TWM467056U - Apparatuses for optical inspecting biochemical test strips - Google Patents
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本申請所請新型創作係關於一種光學檢測生化試片之裝置，特別係關於藉由全像掃描識別技術進行自動光學檢測生化試片之裝置。The new creative department of the present application relates to a device for optically detecting biochemical test strips, and more particularly to a device for automatically optically detecting biochemical test strips by holographic scanning recognition technology.
在飲食富足的現代，因飲食習慣所造成的疾病越來越多，對需要長時間監控身體狀態(如血糖、血脂等)的人們來說，可信賴之生化試片於是益發顯得重要且為生活中不可或缺的工具。In the modern diet, there are more and more diseases caused by eating habits. For people who need to monitor their body status for a long time (such as blood sugar, blood lipids, etc.), reliable biochemical test strips are important and life-oriented. An indispensable tool.
傳統生化試片主要係由裸片、電極、藥劑等構件精密地組成。由於傳統生化試片具有複雜的生產過程及高精密度的品質特性，而易產出不良品，倘若消費者誤用不良產品，致使誤判身體狀況，不僅影響受測使用者身體狀況，亦與業者商譽有直接關係，故生化試片業者首重測試片的生產過程良率的管控。Traditional biochemical test strips are mainly composed of components such as bare chips, electrodes, and pharmaceuticals. Because traditional biochemical test strips have complex production processes and high-precision quality characteristics, they are easy to produce defective products. If consumers misuse bad products, they will misjudge the physical condition, which not only affects the physical condition of the tested users, but also trades with the industry. Reputation has a direct relationship, so the biochemical test film industry's first test film production process control.
在品管上，目前業界對生化試片之試劑量、隔層狀況、電極層或汙損等影響試片良率因素一般將生產完成之測試片以人工抽樣一定比例之成品進行試驗。此抽驗方式不僅提高製造成本及時間，且未能對所有測試片進行檢測，導致測試批樣雖為通過品管測試，然而仍無法完全避免不良品的存在，因此人力抽檢方式已不符合現今生化試片業者需求。In quality control, the current industry's factors affecting the yield of the biochemical test strips, the condition of the interlayer, the electrode layer or the fouling, etc., generally test the finished test piece by manually sampling a certain proportion of the finished product. This sampling method not only increases the manufacturing cost and time, but also fails to test all the test pieces, resulting in the test batch being passed the quality control test, but still can not completely avoid the existence of defective products, so the manual sampling method is not in line with the current biochemical Test film industry needs.
於習知技術中，參見中華民國發明專利申請案第082101821號(現公告號：277164)揭露一種自動檢查及鑑別物體或表面之不同顏色區域的方法，利用電荷耦合元件掃描技術(Charge-Coupled Device，以下簡稱CCD)辨識電路板或固態晶片等電子元件之內部情況做為品檢方法，然而傳統CCD技術僅為待測物反射之光像並備有與該物體或表面之各不同著色區域相對應的不同顏色濾光器搭配進行分析運算後得知該待測物局部之情況，未能一次性將待測物整體結構及精準色澤完整呈現。此外，若採用如中華民國發明專利第I365298號所揭露利用X光掃描待測物內部，再利用可見光掃描待測物表面，並將兩者合而為一的方法。因生化試片內具有對光敏感之化學成分，例如赤血鐵會使其產生化學變化而喪失預設功能，是故業界面對強光破壞，弱光不足呈現結構之問題。In the conventional technology, see the Republic of China invention patent application No. 08101821 (present publication number: 277164) discloses a method for automatically inspecting and identifying different color regions of an object or surface, using charge coupled device scanning technology (Charge-Coupled Device) Hereinafter referred to as CCD), the internal condition of an electronic component such as a circuit board or a solid-state chip is used as a quality inspection method. However, the conventional CCD technology is only a light image reflected by the object to be tested and is provided with different colored regions of the object or surface. Corresponding different color filters are combined with the analysis and calculation to know the local condition of the object to be tested, and the overall structure and accurate color of the object to be tested cannot be completely presented at one time. In addition, if the inside of the object to be tested is scanned by X-rays as disclosed in the Chinese Patent No. I365298, the surface of the object to be tested is scanned by visible light, and the two are combined into one. Because the chemical components sensitive to light in the biochemical test strips, such as red blood iron, cause chemical changes and lose the preset function, the industry faces the problem of strong light damage and weak light deficiency.
有鑑於此，如何對生化試片進行高精準良率品管檢驗，長久以來已成為業界亟欲解決之問題。In view of this, how to conduct high-accuracy yield quality inspection of biochemical test strips has long been a problem that the industry is trying to solve.
本新型創作之一實施例提供一種光學檢測生化試片裝置，包含：一掃描單元以處理一待測生化試片之一掃描影像；一傳動標註單元將該待測生化試片傳輸至該影像處理單元，並根據影像處理結果進行標註；以及一控制單元分別控制該掃描單元進行圖像掃描及對該傳動標註單元下達標註指令。An embodiment of the present invention provides an optical detection biochemical test strip device, comprising: a scanning unit for processing a scanned image of a biochemical test piece to be tested; and a transmission labeling unit for transmitting the biochemical test piece to be tested to the image processing The unit is labeled according to the image processing result; and a control unit controls the scanning unit to perform image scanning and issue a labeling instruction to the transmission labeling unit.
所述掃描單元包括一光源器、一影像處理器、及一可調平台，對該待測生化試片進行影像掃描及圖像分析。The scanning unit includes a light source, an image processor, and an adjustable platform for performing image scanning and image analysis on the biochemical test piece to be tested.
所述傳動標註單元包含一傳送機構及一標註機。所述控制單 元包含一人機介面、一主控電腦及一資料處理器，分別控制該掃描單元進行圖像掃描及並根據影像處理結果對該傳動標註單元下達標註指令。The transmission marking unit comprises a conveying mechanism and a marking machine. The control list The unit includes a human machine interface, a main control computer and a data processor, respectively controlling the scanning unit for image scanning and issuing an instruction to the transmission labeling unit according to the image processing result.
100‧‧‧光學檢測生化試片裝置100‧‧‧Optical detection biochemical test strip device
110‧‧‧控制單元110‧‧‧Control unit
112‧‧‧人機介面112‧‧‧Human Machine Interface
114‧‧‧主控電腦114‧‧‧Master computer
116‧‧‧資料處理器116‧‧‧ Data Processor
120‧‧‧掃描單元120‧‧‧ scan unit
122‧‧‧光源器122‧‧‧Light source
1221‧‧‧發光元件1221‧‧‧Lighting elements
124‧‧‧影像處理器124‧‧‧Image Processor
1241‧‧‧影像處理元件1241‧‧‧Image Processing Components
12411‧‧‧第一影像處理元件12411‧‧‧First image processing component
12412‧‧‧第二影像處理元件12412‧‧‧Second image processing component
12413‧‧‧第三影像處理元件12413‧‧‧ Third image processing component
126‧‧‧可調平台126‧‧‧Adjustable platform
1261‧‧‧濾光器1261‧‧‧ Filter
1262‧‧‧生化試片1262‧‧‧Biochemical test strips
130‧‧‧傳動標註單元130‧‧‧Transmission marking unit
132‧‧‧傳送機構132‧‧‧Transportation agency
134‧‧‧標註機134‧‧‧Marking machine
S210~S280‧‧‧操作步驟S210~S280‧‧‧ operation steps
本新型創作藉由下列實施方式及配合相對應的圖式詳細說明，俾能更深入之了解本創作，其中：圖1顯示根據本新型創作實施例之光學檢測生化試片裝置的模組化方塊示意圖；圖2為本新型創作實施例之掃描單元示意圖；及圖3顯示根據本新型創作實施例之生化試片之光學檢測方法的操作流程示意圖。The present invention can be more deeply understood by the following embodiments and the corresponding drawings, wherein: FIG. 1 shows a modular block of an optical detection biochemical test device according to the present creative embodiment. 2 is a schematic diagram of a scanning unit of a novel embodiment of the present invention; and FIG. 3 is a flow chart showing the operation of an optical detecting method for a biochemical test piece according to an embodiment of the present invention.
以下以各實施例詳細說明並伴隨著圖式說明之範例，作為本新型創作之參考依據。在圖式或說明書描述中，相似或相同之部分皆使用相同之圖號。且在圖式中，實施例之形狀或是厚度可擴大，並以簡化或是方便標示。再者，圖式中各元件之部分將以分別描述說明之，值得注意的是，圖中未繪示或描述之元件，為所屬技術領域中具有通常知識者所知的形式，另外，特定之實施例僅為揭示本新型創作使用之特定方式，其並非用以限定本新型創作。The following is a detailed description of various embodiments and examples accompanying the drawings, as a reference for the creation of the present invention. In the drawings or the description of the specification, the same drawing numbers are used for similar or identical parts. In the drawings, the shape or thickness of the embodiment may be expanded and simplified or conveniently indicated. In addition, the components of the drawings will be described separately, and it is noted that the components not shown or described in the drawings are known to those of ordinary skill in the art, and in particular, The examples are merely illustrative of the specific ways in which the novels are used, and are not intended to limit the present invention.
本新型創作之實施例提供一種光學檢測生化試片之裝置，藉由全像掃描方法並有效地整合精密運動控制技術、影像處理分析技術、與自動化機械設計等實用技術，搭配製程生產技術知識，對生化試片實施全面性地檢測，以有效提高整體生產良率，達到高度自動化檢測目的，並實 現自動光學檢測(automatic optic inspection，簡稱AOI)技術於試片生技產業上。The embodiment of the novel creation provides a device for optically detecting biochemical test strips, and comprehensively integrates precision motion control technology, image processing analysis technology, and automatic mechanical design with a holographic scanning method, and cooperates with process production technical knowledge. Conduct comprehensive testing on biochemical test strips to effectively improve overall production yield and achieve highly automated testing purposes. Automatic optical inspection (AOI) technology is now used in the test strip biotechnology industry.
請參閱圖1，於一實施例中，提供一種光學檢測生化試片裝置100，主要由一控制單元110、一掃描單元120及一傳動標註單元130所組合而成。掃描單元120包含一光源器122或一線型CCD，一影像處理器124及一可調平台126，主要用以處理生化試片之掃描影像。該影像處理器124包含一全像掃描擷取影像裝置。傳動標註單元130包含一傳送機構132及一標註機134，將生化試片傳輸至該掃描單元120，並根據影像處理結果進行標註。控制單元110包含一人機介面112、一主控電腦114、及一資料處理器116，分別控制掃描單元120進行圖像掃描及並根據影像處理結果對該傳動標註單元130下達標註指令。於一操作範例中，待測生化試片基板可藉由傳送機構132置入掃描單元120(例如全像掃描裝置)之可視野範圍內進行掃描取像分析演算，爾後將試片影像演算結果與主控電腦114內建之製程計量參數比對，其比對結果呈現於控制單元110中所設計之視覺化人機介面112上，並將檢測結果儲存於資料儲存器116內，同時啟動一標註機134移動平台將試片良品與不良品分類及標註，以利後續品管作業。Referring to FIG. 1 , in an embodiment, an optical detection biochemical test strip device 100 is provided, which is mainly composed of a control unit 110 , a scanning unit 120 and a transmission labeling unit 130 . The scanning unit 120 includes a light source 122 or a linear CCD, an image processor 124 and an adjustable platform 126 for processing scanned images of biochemical test strips. The image processor 124 includes a holographic image capture image device. The transmission labeling unit 130 includes a transport mechanism 132 and a labeling machine 134. The biochemical test strip is transmitted to the scanning unit 120 and labeled according to the image processing result. The control unit 110 includes a human interface 112, a main control computer 114, and a data processor 116. The scanning unit 120 is controlled to perform image scanning and to issue an instruction to the transmission labeling unit 130 according to the image processing result. In an operation example, the biochemical test strip substrate to be tested can be placed in the field of view of the scanning unit 120 (for example, the holographic scanning device) by the transport mechanism 132 to perform scanning image analysis calculation, and then the test image image calculation result is The process measurement parameters of the built-in computer 114 are compared, and the comparison result is presented on the visual human-machine interface 112 designed in the control unit 110, and the detection result is stored in the data storage 116, and an annotation is started. The machine 134 mobile platform classifies and labels the test pieces and defective products to facilitate subsequent quality control operations.
請參閱圖2為本新型創作之掃描單元120，包括一光源器122、一影像處理器124及一可調平台126。其中光源器122用以提供光線照射一待測生化試片1262，且為配合待測生化試片結構不同或藥劑情況，該光源器122可產生不同波長或強度之光源；另該光源可以由數個不同波長及光強度的發光元件1221亦可由可單一發射不同光波長之發光元件或單一光波之發光元件所組成。如分別投射480nm的第一光線及620nm之第二光線， 故可擷得不同灰階的第一及第二影像。Referring to FIG. 2 , the scanning unit 120 of the present invention includes a light source 122 , an image processor 124 , and an adjustable platform 126 . The light source 122 is configured to provide light to be irradiated to the biochemical test piece 1262 to be tested, and the light source 122 can generate light sources of different wavelengths or intensities according to different structures of the biochemical test pieces to be tested or the medicament; and the light source can be counted by The light-emitting elements 1221 of different wavelengths and light intensities may also be composed of light-emitting elements that can emit light of different light wavelengths or light-emitting elements of a single light wave. For example, a first light of 480 nm and a second light of 620 nm are respectively projected. Therefore, the first and second images of different gray levels can be obtained.
影像處理器124可相對光源器122之發光元件1221數量而設置多個影像處理元件1241，且該影像處理元件1241係依據其所對應之發光元件進行感光，如在一掃描過程中，光源器122共提供了三種不同光波，則影像處理器124則需由三個影像處理元件1241或由多個處理元件1241交替使用，進而得到多個不同灰階的影像。在一最佳實施例中，各影像處理元件1241可依據不同景深進行對焦調整，以得到最佳影像，如第一影像處理元件12411對焦於裸片上，第二影像處理元件12412對焦於電極層上，第三影像處理元件12413對焦於藥劑層上，並配合各發光元件1221得到各層結構之影像並將其合成為一完整試片結構影像。The image processor 124 can provide a plurality of image processing elements 1241 relative to the number of light-emitting elements 1221 of the light source 122, and the image processing elements 1241 are sensitive according to the corresponding light-emitting elements, such as a light source 122 during a scanning process. A total of three different light waves are provided, and the image processor 124 needs to be alternately used by three image processing elements 1241 or by a plurality of processing elements 1241 to obtain a plurality of images of different gray levels. In a preferred embodiment, each image processing component 1241 can perform focus adjustment according to different depth of field to obtain an optimal image. For example, the first image processing component 12411 focuses on the die, and the second image processing component 12412 focuses on the electrode layer. The third image processing component 12413 focuses on the drug layer, and cooperates with each of the light-emitting elements 1221 to obtain an image of each layer structure and synthesizes it into a complete sample structure image.
可調平台126，其可以利用夾持、透明平台等方式固定於掃描單元120中，且為使待測試片可得到最佳的光照，該平台係可進行離光距離調整，該調整方式係可於在平台上設置可動馬達(圖未示)或由人力進行調整。另該可調平台126亦可設置濾光器1261於入光處，避免非預設之光波照射至待測試片上，進而提高掃描效能，亦可避免對待測試片受有害之光波破壞。The adjustable platform 126 can be fixed in the scanning unit 120 by means of a clamping, a transparent platform, etc., and the platform can perform the distance adjustment of the optical distance in order to obtain optimal illumination of the piece to be tested. A movable motor (not shown) is provided on the platform or adjusted by manpower. In addition, the adjustable platform 126 can also be provided with the filter 1261 at the entrance light to prevent non-preset light waves from being irradiated onto the film to be tested, thereby improving the scanning performance and avoiding damage to the test piece by harmful light waves.
為取得最佳掃描圖像，本新型創作之光源器122與影像處理器124係透過主控電腦114進行控制，主控電腦114可針對光源器122之發光元件1221進行光強或/及影像處理器124之焦距及平台高度進行校正。例如在一掃描過程中，主控電腦114判斷該掃描影像模糊，則會透過人機介面112提醒操作員或自動進行調整，以達到最佳掃描圖像。In order to obtain the best scanned image, the light source 122 and the image processor 124 of the present invention are controlled by the main control computer 114, and the main control computer 114 can perform light intensity or/and image processing on the light-emitting element 1221 of the light source 122. The focal length of the 124 and the height of the platform are corrected. For example, during a scanning process, the main control computer 114 determines that the scanned image is blurred, and the operator interface 112 is used to remind the operator or automatically adjust to achieve the best scanned image.
在一實施例中，操作人員先行置入一待測試片到可調平台 126上，並啟動掃描，光源器122依據主控電腦114之設定提供特定光波及光強之掃描光，影像處理器124亦依照主控電腦114指令擷取影像，並將該擷取之影像轉換成特定檔案傳送至主控電腦114；主控電腦114接收到該測試影像後透過資料處理器116內存之數據分析出一最佳光波長、光強、影像處理元件數、曝光時間、可調平台126高度等數據調整掃描單元120各元件以達到最佳影像掃描，並將該調整數據儲存至資料處理器中。In an embodiment, the operator first inserts a test piece into the adjustable platform. 126, and start scanning, the light source 122 provides scanning light of specific light waves and light intensity according to the setting of the main control computer 114, and the image processor 124 also captures images according to the instruction of the main control computer 114, and converts the captured image. The specific file is transmitted to the main control computer 114; after receiving the test image, the main control computer 114 analyzes the optimal optical wavelength, the light intensity, the number of image processing components, the exposure time, and the adjustable platform through the data stored in the data processor 116. 126 height and other data adjust the components of the scanning unit 120 to achieve optimal image scanning, and store the adjustment data in the data processor.
掃描單元120將該掃描結果傳送至主控電腦114後，主控電腦114依據該掃描結構快速分析出生化試片藥劑位置、電極方向、圖形等特徵，進而得知掃描試片之相位(正反面)，並依據各試片整體特徵定位出各生化試片的確實位置，再經由資料處理器116預設或/及人機介面112之數據對該掃描試片之內部元件之色階、影像、幾何等特徵進行分析比對，進而可得知不良品之位置及狀況。該掃描試片經人工或自動化設備送至標註機134後，標註機依據資料處理器所定位不良品位置及分類進行標註。於一實施例中，該該標註機134可針對不同的不良狀況進行個別標註，例如藥劑有問題標黃色，電極有問題標藍色。After the scanning unit 120 transmits the scan result to the main control computer 114, the main control computer 114 quickly analyzes the position, the electrode direction, the graphic and the like of the birth test piece according to the scanning structure, and further knows the phase of the scanned test piece (front and back). And positioning the actual position of each biochemical test piece according to the overall characteristics of each test piece, and then using the data processor 116 to preset or/and the data of the human machine interface 112, the color level, image, and internal components of the scanned test piece. The characteristics such as geometry are analyzed and compared, and the position and condition of the defective product can be known. After the scanning test piece is sent to the marking machine 134 by manual or automated equipment, the marking machine is marked according to the position and classification of the defective product positioned by the data processor. In an embodiment, the labeling machine 134 can be individually labeled for different bad conditions, for example, the medicine has a problem mark yellow, and the electrode has a problem mark blue.
本新型創作實施例之光學檢測生化試片裝置可設置於自動化產線中實施自動上下料，亦能拆解為單站作業人工置料。例如，可搭配自動化控制的送料/收料裝置而整合於自動化產線中。The optical detection biochemical test strip device of the novel creation embodiment can be installed in an automated production line to implement automatic loading and unloading, and can also be disassembled into a single station for manual loading. For example, it can be integrated into an automated production line with an automated controlled feed/receiver.
請參閱圖3，於另一實施例中，提供一種生化試片之光學檢測方法，包含以下步驟：於系統接收開始(S210)檢測指令後，進行資料設定步驟(S220)以設定一檢測資料。接著，進行將待測物置於平台步驟(S230)，例如將一待測生化試片設置於一掃描平台並啟動掃描步驟(S240)，之後分析 由該掃描步驟所得之掃描結果(S250)。根據該掃描結果進行瑕疵標註的判斷步驟(S260)，以選擇進行資料儲存(S265)或者將該待測生化試片分類(S270)，如無進一步的待測試片，則結束(S280)本測試方法。於另一操作範例中，藉由控制單元中的人機界面輸入指令，透過影像處理單元進行圖像掃描並將結果傳送回控制單元，接著由控制單元下達標註指令，進而將待測物進行分類並置入新待測物。應瞭解的是，所述生化試片之光學檢測方法的實施方式可替選地以手動或以自動操作，一般的掃描作業都可以在短時間內利用光學機構與軟體程式的架構完成，由此可提升系統的速度並降低誤判率。Referring to FIG. 3, in another embodiment, an optical detection method for a biochemical test strip is provided, comprising the steps of: after the system receives the start (S210) detection instruction, performing a data setting step (S220) to set a detection data. Then, the object to be tested is placed in the platform step (S230), for example, a biochemical test piece to be tested is set on a scanning platform and the scanning step is started (S240), and then analyzed. The scan result obtained by this scanning step (S250). Performing a step of judging the mark according to the scan result (S260), selecting to perform data storage (S265) or classifying the biochemical test piece to be tested (S270), and if there is no further test piece to be tested, ending (S280) the test method. In another operation example, by inputting an instruction through a human-machine interface in the control unit, the image processing unit performs image scanning and transmits the result back to the control unit, and then the control unit issues an annotation instruction to classify the object to be tested. And put in the new object to be tested. It should be understood that the embodiment of the optical detection method of the biochemical test piece may alternatively be manually or automatically operated, and the general scanning operation can be completed in a short time by using the structure of the optical mechanism and the software program. It can increase the speed of the system and reduce the false positive rate.
本新型創作實施例之生化試片之光學檢測方法可應用於檢測生化試片上藥劑的顏色、電極的間距、人為汙損等特徵並進行分析比對。特別是，可針對生化試片上色差而決定藥劑的量。The optical detection method of the biochemical test piece of the novel creation embodiment can be applied to the detection of the color of the agent on the biochemical test piece, the spacing of the electrodes, the artificial fouling and the like, and the analysis is performed. In particular, the amount of the agent can be determined for the color difference of the biochemical test piece.
本新型創作上述揭露之檢測方法的優點在於，上述實施例利用全像掃描方法自動比對及排除，無須再利用成品抽驗，故有效降低生產所需時間及費用之功效。採用全像掃描方法原因為根據試片藥劑所呈現出來的顏色也能做為判斷依據，例如一般測試片上的藥劑顏色係黃色，但如果該藥劑受到溫度、潮濕、紫外線之污染而不堪使用，則會變成其他顏色。再者，根據本新型創作實施例，利用波長範圍420nm~700nm的可見光進行掃描，故無需利用透光器將衰減光強度，改變光譜成分或限定振動面即可進行掃描，可一次性對不同顏色、幾何形狀之待測物進行掃描分析，提高掃描速度及準確度。因本新型創作實施例對生化試片進行掃描，而試片藥劑成分對於短波長極為敏感，例如血糖測試片中所含的三價鐵極容易與紫 外線發生作用，導致藥劑喪失其預設功能，故在血糖測試片中不能使用具有紫外線光之掃描光源。經研究發現生化試片對於波長界於420~750nm之光源對生化試片影響最小，因此本新型創作係利用420~750nm之波長光源進行光學檢測。再者，可針對試片內部元件之色階、影像、幾何等特徵進行分析比對，亦因生產前置內建已知相關特徵參數，故透過全像掃描擷取線上待測試片影像資訊，將內建參數與線上掃描分析參數結果進行分析比對，而予以分類，以提高整體成品良率。The invention has the advantages that the above detection method has the advantages that the above embodiment automatically aligns and eliminates the holographic scanning method, and does not need to use the finished product sampling test, thereby effectively reducing the time and cost required for production. The holographic scanning method is based on the fact that the color exhibited by the test piece can also be used as a basis for judging. For example, the color of the drug on the general test piece is yellow, but if the agent is not contaminated by temperature, humidity or ultraviolet rays, then Will become other colors. Furthermore, according to the creative embodiment of the present invention, the visible light is scanned by using the visible light having a wavelength range of 420 nm to 700 nm, so that the light intensity can be attenuated by using the light transmissive device, the spectral component or the vibration surface can be changed, and the color can be scanned at one time. The geometric shape of the object to be tested is scanned and analyzed to improve the scanning speed and accuracy. The biochemical test piece is scanned by the novel creation embodiment, and the test tablet component is extremely sensitive to short wavelengths, for example, the trivalent iron contained in the blood glucose test piece is extremely easy to be purple The external line acts to cause the drug to lose its preset function, so a scanning light source with ultraviolet light cannot be used in the blood glucose test piece. It has been found that biochemical test strips have the least influence on biochemical test strips for light sources with wavelengths between 420 and 750 nm. Therefore, the novel creation system uses optical wavelengths of 420-750 nm for optical detection. Furthermore, the color gradation, image, geometry and other features of the internal components of the test piece can be analyzed and compared, and the known feature parameters are built in the front of the production, so that the image of the image to be tested on the line is captured through the holographic scan. The built-in parameters are compared with the results of the online scan analysis parameters, and are classified to improve the overall yield of the finished product.
以下特例舉一實驗範例，其第一試驗步驟包含，分別使用Philips所提供365nm、450nm、530nm及640nm光源對生化試片連續照射3分鐘，並將該試片與未照射試片檢測結果進行比對，實驗發現使用365nm之光波連續照射3分鐘會導致生化試片發生約1%之誤差值，而450nm之光波會導致約0.8%之誤差；使用450nm及640nm該誤差值則在0.5%以下，然而依本新型創作概念下，掃描時間僅需約30秒即可完成，是故對掃描之試片不會造成0.3%以上的損壞。The following special example is an experimental example. The first test step includes continuously irradiating the biochemical test piece for 3 minutes using the 365 nm, 450 nm, 530 nm and 640 nm light sources provided by Philips, and comparing the test piece with the unirradiated test piece. Yes, it has been found that continuous irradiation with light waves of 365 nm for 3 minutes results in an error of about 1% in the biochemical test piece, while a light wave of 450 nm causes an error of about 0.8%; the error value of 450 nm and 640 nm is below 0.5%. However, according to the novel creation concept, the scanning time can be completed in about 30 seconds, so that the scanned test piece does not cause more than 0.3% damage.
據上所述，本揭露檢測生化試片之裝置及方法，不但能呈現生化試片完整結構，且對於試片藥劑所造成的光污染程度極低，適合於產線快速對於所生產的試片進行檢測。According to the above, the apparatus and method for detecting a biochemical test strip can not only present the complete structure of the biochemical test strip, but also have a very low degree of light pollution caused by the test strip medicament, and is suitable for the production line to quickly perform on the produced test piece. Detection.
本新型創作雖以各種實施例揭露如上，然其並非用以限定本新型創作的範圍，任何所屬技術領域中具有通常知識者，在不脫離本新型創作之精神和範圍內，當可做些許的更動與潤飾。本新型創作之保護範圍當視後附之申請專利範圍所界定者為準。The present invention is disclosed in the above embodiments, but it is not intended to limit the scope of the novel creation, and any person having ordinary knowledge in the art can do a little while without departing from the spirit and scope of the novel creation. Change and retouch. The scope of protection of this new creation is subject to the definition of the scope of the patent application.
100‧‧‧光學檢測生化試片裝置100‧‧‧Optical detection biochemical test strip device
110‧‧‧控制單元110‧‧‧Control unit
112‧‧‧人機介面112‧‧‧Human Machine Interface
114‧‧‧主控電腦114‧‧‧Master computer
116‧‧‧資料處理器116‧‧‧ Data Processor
120‧‧‧掃描單元120‧‧‧ scan unit
122‧‧‧光源器122‧‧‧Light source
124‧‧‧影像處理器124‧‧‧Image Processor
126‧‧‧可調平台126‧‧‧Adjustable platform
130‧‧‧傳動標註單元130‧‧‧Transmission marking unit
132‧‧‧傳送機構132‧‧‧Transportation agency
134‧‧‧標註機134‧‧‧Marking machine
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI724484B (en) * | 2019-08-02 | 2021-04-11 | 國立勤益科技大學 | Rapid screen detection device |
| TWI799787B (en) * | 2021-02-08 | 2023-04-21 | 緯創資通股份有限公司 | Detecting method |
| TWI812161B (en) * | 2021-04-16 | 2023-08-11 | 由田新技股份有限公司 | Integrated optical inspection apparatus |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI724484B (en) * | 2019-08-02 | 2021-04-11 | 國立勤益科技大學 | Rapid screen detection device |
| TWI799787B (en) * | 2021-02-08 | 2023-04-21 | 緯創資通股份有限公司 | Detecting method |
| US11847782B2 (en) | 2021-02-08 | 2023-12-19 | Wistron Corporation | Detecting method |
| TWI812161B (en) * | 2021-04-16 | 2023-08-11 | 由田新技股份有限公司 | Integrated optical inspection apparatus |
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