TNSN08196A1 - Derives de pyrazine - Google Patents
Derives de pyrazineInfo
- Publication number
- TNSN08196A1 TNSN08196A1 TNP2008000196A TNSN08196A TNSN08196A1 TN SN08196 A1 TNSN08196 A1 TN SN08196A1 TN P2008000196 A TNP2008000196 A TN P2008000196A TN SN08196 A TNSN08196 A TN SN08196A TN SN08196 A1 TNSN08196 A1 TN SN08196A1
- Authority
- TN
- Tunisia
- Prior art keywords
- des
- composés
- préparer
- pour les
- les
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La présente invention concerne des composés de formule (I), des sels et solvates de ceux-ci, acceptables d'un point de vue pharmaceutique, des procédés pour les préparer, des produits intermédiaires utilisés pour les préparer, des compositions contenant ces composés, ainsi que les utilisations de tels composés dans le traitement de la douleur.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73366205P | 2005-11-04 | 2005-11-04 | |
PCT/IB2006/003055 WO2007052123A2 (fr) | 2005-11-04 | 2006-10-23 | Derives de pyrazine |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN08196A1 true TNSN08196A1 (fr) | 2009-10-30 |
Family
ID=37890558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNP2008000196A TNSN08196A1 (fr) | 2005-11-04 | 2008-05-02 | Derives de pyrazine |
Country Status (27)
Country | Link |
---|---|
US (1) | US7572797B2 (fr) |
EP (1) | EP1945630B1 (fr) |
JP (1) | JP2009514937A (fr) |
KR (1) | KR20080066073A (fr) |
CN (1) | CN101356169A (fr) |
AP (1) | AP2008004468A0 (fr) |
AR (1) | AR057855A1 (fr) |
AT (1) | ATE525372T1 (fr) |
AU (1) | AU2006310215A1 (fr) |
BR (1) | BRPI0618129A2 (fr) |
CA (1) | CA2624621C (fr) |
CR (1) | CR9954A (fr) |
DO (1) | DOP2006000243A (fr) |
EA (1) | EA200801011A1 (fr) |
EC (1) | ECSP088412A (fr) |
ES (1) | ES2371932T3 (fr) |
GT (1) | GT200600475A (fr) |
IL (1) | IL191059A0 (fr) |
MA (1) | MA29926B1 (fr) |
NL (1) | NL2000284C2 (fr) |
NO (1) | NO20082496L (fr) |
PE (1) | PE20070715A1 (fr) |
TN (1) | TNSN08196A1 (fr) |
TW (1) | TW200804353A (fr) |
UY (1) | UY29893A1 (fr) |
WO (1) | WO2007052123A2 (fr) |
ZA (1) | ZA200803671B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998003167A1 (fr) | 1996-07-24 | 1998-01-29 | Warner-Lambert Company | Isobutylgaba et ses derives utilises pour le traitement de la douleur |
EP1741708A1 (fr) * | 2005-06-28 | 2007-01-10 | Sanofi-Aventis Deutschland GmbH | Amides heterocycliques substitués contenant un linker cyclique ou insaturé, et leur utilisation comme agent pharmaceutique |
GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
CA2685952C (fr) * | 2007-05-03 | 2012-03-13 | Pfizer Limited | Derives de pyrazine |
ES2398606T3 (es) | 2007-05-03 | 2013-03-20 | Pfizer Limited | Derivados de 2-piridin-carboxamida como moduladores de los canales de sodio |
WO2009026434A1 (fr) * | 2007-08-21 | 2009-02-26 | Alkermes, Inc. | Formulations pharmaceutiques pulmonaires |
NZ585789A (en) | 2007-12-10 | 2012-03-30 | Novartis Ag | Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel |
US20100331310A1 (en) | 2008-02-13 | 2010-12-30 | Fumihiro Ozaki | Bicycloamine derivatives |
SG190667A1 (en) | 2008-05-23 | 2013-06-28 | Panmira Pharmaceuticals Llc | 5-lipoxygenase-activating protein inhibitor |
US8546431B2 (en) | 2008-10-01 | 2013-10-01 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
US9856240B2 (en) * | 2011-10-19 | 2018-01-02 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
EP2841435B1 (fr) * | 2012-04-25 | 2017-09-06 | RaQualia Pharma Inc. | Dérivés de pyrrolopyridinone en tant que bloquants des ttx-s |
TWI644899B (zh) | 2013-02-04 | 2018-12-21 | 健生藥品公司 | Flap調節劑 |
WO2014121055A2 (fr) | 2013-02-04 | 2014-08-07 | Janssen Pharmaceutica Nv | Modulateurs flap |
EP3193603A4 (fr) * | 2014-09-10 | 2018-02-28 | Epizyme, Inc. | Composés carboxamides isoxazoles |
BR112017018413B1 (pt) | 2015-02-27 | 2023-05-02 | CalciMedica, Inc | Uso de inibidores intracelulares de sinalização de cálcio no tratamento de pancreatite, composições e compostos relacionados |
US10478435B2 (en) | 2015-08-07 | 2019-11-19 | Calcimedica, Inc. | Use of CRAC channel inhibitors for the treatment of stroke and traumatic brain injury |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA26473A1 (fr) * | 1997-03-01 | 2004-12-20 | Glaxo Group Ltd | Composes pharmacologiquement actifs. |
DK1446387T3 (da) * | 2001-11-21 | 2009-12-21 | Pharmacia & Upjohn Co Llc | Substituerede aryl, 1,4-pyrazinderivater |
US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
KR20060123208A (ko) * | 2003-10-27 | 2006-12-01 | 아스테라스 세이야쿠 가부시키가이샤 | 피라진 유도체 및 이의 약학적 용도 |
ATE437864T1 (de) * | 2004-10-22 | 2009-08-15 | Janssen Pharmaceutica Nv | Aromatische amide als hemmer der c-fms-kinase |
-
2006
- 2006-10-20 NL NL2000284A patent/NL2000284C2/nl not_active IP Right Cessation
- 2006-10-23 ES ES06809149T patent/ES2371932T3/es active Active
- 2006-10-23 JP JP2008539517A patent/JP2009514937A/ja not_active Ceased
- 2006-10-23 BR BRPI0618129-5A patent/BRPI0618129A2/pt not_active IP Right Cessation
- 2006-10-23 AP AP2008004468A patent/AP2008004468A0/xx unknown
- 2006-10-23 CA CA2624621A patent/CA2624621C/fr not_active Expired - Fee Related
- 2006-10-23 EA EA200801011A patent/EA200801011A1/ru unknown
- 2006-10-23 KR KR1020087013403A patent/KR20080066073A/ko not_active Application Discontinuation
- 2006-10-23 EP EP06809149A patent/EP1945630B1/fr not_active Not-in-force
- 2006-10-23 AT AT06809149T patent/ATE525372T1/de not_active IP Right Cessation
- 2006-10-23 AU AU2006310215A patent/AU2006310215A1/en not_active Abandoned
- 2006-10-23 CN CNA2006800504914A patent/CN101356169A/zh active Pending
- 2006-10-23 WO PCT/IB2006/003055 patent/WO2007052123A2/fr active Search and Examination
- 2006-11-01 UY UY29893A patent/UY29893A1/es not_active Application Discontinuation
- 2006-11-02 GT GT200600475A patent/GT200600475A/es unknown
- 2006-11-02 AR ARP060104815A patent/AR057855A1/es unknown
- 2006-11-03 TW TW095140879A patent/TW200804353A/zh unknown
- 2006-11-03 PE PE2006001349A patent/PE20070715A1/es not_active Application Discontinuation
- 2006-11-03 US US11/556,354 patent/US7572797B2/en not_active Expired - Fee Related
- 2006-11-03 DO DO2006000243A patent/DOP2006000243A/es unknown
-
2008
- 2008-04-25 ZA ZA200803671A patent/ZA200803671B/xx unknown
- 2008-04-27 IL IL191059A patent/IL191059A0/en unknown
- 2008-04-29 EC EC2008008412A patent/ECSP088412A/es unknown
- 2008-05-02 TN TNP2008000196A patent/TNSN08196A1/fr unknown
- 2008-05-02 MA MA30893A patent/MA29926B1/fr unknown
- 2008-05-07 CR CR9954A patent/CR9954A/es not_active Application Discontinuation
- 2008-06-04 NO NO20082496A patent/NO20082496L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101356169A (zh) | 2009-01-28 |
ECSP088412A (es) | 2008-05-30 |
NL2000284C2 (nl) | 2007-09-28 |
EA200801011A1 (ru) | 2009-02-27 |
KR20080066073A (ko) | 2008-07-15 |
CA2624621C (fr) | 2010-11-30 |
UY29893A1 (es) | 2007-06-29 |
GT200600475A (es) | 2007-07-06 |
ZA200803671B (en) | 2009-03-25 |
WO2007052123A2 (fr) | 2007-05-10 |
CR9954A (es) | 2008-05-28 |
IL191059A0 (en) | 2008-12-29 |
ATE525372T1 (de) | 2011-10-15 |
MA29926B1 (fr) | 2008-11-03 |
US20070105872A1 (en) | 2007-05-10 |
WO2007052123A3 (fr) | 2007-07-12 |
PE20070715A1 (es) | 2007-08-11 |
US7572797B2 (en) | 2009-08-11 |
AR057855A1 (es) | 2007-12-19 |
NO20082496L (no) | 2008-07-24 |
CA2624621A1 (fr) | 2007-05-10 |
AP2008004468A0 (en) | 2008-06-30 |
EP1945630A2 (fr) | 2008-07-23 |
AU2006310215A1 (en) | 2007-05-10 |
JP2009514937A (ja) | 2009-04-09 |
ES2371932T3 (es) | 2012-01-11 |
EP1945630B1 (fr) | 2011-09-21 |
NL2000284A1 (nl) | 2007-05-07 |
BRPI0618129A2 (pt) | 2011-08-16 |
DOP2006000243A (es) | 2007-05-31 |
TW200804353A (en) | 2008-01-16 |
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