TR199800436A2 - Primidin türevlerinin kanserin önlenmesi için kullanilmasi. - Google Patents

Primidin türevlerinin kanserin önlenmesi için kullanilmasi.

Info

Publication number
TR199800436A2
TR199800436A2 TR1998/00436A TR9800436A TR199800436A2 TR 199800436 A2 TR199800436 A2 TR 199800436A2 TR 1998/00436 A TR1998/00436 A TR 1998/00436A TR 9800436 A TR9800436 A TR 9800436A TR 199800436 A2 TR199800436 A2 TR 199800436A2
Authority
TR
Turkey
Prior art keywords
pyrimidine derivatives
cancer prevention
prevention
cancer
salts
Prior art date
Application number
TR1998/00436A
Other languages
English (en)
Other versions
TR199800436A3 (tr
Inventor
Karl Geisen Dr.
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of TR199800436A3 publication Critical patent/TR199800436A3/tr
Publication of TR199800436A2 publication Critical patent/TR199800436A2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Yukaridaki bulus, pirimidin türevlerinin kanser hastaliklarinin önlenmesi için kullanilmasiyla ilgilidir. Kullanilan pirimidin türevleri, içinde R1 ile R7 arasindakilerin anlami belirtildigi gibi olan formül I'in etki maddeleri ile birlikte, bunlarin fizyolojik açisindan zararsiz olan tuzlaridir.
TR1998/00436A 1997-03-13 1998-03-11 Primidin türevlerinin kanserin önlenmesi için kullanilmasi. TR199800436A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19710435A DE19710435A1 (de) 1997-03-13 1997-03-13 Verwendung von Pyrimidinderivaten zur Prävention von Krebs allein oder in Kombination mit anderen therapeutischen Maßnahmen

Publications (2)

Publication Number Publication Date
TR199800436A3 TR199800436A3 (tr) 1998-10-21
TR199800436A2 true TR199800436A2 (tr) 1998-10-21

Family

ID=7823277

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00436A TR199800436A2 (tr) 1997-03-13 1998-03-11 Primidin türevlerinin kanserin önlenmesi için kullanilmasi.

Country Status (19)

Country Link
US (1) US6156755A (tr)
EP (1) EP0864327B1 (tr)
JP (1) JPH10279482A (tr)
KR (1) KR19980080148A (tr)
CN (1) CN1193513A (tr)
AR (1) AR011190A1 (tr)
AT (1) ATE227129T1 (tr)
AU (1) AU726089B2 (tr)
BR (1) BR9800884A (tr)
CA (1) CA2231765A1 (tr)
CZ (1) CZ74698A3 (tr)
DE (2) DE19710435A1 (tr)
DK (1) DK0864327T3 (tr)
ES (1) ES2182161T3 (tr)
HU (1) HUP9800535A1 (tr)
PL (1) PL325327A1 (tr)
PT (1) PT864327E (tr)
RU (1) RU2209629C2 (tr)
TR (1) TR199800436A2 (tr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE336484T1 (de) 1998-08-29 2006-09-15 Astrazeneca Ab Pyrimidine verbindungen
DE69933680T2 (de) 1998-08-29 2007-08-23 Astrazeneca Ab Pyrimidine verbindungen
GB9828511D0 (en) 1998-12-24 1999-02-17 Zeneca Ltd Chemical compounds
GB9905075D0 (en) 1999-03-06 1999-04-28 Zeneca Ltd Chemical compounds
GB9907658D0 (en) 1999-04-06 1999-05-26 Zeneca Ltd Chemical compounds
GB9919778D0 (en) 1999-08-21 1999-10-27 Zeneca Ltd Chemical compounds
GB0004886D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004888D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004887D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004890D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0007371D0 (en) 2000-03-28 2000-05-17 Astrazeneca Uk Ltd Chemical compounds
GB0016877D0 (en) 2000-07-11 2000-08-30 Astrazeneca Ab Chemical compounds
GB0021726D0 (en) 2000-09-05 2000-10-18 Astrazeneca Ab Chemical compounds
US6716851B2 (en) * 2000-12-12 2004-04-06 Cytovia, Inc. Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof
GB0103926D0 (en) 2001-02-17 2001-04-04 Astrazeneca Ab Chemical compounds
GB0113041D0 (en) 2001-05-30 2001-07-18 Astrazeneca Ab Chemical compounds
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
GB0205688D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
GB0205693D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
WO2003076434A1 (en) 2002-03-09 2003-09-18 Astrazeneca Ab 4- imidazolyl substuited pyrimidine derivatives with cdk inhibitiory activity
GB0205690D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
RU2376992C2 (ru) * 2002-07-29 2009-12-27 Райджел Фармасьютикалз, Инк. Способы лечения или профилактики аутоиммунных заболеваний с помощью соединений 2,4-пиримидиндиамина
MXPA05001096A (es) * 2002-07-29 2005-11-23 Rigel Pharmaceuticals Inc Metodos para tratamiento o prevencion de enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina.
GB0311274D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0311276D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0323137D0 (en) * 2003-10-03 2003-11-05 Chang Lisa C W 2,4,6- Trisubstituted pyrimidines and their different uses
US20080058356A1 (en) * 2003-12-15 2008-03-06 Neurocrine Biosciences, Inc. 2,6 Bisheteroaryl-4-Aminopyrimidines as Adenosine Receptor Antagonists
TW200528101A (en) 2004-02-03 2005-09-01 Astrazeneca Ab Chemical compounds
EP1888565B1 (en) * 2005-04-11 2011-03-23 Almirall, S.A. 2, 6-di (hetero) aryl -4-amido-pyrimidines as adenosine receptor antagonists
US20060293343A1 (en) * 2005-05-18 2006-12-28 Asahi Kasei Pharma Corporation Pyrimidine derivatives
EP1934213A1 (en) 2005-09-30 2008-06-25 Astra Zeneca AB Imidazo [1,2-a] pyridine having anti-cell-proliferation activity
WO2008070661A1 (en) * 2006-12-04 2008-06-12 Neurocrine Biosciences, Inc. Substituted pyrimidines as adenosine receptor antagonists
US20100249084A1 (en) * 2007-03-21 2010-09-30 Youngsheng Chen Substituted pyrimidines as adenosine receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3905364A1 (de) * 1989-02-22 1990-08-23 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool
DE4025387A1 (de) * 1990-08-10 1992-02-13 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als reagenzien
AU683620B2 (en) * 1992-09-28 1997-11-20 Pfizer Inc. Substituted pyrimidines for control of diabetic complications

Also Published As

Publication number Publication date
EP0864327A1 (de) 1998-09-16
DE19710435A1 (de) 1998-09-17
KR19980080148A (ko) 1998-11-25
RU2209629C2 (ru) 2003-08-10
ES2182161T3 (es) 2003-03-01
US6156755A (en) 2000-12-05
CN1193513A (zh) 1998-09-23
DE59806139D1 (de) 2002-12-12
HUP9800535A1 (hu) 2000-11-28
HU9800535D0 (en) 1998-04-28
CA2231765A1 (en) 1998-09-13
CZ74698A3 (cs) 1998-09-16
PT864327E (pt) 2003-03-31
EP0864327B1 (de) 2002-11-06
PL325327A1 (en) 1998-09-14
AU5835098A (en) 1998-09-17
TR199800436A3 (tr) 1998-10-21
ATE227129T1 (de) 2002-11-15
DK0864327T3 (da) 2003-02-17
AR011190A1 (es) 2000-08-02
BR9800884A (pt) 1999-12-07
AU726089B2 (en) 2000-11-02
JPH10279482A (ja) 1998-10-20

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