US4592353A - Medical and surgical laser probe - Google Patents
Medical and surgical laser probe Download PDFInfo
- Publication number
- US4592353A US4592353A US06/612,674 US61267484A US4592353A US 4592353 A US4592353 A US 4592353A US 61267484 A US61267484 A US 61267484A US 4592353 A US4592353 A US 4592353A
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- US
- United States
- Prior art keywords
- laser
- probe
- transmissive material
- optical fiber
- medical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/24—Coupling light guides
- G02B6/42—Coupling light guides with opto-electronic elements
- G02B6/4296—Coupling light guides with opto-electronic elements coupling with sources of high radiant energy, e.g. high power lasers, high temperature light sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- B23K26/00—Working by laser beam, e.g. welding, cutting or boring
- B23K26/02—Positioning or observing the workpiece, e.g. with respect to the point of impact; Aligning, aiming or focusing the laser beam
- B23K26/06—Shaping the laser beam, e.g. by masks or multi-focusing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- B23K26/00—Working by laser beam, e.g. welding, cutting or boring
- B23K26/02—Positioning or observing the workpiece, e.g. with respect to the point of impact; Aligning, aiming or focusing the laser beam
- B23K26/06—Shaping the laser beam, e.g. by masks or multi-focusing
- B23K26/064—Shaping the laser beam, e.g. by masks or multi-focusing by means of optical elements, e.g. lenses, mirrors or prisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- B23K26/00—Working by laser beam, e.g. welding, cutting or boring
- B23K26/02—Positioning or observing the workpiece, e.g. with respect to the point of impact; Aligning, aiming or focusing the laser beam
- B23K26/06—Shaping the laser beam, e.g. by masks or multi-focusing
- B23K26/064—Shaping the laser beam, e.g. by masks or multi-focusing by means of optical elements, e.g. lenses, mirrors or prisms
- B23K26/0648—Shaping the laser beam, e.g. by masks or multi-focusing by means of optical elements, e.g. lenses, mirrors or prisms comprising lenses
Definitions
- This invention relates to a medical and surgical laser probe, and more particularly to a medical and surgical laser probe having, at a forward end thereof, a contact member made of a laser transmitting material so as to allow the probe to be used in contact with the tissue which is to be subjected to laser irradiation treatment.
- a non-contact type laser irradiation probe made of an optical fiber for carrying out incision and coagulation of the tissue for a living organ through irradiation of laser beam emitted from the optical fiber.
- This type of laser probe makes incision or coagulation by irradiating laser beam such as Nd:YAG laser, Argon laser, etc. from the forward end of a laser beam guide of an optical fiber such as an elongated quartz core which is optically connected to a laser source.
- Such a non-contact type laser irradiation probe is used in such a manner that it is kept a distance from the tissue so as not to contact the tissue for preventing possible burning of the laser emitting end of the optical fiber.
- This type of laser probe has no fatal problem and therefore desired effect can be obtained if the laser output is kept constant and the distance from the tissue is kept constant during the laser irradiation.
- it is quite difficult to keep the distance constant from the tissue because the living tissue moves by itself and it is also difficult for the operator to keep the distance constant by a free hand. Therefore, the effect of laser irradiation onto the tissue cannot be constant or uniform and a serious result is possibly caused onto the patient. This problem is most noticeable when the laser probe is used for laser irradiation treatment through endoscope.
- the conventional laser probe has another problem that the divergency angle of laser beam which is emitted from the tip end of the optical fiber into air is as small as 7° to 10° and therefore the irradiation must be repeated to cover the entire area to be irradiated by laser beam and a considerable time is required to complete the irradiation.
- the probe has a further problem that since the laser is once emitted into air and onto the tissue, 30 to 40% of the emitted laser beam, in general, is backscattered from the surface of the tissue and a serious energy loss is caused.
- a gas is fed through a space between a sheath tube covering optical fiber and an outer tube covering the sheath tube and discharged outside of the probe to effect cooling of the laser emitting end of the fiber and expelling of blood and mucus.
- This also involves such a serious problem that a considerable amount of gas is needed to acquire a sufficient cooling effect because a gas generally has rather low cooling ability.
- the conventional laser probe of this type is used for irradiation onto an inner wall of stomach, the stomach is filled with a gas and swollen by the gas. This not only gives the patient unpleasantness but sometimes causes perforation in the stomach wall because laser is irradiated on the swollen and thinned stomach wall.
- FIGS. 9 and 10 The typical structure of the conventional laser probe suited for hemostasis will now be described referring to FIGS. 9 and 10.
- the 100 designates an optical fiber made for example of quartz covered by sheath 102.
- the fiber 100 is optically connected to a laser source.
- An outer tube 106 is coaxially provided around the sheath tube 102 keeping a gap 104 therefrom.
- An annular tip member 108 is disposed at the forward end of the tube 102 so that the laser emitting end of the optical fiber 100 may not directly contact the tissue.
- the outer tube 106 is fitted around a stepped portion of the tip member 108 so that the assembly has a smooth or flush surface.
- the stepped portion of the tip member 108 has two slits 110.
- laser beam irradiation is carried out keeping the probe distanced from the tissue and feeding a gas G through the gap 104 between the sheath tube 102 and the outer tube 106.
- the gas is guided into the tip member 108 through the slits 110 and discharged from the opening of the forward end of the tip member 108.
- This conventional laser probe cannot enlarge the divergency angle determined by the characteristics of the optical fiber 100 itself.
- the tip member 108 is provided and a gas is jetted to prevent blood etc. from entering the laser emitting end of the optical fiber 100 for protection of the probe, this cannot be prevented completely and the treatment is interrupted and serious result is caused when blood or mucus from the tissue enter the emitting end.
- a medical and surgical laser probe including an optical fiber connected optically to a laser source for emitting laser beam, which comprises a contact member of a laser transmitting material disposed in front of the optical fiber and adapted to be used in contact with the tissue to be irradiated by laser beam, said contact member allowing the laser beam to be transmitted therethrough without causing substantial convergency.
- a medical and surgical laser probe including an optical fiber optically connected to a laser source, a sheath tube covering the fiber, an outer tube coaxially disposed around the sheath tube keeping a gap therefrom and a fluid introducing member provided at a base portion of the probe for letting a fluid pass through the gap,
- which probe comprises a hollow and cylindrical holder fitted around the forward portion of the sheath tube and engaged with the outer tube to receive the forward end portion thereof; and a contact member made of a laser transmitting material and disposed in front of the forward end of the optical fiber so as to be used in contact with the tissue to be irradiated by laser beam, allowing the laser beam to transmit therethrough without causing any substantial convergency, said contact member being fixed to the holder.
- None of the conventional probes are of contact type.
- This type of probe is specialized for the incision but not suited for effecting coagulation, and it is also of a non-contact type and cannot be free from the disadvantages involved in the non-contact type probe.
- the irradiation effect is not varied by the movement of the living tissue.
- the operating efficiency is highly improved. This effect is especially noticeable in the endoscopic irradiation.
- the contact member at the forward end of the optical fiber, it is prevented that blood or mucus enters the laser emitting end of the optical fiber.
- burning of the emitting end of the optical fiber can be prevented and possible interruption of medical treatment by irradiation can be avoided.
- the conventional laser probe it is necessary that blood or mucus be expelled from the emitting end of the optical fiber as well as the emitting end be cooled by feeding a gas.
- the penetration of blood etc. into the emitting end can be prevented and therefore it suffices to cool the emitting end of the optical fiber which generates a heat due to scattered laser beam. Therefore, only small amount of cooling fluid such as watercan attain the purpose.
- the cooling water is supplied dropwise from the forward end of the probe.
- the probe of the present invention can also be suitably applied to an organ where any type of gas cannot be used. It is, however, to be noted that a gas may also be used in the present invention as the case may be.
- the divergency angle of the optical fiber is determined as 7° to 10° as described above. If the diameter of the laser beam irradiation is small as in the conventional case, the area to be irradiated must be divided and irradiation must be repeated to complete irradiation of the entire area. Thus, it takes a considerable time to complete irradiation. For example, when a vein is required to be closed, such a procedure is necessitated that irradiation is repeated around a blooding opening of the vein so as to effect hemostasis and thereafter the blooding opening is coagulated.
- the contact member has a back formed in a concaved curved face to enlarge the divergency angle and allow the laser beam to be irradiated at an increased divergency angle.
- treatment of a wider area can be accomplished by one irradiation.
- the contact member when the vein is required to be closed as mentioned above, it substantially suffices to make irradiation with the contact member being directly pressed against the blooding opening of the vein to accomplish hemostasis.
- FIG. 1 is an explanatory view of a laser irradiation system according to the present invention
- FIG. 2 is a sectional side view of a laser probe according to the present invention.
- FIG. 3 is a perspective view of the forward end portion of the laser probe of FIG. 2;
- FIG. 4 is an explanatory sectional view showing the configuration of the peripheral portion of the forward end of the contact member
- FIG. 5 is an explanatory view showing the peripheral portion of the forward end of the contact member formed in an angular configuration
- FIG. 6 is an explanatory sectional view showing the expelling of blood being coagulated along the peripheral portion of the forward end of the contact member formed in a rounded configuration
- FIG. 7 is an explanatory sectional view of another form of contact member
- FIG. 8 is an explanatory view showing the dimensions of the laser probe employed in example.
- FIG. 9 is a sectional view of the forward end of the conventional non-contact type laser probe.
- FIG. 10 is a cross sectional view along line X--X of FIG. 9.
- FIG. 1 is a schematic view of the entire system of the laser irradiation apparatus according to the present invention and FIG. 2 is a sectional view of the detail of a laser probe of the present invention.
- Numeral 2 designates an optical fiber made of for example glass or quartz, preferably quartz.
- the fiber is covered by sheath tube 4 made for example of Teflon (a trade mark of polymer of tetrafluoroethylene manufactured and sold by du Pont).
- the optical fiber 2 is optically connected to a known laser source 6.
- Numeral 8 is an outer tube made for example of Teflon and disposed coaxially around the tube 4 keeping a gap 10 therefrom.
- a T-shaped adaptor 12 of a metallic material is provided at the base portion of the outer tube 8 for letting a fluid such as water W or gas into the gap 10 and water is fed from a water tank 14 or gas holder into an inlet 12A.
- a cap 16 is threadedly fitted to the rear portion of the adaptor 12 and an O-ring 18 is fitted so as to abut against the tube 4 for constituting water-tight structure for the gap 10.
- a holder 20 made of a metallic material is disposed at the forward end portion of the laser probe.
- the holder 20 has a body portion 22 whose rear portion is stepped to form a recess around the periphery thereof to provide a fitting portion 24.
- This fitting portion 24 is tightly fitted between the tube 4 and the outer tube 8.
- the outer face of the fitting portion 24 has corrugations as shown in FIG. 3 so as to prevent slip out of the outer tube 8 from the fitting portion 24.
- the holder 20 has, at the forward portion of the body portion 22 thereof a contact member fixing portion 26 formed with a stepped portion on the inner face thereof.
- a concaved lens 28 is inserted into the fixing portion 26 and a constant tip 30 having a stepped back of a reduced diameter is fitted in front of the lens.
- the forward end of the fixing portion 26 has a cutout 32 (FIG. 3).
- the contact tip 30 is mounted in such a manner that the step is first inserted into the fixing portion 26 and fixed to the holder 20 by an adhesive 34 applied to their faces being in close contact with each other and the cutout 32.
- At least one slit for example two slits 35, 35 are formed on the holder 20 which extend from the rear end of the holder 20 over the fitting portion 24 and the body portion 22 thereof. By these slits 35, the inner space of the holder 20 is communicated with the gap 10 and the outside.
- the concaved lens 28 and the contact tip 30 cooperate to provide a contact member of the present invention. They are made of quartz or an artificial sapphire and at least the contact tip 30 is preferably made of an artificial sapphire.
- the artificial sapphire is formed into the contact member of the present invention in such a manner than the C-axis of the crystalline structure of the artificial sapphire is disposed along the longitudinal direction of the contact member.
- the artificial sapphire of the present invention has characteristics as summarized in the following:
- the artificial sapphire of this kind may be obtained by any suitable means such as a zone melting method or Verneuil method.
- the Verneuil method is advantageous over the zone melting method in respect with light transmission and therefore Verneuil method is preferably employed to manufacture the artificial saphire of the present invention.
- the material i.e., Al 2 O 3 powder is subjected to melting at a temperature of about 2040° C. and dropped by gravity through a nozzle to allow crystallization to take place.
- the artificial sapphire employed for the contact member has such advantages that it is physiologically neutral, has high mechanical strength, high hardness, high laser beam transmission, excellent thermal resistance and low thermal conductivity and is free from tissue adhesion, which are all required for the material of the contact member of the laser probe.
- the thermal conductivity of the artificial sapphire is as low as 1/10 of the thermal conductivity of the quartz. This feature enbles the laser probe to be used in contact with the tissue.
- the periphery of the forward end face of the contact tip 30 is preferably rounded in a curvature preferably in a circular curvature 36 as shown in FIGS. 2 and 4 (as best shown).
- the contact tip may have an angular, for example right-angle periphery as depicted by 36' of a contact tip 30' in FIG. 5.
- the angular periphery 36' is strongly pressed against the tissue M, the coagulated blood etc. under the portion of the tissue which is undergoing the pressure by the contact tip 30' cannot flow out so that a desired effect cannot be obtained.
- the coagulated blood S can be expelled smoothly as shown in FIG. 6 by the reason not known definitely.
- the rounding of the periphery of the tip end of the contact tip is also desired because it reduces concentration of stress due to heat generated through contact with the tissue and it is effective to prevent possible breakage of the contact member.
- the radius of the curvature 36 is generally within the range of from 0.1 to 0.5 mm and preferably 0.15 to 0.3 mm. If the radius of the curvature is too small, the expelling of the coagulated blood is not carried out smoothly, while if the radius is too large, the effective laser emitting area (area of the forward end face) of the contact tip 30 is reduced and the degree of scattering is increased.
- the concave lens 28 is employed to enlarge the divergency angle ⁇ o (generally 7° to 10°) of laser beam from the optical fiber 2 and obtain an irradiation angle of ⁇ .
- a concaved curved face 300a may be formed integrally with a contact tip 300.
- a commercially available concave lens may advantageously be employed to lower the manufacturing cost.
- the laser probe of the present invention is used in the manner as described hereinafter.
- laser beam output from the laser source 6 is transmitted through the optical fiber 2 and emitted from the forward end of the optical fiber at a divergency angle ⁇ o of 7° to 10°.
- the laser beam is refracted by the concave lens 28 and thereafter passed through the lens 28 and the contact tip 30 and emitted from the forward end of the contact tip 30 at an angle of 20° to 45°, preferably 25° to 40°.
- This emission of laser beam is carried out while keeping the contact tip 30 inserted into a body for example through an endoscope in contact with the tissue M.
- water is supplied from the water tank 14 under a pressure as low as it flows only dropwise.
- the water is fed through the inlet 12A and passed through the gap 10 and the slit 35.
- the water W passing through the slit 35 enters a space defined by the holder 20, the concave lens 28 and the forward end of the tube 4 to cool the forward end of the optical fiber 2 and thereafter the water is discharged from the slit 35.
- the laser probe of the present invention as described above is especially effective for hemostasis of digestive organ.
- the contact tip 30, the holder 22 and the outer tube 8 are assembled in such a manner that the outer surfaces thereof constitute a smooth or flush surface to facilitate introduction of the probe into the body for endoscopic treatment.
- the outer diameter of the contact tip 30 may be smaller than that of the holder 22, but desired emitting angle ⁇ cannot be obtained if the diameter of the contact tip 30 is to small.
- the contact tip 30 have dimensions of FIG. 8 as specified by 1.5 ⁇ b ⁇ 5.0 (mm) and 1.5 ⁇ e+f ⁇ 5.0 (mm).
- the present invention can provide a high irradiation effect as compared with the conventional technique. And desired treatment can be obtained with a reduced laser output.
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- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
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- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Heart & Thoracic Surgery (AREA)
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Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/612,674 US4592353A (en) | 1984-05-22 | 1984-05-22 | Medical and surgical laser probe |
JP59502779A JPS61502168A (ja) | 1984-05-22 | 1984-07-17 | 内科および外科用レ−ザ探針 |
PCT/US1984/001126 WO1985005263A1 (en) | 1984-05-22 | 1984-07-17 | Medical and surgical laser probe ii |
AU31555/84A AU3155584A (en) | 1984-05-22 | 1984-07-17 | Medical and surgical laser probe ii |
EP84902888A EP0187744A1 (de) | 1984-05-22 | 1984-07-17 | Medizinisce und chirurgische lasersonde |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/612,674 US4592353A (en) | 1984-05-22 | 1984-05-22 | Medical and surgical laser probe |
Publications (2)
Publication Number | Publication Date |
---|---|
US4592353A true US4592353A (en) | 1986-06-03 |
US4592353B1 US4592353B1 (de) | 1989-04-18 |
Family
ID=24454177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US06/612,674 Expired - Lifetime US4592353A (en) | 1984-05-22 | 1984-05-22 | Medical and surgical laser probe |
Country Status (5)
Country | Link |
---|---|
US (1) | US4592353A (de) |
EP (1) | EP0187744A1 (de) |
JP (1) | JPS61502168A (de) |
AU (1) | AU3155584A (de) |
WO (1) | WO1985005263A1 (de) |
Cited By (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4736743A (en) * | 1986-05-12 | 1988-04-12 | Surgical Laser Technology, Inc. | Vaporization contact laser probe |
US4760840A (en) * | 1986-12-16 | 1988-08-02 | The Regents Of The University Of California | Endoscopic laser instrument |
US4760845A (en) * | 1987-01-14 | 1988-08-02 | Hgm Medical Laser Systems, Inc. | Laser angioplasty probe |
US4781681A (en) * | 1987-09-15 | 1988-11-01 | Gv Medical, Inc. | Inflatable tip for laser catheterization |
US4817601A (en) * | 1985-03-06 | 1989-04-04 | C. R. Bard, Inc. | Catheter system for controlled removal by radiant energy of biological obstructions |
US4819630A (en) * | 1987-03-20 | 1989-04-11 | Laser Photonics, Inc. | Flexible light transmissive apparatus and method |
US4832024A (en) * | 1986-04-29 | 1989-05-23 | Georges Boussignac | Cardio-vascular catheter for shooting a laser beam |
US4849859A (en) * | 1986-04-22 | 1989-07-18 | Kabushiki Kaisha Morita Seisakusho | Laser-type handpiece |
DE3926353A1 (de) * | 1988-08-11 | 1990-02-15 | Morita Mfg | Laserbestrahlungsvorrichtung |
DE3918965A1 (de) * | 1989-01-11 | 1990-07-12 | Masahiko Hoshino | Lasergeraet fuer medizinische behandlung |
US5005944A (en) * | 1987-12-29 | 1991-04-09 | Luxar Corporation | Hollow lightpipe and lightpipe tip using a low refractive index inner layer |
US5041109A (en) * | 1986-10-27 | 1991-08-20 | University Of Florida | Laser apparatus for the recanalization of vessels and the treatment of other cardiac conditions |
DE4008217A1 (de) * | 1990-03-15 | 1991-09-26 | Wolf Gmbh Richard | Vorrichtung zur gasspuelung eines wellenleiters fuer co(pfeil abwaerts)2(pfeil abwaerts)-laser |
US5061265A (en) * | 1989-06-20 | 1991-10-29 | University Of Florida | Laser treatment apparatus and method |
US5071222A (en) * | 1987-12-29 | 1991-12-10 | Luxar Corporation | Lightpipe tip for contact laser surgery |
US5074860A (en) * | 1989-06-09 | 1991-12-24 | Heraeus Lasersonics, Inc. | Apparatus for directing 10.6 micron laser radiation to a tissue site |
US5112328A (en) * | 1988-01-25 | 1992-05-12 | Refractive Laser Research & Development Program, Ltd. | Method and apparatus for laser surgery |
US5129896A (en) * | 1989-11-13 | 1992-07-14 | Hasson Harrith M | Holder to facilitate use of a laser in surgical procedures |
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WO1993003678A1 (en) * | 1991-08-16 | 1993-03-04 | Myriadlase, Inc. | Laterally reflecting tip for laser transmitting fiber |
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US5217452A (en) * | 1992-05-18 | 1993-06-08 | Donnell Francis E O | Transscleral laser treatment of subretinal neovascularization |
US5263952A (en) * | 1992-03-25 | 1993-11-23 | Spectranetics | Two-piece tip for fiber optic catheter |
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US5290275A (en) * | 1985-03-22 | 1994-03-01 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
US5306274A (en) * | 1991-12-23 | 1994-04-26 | Laser Centers Of America | Laser-powered high temperature energy delivery tip element with throughflow of vaporized materials and electrocauterization capability |
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US5423805A (en) * | 1992-02-05 | 1995-06-13 | Angeion Corporation | Laser catheter with moveable integral fixation wires |
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US5452715A (en) * | 1993-08-26 | 1995-09-26 | Boussignac; Georges | Tube for assisting breathing |
US5468239A (en) * | 1992-04-13 | 1995-11-21 | Sorenson Laboratories, Inc. | Apparatus and methods for using a circumferential light-emitting surgical laser probe |
US5476461A (en) * | 1994-05-13 | 1995-12-19 | Cynosure, Inc. | Endoscopic light delivery system |
US5495541A (en) * | 1994-04-19 | 1996-02-27 | Murray; Steven C. | Optical delivery device with high numerical aperture curved waveguide |
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US5520681A (en) * | 1992-04-24 | 1996-05-28 | Surgical Laser Technologies, Inc. | Light energy emitting probe with inclusions distributed within and throughout probe's tip portion |
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US5549600A (en) * | 1994-07-01 | 1996-08-27 | Cynosure, Inc. | Surgical laser probe with thermal cutting |
USRE35330E (en) * | 1989-08-28 | 1996-09-17 | University Of Kansas Medical Center | Hot tip catheter assembly |
US5562657A (en) * | 1994-09-19 | 1996-10-08 | Griffin; Stephen E. | Side fire laser catheter method and apparatus |
US5571099A (en) * | 1995-05-09 | 1996-11-05 | Pioneer Optics Company | Side firing probe |
US5607420A (en) * | 1992-02-25 | 1997-03-04 | Surgical Laser Technologies, Inc. | Surgical tool for use with a contact laser |
US5658275A (en) * | 1995-06-07 | 1997-08-19 | Trimedyne, Inc. | Surgical laser instrument |
US5693043A (en) * | 1985-03-22 | 1997-12-02 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
US5707368A (en) * | 1990-10-31 | 1998-01-13 | Premier Laser Systems, Inc. | Contact tip for laser surgery |
US5755850A (en) * | 1992-09-24 | 1998-05-26 | Iowa State University Research Foundation | Method of making a surgical laser fiber from a monolithic silica titania glass rod |
US5756015A (en) * | 1995-06-06 | 1998-05-26 | Ngk Insulators, Ltd. | Method for producing cylindrical ceramic body |
US5830209A (en) * | 1992-02-05 | 1998-11-03 | Angeion Corporation | Multi-fiber laser catheter |
US5833683A (en) * | 1996-01-12 | 1998-11-10 | Surgical Laser Technologies, Inc. | Laterally-emitting laser medical device |
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Also Published As
Publication number | Publication date |
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AU3155584A (en) | 1985-12-13 |
US4592353B1 (de) | 1989-04-18 |
JPS61502168A (ja) | 1986-10-02 |
EP0187744A1 (de) | 1986-07-23 |
JPH0586225B2 (de) | 1993-12-10 |
WO1985005263A1 (en) | 1985-12-05 |
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