TR200102572T2 - Eritromisin türevleri. - Google Patents
Eritromisin türevleri.Info
- Publication number
- TR200102572T2 TR200102572T2 TR2001/02572T TR200102572T TR200102572T2 TR 200102572 T2 TR200102572 T2 TR 200102572T2 TR 2001/02572 T TR2001/02572 T TR 2001/02572T TR 200102572 T TR200102572 T TR 200102572T TR 200102572 T2 TR200102572 T2 TR 200102572T2
- Authority
- TR
- Turkey
- Prior art keywords
- group
- substituted
- substituent
- alkyl
- aralkyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Asagidaki genel formül ile temsil edilen bir eritromisin türevi veya bunun bir tuzu (FORMÜL) buradaki R, bir hidrojen atomunu veya bir alt alkil grubunu temsil eder; R1, ikame edilebilen bir C5-12 alkil grubunu, ikame edilebilen bir sikloalkil grubunu, ikame edilebilen bir (sikloalkil)alkil grubunu, ikame edilebilen bir aralkil grubunu veya-(CH2)n-X-R4 ile temsil edilen bir grubu temsil eder; R2, bir hidrojen atomunu veya bir asetil grubunu temsil eder; R3, ikame edilebilen bir asil grubunu veya-C(=O)-Y-R5 formülü ile temsil edilen bir grubu temsil eder; R4, ikame edilebilen bir alkil grubunu, ikame edilebilen bir alkoksialkil grubunu, ikame edilebilen bir alkiltiyoalkil grubunu, ikame edilebilen bir alkilaminoalkil grubunu, ikame bir aralkil grubunu temsil eder; R5 ikame edilbilen bir alkil grubunu veya ikame edilebilen bir aralkil grubunu temsil eder; n, 1 ila 6 arasinda bir integeri temsil eder; (DEVAMI VAR).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10072699 | 1999-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200102572T2 true TR200102572T2 (tr) | 2002-02-21 |
Family
ID=14281635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/02572T TR200102572T2 (tr) | 1999-04-08 | 2000-04-06 | Eritromisin türevleri. |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1167375A4 (tr) |
| KR (1) | KR20020007333A (tr) |
| CN (1) | CN1343216A (tr) |
| AR (1) | AR023264A1 (tr) |
| AU (1) | AU3671000A (tr) |
| BG (1) | BG105919A (tr) |
| BR (1) | BR0010518A (tr) |
| CA (1) | CA2367319A1 (tr) |
| CZ (1) | CZ20013497A3 (tr) |
| HK (1) | HK1045697A1 (tr) |
| HU (1) | HUP0201116A3 (tr) |
| IL (1) | IL145256A0 (tr) |
| NO (1) | NO20014362L (tr) |
| NZ (1) | NZ513998A (tr) |
| PL (1) | PL354409A1 (tr) |
| SK (1) | SK13972001A3 (tr) |
| TR (1) | TR200102572T2 (tr) |
| WO (1) | WO2000061593A1 (tr) |
| ZA (1) | ZA200107346B (tr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1259923B1 (en) * | 2000-02-24 | 2005-12-14 | Abbott Laboratories | Anti-infective agents useful against mulitidrug-resistant strains of bacteria |
| US6946446B2 (en) | 2000-02-24 | 2005-09-20 | Abbott Laboratories | Anti-infective agents useful against multidrug-resistant strains of bacteria |
| JP2002173498A (ja) * | 2000-09-27 | 2002-06-21 | Hokuriku Seiyaku Co Ltd | エリスロマイシン誘導体 |
| PE20030438A1 (es) * | 2001-09-05 | 2003-07-03 | Hokuriku Pharmaceutical | Medicamento que comprende un derivado de eritromicina como agente antituberculoso |
| WO2004080391A2 (en) | 2003-03-10 | 2004-09-23 | Optimer Pharmaceuticals, Inc. | Novel antibacterial agents |
| WO2004108744A2 (en) * | 2003-05-19 | 2004-12-16 | Prasad K Deshpande | Azalides and azaketolides having antimicrobial activity |
| JP2008540503A (ja) | 2005-05-10 | 2008-11-20 | グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ | 細菌感染症の処置に有用なエーテル結合マクロライド |
| US9453042B2 (en) | 2007-10-25 | 2016-09-27 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| WO2010048600A1 (en) | 2008-10-24 | 2010-04-29 | Cempra Pharmaceuticals, Inc. | Methods for treating resistant diseases using triazole containing macrolides |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| WO2011032052A1 (en) | 2009-09-10 | 2011-03-17 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and mac diseases |
| EP2571506B1 (en) * | 2010-05-20 | 2017-05-10 | Cempra Pharmaceuticals, Inc. | Processes for preparing macrolides and ketolides and intermediates therefor |
| WO2012034058A1 (en) | 2010-09-10 | 2012-03-15 | Cempra Pharmaceuticals, Inc. | Hydrogen bond forming fluoro ketolides for treating diseases |
| RU2658050C2 (ru) | 2012-03-27 | 2018-06-19 | Семпра Фармасьютикалз, Инк. | Парентеральные составы для введения макролидных антибиотиков |
| AU2014239959A1 (en) | 2013-03-14 | 2015-10-01 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| US9751908B2 (en) | 2013-03-15 | 2017-09-05 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
| AU2014252462A1 (en) * | 2013-04-10 | 2015-10-01 | Probiotic Pharmaceuticals Aps | Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK109886A (da) * | 1985-03-12 | 1986-09-13 | Beecham Group Plc | Erythromycinderivater |
| GB8506380D0 (en) * | 1985-03-12 | 1985-04-11 | Beecham Group Plc | Chemical compounds |
| US5302705A (en) * | 1989-10-07 | 1994-04-12 | Taisho Pharmaceutical Co., Ltd. | 6-O-methylerythromycin a oxime derivatives |
| US5719272A (en) * | 1996-04-02 | 1998-02-17 | Abbott Laboratories | 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives |
| EP0895999A1 (en) * | 1997-08-06 | 1999-02-10 | Pfizer Products Inc. | C-4" substituted macrolide antibiotics |
-
2000
- 2000-04-05 AR ARP000101551A patent/AR023264A1/es unknown
- 2000-04-06 SK SK1397-2001A patent/SK13972001A3/sk unknown
- 2000-04-06 CN CN00805014A patent/CN1343216A/zh active Pending
- 2000-04-06 EP EP20000915372 patent/EP1167375A4/en not_active Withdrawn
- 2000-04-06 NZ NZ513998A patent/NZ513998A/xx not_active Application Discontinuation
- 2000-04-06 WO PCT/JP2000/002226 patent/WO2000061593A1/ja active Application Filing
- 2000-04-06 HU HU0201116A patent/HUP0201116A3/hu unknown
- 2000-04-06 BR BR0010518-0A patent/BR0010518A/pt not_active IP Right Cessation
- 2000-04-06 TR TR2001/02572T patent/TR200102572T2/tr unknown
- 2000-04-06 CZ CZ20013497A patent/CZ20013497A3/cs unknown
- 2000-04-06 IL IL14525600A patent/IL145256A0/xx unknown
- 2000-04-06 KR KR1020017011771A patent/KR20020007333A/ko not_active Application Discontinuation
- 2000-04-06 PL PL00354409A patent/PL354409A1/xx unknown
- 2000-04-06 AU AU36710/00A patent/AU3671000A/en not_active Abandoned
- 2000-04-06 CA CA002367319A patent/CA2367319A1/en not_active Abandoned
-
2001
- 2001-09-05 ZA ZA200107346A patent/ZA200107346B/xx unknown
- 2001-09-07 NO NO20014362A patent/NO20014362L/no not_active Application Discontinuation
- 2001-09-19 BG BG105919A patent/BG105919A/xx unknown
-
2002
- 2002-09-30 HK HK02107210.7A patent/HK1045697A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK13972001A3 (sk) | 2002-08-06 |
| HUP0201116A3 (en) | 2003-03-28 |
| AR023264A1 (es) | 2002-09-04 |
| KR20020007333A (ko) | 2002-01-26 |
| WO2000061593A1 (fr) | 2000-10-19 |
| HUP0201116A2 (en) | 2002-08-28 |
| NO20014362D0 (no) | 2001-09-07 |
| NO20014362L (no) | 2001-12-04 |
| CZ20013497A3 (cs) | 2002-05-15 |
| EP1167375A4 (en) | 2002-10-30 |
| ZA200107346B (en) | 2002-11-27 |
| CN1343216A (zh) | 2002-04-03 |
| IL145256A0 (en) | 2002-06-30 |
| BR0010518A (pt) | 2002-01-08 |
| AU3671000A (en) | 2000-11-14 |
| PL354409A1 (en) | 2004-01-12 |
| NZ513998A (en) | 2001-09-28 |
| EP1167375A1 (en) | 2002-01-02 |
| CA2367319A1 (en) | 2000-10-19 |
| BG105919A (en) | 2002-06-28 |
| HK1045697A1 (zh) | 2002-12-06 |
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