NO20082496L - Pyrazinderivater - Google Patents
PyrazinderivaterInfo
- Publication number
- NO20082496L NO20082496L NO20082496A NO20082496A NO20082496L NO 20082496 L NO20082496 L NO 20082496L NO 20082496 A NO20082496 A NO 20082496A NO 20082496 A NO20082496 A NO 20082496A NO 20082496 L NO20082496 L NO 20082496L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- pyrazine derivatives
- preparation
- solvates
- pain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
Foreliggende oppfinnelse angår forbindelser med formel (I): og farmasøytisk akseptable salter og solvater derav, fremgangsmåter for fremstillingen av, intermediater anvendt ved fremstillingen av, og sammensetninger som inneholder slike forbindelser og anvendelsene av slike forbindelser for behandlingen av smerte.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73366205P | 2005-11-04 | 2005-11-04 | |
PCT/IB2006/003055 WO2007052123A2 (en) | 2005-11-04 | 2006-10-23 | Pyrazine derivatives as sodium channel modulators for the treatment of pain |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082496L true NO20082496L (no) | 2008-07-24 |
Family
ID=37890558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082496A NO20082496L (no) | 2005-11-04 | 2008-06-04 | Pyrazinderivater |
Country Status (27)
Country | Link |
---|---|
US (1) | US7572797B2 (no) |
EP (1) | EP1945630B1 (no) |
JP (1) | JP2009514937A (no) |
KR (1) | KR20080066073A (no) |
CN (1) | CN101356169A (no) |
AP (1) | AP2008004468A0 (no) |
AR (1) | AR057855A1 (no) |
AT (1) | ATE525372T1 (no) |
AU (1) | AU2006310215A1 (no) |
BR (1) | BRPI0618129A2 (no) |
CA (1) | CA2624621C (no) |
CR (1) | CR9954A (no) |
DO (1) | DOP2006000243A (no) |
EA (1) | EA200801011A1 (no) |
EC (1) | ECSP088412A (no) |
ES (1) | ES2371932T3 (no) |
GT (1) | GT200600475A (no) |
IL (1) | IL191059A0 (no) |
MA (1) | MA29926B1 (no) |
NL (1) | NL2000284C2 (no) |
NO (1) | NO20082496L (no) |
PE (1) | PE20070715A1 (no) |
TN (1) | TNSN08196A1 (no) |
TW (1) | TW200804353A (no) |
UY (1) | UY29893A1 (no) |
WO (1) | WO2007052123A2 (no) |
ZA (1) | ZA200803671B (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI0934061T1 (en) | 1996-07-24 | 2003-10-31 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
EP1741708A1 (en) * | 2005-06-28 | 2007-01-10 | Sanofi-Aventis Deutschland GmbH | Heteroaryl-substituted amides comprising an unsaturated or cyclic linker group, and their use as pharmaceuticals |
US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
WO2008135826A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Limited | 2 -pyridine carboxamide derivatives as sodium channel modulators |
CA2685952C (en) * | 2007-05-03 | 2012-03-13 | Pfizer Limited | N- [6-amino-5- (phenyl) pyrazin-2-yl] -isoxazole-4-carboxamide derivatives and related compounds as nav1.8 channel modulators for the treatment of pain |
US8614255B2 (en) * | 2007-08-21 | 2013-12-24 | Civitas Therapeutics, Inc. | Pulmonary pharmaceutical formulations |
PE20091096A1 (es) | 2007-12-10 | 2009-08-25 | Novartis Ag | Compuestos organicos |
US8252810B2 (en) | 2008-02-13 | 2012-08-28 | Eisai R&D Management Co., Ltd. | Bicycloamine derivatives |
WO2010068311A1 (en) | 2008-05-23 | 2010-06-17 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein inhibitor |
US8546431B2 (en) | 2008-10-01 | 2013-10-01 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
US9856240B2 (en) * | 2011-10-19 | 2018-01-02 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
US9187475B2 (en) * | 2012-04-25 | 2015-11-17 | Raqualia Pharma Inc. | Pyrrolopyridinone derivatives as TTX-S blockers |
TWI644899B (zh) * | 2013-02-04 | 2018-12-21 | 健生藥品公司 | Flap調節劑 |
US9745328B2 (en) | 2013-02-04 | 2017-08-29 | Janssen Pharmaceutica Nv | Flap modulators |
AU2015315167A1 (en) * | 2014-09-10 | 2017-03-16 | Epizyme, Inc. | Isoxazole carboxamide compounds |
AR103807A1 (es) | 2015-02-27 | 2017-06-07 | Calcimedica Inc | Tratamiento de la pancreatitis |
WO2017027400A1 (en) * | 2015-08-07 | 2017-02-16 | Calcimedica, Inc. | Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA26473A1 (fr) * | 1997-03-01 | 2004-12-20 | Glaxo Group Ltd | Composes pharmacologiquement actifs. |
BR0214309A (pt) * | 2001-11-21 | 2004-10-13 | Upjohn Co | Derivados aril-1,4-pirazina substituìdos |
US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
BRPI0415863A (pt) * | 2003-10-27 | 2007-01-09 | Astellas Pharma Inc | derivados pirazina e seus usos farmacêuticos |
JP5008569B2 (ja) * | 2004-10-22 | 2012-08-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | C−fmsキナーゼのインヒビターとしての芳香族アミド |
-
2006
- 2006-10-20 NL NL2000284A patent/NL2000284C2/nl not_active IP Right Cessation
- 2006-10-23 ES ES06809149T patent/ES2371932T3/es active Active
- 2006-10-23 CN CNA2006800504914A patent/CN101356169A/zh active Pending
- 2006-10-23 CA CA2624621A patent/CA2624621C/en not_active Expired - Fee Related
- 2006-10-23 JP JP2008539517A patent/JP2009514937A/ja not_active Ceased
- 2006-10-23 BR BRPI0618129-5A patent/BRPI0618129A2/pt not_active IP Right Cessation
- 2006-10-23 KR KR1020087013403A patent/KR20080066073A/ko not_active Application Discontinuation
- 2006-10-23 EA EA200801011A patent/EA200801011A1/ru unknown
- 2006-10-23 AU AU2006310215A patent/AU2006310215A1/en not_active Abandoned
- 2006-10-23 AP AP2008004468A patent/AP2008004468A0/xx unknown
- 2006-10-23 WO PCT/IB2006/003055 patent/WO2007052123A2/en active Search and Examination
- 2006-10-23 EP EP06809149A patent/EP1945630B1/en not_active Not-in-force
- 2006-10-23 AT AT06809149T patent/ATE525372T1/de not_active IP Right Cessation
- 2006-11-01 UY UY29893A patent/UY29893A1/es not_active Application Discontinuation
- 2006-11-02 AR ARP060104815A patent/AR057855A1/es unknown
- 2006-11-02 GT GT200600475A patent/GT200600475A/es unknown
- 2006-11-03 PE PE2006001349A patent/PE20070715A1/es not_active Application Discontinuation
- 2006-11-03 DO DO2006000243A patent/DOP2006000243A/es unknown
- 2006-11-03 TW TW095140879A patent/TW200804353A/zh unknown
- 2006-11-03 US US11/556,354 patent/US7572797B2/en not_active Expired - Fee Related
-
2008
- 2008-04-25 ZA ZA200803671A patent/ZA200803671B/xx unknown
- 2008-04-27 IL IL191059A patent/IL191059A0/en unknown
- 2008-04-29 EC EC2008008412A patent/ECSP088412A/es unknown
- 2008-05-02 TN TNP2008000196A patent/TNSN08196A1/fr unknown
- 2008-05-02 MA MA30893A patent/MA29926B1/fr unknown
- 2008-05-07 CR CR9954A patent/CR9954A/es not_active Application Discontinuation
- 2008-06-04 NO NO20082496A patent/NO20082496L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CR9954A (es) | 2008-05-28 |
CN101356169A (zh) | 2009-01-28 |
TNSN08196A1 (fr) | 2009-10-30 |
JP2009514937A (ja) | 2009-04-09 |
ZA200803671B (en) | 2009-03-25 |
DOP2006000243A (es) | 2007-05-31 |
PE20070715A1 (es) | 2007-08-11 |
TW200804353A (en) | 2008-01-16 |
AU2006310215A1 (en) | 2007-05-10 |
IL191059A0 (en) | 2008-12-29 |
CA2624621A1 (en) | 2007-05-10 |
ECSP088412A (es) | 2008-05-30 |
CA2624621C (en) | 2010-11-30 |
MA29926B1 (fr) | 2008-11-03 |
ES2371932T3 (es) | 2012-01-11 |
EA200801011A1 (ru) | 2009-02-27 |
NL2000284A1 (nl) | 2007-05-07 |
AR057855A1 (es) | 2007-12-19 |
ATE525372T1 (de) | 2011-10-15 |
BRPI0618129A2 (pt) | 2011-08-16 |
WO2007052123A2 (en) | 2007-05-10 |
NL2000284C2 (nl) | 2007-09-28 |
AP2008004468A0 (en) | 2008-06-30 |
WO2007052123A3 (en) | 2007-07-12 |
US20070105872A1 (en) | 2007-05-10 |
EP1945630B1 (en) | 2011-09-21 |
EP1945630A2 (en) | 2008-07-23 |
GT200600475A (es) | 2007-07-06 |
US7572797B2 (en) | 2009-08-11 |
UY29893A1 (es) | 2007-06-29 |
KR20080066073A (ko) | 2008-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |