UA92134C2 - Соединение, обладающее анти-вгс действием, и фармацевтическая композиция, содержащая его - Google Patents

Соединение, обладающее анти-вгс действием, и фармацевтическая композиция, содержащая его

Info

Publication number
UA92134C2
UA92134C2 UAA200601259A UAA200601259A UA92134C2 UA 92134 C2 UA92134 C2 UA 92134C2 UA A200601259 A UAA200601259 A UA A200601259A UA A200601259 A UAA200601259 A UA A200601259A UA 92134 C2 UA92134 C2 UA 92134C2
Authority
UA
Ukraine
Prior art keywords
compound
composition containing
pharmaceutical composition
hcv activity
bond
Prior art date
Application number
UAA200601259A
Other languages
English (en)
Ukrainian (uk)
Inventor
Масаюки Судох
Такуо Цукуда
Мияко Масубучи
Кеничи Кавасаки
Такеши Мурата
Фумио Ватанабе
Хироши Фукуда
Сусуму Комияма
Тадакацу Хаясе
Original Assignee
Чугай Сейяку Кабушики Кайша
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Чугай Сейяку Кабушики Кайша filed Critical Чугай Сейяку Кабушики Кайша
Publication of UA92134C2 publication Critical patent/UA92134C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Epoxy Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
UAA200601259A 2003-07-09 2004-07-09 Соединение, обладающее анти-вгс действием, и фармацевтическая композиция, содержащая его UA92134C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003272420 2003-07-09

Publications (1)

Publication Number Publication Date
UA92134C2 true UA92134C2 (ru) 2010-10-11

Family

ID=34055974

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200601259A UA92134C2 (ru) 2003-07-09 2004-07-09 Соединение, обладающее анти-вгс действием, и фармацевтическая композиция, содержащая его

Country Status (18)

Country Link
US (1) US7378446B2 (ru)
EP (1) EP1661882B1 (ru)
JP (1) JP4068639B2 (ru)
KR (1) KR20060029182A (ru)
CN (1) CN1819990B (ru)
AU (1) AU2004255633B2 (ru)
BR (1) BRPI0412459A (ru)
CA (1) CA2531790A1 (ru)
HK (1) HK1093485A1 (ru)
IL (1) IL172666A0 (ru)
MX (1) MXPA06000294A (ru)
MY (1) MY143775A (ru)
NO (1) NO20055986L (ru)
NZ (1) NZ545102A (ru)
RU (1) RU2346933C2 (ru)
TW (1) TWI330173B (ru)
UA (1) UA92134C2 (ru)
WO (1) WO2005005372A1 (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006077004A (ja) * 2004-08-11 2006-03-23 Chugai Pharmaceut Co Ltd 抗hcv作用を有する化合物およびそれを含む医薬組成物
US8183005B1 (en) 2004-08-11 2012-05-22 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical agents for treating HCV infections
JPWO2006088071A1 (ja) * 2005-02-17 2008-07-03 中外製薬株式会社 抗hcv作用を有する化合物の製造方法およびその中間体
JPWO2007000994A1 (ja) * 2005-06-28 2009-01-22 中外製薬株式会社 抗hcv作用を有する化合物の製造方法
CN101360736A (zh) * 2005-11-23 2009-02-04 阿斯利康(瑞典)有限公司 L-丙氨酸衍生物
CN101489580A (zh) 2006-05-16 2009-07-22 财团法人东京都医学研究机构 治疗或预防hcv感染症的药物组合物
JP2009539815A (ja) * 2006-06-09 2009-11-19 アストラゼネカ アクチボラグ 固形腫瘍の治療用のa5b1アンタゴニストとしてのN−(ベンゾイル)−O−[2−(ピリジン−2−イルアミノ)エチル]−L−チロシン誘導体と関連化合物
US20090062267A1 (en) * 2007-01-29 2009-03-05 Astrazeneca Ab L-ALANINE DERIVATIVES AS a5beta1 ANTAGONISTS
WO2008125811A1 (en) * 2007-04-11 2008-10-23 Astrazeneca Ab N-[HETEROARYLCARBONYL]-S-THIENYL-L-ALANINE DERIVATIVES AS α5β1 ANTAGONISTS
TW201010692A (en) 2008-06-19 2010-03-16 Public Univ Corp Nagoya City Univ Pharmaceutical composition for treatment or prevention of hbv infection
EP2610343A3 (en) 2008-11-26 2013-09-25 Chugai Seiyaku Kabushiki Kaisha Method for designing siRNA and oligoribonucleotides inhibiting HCV
JP2013121935A (ja) * 2011-12-12 2013-06-20 Institute Of Microbial Chemistry 化合物、及び不斉合成反応
EP2886530A4 (en) 2012-08-17 2016-01-27 Chugai Pharmaceutical Co Ltd ORAL ADMINISTRATIVE VIRIDIDEIN DERIVATIVE WITH ANTI-HCV ACTIVITY

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364948A (en) * 1991-08-02 1994-11-15 Merck & Co., Inc. Biologically active compounds isolated from aerobic fermentation of Trichoderma viride
EP0526936A3 (en) * 1991-08-02 1993-05-05 Merck & Co. Inc. Cholesterol-lowering agents
US5503973A (en) 1992-05-29 1996-04-02 The Regents Of The University Of California Method for inhibition of viral morphogenesis
US6303350B1 (en) * 1997-06-09 2001-10-16 Takara Shuzo Co., Ltd. Physiologically active substances TKR2449, process for producing the same, and microorganism
JP5025051B2 (ja) 2001-07-26 2012-09-12 サトーホールディングス株式会社 印字編集処理装置
JP4093534B2 (ja) 2002-03-15 2008-06-04 スタンレー電気株式会社 車両用前照灯
MY141506A (en) 2003-02-12 2010-05-14 Chugai Pharmaceutical Co Ltd Virus therapeutic drug

Also Published As

Publication number Publication date
EP1661882A1 (en) 2006-05-31
HK1093485A1 (en) 2007-03-02
WO2005005372A1 (ja) 2005-01-20
IL172666A0 (en) 2006-04-10
TWI330173B (en) 2010-09-11
CN1819990A (zh) 2006-08-16
US7378446B2 (en) 2008-05-27
JP4068639B2 (ja) 2008-03-26
MXPA06000294A (es) 2006-04-18
AU2004255633A1 (en) 2005-01-20
NO20055986L (no) 2006-02-13
CN1819990B (zh) 2010-04-21
RU2346933C2 (ru) 2009-02-20
EP1661882B1 (en) 2013-10-30
US20060194870A1 (en) 2006-08-31
CA2531790A1 (en) 2005-01-20
MY143775A (en) 2011-07-15
EP1661882A4 (en) 2007-01-31
TW200524847A (en) 2005-08-01
BRPI0412459A (pt) 2006-10-17
AU2004255633B2 (en) 2009-08-06
RU2006103803A (ru) 2006-08-10
JPWO2005005372A1 (ja) 2006-08-24
NZ545102A (en) 2008-11-28
KR20060029182A (ko) 2006-04-04

Similar Documents

Publication Publication Date Title
CA2445744A1 (en) Antiviral nucleoside derivatives
MY128463A (en) 4' substituted nucleosides for the treatment of diseases mediated by the hepatitis c virus
DE69637511D1 (de) Verwendung von Ritonavir (abt-538) zur Verbesserung der Pharmakokinetik von Arzneimitteln, die durch Cytochrom p450 metabolisiert werden, im Rahmen einer Behandlung von Aids
UA92134C2 (ru) Соединение, обладающее анти-вгс действием, и фармацевтическая композиция, содержащая его
CA2449572A1 (en) 4'-substituted nucleosides
NO20052130L (no) Sterk inhibitor for HCV-serin-protease
EP1400529A4 (en) GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL AND INTERMEDIARY USE THEREOF
CA2320233A1 (en) Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof
MXPA01006474A (es) Derivados colquinol como agentes perjudiciales vasculares.
GB9914486D0 (en) Medicaments
HUP0300327A2 (hu) Percyquinnin, eljárás előállítására és gyógyászati alkalmazása
IT1255222B (it) Fosforotidati di oligonucleotidi ciclici
MXPA04005156A (es) Antagonistas del receptor de adenosina a2a.
IL111674A0 (en) 5,6-Dihydropyrone derivatives and pharmaceutical compositions containing them
CA2412047A1 (en) Shortened synthesis of 3,3-diarylpropylamine derivatives
IL111673A (en) 5,6-Dihydropyrone derivatives and pharmaceutical compositions containing them
MY141506A (en) Virus therapeutic drug
CA2072416A1 (en) Cyclopropenone derivatives
WO2003039450A3 (en) Improvements in or relating to inhibition of viruses
GB2075499A (en) Nonaprenylamine derivatives
CA2072106A1 (en) Cephalosporin compounds and method for producing them
WO2001051055A3 (en) Pharmaceutical compositions containing steroidal structures and uses thereof
AP9801235A0 (en) Erythromycin derivatives.
BR0008493A (pt) Modificação cristalina c de 8-ciano-1-ciclopropil-7-(is,6s-2,8-diazabiciclo [4.3.0]nonan-8-ila)-6-flúor-1,4-dihidro-4-oxo-3-quinolin carbono
EP0414903A4 (en) New thioproline derivative