MXPA06000988A - Derivados de nicotinamida utiles como inhibidores de pde4. - Google Patents

Derivados de nicotinamida utiles como inhibidores de pde4.

Info

Publication number
MXPA06000988A
MXPA06000988A MXPA06000988A MXPA06000988A MXPA06000988A MX PA06000988 A MXPA06000988 A MX PA06000988A MX PA06000988 A MXPA06000988 A MX PA06000988A MX PA06000988 A MXPA06000988 A MX PA06000988A MX PA06000988 A MXPA06000988 A MX PA06000988A
Authority
MX
Mexico
Prior art keywords
inhibitors
pdea4
derivatives useful
nicotinamide derivatives
nicotinamide
Prior art date
Application number
MXPA06000988A
Other languages
English (en)
Inventor
Paul John Mathias
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MXPA06000988A publication Critical patent/MXPA06000988A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

Esta invencion se refiere a derivados de nicotinamida de formula general (I): (ver formula (I) en la que R1, R2 y R3 tienen los significados definidos en la presente memoria, y a procesos para la preparacion de intermedios utilizados en la preparacion de composiciones que los contienen, y a los usos de estos derivados.
MXPA06000988A 2003-07-25 2004-07-13 Derivados de nicotinamida utiles como inhibidores de pde4. MXPA06000988A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0317509.8A GB0317509D0 (en) 2003-07-25 2003-07-25 Nicotinamide derivatives useful as PDE4 inhibitors
PCT/IB2004/002365 WO2005010001A1 (en) 2003-07-25 2004-07-13 Nicotinamide derivatives useful as pdea4 inhibitors

Publications (1)

Publication Number Publication Date
MXPA06000988A true MXPA06000988A (es) 2006-04-11

Family

ID=27772736

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06000988A MXPA06000988A (es) 2003-07-25 2004-07-13 Derivados de nicotinamida utiles como inhibidores de pde4.

Country Status (7)

Country Link
EP (1) EP1651647A1 (es)
JP (1) JP2006528623A (es)
BR (1) BRPI0412933A (es)
CA (1) CA2533681A1 (es)
GB (1) GB0317509D0 (es)
MX (1) MXPA06000988A (es)
WO (1) WO2005010001A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
PL1888033T3 (pl) * 2005-06-09 2014-09-30 Meda Ab Sposób i kompozycja do leczenia chorób zapalnych
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
CA2615122A1 (en) * 2005-08-03 2007-02-15 Immunogen, Inc. Immunoconjugate formulations
US8273774B2 (en) * 2008-05-27 2012-09-25 Astrazeneca Ab Phenoxypyridinylamide compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA003528B1 (ru) * 1997-04-04 2003-06-26 Пфайзер Продактс Инк. Производные никотинамида, их применение, фармацевтическая композиция, способ лечения и способ ингибирования изоферментов фдэ4 d
DE60317466T2 (de) * 2002-02-11 2008-03-06 Pfizer Inc. Nicotinamidderivate, die als PDE4--Inhibitoren einsetzbar sind
GB0203193D0 (en) * 2002-02-11 2002-03-27 Pfizer Ltd Nicotinamide derivatives useful as pde4 inhibitors

Also Published As

Publication number Publication date
GB0317509D0 (en) 2003-08-27
EP1651647A1 (en) 2006-05-03
WO2005010001A1 (en) 2005-02-03
CA2533681A1 (en) 2005-02-03
JP2006528623A (ja) 2006-12-21
BRPI0412933A (pt) 2006-09-26

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal