UY26943A1 - Derivados de piridina - Google Patents

Derivados de piridina

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Publication number
UY26943A1
UY26943A1 UY26943A UY26943A UY26943A1 UY 26943 A1 UY26943 A1 UY 26943A1 UY 26943 A UY26943 A UY 26943A UY 26943 A UY26943 A UY 26943A UY 26943 A1 UY26943 A1 UY 26943A1
Authority
UY
Uruguay
Prior art keywords
amino
alkyl
hydrogen
halogen
alkoxy
Prior art date
Application number
UY26943A
Other languages
English (en)
Inventor
Hiroshi Kadono
Toshiki Murata
Sachiko Sakakibara
Takashi Yoshino
Hiroki Sato
Masaomi Umeda
Tsutomu Masuda
Yuji Koriyama
Mitsuyuki Shimada
Takuya Shintani
Timothy B Lowinger
Karl B Ziegelbauer
Kinji Fuchikami
Hiroshi Komura
Original Assignee
Bayer Ag
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Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of UY26943A1 publication Critical patent/UY26943A1/es

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/08—Preparation by ring-closure
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Los compuestos de pirimida de fórmula general (I), en la que R1 representa (II), en la que R11 es hidrógeno, alquilo C 1-6, halógeno, alcoxi C1-12 nitro, amino, alquil C1-6 sulfonilamino, alcoxi C1-6-carbonilo, alquil C1-6-amino, di (alquil C1-6) amino, alcanil C1-6-amino, fenilalquil C1-6- amino, fenilsulfonilamino o -O- (CH2)n-R111,R2 representa hidrógeno o halógeno; R3 representa hidrógeno- CR31 R32 R33, o NR34 R35; R4 es hidrógeno, carbamoilo, CN, carboxilo, etc; R5 es amino, alquilamino C1-6, di(alquil C1-6)amino, etc. O una sal del mismo. El compuesto presenta una actividad antiinflamatoria excelente y otras actividades biológicas.
UY26943A 2000-09-22 2001-09-20 Derivados de piridina UY26943A1 (es)

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AU2001289873A1 (en) 2002-04-02
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