TWI504611B - Hyaluronic acid and / or a salt thereof - Google Patents

Hyaluronic acid and / or a salt thereof Download PDF

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Publication number
TWI504611B
TWI504611B TW100109189A TW100109189A TWI504611B TW I504611 B TWI504611 B TW I504611B TW 100109189 A TW100109189 A TW 100109189A TW 100109189 A TW100109189 A TW 100109189A TW I504611 B TWI504611 B TW I504611B
Authority
TW
Taiwan
Prior art keywords
hyaluronic acid
molecular weight
ultrafiltration membrane
salt
value
Prior art date
Application number
TW100109189A
Other languages
English (en)
Chinese (zh)
Other versions
TW201139463A (en
Inventor
Masanobu Kohsaka
Katsumi Ishige
Hiromitsu Hoshika
Haruko Sakai
Original Assignee
Denki Kagaku Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denki Kagaku Kogyo Kk filed Critical Denki Kagaku Kogyo Kk
Publication of TW201139463A publication Critical patent/TW201139463A/zh
Application granted granted Critical
Publication of TWI504611B publication Critical patent/TWI504611B/zh

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Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Sustainable Development (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TW100109189A 2010-03-17 2011-03-17 Hyaluronic acid and / or a salt thereof TWI504611B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2010/054598 WO2011114475A1 (ja) 2010-03-17 2010-03-17 ヒアルロン酸及び/又はその塩の精製方法

Publications (2)

Publication Number Publication Date
TW201139463A TW201139463A (en) 2011-11-16
TWI504611B true TWI504611B (zh) 2015-10-21

Family

ID=44648604

Family Applications (1)

Application Number Title Priority Date Filing Date
TW100109189A TWI504611B (zh) 2010-03-17 2011-03-17 Hyaluronic acid and / or a salt thereof

Country Status (5)

Country Link
JP (1) JP5713995B2 (ja)
KR (1) KR101638662B1 (ja)
CN (1) CN102812050B (ja)
TW (1) TWI504611B (ja)
WO (1) WO2011114475A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105237656A (zh) * 2015-10-30 2016-01-13 深圳市阳光之路生物材料科技有限公司 一种提纯透明质酸钠的方法
CN105837705A (zh) * 2016-03-04 2016-08-10 冯翠军 一种去除透明质酸中热源的方法
CN105949478B (zh) * 2016-05-05 2021-10-01 宜昌东阳光生化制药有限公司 除去交联透明质酸中交联剂的方法
IT201700081449A1 (it) * 2017-07-18 2019-01-18 Fidia Farm Spa Procedimento di purificazione dell'acido ialuronico
JPWO2023219171A1 (ja) * 2022-05-13 2023-11-16

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04158796A (ja) * 1990-10-23 1992-06-01 Chisso Corp ヒアルロン酸ナトリウム水溶液の製造法
US6489467B1 (en) * 1999-01-28 2002-12-03 Chemedica S.A. Process for purifying high molecular weight hyaluronic acid
US20100137579A1 (en) * 2008-12-01 2010-06-03 Sustineo Biotechnology Co., Ltd. Process for purifying medical grade hyaluronic acid
CN103319627A (zh) * 2013-07-10 2013-09-25 南宁中诺生物工程有限责任公司 一种对透明质酸钠进行分子量分级的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6467196A (en) * 1987-09-08 1989-03-13 Yakult Honsha Kk Production of hyaluronic acid and strain used therefor
JP2728542B2 (ja) 1990-05-07 1998-03-18 株式会社日立製作所 同時2軸延伸装置のリンク過負荷検出装置
JPH09324001A (ja) 1996-04-02 1997-12-16 Kyowa Hakko Kogyo Co Ltd ヒアルロン酸ナトリウムの精製法
JP4151092B2 (ja) * 1997-10-22 2008-09-17 チッソ株式会社 オリゴヒアルロン酸もしくはその塩の製造法
KR101509139B1 (ko) * 2006-11-23 2015-04-08 주식회사 엘지생명과학 히알루론산의 정제방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04158796A (ja) * 1990-10-23 1992-06-01 Chisso Corp ヒアルロン酸ナトリウム水溶液の製造法
US6489467B1 (en) * 1999-01-28 2002-12-03 Chemedica S.A. Process for purifying high molecular weight hyaluronic acid
US20100137579A1 (en) * 2008-12-01 2010-06-03 Sustineo Biotechnology Co., Ltd. Process for purifying medical grade hyaluronic acid
CN103319627A (zh) * 2013-07-10 2013-09-25 南宁中诺生物工程有限责任公司 一种对透明质酸钠进行分子量分级的方法

Also Published As

Publication number Publication date
KR20130056222A (ko) 2013-05-29
TW201139463A (en) 2011-11-16
KR101638662B1 (ko) 2016-07-11
JPWO2011114475A1 (ja) 2013-06-27
CN102812050B (zh) 2016-01-20
JP5713995B2 (ja) 2015-05-07
WO2011114475A1 (ja) 2011-09-22
CN102812050A (zh) 2012-12-05

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