UA101478C2 - Соединения, полезные как ингибиторы raf-киназы - Google Patents
Соединения, полезные как ингибиторы raf-киназыInfo
- Publication number
- UA101478C2 UA101478C2 UAA200913589A UAA200913589A UA101478C2 UA 101478 C2 UA101478 C2 UA 101478C2 UA A200913589 A UAA200913589 A UA A200913589A UA A200913589 A UAA200913589 A UA A200913589A UA 101478 C2 UA101478 C2 UA 101478C2
- Authority
- UA
- Ukraine
- Prior art keywords
- inhibitors
- protein kinase
- compounds useful
- raf protein
- raf
- Prior art date
Links
- 102000001253 Protein Kinase Human genes 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 108060006633 protein kinase Proteins 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94729107P | 2007-06-29 | 2007-06-29 | |
PCT/US2008/068762 WO2009006389A2 (fr) | 2007-06-29 | 2008-06-30 | Composés utiles en tant qu'inhibiteurs de la kinase raf |
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- 2008-06-30 UA UAA200913589A patent/UA101478C2/ru unknown
- 2008-06-30 ES ES17168722T patent/ES2776169T3/es active Active
- 2008-06-30 ES ES08772238.5T patent/ES2635729T3/es active Active
- 2008-06-30 RU RU2009149214/04A patent/RU2492166C2/ru active
- 2008-06-30 CA CA2693182A patent/CA2693182C/fr active Active
- 2008-06-30 DK DK17168722.1T patent/DK3231798T3/da active
- 2008-06-30 CN CN200880022788.9A patent/CN101784545B/zh active Active
- 2008-06-30 AU AU2008273002A patent/AU2008273002C1/en active Active
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2009
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2012
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2016
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