TR201908138T4 - Bir anti-her2 antikoru ilaç konjügatı ve bir bcl-2 inhibitörü ile kombinasyon terapisi. - Google Patents

Bir anti-her2 antikoru ilaç konjügatı ve bir bcl-2 inhibitörü ile kombinasyon terapisi. Download PDF

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Publication number
TR201908138T4
TR201908138T4 TR2019/08138T TR201908138T TR201908138T4 TR 201908138 T4 TR201908138 T4 TR 201908138T4 TR 2019/08138 T TR2019/08138 T TR 2019/08138T TR 201908138 T TR201908138 T TR 201908138T TR 201908138 T4 TR201908138 T4 TR 201908138T4
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TR
Turkey
Prior art keywords
inhibitor
combination therapy
drug conjugate
bcl
her2 antibody
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Application number
TR2019/08138T
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English (en)
Inventor
Lewis Phillips Gail
Sampath Deepak
Wertz Ingrid
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Hoffmann La Roche
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Publication date
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Publication of TR201908138T4 publication Critical patent/TR201908138T4/tr

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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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Abstract

Mevcut buluş, kanserden muzdarip bir hastanın, özellikle bir HER2 eksprese edici kanseri olan bir hastanın tedavisi için bir anti-HER2 antikor-ilaç konjugatını ve seçici bir Bcl-2 inhibitörünü içeren bir kombinasyon terapisine yöneliktir,
TR2019/08138T 2015-07-07 2016-07-06 Bir anti-her2 antikoru ilaç konjügatı ve bir bcl-2 inhibitörü ile kombinasyon terapisi. TR201908138T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562189610P 2015-07-07 2015-07-07

Publications (1)

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TR201908138T4 true TR201908138T4 (tr) 2019-06-21

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ID=56464320

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TR2019/08138T TR201908138T4 (tr) 2015-07-07 2016-07-06 Bir anti-her2 antikoru ilaç konjügatı ve bir bcl-2 inhibitörü ile kombinasyon terapisi.

Country Status (21)

Country Link
US (2) US10898570B2 (tr)
EP (1) EP3319995B1 (tr)
JP (2) JP6910339B2 (tr)
KR (1) KR20180021060A (tr)
CN (2) CN113607945A (tr)
AU (1) AU2016290065B2 (tr)
BR (1) BR112017028012A2 (tr)
CA (1) CA2990465A1 (tr)
DK (1) DK3319995T3 (tr)
ES (1) ES2731377T3 (tr)
HR (1) HRP20191019T1 (tr)
HU (1) HUE044139T2 (tr)
IL (1) IL256451B (tr)
LT (1) LT3319995T (tr)
MX (1) MX2018000135A (tr)
PL (1) PL3319995T3 (tr)
PT (1) PT3319995T (tr)
RS (1) RS58823B1 (tr)
SI (1) SI3319995T1 (tr)
TR (1) TR201908138T4 (tr)
WO (1) WO2017007846A1 (tr)

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LT3319995T (lt) 2019-07-10
EP3319995B1 (en) 2019-04-17
PT3319995T (pt) 2019-06-14
US10898570B2 (en) 2021-01-26
RS58823B1 (sr) 2019-07-31
JP2021178825A (ja) 2021-11-18
US20210213130A1 (en) 2021-07-15
AU2016290065A1 (en) 2018-01-18
BR112017028012A2 (pt) 2018-08-28
PL3319995T3 (pl) 2019-09-30
US20180140700A1 (en) 2018-05-24
CN107922504A (zh) 2018-04-17
HRP20191019T1 (hr) 2019-09-06
CN107922504B (zh) 2021-07-30
IL256451B (en) 2021-12-01
HUE044139T2 (hu) 2019-09-30
AU2016290065B2 (en) 2022-08-11
ES2731377T3 (es) 2019-11-15
JP2018521064A (ja) 2018-08-02
CN113607945A (zh) 2021-11-05
EP3319995A1 (en) 2018-05-16
CA2990465A1 (en) 2017-01-12
IL256451A (en) 2018-02-28
MX2018000135A (es) 2018-03-23
WO2017007846A1 (en) 2017-01-12
KR20180021060A (ko) 2018-02-28
JP6910339B2 (ja) 2021-07-28
DK3319995T3 (da) 2019-06-24
SI3319995T1 (sl) 2019-07-31

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