGS. 10 to 13 includes a liquid detecting means for detecting the presence or absence of a liquid in a minute gap between the vibrator 44 and the mesh 48.
- a liquid detecting means for detecting the presence or absence of a liquid in a minute gap between the vibrator 44 and the mesh 48.
- two electrodes are arranged at an interval on the vibrating surface of the vibrator 44 in the minute gap.
- One electrode performs its function by the protruding pipe 56.
- the other electrode 60 protrudes from the main body 51.
- There is a gap between the protruding pipe 56 (first electrode) and the second electrode 60 There is a gap between the protruding pipe 56 (first electrode) and the second electrode 60, and the capacity between the two electrodes changes depending on the presence or absence of the liquid in this portion. The presence or absence of the liquid is detected based on the change in the capacity.
- the body 51 is provided with an electrode contact 59.
- the liquid bottle 46 also has an electrode contact 58 in contact with
- the material of the mesh 48 which is a porous thin plate, is optimally ceramic. Depending on the size of the mesh holes, the amount of atomization may vary. Even if there is such a variation in the amount of atomization, it is desirable to perform continuous and stable spraying. Therefore, in the embodiment shown in FIGS. 10 to 13, liquid detecting means for detecting the presence or absence of liquid in the minute gap is provided, and the liquid bottle 46 is provided in response to a signal from the liquid detecting means. Liquid is forcibly sent into the minute gap.
- the spraying device includes a dry battery 40, a power supply circuit 41, a control circuit 42, an oscillation circuit 43, a pressurizing pump 47, and a liquid pump.
- a bottle 46 is provided. The operation is performed as follows.
- the pressurizing pump 47 When an appropriate amount of liquid exists in the minute gap between the vibrator 44 and the mesh 48, the pressurizing pump 47 is not driven. On the other hand, when the liquid in the minute gap is exhausted, the capacity between the first electrode 56 and the second electrode 60 changes, and it is detected that there is no liquid.
- the control circuit 42 drives the pressurizing pump 47 in response to the detection signal.
- the high-pressure air sent from the pressurizing pump 47 is introduced into the liquid bottle 46, and as a result, the liquid in the liquid bottle 46 passes through the tube 55 and the protruding pipe 56 to the vibrator 44 and the female. It is sent out into the minute gap with the brush 48.
- the vibration of the surface acoustic wave propagating on the vibrating surface of the vibrator 4 meshes through the liquid in the minute gap.
- a small amount of liquid that has been transmitted to the mesh 48 and penetrated into the holes of the mesh 48 is atomized and sprayed to the outside. By repeating this operation, a good balance between the supply amount of the liquid and the spray amount is maintained.
- the high-pressure air is introduced into the liquid bottle 46 to send out the liquid, the liquid in the liquid bottle 46 can be sufficiently consumed.
- the pressurizing pump 47 is not driven, so that the supply of the liquid to the minute gap is performed intermittently.
- the electrode sensors 56 and 60 for detecting water must be periodically attached and detached and washed to prevent malfunction.
- the protruding pipe 56 is also used as one of the electrode sensors.
- the present invention can be advantageously applied to an inhaler or the like which sprays a medicinal solution effective for treating asthma and lung disease.
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- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
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Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50831897A JP3341023B2 (ja) | 1995-08-07 | 1996-08-05 | 表面弾性波を利用した噴霧装置および噴霧方法 |
US09/000,299 US5996903A (en) | 1995-08-07 | 1996-08-05 | Atomizer and atomizing method utilizing surface acoustic wave |
EP96926005A EP0844027B1 (en) | 1995-08-07 | 1996-08-05 | Atomization apparatus and method utilizing surface acoustic waves |
DE69635206T DE69635206T2 (de) | 1995-08-07 | 1996-08-05 | Zerstäubungsvorrichtung und verfahren die akustische oberflächenwellen anwenden |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7/200769 | 1995-08-07 | ||
JP20076995 | 1995-08-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997005960A1 true WO1997005960A1 (en) | 1997-02-20 |
Family
ID=16429875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1996/002209 WO1997005960A1 (en) | 1995-08-07 | 1996-08-05 | Atomization apparatus and method utilizing surface acoustic waves |
Country Status (6)
Country | Link |
---|---|
US (1) | US5996903A (ja) |
EP (2) | EP1602414B1 (ja) |
JP (1) | JP3341023B2 (ja) |
KR (1) | KR100268533B1 (ja) |
DE (2) | DE69637458T2 (ja) |
WO (1) | WO1997005960A1 (ja) |
Cited By (19)
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WO1999017888A1 (fr) | 1997-10-06 | 1999-04-15 | Omron Corporation | Pulverisateur |
JP2005111471A (ja) * | 2003-09-16 | 2005-04-28 | Igaku Seibutsugaku Kenkyusho:Kk | 弾性表面波を利用した加熱装置 |
JP2008104966A (ja) * | 2006-10-26 | 2008-05-08 | Seiko Epson Corp | 霧化装置、吸引装置 |
JP2008173624A (ja) * | 2006-12-18 | 2008-07-31 | Tamura Seisakusho Co Ltd | 霧化装置 |
JP2008229455A (ja) * | 2007-03-19 | 2008-10-02 | Tamura Seisakusho Co Ltd | 霧化装置 |
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JP2010088917A (ja) * | 2002-01-18 | 2010-04-22 | Respironics Respiratory Drug Delivery (Uk) Ltd | 噴霧器計量室 |
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US7045934B2 (en) * | 2002-04-11 | 2006-05-16 | Ernest Geskin | Method for jet formation and the apparatus for the same |
US6752327B2 (en) | 2002-10-16 | 2004-06-22 | S. C. Johnson & Son, Inc. | Atomizer with tilted orifice plate and replacement reservoir for same |
US8012136B2 (en) | 2003-05-20 | 2011-09-06 | Optimyst Systems, Inc. | Ophthalmic fluid delivery device and method of operation |
DE102004011726A1 (de) * | 2004-03-05 | 2005-09-22 | Ing. Erich Pfeiffer Gmbh | Dosiervorrichtung |
MXPA06011426A (es) * | 2004-04-02 | 2007-04-20 | Gov Health & Human Serv | Sistemas y metodos de suministro en aerosol. |
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US6273342B1 (en) | 1997-10-06 | 2001-08-14 | Omron Corporation | Atomizer |
WO1999017888A1 (fr) | 1997-10-06 | 1999-04-15 | Omron Corporation | Pulverisateur |
JP2010088917A (ja) * | 2002-01-18 | 2010-04-22 | Respironics Respiratory Drug Delivery (Uk) Ltd | 噴霧器計量室 |
US8936021B2 (en) | 2003-05-20 | 2015-01-20 | Optimyst Systems, Inc. | Ophthalmic fluid delivery system |
JP2005111471A (ja) * | 2003-09-16 | 2005-04-28 | Igaku Seibutsugaku Kenkyusho:Kk | 弾性表面波を利用した加熱装置 |
JP4507239B2 (ja) * | 2003-09-16 | 2010-07-21 | 祥子 塩川 | 弾性表面波を利用した加熱装置 |
JP2008104966A (ja) * | 2006-10-26 | 2008-05-08 | Seiko Epson Corp | 霧化装置、吸引装置 |
JP2008173624A (ja) * | 2006-12-18 | 2008-07-31 | Tamura Seisakusho Co Ltd | 霧化装置 |
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JP2008253926A (ja) * | 2007-04-05 | 2008-10-23 | Tamura Seisakusho Co Ltd | 霧化装置 |
WO2010047110A1 (ja) * | 2008-10-24 | 2010-04-29 | パナソニック電工株式会社 | 弾性表面波霧化装置 |
JP5154658B2 (ja) * | 2008-10-24 | 2013-02-27 | パナソニック株式会社 | 弾性表面波霧化装置 |
US8480010B2 (en) | 2008-10-24 | 2013-07-09 | Panasonic Corporation | Surface acoustic wave atomizer |
JP2011089693A (ja) * | 2009-10-22 | 2011-05-06 | Panasonic Corp | 加湿装置 |
US10839960B2 (en) | 2010-07-15 | 2020-11-17 | Eyenovia, Inc. | Ophthalmic drug delivery |
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US8684980B2 (en) | 2010-07-15 | 2014-04-01 | Corinthian Ophthalmic, Inc. | Drop generating device |
US9087145B2 (en) | 2010-07-15 | 2015-07-21 | Eyenovia, Inc. | Ophthalmic drug delivery |
US10073949B2 (en) | 2010-07-15 | 2018-09-11 | Eyenovia, Inc. | Ophthalmic drug delivery |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
US11839487B2 (en) | 2010-07-15 | 2023-12-12 | Eyenovia, Inc. | Ophthalmic drug delivery |
US11398306B2 (en) | 2010-07-15 | 2022-07-26 | Eyenovia, Inc. | Ophthalmic drug delivery |
US8733935B2 (en) | 2010-07-15 | 2014-05-27 | Corinthian Ophthalmic, Inc. | Method and system for performing remote treatment and monitoring |
JP2012055361A (ja) * | 2010-09-06 | 2012-03-22 | Ceramics Craft Co Ltd | 噴霧機構付き加熱調理器 |
US10639194B2 (en) | 2011-12-12 | 2020-05-05 | Eyenovia, Inc. | High modulus polymeric ejector mechanism, ejector device, and methods of use |
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US11938056B2 (en) | 2017-06-10 | 2024-03-26 | Eyenovia, Inc. | Methods and devices for handling a fluid and delivering the fluid to the eye |
WO2019198162A1 (ja) * | 2018-04-10 | 2019-10-17 | 日本たばこ産業株式会社 | 霧化ユニット |
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JP7336663B2 (ja) | 2019-07-05 | 2023-09-01 | パナソニックIpマネジメント株式会社 | 液体霧化システム及びミスト発生システム |
Also Published As
Publication number | Publication date |
---|---|
US5996903A (en) | 1999-12-07 |
EP0844027B1 (en) | 2005-09-21 |
EP1602414B1 (en) | 2008-03-05 |
EP0844027A1 (en) | 1998-05-27 |
KR100268533B1 (ko) | 2000-10-16 |
DE69637458T2 (de) | 2009-03-05 |
KR19990036166A (ko) | 1999-05-25 |
DE69635206D1 (de) | 2006-02-02 |
EP0844027A4 (en) | 2001-06-13 |
DE69637458D1 (de) | 2008-04-17 |
JP3341023B2 (ja) | 2002-11-05 |
EP1602414A2 (en) | 2005-12-07 |
DE69635206T2 (de) | 2006-06-22 |
EP1602414A3 (en) | 2006-05-31 |
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