TW200738717A - Manufacturing method of carbapenem derivative by continuous reaction - Google Patents
Manufacturing method of carbapenem derivative by continuous reactionInfo
- Publication number
- TW200738717A TW200738717A TW095130335A TW95130335A TW200738717A TW 200738717 A TW200738717 A TW 200738717A TW 095130335 A TW095130335 A TW 095130335A TW 95130335 A TW95130335 A TW 95130335A TW 200738717 A TW200738717 A TW 200738717A
- Authority
- TW
- Taiwan
- Prior art keywords
- compound
- iii
- protecting group
- manufacturing
- continuous reaction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005238243A JP2008303143A (ja) | 2005-08-19 | 2005-08-19 | 連続化反応によるカルバぺネム誘導体の製法 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200738717A true TW200738717A (en) | 2007-10-16 |
Family
ID=37757617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095130335A TW200738717A (en) | 2005-08-19 | 2006-08-18 | Manufacturing method of carbapenem derivative by continuous reaction |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP2008303143A (zh) |
TW (1) | TW200738717A (zh) |
WO (1) | WO2007020960A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7932381B2 (en) * | 2005-02-15 | 2011-04-26 | Shionogi & Co., Ltd. | Process for producing carbapenem derivative and intermediate crystal therefor |
CN101613351B (zh) * | 2008-06-24 | 2011-10-19 | 上海医药工业研究院 | 多尼培南中间体的甲醇溶剂合物及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0699434B2 (ja) * | 1980-05-01 | 1994-12-07 | メルク エンド カムパニー インコーポレーテッド | 4−アリルアゼチジノンを経由する1−カルバペネム類の中間体の製造方法 |
JPS57123182A (en) * | 1980-12-18 | 1982-07-31 | Merck & Co Inc | 6- and 4-substituted-1-azabicyclo(3,1,2,0)heptane- 3,7-dione-2-carboxylate |
JPS6425779A (en) * | 1987-04-11 | 1989-01-27 | Lederle Japan Ltd | (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative |
US5317016A (en) * | 1991-08-20 | 1994-05-31 | Shionogi Seiyaku Kabushiki Kaisha | Pyrrolidylthiocarbapenem derivative |
JP3479720B2 (ja) * | 1992-07-08 | 2003-12-15 | 武田薬品工業株式会社 | カルバペネム類の製造法 |
GB9324725D0 (en) * | 1993-12-02 | 1994-01-19 | Fujisawa Pharmaceutical Co | Ficyclic compounds and preparation thereof |
JP4274739B2 (ja) * | 2001-05-10 | 2009-06-10 | 塩野義製薬株式会社 | アセチルチオピロリジン誘導体の製法 |
-
2005
- 2005-08-19 JP JP2005238243A patent/JP2008303143A/ja active Pending
-
2006
- 2006-08-17 WO PCT/JP2006/316140 patent/WO2007020960A1/ja active Application Filing
- 2006-08-18 TW TW095130335A patent/TW200738717A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007020960A1 (ja) | 2007-02-22 |
JP2008303143A (ja) | 2008-12-18 |
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