TNSN06186A1 - Pyrido [2,3-d] pyrimidine -2, 4-diamines servant d'inhibiteurs de pde 2 - Google Patents
Pyrido [2,3-d] pyrimidine -2, 4-diamines servant d'inhibiteurs de pde 2Info
- Publication number
- TNSN06186A1 TNSN06186A1 TNP2006000186A TNSN06186A TNSN06186A1 TN SN06186 A1 TNSN06186 A1 TN SN06186A1 TN P2006000186 A TNP2006000186 A TN P2006000186A TN SN06186 A TNSN06186 A TN SN06186A TN SN06186 A1 TNSN06186 A1 TN SN06186A1
- Authority
- TN
- Tunisia
- Prior art keywords
- leurs
- des
- pyrido
- diamines
- pyrimidine
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- UDJFFSGCRRMVFH-UHFFFAOYSA-N pyrido[2,3-d]pyrimidine Chemical compound N1=CN=CC2=CC=CN=C21 UDJFFSGCRRMVFH-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
L'invention propose des composes de formule (I), Leurs précurseurs médicamenteux et les sels pharmaceutiquement acceptables des composés ou précurseurs médicamenteux, formule dans laquelle n, X et Y répondent aux définitions figurant dans le présent mémoire ; des compositions pharmaceutiques les contenant ; leurs associations ; et leurs utilisations.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52999403P | 2003-12-16 | 2003-12-16 | |
| PCT/IB2004/004013 WO2005061497A1 (fr) | 2003-12-16 | 2004-12-06 | Pyrido[2,3-d]pyrimidine-2,4-diamines en tant qu'inhibiteurs de la pde 2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN06186A1 true TNSN06186A1 (fr) | 2007-11-15 |
Family
ID=34710150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2006000186A TNSN06186A1 (fr) | 2003-12-16 | 2006-06-16 | Pyrido [2,3-d] pyrimidine -2, 4-diamines servant d'inhibiteurs de pde 2 |
Country Status (39)
| Country | Link |
|---|---|
| US (1) | US20070135457A1 (fr) |
| EP (1) | EP1697356B1 (fr) |
| JP (1) | JP4073944B2 (fr) |
| KR (1) | KR100816179B1 (fr) |
| CN (1) | CN100439366C (fr) |
| AP (1) | AP2006003632A0 (fr) |
| AR (1) | AR046766A1 (fr) |
| AT (1) | ATE387446T1 (fr) |
| AU (1) | AU2004303609A1 (fr) |
| BR (1) | BRPI0417663A (fr) |
| CA (1) | CA2549510A1 (fr) |
| CL (1) | CL2008001920A1 (fr) |
| DE (1) | DE602004012154T2 (fr) |
| DK (1) | DK1697356T3 (fr) |
| EA (1) | EA010424B1 (fr) |
| EC (1) | ECSP066643A (fr) |
| ES (1) | ES2299888T3 (fr) |
| GE (1) | GEP20094720B (fr) |
| GT (1) | GT200400268A (fr) |
| HN (1) | HN2004000538A (fr) |
| HR (1) | HRP20080142T3 (fr) |
| IL (1) | IL175813A0 (fr) |
| IS (1) | IS8474A (fr) |
| MA (1) | MA28270A1 (fr) |
| MX (1) | MXPA06006777A (fr) |
| NL (1) | NL1027787C2 (fr) |
| NO (1) | NO20063231L (fr) |
| PE (1) | PE20050681A1 (fr) |
| PL (1) | PL1697356T3 (fr) |
| PT (1) | PT1697356E (fr) |
| RS (1) | RS50575B (fr) |
| SI (1) | SI1697356T1 (fr) |
| SV (1) | SV2005001979A (fr) |
| TN (1) | TNSN06186A1 (fr) |
| TW (1) | TWI291961B (fr) |
| UA (1) | UA83091C2 (fr) |
| UY (1) | UY28671A1 (fr) |
| WO (1) | WO2005061497A1 (fr) |
| ZA (1) | ZA200604970B (fr) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2562428T3 (es) * | 2005-12-15 | 2016-03-04 | Rigel Pharmaceuticals, Inc. | Inhibidores de cinasa y sus usos |
| US20100143488A1 (en) * | 2006-09-21 | 2010-06-10 | Toshiki Oguro | Promoter of hard tissue regeneration |
| JP5472638B2 (ja) * | 2008-03-18 | 2014-04-16 | 日産化学工業株式会社 | １−（置換フェニル）−１−置換シリルエーテル、アルコールまたはケトンの製造方法および中間体 |
| WO2010062366A1 (fr) * | 2008-10-31 | 2010-06-03 | Arginetix, Inc. | Compositions et procédés de traitement de troubles endothéliaux |
| EP2456440B1 (fr) | 2009-07-22 | 2015-08-19 | Merck Sharp & Dohme Corp. | Inhibiteurs de quinoléinone pde2 |
| US8440710B2 (en) | 2009-10-15 | 2013-05-14 | Hoffmann-La Roche Inc. | HSL inhibitors useful in the treatment of diabetes |
| US9540379B2 (en) | 2011-01-31 | 2017-01-10 | Boehringer Ingelheim International Gmbh | (1,2,4)triazolo[4,3-A]quinoxaline derivatives as inhibitors of phosphodiesterases |
| EA201391558A1 (ru) | 2011-04-20 | 2014-05-30 | Глэксо Груп Лимитед | Тетрагидропиразоло[1,5-а]пиримидины как противотуберкулезные соединения |
| WO2013161913A1 (fr) | 2012-04-25 | 2013-10-31 | 武田薬品工業株式会社 | Composé hétérocyclique azoté |
| EP2873669A4 (fr) | 2012-07-13 | 2015-11-25 | Takeda Pharmaceutical | Composé hétérocyclique |
| US20140045856A1 (en) | 2012-07-31 | 2014-02-13 | Boehringer Ingelheim International Gmbh | 4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes |
| US9834520B2 (en) | 2013-03-14 | 2017-12-05 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| EP3018126A4 (fr) | 2013-07-03 | 2016-12-07 | Takeda Pharmaceuticals Co | Composé hétérocyclique |
| ES2950424T3 (es) | 2013-07-03 | 2023-10-09 | Takeda Pharmaceuticals Co | Compuesto de amida |
| JPWO2015012328A1 (ja) * | 2013-07-24 | 2017-03-02 | 武田薬品工業株式会社 | 複素環化合物 |
| WO2015096651A1 (fr) | 2013-12-23 | 2015-07-02 | Merck Sharp & Dohme Corp. | Composés pyrimidone carboxamide utilisés en tant qu'inhibiteurs de pde2 |
| US9849132B2 (en) | 2014-01-08 | 2017-12-26 | Intra-Cellular Therapies, Inc. | Products and pharmaceutical compositions |
| EP3174408B1 (fr) * | 2014-08-01 | 2018-12-05 | Firmenich SA | Dispersion solide de composés amide aromatiques |
| RU2702732C1 (ru) | 2014-12-06 | 2019-10-10 | Интра-Селлулар Терапиз, Инк. | Органические соединения |
| WO2016090380A1 (fr) | 2014-12-06 | 2016-06-09 | Intra-Cellular Therapies, Inc. | Composés organiques |
| WO2016145614A1 (fr) | 2015-03-17 | 2016-09-22 | Merck Sharp & Dohme Corp. | Composés de triazolyl pyrimidinone en tant qu'inhibiteurs de pde2 |
| US10287269B2 (en) | 2015-03-26 | 2019-05-14 | Merck Sharp & Dohme Corp. | Pyrazolyl pyrimidinone compounds as PDE2 inhibitors |
| WO2016179059A1 (fr) | 2015-05-05 | 2016-11-10 | Merck Sharp & Dohme Corp. | Composés d'hétéroaryl-pyrimidinone en tant qu'inhibiteurs de pde2 |
| WO2016183741A1 (fr) | 2015-05-15 | 2016-11-24 | Merck Sharp & Dohme Corp. | Composés de pyrimidinone amide en tant qu'inhibiteurs de pde2 |
| WO2016191935A1 (fr) | 2015-05-29 | 2016-12-08 | Merck Sharp & Dohme Corp. | Composés 6-alkyle dihydropyrazolopyrimidinone utilisés en tant qu'inhibiteurs de pde2 |
| WO2016192083A1 (fr) * | 2015-06-04 | 2016-12-08 | Merck Sharp & Dohme Corp. | Composés dihydropyrazolopyrimidinone utilisés en tant qu'en tant qu'inhibiteurs de pde2 |
| US10647727B2 (en) | 2015-06-25 | 2020-05-12 | Merck Sharp & Dohme Corp. | Substituted pyrazolo/imidazolo bicyclic compounds as PDE2 inhibitors |
| WO2017000276A1 (fr) | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Composés hétérocycliques bicycliques utilisés en tant qu'inhibiteurs de pde2 |
| WO2017000277A1 (fr) | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Bicyclo-composés de triazole substitués utilisés en tant qu'inhibiteurs de pde2 |
| EP3156405A1 (fr) | 2015-10-13 | 2017-04-19 | Boehringer Ingelheim International GmbH | Dérivés d'éther spirocycliques de pyrazolo [1,5-a] pyrimidine-3-carboxamide |
| GB201700814D0 (en) | 2017-01-17 | 2017-03-01 | Liverpool School Tropical Medicine | Compounds |
| US11419874B2 (en) | 2017-11-23 | 2022-08-23 | Oslo University Hospital Hf | Treatment of tachycardia |
| CN109758458B (zh) * | 2019-03-05 | 2021-02-23 | 中国人民解放军陆军军医大学第二附属医院 | 抑制Crif1与PKA相互作用的化合物的应用 |
| WO2022187411A1 (fr) * | 2021-03-02 | 2022-09-09 | Kumquat Biosciences Inc. | Hétérocycles et leurs utilisations |
| US11912708B2 (en) | 2022-04-20 | 2024-02-27 | Kumquat Biosciences Inc. | Macrocyclic heterocycles and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2749344A (en) * | 1953-01-02 | 1956-06-05 | Burroughs Wellcome Co | Pyrimidine compounds |
| US3021332A (en) * | 1954-01-04 | 1962-02-13 | Burroughs Wellcome Co | Pyrido (2, 3-d) pyrimidine compounds and method of making |
| US2926166A (en) * | 1954-01-04 | 1960-02-23 | Burroughs Wellcome Co | Pyrido (2, 3-d) pyrimidine compounds and method of making |
| US2924599A (en) * | 1956-07-16 | 1960-02-09 | Anchor Chemical Company Ltd | Derivatives of 1:3:5-triazanaphthalene |
| US2937284A (en) * | 1958-05-01 | 1960-05-17 | Burroughs Wellcome Co | 2, 4-diamino-5, 6-dialkylpyrido (2, 3-d) pyrimidines and method |
| US3288792A (en) * | 1962-07-05 | 1966-11-29 | Burroughs Wellcome Co | Method of preparing 2, 4-diamino-6-alkylpyrido (2, 3-d) pyrimidines |
| DE3422824A1 (de) * | 1984-06-20 | 1986-01-02 | Celamerck Gmbh & Co Kg, 6507 Ingelheim | Neue herbizid wirksame sulfonylharnstoffe |
| US6194166B1 (en) * | 1993-05-24 | 2001-02-27 | Takara Shuzo Co., Ltd. | Gene regulating aureobasidin sensitivity |
| US5547954A (en) * | 1994-05-26 | 1996-08-20 | Fmc Corporation | 2,4-Diamino-5,6-disubstituted-and 5,6,7-trisubstituted-5-deazapteridines as insecticides |
| US6262059B1 (en) * | 1995-06-07 | 2001-07-17 | Cell Pathways, Inc. | Method of treating a patient having precancerous lesions with quinazoline derivatives |
| US6184226B1 (en) * | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| PE20030008A1 (es) * | 2001-06-19 | 2003-01-22 | Bristol Myers Squibb Co | Inhibidores duales de pde 7 y pde 4 |
-
2004
- 2004-12-06 ES ES04801323T patent/ES2299888T3/es active Active
- 2004-12-06 UA UAA200606683A patent/UA83091C2/ru unknown
- 2004-12-06 PT PT04801323T patent/PT1697356E/pt unknown
- 2004-12-06 AT AT04801323T patent/ATE387446T1/de not_active IP Right Cessation
- 2004-12-06 GE GEAP20049461A patent/GEP20094720B/en unknown
- 2004-12-06 BR BRPI0417663-4A patent/BRPI0417663A/pt not_active IP Right Cessation
- 2004-12-06 AP AP2006003632A patent/AP2006003632A0/xx unknown
- 2004-12-06 JP JP2006544574A patent/JP4073944B2/ja not_active Expired - Fee Related
- 2004-12-06 KR KR1020067011800A patent/KR100816179B1/ko not_active IP Right Cessation
- 2004-12-06 DK DK04801323T patent/DK1697356T3/da active
- 2004-12-06 EA EA200600973A patent/EA010424B1/ru not_active IP Right Cessation
- 2004-12-06 WO PCT/IB2004/004013 patent/WO2005061497A1/fr active Application Filing
- 2004-12-06 RS RSP-2008/0172A patent/RS50575B/sr unknown
- 2004-12-06 MX MXPA06006777A patent/MXPA06006777A/es active IP Right Grant
- 2004-12-06 SI SI200430637T patent/SI1697356T1/sl unknown
- 2004-12-06 CA CA002549510A patent/CA2549510A1/fr not_active Abandoned
- 2004-12-06 AU AU2004303609A patent/AU2004303609A1/en not_active Abandoned
- 2004-12-06 PL PL04801323T patent/PL1697356T3/pl unknown
- 2004-12-06 CN CNB2004800376743A patent/CN100439366C/zh not_active Expired - Fee Related
- 2004-12-06 US US10/595,766 patent/US20070135457A1/en not_active Abandoned
- 2004-12-06 DE DE602004012154T patent/DE602004012154T2/de not_active Expired - Fee Related
- 2004-12-06 EP EP04801323A patent/EP1697356B1/fr active Active
- 2004-12-15 GT GT200400268A patent/GT200400268A/es unknown
- 2004-12-15 AR ARP040104668A patent/AR046766A1/es not_active Application Discontinuation
- 2004-12-15 NL NL1027787A patent/NL1027787C2/nl not_active IP Right Cessation
- 2004-12-15 UY UY28671A patent/UY28671A1/es not_active Application Discontinuation
- 2004-12-15 TW TW093138972A patent/TWI291961B/zh active
- 2004-12-16 HN HN2004000538A patent/HN2004000538A/es unknown
- 2004-12-16 SV SV2004001979A patent/SV2005001979A/es not_active Application Discontinuation
-
2005
- 2005-01-03 PE PE2005000028A patent/PE20050681A1/es not_active Application Discontinuation
-
2006
- 2006-05-18 IS IS8474A patent/IS8474A/is unknown
- 2006-05-22 IL IL175813A patent/IL175813A0/en unknown
- 2006-06-15 ZA ZA200604970A patent/ZA200604970B/en unknown
- 2006-06-15 EC EC2006006643A patent/ECSP066643A/es unknown
- 2006-06-16 TN TNP2006000186A patent/TNSN06186A1/fr unknown
- 2006-06-16 MA MA29113A patent/MA28270A1/fr unknown
- 2006-07-11 NO NO20063231A patent/NO20063231L/no not_active Application Discontinuation
-
2008
- 2008-03-28 HR HR20080142T patent/HRP20080142T3/xx unknown
- 2008-06-27 CL CL200801920A patent/CL2008001920A1/es unknown
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