UY28271A1 - Compuestos químicos - Google Patents

Compuestos químicos

Info

Publication number
UY28271A1
UY28271A1 UY28271A UY28271A UY28271A1 UY 28271 A1 UY28271 A1 UY 28271A1 UY 28271 A UY28271 A UY 28271A UY 28271 A UY28271 A UY 28271A UY 28271 A1 UY28271 A1 UY 28271A1
Authority
UY
Uruguay
Prior art keywords
chemical compounds
treatment
proliferative diseases
medicaments
cancer
Prior art date
Application number
UY28271A
Other languages
English (en)
Inventor
Pasquet Georges Rene
Heron Nicola Murdoch
Mortlock Andrew Austen
Jung Frederic Henri
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY28271A1 publication Critical patent/UY28271A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Derivados de quinazolina de fórmula (i) para su utilización en el tratamiento de enfermedades proliferativas tales como el cáncer y en la preparación de medicamentos para su utilización en el tratamiento de enfermedades proliferativas y procediemientos de preparación de los mismos, así como composiciones farmacéuticas que los contienen como ingredientes activo.
UY28271A 2003-04-16 2004-04-16 Compuestos químicos UY28271A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03290951 2003-04-16

Publications (1)

Publication Number Publication Date
UY28271A1 true UY28271A1 (es) 2004-11-30

Family

ID=33305809

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28271A UY28271A1 (es) 2003-04-16 2004-04-16 Compuestos químicos

Country Status (23)

Country Link
US (1) US7691867B2 (es)
EP (1) EP1613619B1 (es)
JP (1) JP4709139B2 (es)
KR (1) KR20060003351A (es)
CN (1) CN1809557B (es)
AR (1) AR043875A1 (es)
AT (1) ATE390422T1 (es)
AU (1) AU2004232527A1 (es)
BR (1) BRPI0409427A (es)
CA (1) CA2522079A1 (es)
CL (1) CL2004000797A1 (es)
CO (1) CO5640037A2 (es)
DE (1) DE602004012725T2 (es)
ES (1) ES2301981T3 (es)
HK (1) HK1086573A1 (es)
IS (1) IS8125A (es)
MX (1) MXPA05011076A (es)
NO (1) NO20054842L (es)
RU (1) RU2005135337A (es)
TW (1) TW200510392A (es)
UY (1) UY28271A1 (es)
WO (1) WO2004094410A1 (es)
ZA (1) ZA200508372B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04006260A (es) * 2001-12-24 2005-03-31 Astrazeneca Ab Derivados de quinazolina sustituidos como inhibidores de cinasas aurora.
ATE438644T1 (de) * 2002-12-24 2009-08-15 Astrazeneca Ab Chinazolinderivate
DE602004015108D1 (de) * 2003-06-02 2008-08-28 Astrazeneca Ab (3-((chinazolin-4-yl)amino)-1h-pyrazol-1-yl)acetamid derivate und verwandte verbindungen als aurora kinase inhibitoren zur behandlung von proliferativen erkrankungen wie krebs
JP4205757B2 (ja) 2004-05-06 2009-01-07 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー ４−フェニルアミノ−キナゾリン−６−イル−アミド
US20090036485A1 (en) * 2004-10-12 2009-02-05 Frederic Henri Jung Quinoline derivatives
US20090036474A1 (en) * 2004-10-12 2009-02-05 Patrick Ple Quinazoline derivatives for use against cancer
NZ554017A (en) 2004-10-12 2010-06-25 Astrazeneca Ab [(Quinazolin-4-yloxy)phenyl]acetamide derivatives
WO2006044687A2 (en) 2004-10-15 2006-04-27 Takeda San Diego, Inc. Kinase inhibitors
BRPI0517734A (pt) * 2004-11-17 2008-10-21 Korea Res Inst Chem Tech derivados de 1-[(6,7-alcoxiquinoxalinil substituìdo) aminocarbonil]-4- (hetero) arilpiperazina
GB0510963D0 (en) * 2005-05-28 2005-07-06 Astrazeneca Ab Chemical compounds
EP1888572A1 (en) * 2005-05-28 2008-02-20 AstraZeneca AB Quinazolines and their use as aurora kinase inhibitors
JP2009508922A (ja) * 2005-09-22 2009-03-05 アストラゼネカ アクチボラグ ４−アミノピラゾール誘導体の製造方法
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
GB0601215D0 (en) * 2006-01-21 2006-03-01 Astrazeneca Ab Chemical compounds
UY30183A1 (es) 2006-03-02 2007-10-31 Astrazeneca Ab Derivados de quinolina
JP2009528335A (ja) * 2006-03-02 2009-08-06 アストラゼネカ アクチボラグ キナゾリン誘導体
WO2007113565A1 (en) * 2006-04-06 2007-10-11 Astrazeneca Ab Naphthyridine derivatives as anti-cancer agents
GB0609617D0 (en) 2006-05-16 2006-06-21 Astrazeneca Ab Process & intermediate
GEP20135728B (en) 2006-10-09 2013-01-25 Takeda Pharmaceuticals Co Kinase inhibitors
FR2908409B1 (fr) 2006-11-10 2009-01-09 Sanofi Aventis Sa Pyrazoles substituees,compositions les contenant,procede de fabrication et utilisation
TWI577671B (zh) * 2011-11-14 2017-04-11 Sunshine Lake Pharma Co Ltd Aminoquinazoline derivatives and salts thereof and methods of use thereof
CN103012428A (zh) 2013-01-08 2013-04-03 中国药科大学 4-(五元杂环并嘧啶/吡啶取代)氨基-1H-3-吡唑甲酰胺类CDK/Aurora双重抑制剂及其用途
CN104098551B (zh) * 2013-04-03 2019-03-22 广东东阳光药业有限公司 作为欧若拉激酶抑制剂的取代喹唑啉类衍生物
CN103382158B (zh) * 2013-07-29 2015-11-18 张家港市大伟助剂有限公司 一种2-环戊基氨基乙醇的制备方法
KR20160060071A (ko) * 2013-09-19 2016-05-27 피에르 파브르 메디카먼트 퀴나졸린 유도체 및 ｄｎａ 메틸전이효소 저해제들로의 용도

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710158A (en) 1991-05-10 1998-01-20 Rhone-Poulenc Rorer Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
TW321649B (es) * 1994-11-12 1997-12-01 Zeneca Ltd
WO1997017329A1 (fr) * 1995-11-07 1997-05-15 Kirin Beer Kabushiki Kaisha Derives de quinoline et derives de quinazoline inhibant l'autophosphorylation d'un recepteur de facteur de croissance originaire de plaquettes, et compositions pharmaceutiques les contenant
ES2334879T3 (es) * 1999-09-21 2010-03-17 Astrazeneca Ab Derivados de quinazolina y su uso como productos farmaceuticos.
GB9922171D0 (en) 1999-09-21 1999-11-17 Zeneca Ltd Chemical compounds
DE60133897D1 (de) 2000-06-28 2008-06-19 Astrazeneca Ab Substituierte chinazolin-derivate und deren verwendung als aurora-2-kinase inhibitoren
MXPA04006260A (es) * 2001-12-24 2005-03-31 Astrazeneca Ab Derivados de quinazolina sustituidos como inhibidores de cinasas aurora.
EP1548008A4 (en) * 2002-08-23 2008-08-06 Kirin Pharma Kk COMPOUND HAVING BETA-TRANSFORMING GROWTH FACTOR INHIBITORY ACTIVITY AND DRUG CONTAINING COMPOSITION
AU2003290322A1 (en) * 2002-12-24 2004-07-22 Astrazeneca Ab Quinazoline compounds
ATE438644T1 (de) * 2002-12-24 2009-08-15 Astrazeneca Ab Chinazolinderivate
AU2003294142A1 (en) 2002-12-24 2004-07-22 Astrazeneca Ab Therapeutic quinazoline derivatives
DE602004015108D1 (de) * 2003-06-02 2008-08-28 Astrazeneca Ab (3-((chinazolin-4-yl)amino)-1h-pyrazol-1-yl)acetamid derivate und verwandte verbindungen als aurora kinase inhibitoren zur behandlung von proliferativen erkrankungen wie krebs
TW200505452A (en) * 2003-06-17 2005-02-16 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
KR20060003351A (ko) 2006-01-10
NO20054842L (no) 2005-11-08
CL2004000797A1 (es) 2005-05-27
CO5640037A2 (es) 2006-05-31
JP4709139B2 (ja) 2011-06-22
MXPA05011076A (es) 2006-01-24
HK1086573A1 (en) 2006-09-22
TW200510392A (en) 2005-03-16
CN1809557B (zh) 2012-07-04
ATE390422T1 (de) 2008-04-15
DE602004012725D1 (de) 2008-05-08
BRPI0409427A (pt) 2006-04-18
ES2301981T3 (es) 2008-07-01
US7691867B2 (en) 2010-04-06
AR043875A1 (es) 2005-08-17
JP2006523660A (ja) 2006-10-19
DE602004012725T2 (de) 2009-04-16
CA2522079A1 (en) 2004-11-04
CN1809557A (zh) 2006-07-26
EP1613619A1 (en) 2006-01-11
AU2004232527A1 (en) 2004-11-04
EP1613619B1 (en) 2008-03-26
IS8125A (is) 2005-11-11
WO2004094410A1 (en) 2004-11-04
RU2005135337A (ru) 2006-06-10
US20060270692A1 (en) 2006-11-30
ZA200508372B (en) 2007-04-25

Similar Documents

Publication Publication Date Title
UY28271A1 (es) Compuestos químicos
UY28366A1 (es) Compuestos químicos
ECSP109935A (es) Derivados de morfolino pirimidina utilizados en enfermedades relacionadas con mtor quinasa y/o pi3k
UY29562A1 (es) Compuestos heterocíclicos de amino benzoilo, composiciones farmacéuticas que los contienen, procedimientos de preparación y aplicaciones
UY30759A1 (es) Compuestos quimicos
UY28510A1 (es) Compuestos quimicos
AR047928A1 (es) Derivados de tetrahidropiridoindol
CO6390066A2 (es) Derivados de pirimidina trisustituida para el tratamiento de enfermedades proliferativas
UY29781A1 (es) Compuestos diazaspiro sustituidos, sales farmacéuticamente aceptables, composiciones farmacéuticas que contienen los compuestos o sales, métodos de preparación y usos
ECSP109934A (es) Compuesto - 946
UY30559A1 (es) Derivados de morfolino pirimidina, procesos de preparacion, composiciones conteniéndolos y aplicaciones
DOP2010000390A (es) Compuestos de piridina
UY29087A1 (es) Derivados de adamantilo, composiciones farmaceuticas que los contienen, procesos para su preparacion y uso terapeutico
CR11641A (es) Derivados heterociclicos de urea y metodos de uso de los mismos-211
ECSP105253A (es) Derivados de 5-feniltiazol y uso como inhibidores de pi3 cinasa
UY30282A1 (es) Compuestos quimicos
UY29767A1 (es) Derivados de benzotiazolonas, procesos para su preparación, composiciones farmacéuticas que los contienen y aplicaciones
UY29003A1 (es) Nuevos derivados de hidantoína, procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en terapia
UY31141A1 (es) Compuestos de piperidina y sus usos
DOP2010000374A (es) Derivados heterociclicos de la urea y sus metodos de empleo
CO6382176A2 (es) Derivados de urea heterociclicos y metodos de uso de los mismos-332
UY28356A1 (es) Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usos
UY28357A1 (es) Derivados de benzimidazol, composiciones que los contienen, preparación de los mismos y sus usos
UY29561A1 (es) Derivados de quinazolina, composiciones farmacéuticas que los contienen, procedimientos de preparación y aplicaciones
TW200634002A (en) Chemical compounds

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20150521